scholarly journals ‘Bobo-Newton Syndrome’: An Unwanted Gift from Man’s Best Friend

2013 ◽  
Vol 24 (4) ◽  
pp. 209-214 ◽  
Author(s):  
Kristin Y Popiel ◽  
Donald C Vinh
Keyword(s):  
Present Article ◽  
Invasive Disease ◽  
Clinical Suspicion ◽  
Genetic Identification ◽  
Dog Bite ◽  
Capnocytophaga Canimorsus ◽  
Oral Flora ◽  
Blood Isolate ◽  
Negative Bacillus ◽  
Clinical Syndromes

Capnocytophaga canimorsusis a facultative Gram-negative bacillus that is typically a constituent of the oral flora of dogs and cats. It was first isolated by Bobo and Newton in 1976 from a man presenting with meningitis following a dog bite. Transmission to humans follows various animal-related injuries, which may be gross or subtle.C canimorsuscan cause a spectrum of syndromes ranging from skin and soft tissue infection to invasive disease such as meningitis or endocarditis. The present article reports a case ofC canimorsusmeningitis in a patient with the classic risk factor of alcoholic liver cirrhosis. Clinical suspicion was confirmed by culture and genetic identification of the blood isolate. The present article reviews theCapnocytophagagenus, the clinical syndromes most commonly associated with this zoonotic organism, its laboratory identification and treatment.

Rare case of Capnocytophaga canimorsus meningitis in a man without risk factors

2021 ◽  
Vol 14 (5) ◽  
pp. e241686
Author(s):  
Faheem Malik ◽  
William Orchard ◽  
George Jacob
Keyword(s):  
Risk Factors ◽  
Rare Case ◽  
Immunocompetent Patient ◽  
Clinical Suspicion ◽  
Dog Bite ◽  
Capnocytophaga Canimorsus ◽  
Animal Exposure

Capnocytophaga canimorsus meningitis is an uncommon but potentially serious cause of meningitis, which is considered particularly rare in healthy and immunocompetent individuals. We present a case of C. canimorsus meningitis in a young, immunocompetent patient which was acquired following a dog bite. We review the literature and propose that underdiagnosis of this condition is likely. To avoid misdiagnosis, and thus improper management, clinicians should ensure that they identify animal exposure in all meningitic patients, and adopt a higher clinical suspicion in the absence of classical risk factors.

Capnocytophaga canimorsus meningitis and bacteraemia without a dog bite in an immunocompetent individual

2021 ◽  
Vol 14 (7) ◽  
pp. e242432
Author(s):  
Fiona O'Riordan ◽  
Aoife Ronayne ◽  
Arthur Jackson
Keyword(s):  
Complete Recovery ◽  
Human Infection ◽  
Blood Cultures ◽  
Invasive Infection ◽  
Dog Bite ◽  
Capnocytophaga Canimorsus ◽  
Oral Flora ◽  
Immunocompetent Individual ◽  
Laboratory Confirmation ◽  
History Of

We describe the case of an immunocompetent 75-year-old man with Capnocytophaga canimorsus bacteraemia and meningitis. C. canimorsus is commonly found in the oral flora of dogs with human infection typically occurring following a bite. Unusually, while our patient was a dog owner, there was no history of bite nor scratch mark. Admission blood cultures flagged positive for Gram-negative bacilli, but prolonged molecular analysis was required before C. canimorsus was isolated in blood and cerebrospinal fluid. There is a high mortality rate in invasive infection, and in our patient’s case, antibiotic therapy was commenced prior to laboratory confirmation with our patient making a complete recovery. This case highlights the importance of including C. canimorsus in the differential diagnosis of unwell patients who keep dogs, even without a bite. This case occurred amid heightened awareness of COVID-19, which may represent predisposition for zoonoses during social isolation and increased human–pet contact.

scholarly journals Meningitis Caused by Salmonella Newport in a Five-Year-Old Child

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Ana De Malet ◽  
Sheila Ingerto ◽  
Israel Gañán
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurological Disorders ◽  
Invasive Disease ◽  
Salmonella Typhi ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Salmonella Newport ◽  
Gram Negative Bacillus ◽  
The Central Nervous System

Salmonella Newport is a Gram-negative bacillus belonging to the Enterobacteria family and the nontyphi Salmonella (NTS), usually related to gastroenteritis. Main difference between NTS and Salmonella typhi is that the last one evolves to an invasive disease easier than NTS. These can progress to bacteremias in around 5% of cases and secondary focuses can appear occasionally, as in meningitis. An infection of the central nervous system is uncommon, considering its incidence in 0.6–8% of the cases; most of them are described in developing countries and mainly in childhood, especially neonates. Bacterial meningitis by NTS mostly affects immunosuppressed people in Europe. Prognosis is adverse, with a 50% mortality rate, mainly due to complications of infection: hydrocephalus, ventriculitis, abscesses, subdural empyema, or stroke. Choice antibiotic treatments are cefotaxime, ceftriaxone, or ceftazidime. The aim of this paper is to present a case of meningitis caused by Salmonella Newport diagnosed in a five-year-old girl living in a rural area of the province of Ourense (Spain), with favorable evolution and without neurological disorders.

scholarly journals Image Gallery: Annular erythema related to Capnocytophaga canimorsus bacteraemia after a dog bite

2018 ◽  
Vol 179 (5) ◽  
pp. e196-e196 ◽  
Author(s):  
R. Tsutsumi ◽  
Y. Yoshida ◽  
M. Suzuki ◽  
K. Imaoka ◽  
O. Yamamoto
Keyword(s):  
Dog Bite ◽  
Capnocytophaga Canimorsus ◽  
Annular Erythema

scholarly journals Hypertensive Emergency and Type 2 Myocardial Infarction Resulting From Pheochromocytoma and Concurrent Capnocytophaga Canimorsus Infection

2014 ◽  
Vol 8 (1) ◽  
pp. 43-47 ◽  
Author(s):  
Graham J Fent ◽  
Hazlyna Kamaruddin ◽  
Pankaj Garg ◽  
Ahmed Iqbal ◽  
Nicholas F Kelland ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Clinical Presentation ◽  
Plaque Rupture ◽  
Interesting Case ◽  
Hypertensive Emergency ◽  
Cardiac Biomarkers ◽  
Dog Bite ◽  
Capnocytophaga Canimorsus ◽  
Review Current

A diagnosis of myocardial infarction is made using a combination of clinical presentation, electrocardiogram and cardiac biomarkers. However, myocardial infarction can be caused by factors other than coronary artery plaque rupture and thrombosis. We describe an interesting case presenting with hypertensive emergency and type 2 myocardial infarction resulting from Pheochromocytoma associated with Capnocytophaga canimorsus infection from a dog bite. We also review current literature on the management of hypertensive emergency and Pheochromocytoma.

Severe Sepsis with DIC due to Capnocytophaga Canimorsus after Dog Bite in an Immune Competent Patient leading to subsequent Lower Limb Amputationa

2018 ◽  
Vol 08 (02) ◽  
Author(s):  
Leonie Grossekettler ◽  
Vedat Schwenger ◽  
Bastian Schmack ◽  
Hugo A Katus ◽  
Michael R Preusch
Keyword(s):  
Severe Sepsis ◽  
Lower Limb ◽  
Dog Bite ◽  
Capnocytophaga Canimorsus ◽  
Competent Patient

scholarly journals Two Dog-Related Infections Leading to Death: Overwhelming Capnocytophaga canimorsus Sepsis in a Patient With Cystic Echinococcosis

Medicina ◽  
2012 ◽  
Vol 48 (2) ◽  
pp. 11 ◽  
Author(s):  
Raimonda Matulionytė ◽  
Ingrida Lisauskienė ◽  
Gintautas Kėkštas ◽  
Arvydas Ambrozaitis
Keyword(s):  
Echinococcus Granulosus ◽  
Cystic Echinococcosis ◽  
Unknown Etiology ◽  
Healthy Individuals ◽  
Capnocytophaga Canimorsus ◽  
Laboratory Findings ◽  
Oral Flora ◽  
Recent Exposure ◽  
The Family ◽  
Fatal Sepsis

Capnocytophaga canimorsus is a fastidious, capnophilic, fusiform, and filamentous gram-negative rod. It is part of the normal oral flora of dogs and cats and can cause an infection in humans, but is of generally low virulence in healthy individuals. A case of fatal sepsis due to Capnocytophaga canimorsus in a 46-year-old woman with clinically silent cystic echinococcosis discovered postmortem is present. She had been bitten by a dog 3 days before the symptoms appeared. The family had owned the dog for 4 years. A preliminary diagnosis of septic shock of unknown etiology with multisystem organ failure was established. Despite all the efforts, the patient died on the seventh day of hospitalization. Laboratory findings received postmortem showed Capnocytophaga canimorsus isolated from the blood culture after 7 incubation days. Autopsy showed a cyst in the liver with a fibrotic wall and necrotic eosinophilic interiors containing fragments of Echinococcus granulosus scolices. In conclusion, an interaction possibly established long ago between the host and Echinococcus granulosus conditioned immunosuppression mechanisms developed by the parasite in this case, which can explain such an aggressive course of the infection with Capnocytophaga. Two dog-related infections were fatal in the middle-aged dog owner considered healthy before this hospitalization. Vigilance concerning recent exposure to dogs or cats and potential immunosuppression risk factors must be maintained in a patient presenting with clinical features of fulminant sepsis.

scholarly journals Emergence of Non-Serotype b EncapsulatedHaemophilus influenzaeas a Cause of Pediatric Meningitis in Northwestern Ontario

2013 ◽  
Vol 24 (1) ◽  
pp. 13-16 ◽  
Author(s):  
Pouya Sadeghi-Aval ◽  
Raymond SW Tsang ◽  
Frances B Jamieson ◽  
Marina Ulanova
Keyword(s):  
Bacterial Meningitis ◽  
Haemophilus Influenzae ◽  
Present Article ◽  
Genetic Background ◽  
Antibiotic Sensitivity ◽  
Invasive Disease ◽  
Northwestern Ontario ◽  
Clonal Nature ◽  
Serotype B ◽  
Meningitis In Children

Before the introduction of the conjugate vaccine,Haemophilus influenzaeserotype b (Hib) was the leading cause of bacterial meningitis in children. Although successful in reducing Hib cases, the vaccine confers no protection against other serotypes ofH influenzae, such as a (Hia), or f (Hif). The emergence of invasive disease caused by non-Hib in northwestern Ontario (38 cases between 2002 and 2008) with predominance of Hia was previously reported by the authors. At that time, no cases of pediatric meningitis caused byH influenzaewere recorded in the region. Continued surveillance identified 12 new cases of invasive non-Hib between January 2009 and July 2011. Among these cases, three young children developed meningitis with severe complications caused by Hia or Hif. The present article describes these cases along with the characteristics of recentH influenzaeisolates from the region, (ie, their genetic background and antibiotic sensitivity). The findings point to the clonal nature of circulating Hia strains as well as to an increase in frequency and severity of pediatric invasiveH influenzaeinfections in northwestern Ontario.

Dog-bite induced Capnocytophaga canimorsus septicaernia

1992 ◽  
Vol 22 (1) ◽  
pp. 86-87 ◽  
Author(s):  
K. CLARKE ◽  
D. DEVONSHIRE ◽  
A. VEITCH ◽  
R. BELLOMO ◽  
G. PARKIN
Keyword(s):  
Dog Bite ◽  
Capnocytophaga Canimorsus

Purpura Fulminans and Symmetrical Peripheral Gangrene Caused by Capnocytophaga canimorsus (Formerly DF-2) Septicemia—A Complication of Dog Bite

Medicine ◽  
1991 ◽  
Vol 70 (5) ◽  
pp. 287-292 ◽  
Author(s):  
BART-JAN KULLBERG ◽  
RUDI G. J. WESTENDORP ◽  
JAN W. VANʼT WOUT ◽  
A. Edo Meinders
Keyword(s):  
Purpura Fulminans ◽  
Dog Bite ◽  
Capnocytophaga Canimorsus ◽  
Peripheral Gangrene
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