scholarly journals Management of Locally Advanced Renal Cell Carcinoma with Invasion of the Duodenum

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Andrew T. Schlussel ◽  
Aaron B. Fowler ◽  
Herbert K. Chinn ◽  
Linda L. Wong
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Inferior Vena ◽  
Locally Advanced ◽  
Vena Cava ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc

Renal cell carcinoma (RCC) is rare but aggressive, with greater than 20% of patients presenting with stage III or IV, disease. Surgical resection of the primary tumor regardless of stage is the treatment of choice, and en bloc resection of involved organs provides the only potential chance for cure. This case report describes a patient with metastatic right-sided RCC with invasion of the inferior vena cava and duodenum managed by en block resection and pancreaticoduodenectomy. This report will review the workup and treatment of locally advanced RCC, as well as the role of cytoreductive nephrectomy in the setting of metastatic disease.

scholarly journals Role of presurgical targeted molecular therapy in renal cell carcinoma with an inferior vena cava tumor thrombus

2018 ◽  
Vol Volume 11 ◽  
pp. 1997-2005 ◽  
Author(s):  
Cheng Peng ◽  
Liangyou Gu ◽  
Lei Wang ◽  
Qingbo Huang ◽  
Baojun Wang ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Inferior Vena Cava ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Tumor Thrombus ◽  
Inferior Vena ◽  
Vena Cava ◽  
Molecular Therapy ◽  
Targeted Molecular Therapy

Survival and prognostic factors of patients who underwent total en bloc resection of spinal metastasis from renal cell carcinoma.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. e15548-e15548
Author(s):  
Satoshi Kato ◽  
Hideki Murakami ◽  
Satoru Demura ◽  
Katsuhito Yoshioka ◽  
Hiroyuki Hayashi ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Spinal Metastasis ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc

Tumors at the Aortoiliac/Inferior Vena Cava Bifurcation: Preoperative, Anesthetic, and Intraoperative Considerations

2007 ◽  
Vol 73 (5) ◽  
pp. 440-446
Author(s):  
James R. Ouellette ◽  
David V. Cossman ◽  
Karen S. Sibert ◽  
Nicholas P. Mcandrew ◽  
Allan W. Silberman
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Preoperative Planning ◽  
Locally Advanced ◽  
Vena Cava ◽  
Surgical Oncology ◽  
En Bloc ◽  
Retroperitoneal Tumors ◽  
Vascular Structures

Primary and recurrent retroperitoneal tumors can involve the aortoiliac vasculature. They are often considered inoperable or incurable because of the locally advanced nature of the disease or the technical aspects involved in safely resecting the lesion. Safe resection of these lesions requires experience and extensive preoperative planning for success. A retrospective database review of 76 patients with retroperitoneal tumors identified tumors involving major vascular structures in the abdomen and pelvis undergoing resection of tumor en bloc with the aortoiliac vasculature. Preoperative planning and intraoperative technical maneuvers are reviewed. Patients were followed until time of this report. Four patients with retroperitoneal tumors involving the aortoiliac vessels underwent surgery: two patients with sarcoma (one primary and one recurrent), one with metastatic renal cell carcinoma, and one with a paraganglioma. All patients had resection of the aorta and vena cava or the iliac artery and vein. Arterial reconstruction (anatomic or extra-anatomic) was performed in all cases. The patient with renal cell carcinoma also required venous reconstruction to support a renal autotransplant. Veno-venous bypass was required in one patient. Local control was achieved in 3 of 4 cases. Surgery for retroperitoneal tumors involving major vascular structures is technically feasible with appropriate planning and technique. Multiple disciplines are required, including general surgical oncology, vascular surgery, and possibly, cardiothoracic surgery.

scholarly journals Solitary spinal metastasis of renal cell carcinoma and en-bloc resection-A case report

2020 ◽  
Vol 1 (1) ◽  
pp. 29-32
Author(s):  
Balgopal Karmacharya ◽  
Nikunja Yogi ◽  
Aabishkar Bhattarai ◽  
Anjali Bhandari ◽  
Prabin Bhandari ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Spinal Metastasis ◽  
Poor Response ◽  
En Bloc Resection ◽  
Metastatic Lesion ◽  
Bloc Resection ◽  
Pedicle Screw Fixation ◽  
En Bloc

Renal Cell Carcinoma is a challenging condition for clinicians because of its poor response to radiotherapy, chemotherapy and even immunotherapy. Spine is the second most common site of metastasis and is also an indicator of poor prognosis. There is a significant dilemma for brain and spine surgeons about when to undergo aggressive surgical treatment, such as en-bloc resection of oligo-spine metastasis compared to conventional tumor excision by curettage. Here, we report a case of 60-year old female, a diagnosed case of renal cell carcinoma who had undergone right sided nephrectomy (with adrenalectomy) 5 years ago. She presented with history of pain over upper back. MRI revealed metastatic lesion over the thoracic T-7 vertebra. She underwent en-block total vertebral resection and reconstruction with titanium cage and pedicle screw fixation of the T-7 vertebra which healed with good results.

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