scholarly journals Effect of Capacitive Radiofrequency on the Fibrosis of Patients with Cellulite

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Rodrigo Marcel Valentim da Silva ◽  
Priscila Arend Barichello ◽  
Melyssa Lima Medeiros ◽  
Waléria Cristina Miranda de Mendonça ◽  
Jung Siung Camel Dantas ◽  
...  
Keyword(s):  
Blood Circulation ◽  
Collagen Fiber ◽  
Structural Changes ◽  
Active Electrode ◽  
Septal Thickness ◽  
Subcutaneous Adipose ◽  
Consequent Improvement ◽  
Degree Of Severity ◽  
Fiber Thickness ◽  
Collagen Tissue

Background. Cellulite is a type of lipodystrophy that develops primarily from an alteration in blood circulation or of the lymphatic system that causes structural changes in subcutaneous adipose tissue, collagen, and adjacent proteoglycans. The radiofrequency devices used for cutaneous applications have shown different physiological treatment effects, but there is controversy about the suitable parameters for this type of treatment.Objectives. The aim of this study was to evaluate the effects of low-temperature radiofrequency to confirm the thinning of the collagen tissue and interlobular septa and consequent improvement of cellulite.Methods. A sample of eight women was used to collect ultrasonographic data with a 12 MHz probe that measured collagen fiber thickness. The Vip Electromedicina (Argentina) device, frequency of 0.55 MHz and active electrode 3.5 cm in diameter (area = 9.61 cm2), was applied to a 10 cm2region of the gluteal region for 2 minutes per area of active electrode, during 10 biweekly sessions.Results. The Wilcoxon matched paired test was applied using GraphPad InStat 3.01 for Win95-NT software. Pre- and posttreatment mean collagen fiber thickness showed a 24.66% reduction from 1.01 to 0.67 mm. Statistical analysis using the Wilcoxon matched paired test obtained a significant two-tailedPvalue of 0.0391.Conclusion. It was concluded that the use of more comfortable temperatures favored a reduction in fibrous septum thickness and consequent cellulite improvement, evidenced by the lower degree of severity and decrease in interlobular septal thickness.

Structural Changes in Children’s Brain with Traumatic Brain Injury of Different Degree of Severity

2019 ◽  
Vol 4 (5) ◽  
pp. 173-179
Author(s):  
V. N. Petrenko ◽  
◽  
T. M. Prihodko ◽  
M. V. Hekova ◽  
V. V. Shevchenko
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Structural Changes ◽  
Degree Of Severity

scholarly journals On the Beneficial Effect of MgCl2 as Electrolyte Additive to Improve the Electrochemical Performance of Li4Ti5O12 as Cathode in Mg Batteries

Nanomaterials ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 484 ◽  
Author(s):  
Marta Cabello ◽  
Gregorio Ortiz ◽  
Pedro Lavela ◽  
José Tirado
Keyword(s):  
Electrochemical Performance ◽  
Structural Changes ◽  
Surface Film ◽  
Practical Importance ◽  
Specific Capacity ◽  
Ex Situ ◽  
Insertion Reaction ◽  
Portable Devices ◽  
Active Electrode ◽  
X Ray

Magnesium batteries are a promising technology for a new generation of energy storage for portable devices. Attention should be paid to electrolyte and electrode material development in order to develop rechargeable Mg batteries. In this study, we report the use of the spinel lithium titanate or Li4Ti5O12 (LTO) as an active electrode for Mg2+-ion batteries. The theoretical capacity of LTO is 175 mA h g−1, which is equivalent to an insertion reaction with 1.5 Mg2+ ions. The ability to enhance the specific capacity of LTO is of practical importance. We have observed that it is possible to increase the capacity up to 290 mA h g−1 in first discharge, which corresponds to the reaction with 2.5 Mg2+ ions. The addition of MgCl2·6H2O to the electrolyte solutions significantly improves their electrochemical performance and enables reversible Mg deposition. Ex-situ X-ray diffraction (XRD) patterns reveal little structural changes, while X-ray photoelectron spectrometer (XPS) (XPS) measurements suggest Mg reacts with LTO. The Ti3+/Ti4+ ratio increases with the amount of inserted magnesium. The impedance spectra show the presence of a semicircle at medium-low frequencies, ascribable to Mg2+ ion diffusion between the surface film and LTO. Further experimental improvements with exhaustive control of electrodes and electrolytes are necessary to develop the Mg battery with practical application.

scholarly journals Condition of the mother–placenta–fetal system in pregnant women with a general gynecological anamnesis

2021 ◽  
Vol 1 ◽  
pp. 70-74
Author(s):  
T. P. Andriichuk ◽  
A.Ya.  Senchuk ◽  
V.I. Chermak
Keyword(s):  
Pregnant Women ◽  
Blood Circulation ◽  
Control Group ◽  
Comprehensive Treatment ◽  
Perinatal Morbidity ◽  
Fetal Circulation ◽  
Fetoplacental Complex ◽  
Prophylactic Measures ◽  
Increased Risk ◽  
Degree Of Severity

The objective: based on the results of cardiotocographic (CTG) and ultrasound methods to determine the features of the fetoplacental complex (FPC) in pregnant women with a burdensome gynecological anamnesis.Materials and methods. 150 patients at 37–41 weeks of gestation were examined. The main group includes 100 pregnant women with chronic salpingo-ophoritis, the control group – 50 healthy pregnant women of the physiological obstetrics department. CTG monitoring of the fetus, ultrasound feto- and placentography, Doppler uterine-placental-fetal blood circulation were used to assess the state of FPC in pregnant women.Results. Analysis of fetal CTG and hemodynamic parameters in the uterine artery and umbilical vessels in pregnant women with chronic salpingo-ophoritis suggests that the course of pregnancy on the background of chronic salpingo-ophoritis in the mother is a factor that adversely affects the fetus and requires active pregnancy. Carrying out treatment-and-prophylactic measures for the purpose of improvement of perinatal results. The combination of unfavorable results of the examination by these methods, as well as adverse results after the usual comprehensive treatment in pregnancy 37–42 weeks is, in our opinion, an indication for emergency delivery according to the indications of the fetus.Conclusion. Identified disorders of uteroplacental and placental-fetal circulation should be regarded as those that correspond to the first degree of severity (disorders of uteroplacental with preservation of placental-fetal circulation). The results indicate the need to include women with chronic salpingo-ophoritis in the group of increased risk of placental dysfunction (PD) in order to prevent it in a timely manner, thereby reducing perinatal morbidity and mortality.

scholarly journals Blood circulation in the lungs: radiologic methods of diagnosing microcirculation changes in the small circle of circulation

2019 ◽  
Vol 18 (1) ◽  
pp. 5-16
Author(s):  
V. I. Amosov ◽  
V. Р. Zolotnitskaia
Keyword(s):  
Blood Circulation ◽  
Lung Diseases ◽  
Structural Changes ◽  
Lung Parenchyma ◽  
Pathological Process ◽  
Anatomical Structures ◽  
Small Circle ◽  
Anatomical Characteristic ◽  
History Of ◽  
Capillary Bed

Radiological diagnosis of diseases of the respiratory system includes a number of methods based on various ways of obtaining information about the state of the chest organs. Most of the applied methods are aimed at identifying structural changes in the lung parenchyma, however, with the development of lung diseases, the pathological process affects all anatomical structures of the lungs, without exception, including the vascular bed of the lungs, primarily due to its microcirculatory level, therefore, this process requires special attention of specialists to the methods detecting changes in the pulmonary microvasculature. Depending on the purposes of the study, various methods of radiologic diagnosis should be used in combination. The review provides a brief anatomical characteristic of the capillary bed of the lungs. History of the study of blood circulation in a small circle is discussed, and modern methods of radiologic research are used to detect lung diseases.

scholarly journals Influence of silver carp skins processing conditions on collagen structure

2020 ◽  
Vol 81 (4) ◽  
pp. 53-57
Author(s):  
L. V. Antipova ◽  
I. V. Sukhov ◽  
I. I. Kotov
Keyword(s):  
Collagen Fiber ◽  
Structural Changes ◽  
Silver Carp ◽  
Aggressive Medium ◽  
Comparative Characteristic ◽  
Native Structure ◽  
Initial Sample ◽  
Light Passing ◽  
Collagen Molecules ◽  
Selection Of

Infrared (IR) spectroscopy is currently one of the main methods for the analysis and identification of organic compounds. The method is based on passing infrared radiation through the object under study, which entails the excitation of molecules, forcing them to make oscillatory movements. During this process, a decrease in the intensity of light passing through the sample is observed. Absorption occurs at long waves, the energy of which is comparable with the excitation energy of vibrations in the molecules under study. This indicates the presence in the molecules of samples or functional groups. Thus, you can predict and find out about the possible structure of the substance. The authors of the study proposed a method for producing a collagen-containing base. The selection of the concentration of organic acid makes it possible to obtain a product with the necessary characteristics. The main objective of the experiment is to characterize the structural changes in the collagen fiber in the process of obtaining collagen hydrate. Infrared spectra were obtained at each stage, starting from the initial sample and ending with the final collagen hydrate. A comparative characteristic of the collagen molecules of the initial and final samples allows us to conclude that the aggressive medium in the process of hydrate production does not in the least damage the native structure of collagen fibrils. In the process of obtaining collagen fibers, they are released. Subsequently, the collagen bases were homogenized in a medium with distilled water, using the ratio: one part of the mass of processed silver carp skins and three parts of water. Obtaining an emulsion with high hydrophilicity, which creates the conditions for use in various forms in the food, cosmetic and medical industries.

scholarly journals Imaging Collagen Alterations in STICs and High Grade Ovarian Cancers in the Fallopian Tubes by Second Harmonic Generation Microscopy

Cancers ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 1805 ◽  
Author(s):  
Eric C. Rentchler ◽  
Kristal L. Gant ◽  
Ronny Drapkin ◽  
Manish Patankar ◽  
Paul J. Campagnola
Keyword(s):  
Second Harmonic Generation ◽  
Harmonic Generation ◽  
Collagen Fiber ◽  
Structural Changes ◽  
Second Harmonic ◽  
High Grade ◽  
Fallopian Tubes ◽  
Fiber Morphology ◽  
Ovarian Cancers ◽  
Insight Into

The majority of high-grade serous ovarian cancers originate in the fallopian tubes, however, the corresponding structural changes in the extracellular matrix (ECM) have not been well-characterized. This information could provide new insight into the carcinogenesis and provide the basis for new diagnostic tools. We have previously used the collagen-specific Second Harmonic Generation (SHG) microscopy to probe collagen fiber alterations in high-grade serous ovarian cancer and in other ovarian tumors, and showed they could be uniquely identified by machine learning approaches. Here we couple SHG imaging of serous tubal intra-epithelial carcinomas (STICs), high-grade cancers, and normal regions of the fallopian tubes, using three distinct image analysis approaches to form a classification scheme based on the respective collagen fiber morphology. Using a linear discriminant analysis, we achieved near 100% classification accuracy between high-grade disease and the other tissues, where the STICs and normal regions were differentiated with ~75% accuracy. Importantly, the collagen in high-grade disease in both the fallopian tube and the ovary itself have a similar collagen morphology, further substantiating the metastasis between these sites. This analysis provides a new method of classification, but also quantifies the structural changes in the disease, which may provide new insight into metastasis.

Exogenous vitamin C triggered structural changes of redox-activated dual core-crosslinked biodegradable nanogels for boosting the antitumor efficiency

2020 ◽  
Vol 8 (23) ◽  
pp. 5109-5116 ◽  
Author(s):  
Yutong Zhu ◽  
Yanmei He ◽  
Ting Su ◽  
Congrui Li ◽  
Shensheng Cai ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Vitamin C ◽  
Blood Circulation ◽  
Structural Changes ◽  
Tumor Site ◽  
Dual Core

Premature leakage of drugs during blood circulation and slow drug release at the tumor site are two major challenges that nanocarriers have to overcome to achieve successful cancer therapy.

scholarly journals Tensile Mechanical Properties and Dynamic Collagen Fiber Re-Alignment of the Murine Cervix Are Dramatically Altered Throughout Pregnancy

2017 ◽  
Vol 139 (6) ◽  
Author(s):  
Carrie E. Barnum ◽  
Jennifer L. Fey ◽  
Stephanie N. Weiss ◽  
Guillermo Barila ◽  
Amy G. Brown ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Preterm Birth ◽  
Material Properties ◽  
Time Course ◽  
Collagen Fiber ◽  
Structural Changes ◽  
Tensile Load ◽  
Primary Objective ◽  
Spontaneous Preterm Birth

The cervix is a unique organ able to dramatically change its shape and function by serving as a physical barrier for the growing fetus and then undergoing dramatic dilation allowing for delivery of a term infant. As a result, the cervix endures changing mechanical forces from the growing fetus. There is an emerging concept that the cervix may change or remodel “early” in many cases of spontaneous preterm birth (sPTB). However, the mechanical role of the cervix in both normal and preterm birth remains unclear. Therefore, the primary objective of this study was to determine the mechanical and structural responses of murine cervical tissue throughout a normal gestational time course. In this study, both tissue structural and material properties were determined via a quasi-static tensile load-to-failure test, while simultaneously obtaining dynamic collagen fiber re-alignment via cross-polarization imaging. This study demonstrated that the majority of the mechanical properties evaluated decreased at midgestation and not just at term, while collagen fiber re-alignment occurred earlier in the loading curve for cervices at term. This suggests that although structural changes in the cervix occur throughout gestation, the differences in material properties function in combination with collagen fiber re-alignment as mechanical precursors to regulate term gestation. This work lays a foundation for investigating cervical biomechanics and the role of the cervix in preterm birth.

FTIR imaging of structural changes in visceral and subcutaneous adiposity and brown to white adipocyte transdifferentiation

The Analyst ◽  
2015 ◽  
Vol 140 (7) ◽  
pp. 2205-2214 ◽  
Author(s):  
Fatma Kucuk Baloglu ◽  
Sebnem Garip ◽  
Sebastian Heise ◽  
Gudrun Brockmann ◽  
Feride Severcan
Keyword(s):  
Structural Changes ◽  
Obese Mice ◽  
Adipose Tissues ◽  
Ftir Imaging ◽  
White Adipocyte ◽  
Molecular Alterations ◽  
Ftir Microspectroscopy ◽  
Immunohistological Staining ◽  
Subcutaneous Adiposity ◽  
Subcutaneous Adipose

FTIR microspectroscopy coupled with UCP1 immunohistological staining enables the detection of obesity-related molecular alterations and transdifferentiations in visceral and subcutaneous adipose tissues in spontaneously obese mice lines.

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