scholarly journals The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Chi-Hua Yen ◽  
Nae-Cherng Yang ◽  
Bor-Jen Lee ◽  
Jui-Yuan Lin ◽  
Simon Hsia ◽  
...  

The purpose of this study was to investigate the levels of coenzyme Q10 and vitamin E and the antioxidant status in subjects with metabolic syndrome (MS). Subjects with MS (n=72) were included according to the criteria for MS. The non-MS group (n=105) was comprised of healthy individuals with normal blood biochemical values. The plasma coenzyme Q10, vitamin E concentrations, lipid profiles, and antioxidant enzymes levels (catalase, superoxide dismutase, and glutathione peroxidase) were measured. The subjects with MS had significantly higher concentrations of plasma coenzyme Q10 and vitamin E than those in the non-MS group, but these differences were not significant after being normalized for triglyceride level. The levels of antioxidant enzymes were significantly lower in the MS group than in the non-MS group. The subjects with the higher antioxidant enzymes activities had significant reductions in the risk of MS (P<0.01) after being adjusted for coenzyme Q10 and vitamin E. In conclusion, the subjects with MS might be under higher oxidative stress resulting in low levels of antioxidant enzyme activities. A higher level of antioxidant enzymes activities was significantly associated with a reduction in the risk of MS independent of the levels of coenzyme Q10 and vitamin E.

2020 ◽  
Vol 29 (1) ◽  
pp. 117-123 ◽  
Author(s):  
Shamima Nasrin ◽  
Shukanta Saha ◽  
Hasna Hena Begum ◽  
Rifat Samad

One of the major problems associated with rice cultivation and production is the deficiency of water resources. In here the effect of drought stress on growth, protein-, proline-, pigment contents and antioxidant enzymes activities in rice var. BRRI Dhan-24 was determined and analyzed under drought and wellwatered condition. Drought stress caused the decrease of growth and pigment contents - chlorophyll-a, b, a/b, total chlorophyll and carotenoids content of leaves of rice plants. On the other hand, the accumulation of protein, proline contents and antioxidant enzymes activities was increased under drought stress. It may be suggested that antioxidant enzymes activities and proline accumulation were associated with the growth of the plant and consequently with the mechanisms of drought tolerance in rice. Dhaka Univ. J. Biol. Sci. 29(1): 117-123, 2020 (January)


2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Chi-Hua Yen ◽  
Shu-Ju Chen ◽  
Jen-Tzu Liu ◽  
Yu-Fen Tseng ◽  
Ping-Ting Lin

This study was aimed to investigate the effects of water extracts ofGraptopetalum paraguayense(WGP, 4 g/d) on blood pressure, blood glucose level, and lipid profiles in subjects with metabolic syndrome (MS). Participants with MS (n=54) were randomly assigned to the placebo (n=28) and WGP groups (n=26), and the intervention was administered for 12 weeks. Systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting glucose (FG), lipid profiles (total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and high density lipoprotein (HDL-C)), and antioxidant enzymes activities (catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx)) were measured. Forty-two subjects completed the study (placebo,n=19; WGP,n=23). FG, SBP, and LDL-C levels were significantly lower and HDL-C level and antioxidant enzymes activities (CAT and SOD) were significantly higher after WGP supplementation. Blood pressure, FG, and lipid profiles were significantly correlated with antioxidant enzymes activities after supplementation (P<0.05). The present study demonstrated a significant reduction in blood pressure, blood glucose, and lipid profiles and an increase in antioxidant enzymes activities in subjects with MS after WGP supplementation. Taken together, the antioxidative capacity of WGP might exert a beneficial effect on MS. This trial is registered with ClinicalTrials.govNCT01463748.


2020 ◽  
Vol 49 (4) ◽  
pp. 997-1002
Author(s):  
Shukanta Saha ◽  
Hasna Hena Begum ◽  
Shamima Nasrin ◽  
Rifat Samad

Drought stress caused the decrease of pigment contents - chlorophyll a, chlorophyll b, chlorophyll a/b ratio, total chlorophyll content and carotenoids content of leaves of five rice varieties (var. BRRI Dhan-30, BRRI Dhan-32, BRRI Dhan-34, BRRI Dhan-38 and BRRI Dhan-56). Among five rice varieties, BRRI Dhan- 56 showed the least decrease of pigment content under stress. It caused the decrease of protein content of leaves of five rice varieties whereas BRRI Dhan-56 showed the least decrease (3.64%) of protein content under stress. On the other hand, drought stress increased CAT and SOD activities in the leaf of five varieties of rice and BRRI Dhan-56 showed the highest increase of CAT (37.67%) and SOD (94.17%) activity under stress. It may be assumed that higher antioxidant enzymes activities (CAT and SOD) and less reduction of protein content were related to the mechanisms of drought tolerance in rice. It is indicated that BRRI Dhan- 56 may be drought tolerant while BRRI Dhan-30, BRRI Dhan-32, BRRI Dhan-34 and BRRI Dhan-38 were drought sensitive rice varieties. Drought tolerant rice variety is selected based on pigment content, protein content and antioxidant enzymes activities (CAT and SOD).


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Bor-Jen Lee ◽  
Yi-Chin Lin ◽  
Yi-Chia Huang ◽  
Ya-Wen Ko ◽  
Simon Hsia ◽  
...  

A higher oxidative stress may contribute to the pathogenesis of coronary artery disease (CAD). The purpose of this study was to investigate the relationship between coenzyme Q10 concentration and lipid peroxidation, antioxidant enzymes activities and the risk of CAD. Patients who were identified by cardiac catheterization as having at least 50% stenosis of one major coronary artery were assigned to the case group (n=51). The control group (n=102) comprised healthy individuals with normal blood biochemical values. The plasma coenzyme Q10, malondialdehyde (MDA) and antioxidant enzymes activities (catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx)) were measured. Subjects with CAD had significant lower plasma coenzyme Q10, CAT and GPx activities and higher MDA and SOD levels compared to those of the control group. The plasma coenzyme Q10 was positively correlated with CAT and GPx activities and negatively correlated with MDA and SOD. However, the correlations were not significant after adjusting for the potential confounders of CAD with the exception of SOD. A higher level of plasma coenzyme Q10 (≥0.52 μmol/L) was significantly associated with reducing the risk of CAD. Our results support the potential cardioprotective impact of coenzyme Q10.


2009 ◽  
Vol 33 (4) ◽  
pp. 717-725 ◽  
Author(s):  
Qing-Shun ZHANG ◽  
Jian-Jun HOU ◽  
Xiang-Jiang LIU ◽  
Jie-Xuan LUO ◽  
Bang-Xi XIONG

2013 ◽  
Vol 19 (3) ◽  
pp. 353-361 ◽  
Author(s):  
Jyoti R. Rout ◽  
Shidharth S. Ram ◽  
Ritarani Das ◽  
Anindita Chakraborty ◽  
Mathummal Sudarshan ◽  
...  

2018 ◽  
Vol 4 (5) ◽  
pp. 182-192 ◽  
Author(s):  
Fabiana B. de MOURA ◽  
Marcos R. da S. VIEIRA ◽  
Adriano do N. SIMÕES ◽  
Sérgio L. FERREIRA-SILVA ◽  
Carlos A.V. de SOUZA ◽  
...  

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