scholarly journals Synchronous Gastric Gastrointestinal Stromal Tumor and Colon Adenocarcinoma: A Case Report

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Thivi Vasilakaki ◽  
Kalliroi Koulia ◽  
Aikaterini Tsavari ◽  
Elissavet Arkoumani ◽  
Efstratios Kouroumpas ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Regional Lymph Node ◽  
Wedge Resection ◽  
Rare Event ◽  
Colon Adenocarcinoma ◽  
Additional Treatment ◽  
Stromal Tumor ◽  
Gastric Body ◽  
Ascending Colon ◽  
Mesenchymal Tumors

Gastrointestinal stromal tumors (GISTs) represent the majority of primary mesenchymal tumors of the gastrointestinal tract. They are generally considered to be solitary tumors and therefore the synchronous occurrence with other primary malignancies of gastrointestinal track is considered a rare event. Here we present the case of a 75-year-old man admitted to our hospital with a 10-day history of gastrointestinal bleeding. Colonoscopy revealed an ulcerative mass of 4 cm in diameter in the ascending colon. Gastroscopy revealed a bulge in the gastric body measuring 1 cm in diameter with normal overlying mucosa. Surgical intervention was suggested and ileohemicolectomy with regional lymph node resection along with gastric wedge resection was performed. Pathologic examination of the ascending colon mass showed an invasive moderately differentiated adenocarcinoma stage III B (T3N1M0). Grossly resected wedge of stomach showed a well circumscribed intramural tumor which microscopically was consistent with essentially benign gastrointestinal stromal tumor (according to Miettinen criteria). The patient did not receive additional treatment. Two years later the patient showed no evidence of recurrence or metastasis.

scholarly journals Case report and literature review: patient with gastroduodenal intussusception due to the gastrointestinal stromal tumor of the lesser curvature of the gastric body

BMC Surgery ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Mihajlo Đokić ◽  
Jerica Novak ◽  
Miha Petrič ◽  
Branislava Ranković ◽  
Miha Štabuc ◽  
...  
Keyword(s):  
Literature Review ◽  
Gastrointestinal Stromal Tumor ◽  
Gastric Wall ◽  
Rare Event ◽  
Outlet Obstruction ◽  
Low Risk ◽  
Stromal Tumor ◽  
Gastric Body ◽  
Gastroduodenal Intussusception ◽  
Lesser Curvature

Abstract Background Intussusception in adult patient is rare. Gastroduodenal intussusception due to the gastrointestinal stromal tumors is infrequently described in the literature. Authors present a case of gastroduodenal intussusception due to the low-risk gastrointestinal stromal tumor of the lesser curvature of the gastric body with literature review. Case presentation Sixty-two-year-old male was admitted to our hospital with symptoms of acute gastric outlet obstruction. Imaging studies confirmed a lesion of the gastric wall producing gastroduodenal intussusception with pylorus obstruction. Upon laparotomy a tumor mass of the lesser curvature of the gastric body that invaginated through the pylorus into the duodenum was found. Desinvagination and resection of the tumor with the adequate resection margins were performed. Histology reveled a low-risk gastrointestinal stromal tumor. Due to favorable outcome only observation was suggested by the multidisciplinary team. Conclusions Gastroduodenal intussusception due to the gastrointestinal stromal tumor of the gastric wall is a rare event. Surgical resection is the treatment of choice. In selected cases laparosopic resection of the tumor can be performed.

scholarly journals A Case of Benign Schwannoma of the Ascending Colon Treated With Laparoscopic-Assisted Wedge Resection

2013 ◽  
Vol 98 (4) ◽  
pp. 315-318 ◽  
Author(s):  
Se-Jin Baek ◽  
Won Hwangbo ◽  
Jin Kim ◽  
In-Sun Kim
Keyword(s):  
Submucosal Tumor ◽  
Wedge Resection ◽  
Ascending Colon ◽  
Mesenchymal Tumors ◽  
Benign Schwannoma ◽  
S 100 ◽  
Colon And Rectum ◽  
Laparoscopic Assisted ◽  
Specific Symptoms ◽  
Diffuse Positivity

Abstract Isolated colonic schwannomas are rare gastrointestinal mesenchymal tumors. Only a small number of cases have been reported. Occurrence of these tumors is more common in the stomach than in the large intestine. These spindle cell lesions are distinct from leiomyoma, leiomyosarcoma, and gastrointestinal stromal tumors because the tumor cells have a distinct immunophenotype, with strong diffuse positivity for S-100 and vimentin, as well as corroborative negative staining of CD117 and smooth muscle markers. We present a case of colonic schwannoma in a 70-year-old woman who had no specific symptoms. The patient was diagnosed with a submucosal tumor in the ascending colon on colonoscopy and abdominal computed tomography. Laparoscopic-assisted wedge resection of colon was performed. The very rare pathologic diagnosis of ascending schwannoma was made postoperatively. This case is interesting because schwannomas of the colon and rectum are extremely rare and are treated by laparoscopic-assisted wedge resection.

scholarly journals Gastric schwannoma: a benign tumor often misdiagnosed as gastrointestinal stromal tumor

2015 ◽  
Vol 5 (3) ◽  
Author(s):  
Apurva S. Shah ◽  
Pravin M. Rathi ◽  
Vaibhav S. Somani ◽  
Astha M. Mulani
Keyword(s):  
Differential Diagnosis ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Rare Case ◽  
Benign Tumor ◽  
Stromal Tumor ◽  
Mesenchymal Tumors ◽  
Stromal Tumors ◽  
Gastric Schwannoma ◽  
Gastric Mass

Gastric schwannomas are rare mesenchymal tumors that arise from the nerve plexus of gut wall. They present with nonspecific symptoms and are often detected incidentally. Preoperative investigation is not pathognomic and many are therefore misdiagnosed as gastrointestinal stromal tumors. We report a rare case of a 37-year old woman who underwent laparotomy for complex bilateral ovarian cyst with resection of gastric-gastrointestinal stromal tumor preoperatively, but confirmed to have a gastric schwannomas postoperatively. This case underscores the differential diagnosis of submucosal, exophytic gastric mass as schwannoma.

scholarly journals TOMOGRAPHIC FINDINGS OF GASTRIC GASTROINTESTINAL STROMAL TUMOR AND CORRELATION WITH THE MITOTIC INDEX

2013 ◽  
Vol 50 (4) ◽  
pp. 244-250 ◽  
Author(s):  
Gustavo Lemos PELANDRÉ ◽  
Maria Célia DJAHJAH ◽  
Emerson Leandro GASPARETTO ◽  
Marcelo Souto NACIF ◽  
Edson MARCHIORI ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Mitotic Index ◽  
Statistical Correlation ◽  
Gastric Fundus ◽  
The Body ◽  
Stromal Tumor ◽  
Gastric Body ◽  
Dense Area ◽  
Stromal Tumors ◽  
Mesenteric Fat

ContextGastrointestinal stromal tumors are uncommon abdominal neoplasms and can affect any portion of the gastrointestinal tract.ObjectivesDescribe the tomographic findings of the gastrointestinal stromal tumor of gastric origin, correlating it with the mitotic index.MethodsTwenty-one patients were selected within the period of January 2000 and 2008, with histopathological and immunohistochemical diagnosis of gastric gastrointestinal stromal tumors, who presented computed tomography done before the treatment. The tomographic variables analyzed were lesion topography, dimensions, contours, morphology, pattern and intensity enhancement through venous contrast, growth pattern, invasion of adjacent organs, presence of ulceration, fistula, calcifications, infiltration of mesenteric fat, lymphadenopathy and metastasis. The mitotic index was determined through optic microscopy, counting the number of mitosis figures in 50 high power fields.ResultsThe tumors were located in the body (66.7%) or gastric fundus (33.3%), with dimensions varying between 4.2 and 21.2 cm (average of 10.5 cm). The growth was predominantly extraluminal (47.6%) or intra/extra luminal (28.6%). The enhancement by venous contrast was heterogeneous in 66.7%. The statistical analysis showed that irregular morphology (P = 0.027) and infiltration of mesenteric fat (P = 0.012) presented correlation with the high mitotic index.ConclusionsIn the present study, most part of the tumors were located in the gastric body, with average size of 10.5 cm, presenting central hypo dense area, heterogeneous enhancement through contrast and predominantly extra luminal growth. Irregular morphology and infiltration of mesenteric fat present statistical correlation with high mitotic level.

scholarly journals Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Areen Abdulelah Murshid ◽  
Hatim Q. Al-Maghraby
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Desmoid Tumor ◽  
Case Reports ◽  
Previous History ◽  
Subsequent Development ◽  
Stromal Tumor ◽  
Desmoid Tumors ◽  
Mesenchymal Tumors ◽  
First Case ◽  
History Of

Desmoid tumors (deep fibromatosis) of the mesentery are rare mesenchymal tumors. They are often misdiagnosed, especially with a previous history of resection for gastrointestinal stromal tumor (GIST). Immunohistochemistry can help differentiate between these two tumors. In this article, we present a case we had encountered: a Desmoid tumor developing in a patient with a history of GIST 3 years ago. It is the first case of GIST with subsequent development of Desmoid tumor to be reported in Saudi Arabia. We discuss the two entities of Desmoid tumor and GIST by comparing their definitions, clinical presentations, histological features, immunohistochemistry stains, molecular pathogenesis, prognosis, and treatment. We also discuss the relationship between GIST and the subsequent development of Desmoid tumors and compare our case with case reports in literature.

Large Omental Metastases of a Gastrointestinal Stromal Tumor

Medicina ◽  
2011 ◽  
Vol 47 (11) ◽  
pp. 86
Author(s):  
Povilas Ignatavičius ◽  
Tomas Petraitis ◽  
Žilvinas Saladžinskas ◽  
Lilija Butkevičienė ◽  
Kristina Žvinienė
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Interstitial Cells Of Cajal ◽  
Metastatic Tumor ◽  
Stromal Tumor ◽  
Mesenchymal Tumors ◽  
Stromal Tumors ◽  
Cells Of Cajal

Gastrointestinal stromal tumors are rare tumors, originating from the interstitial cells of Cajal. They are the most common mesenchymal tumors of the gastrointestinal tract. Metastatic tumor is treated with imatinib mesylate. A case of large metastases of a gastrointestinal stromal tumor to the omentum, diagnosis and treatment principles are presented in this case report.

scholarly journals A Giant Gastrointestinal Stromal Tumor of the Stomach with Extramural Growth

2016 ◽  
Vol 10 (2) ◽  
pp. 344-351 ◽  
Author(s):  
Ryosuke Miyazaki ◽  
Seiji Arihiro ◽  
Eri Hayashi ◽  
Takuya Kitahara ◽  
Sayumi Oki ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Tumor Resection ◽  
Partial Gastrectomy ◽  
Major Axis ◽  
Anterior Wall ◽  
Stromal Tumor ◽  
Gastric Body ◽  
Abdominal Organs ◽  
Loss Of Appetite ◽  
Upper Abdominal

A 76-year-old man presented to our hospital with abdominal distention and loss of appetite. The 10% of weight lost relative to this patient in 1 month. Abdominal computed tomography and magnetic resonance imaging revealed a giant mass, with a major axis of 23 cm, containing solid components, not involving the upper abdominal organs. Esophagogastroduodenoscopy showed extramural compression from the middle gastric body to the antrum, as well as a normal mucosal surface. These findings were suggestive of a gastrointestinal stromal tumor attached to the anterior wall of the stomach without metastasis or invasion. Partial gastrectomy was performed for tumor resection, and the patient was subsequently treated with adjuvant imatinib. We report a rare case of a large extramural gastrointestinal stromal tumor of the stomach that was larger than 20 cm in diameter and present a pertinent literature review.

THE EXPRESS OF SOME MARKERS, RISK STRATIFICATION AND THE RELATION WITH THE OTHER RISK FACTORS IN GIST

2016 ◽  
pp. 109-115
Author(s):  
Van Mao Nguyen ◽  
Xuan Tien Tran
Keyword(s):  
Risk Factors ◽  
Risk Stratification ◽  
Gastrointestinal Stromal Tumor ◽  
Cross Sectional Study ◽  
Stromal Tumor ◽  
Surgical Pathology ◽  
Risk Level ◽  
Mesenchymal Tumors ◽  
Cross Sectional ◽  
Choice Of Treatment

Background: Gastrointestinal Stromal Tumor (GIST) is the most frequent one among the digestive mesenchymal tumors. GIST usually locates under the mucosa of the stomach, esophagus, small intestine, colorectal intestine and evenly sometimes at the mesentery, omentum. Microscopically, GIST appeares as various features. In order to determine the origin of the tumor cell, surgical pathology especially the immunohistochemistry play a key role for the best choice of treatment with the targeted therapy. Objectives: - To study some of the common characteristics of the surgical pathology and immunohistochemistry of GIST. – To apply the GIST Risk Stratification of AFIP 2006 and determine the relation with some of the traditional risk factors. Materials and Method: cross-sectional study of 39 patients diagnosed with GIST at Hue Central Hospital from 6/2011 to 7/2015. Results: the average age 55.87±11.91, the most frequent age 41-60 in both men and women. The tumor size >2-5cm was the most rate 64.1%, GIST mostly located at the stomach, accounting for 48.7%. The spindle cell GISTs were the highest type 87.2%. Immunohistochemistry shown that the positive of CD117, Vimentine, CD34 were 100%, 94.7% and 61.5% respectively. All GISTs were negative for Desmine. The high risk GISTs were the most frequent accounting for 46.2%, following the moderate ones 28.2%, then the low 20.5%, the very low only 5.1%. This study also shown that, there were the relation between the tumor risk level with the tumor necrosis and the mucosa invasion. Conclusion: The application of the Immunohistochemistry with the marker CD117 and the GIST Risk Stratification need carry out for the digestive mesenchymal tumors to choose the best treatment for the patients. Key words: gastrointestinal stromal tumor (GIST), mesenchymal tumor, histopathology, immunohistochemistry

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