scholarly journals Epidemiology of Thyroid Cancer in an Area of Epidemic Thyroid Goiter

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Antonio Cossu ◽  
Mario Budroni ◽  
Panagiotis Paliogiannis ◽  
Giuseppe Palmieri ◽  
Fabrizio Scognamillo ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Local Tumor ◽  
Tumor Registry ◽  
High Incidence ◽  
Increasing Trend ◽  
Thyroid Goiter ◽  
Epidemiological Characteristics ◽  
Tumor Registries ◽  
Economic And Social Impacts ◽  
Overall Mortality

The aim of this study was to analyze and describe the epidemiological characteristics and trends of thyroid cancer in the province of Sassari (Sardinia, Italy), an area with epidemic thyroid goiter, in the period 1992–2010. Data were obtained from the local tumor registry which makes part of a wider registry web, coordinated today by the Italian Association for Tumor Registries. An increasing trend in the incidence of thyroid cancer in the province of Sassari was evidenced. This trend seems to follow the general worldwide trend and does not seem to be related to the high incidence of thyroid goiter in the area. The frequencies of the different histological subtypes were similar to those reported in numerous national and international reports. Women are affected earlier than men and, therefore, suffer greater professional, economic, and social impacts. Overall mortality is low and a relative 5-year survival is excellent, especially in comparison to other malignancies.

scholarly journals Epidemiological Characteristics of Severe Fever with Thrombocytopenia Syndrome from 2010 to 2019 in Mainland China

2021 ◽  
Vol 18 (6) ◽  
pp. 3092
Author(s):  
Xiaoxia Huang ◽  
Jiandong Li ◽  
Aqian Li ◽  
Shiwen Wang ◽  
Dexin Li
Keyword(s):  
Statistical Significance ◽  
Regional Distribution ◽  
Mainland China ◽  
Deep Understanding ◽  
Scientific Data ◽  
High Risk Population ◽  
Middle Aged ◽  
Increasing Trend ◽  
Epidemiological Characteristics ◽  
Severe Fever

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that is a severe threat to public health considering its high fatality and person-to-person transmission. In order to obtain an updated and deep understanding of the epidemiological characteristics of SFTS in mainland China, we used Pearson’s chi-squared test to compare the fatality rate and demographic characteristics in different groups. Data were analyzed in R3.6.1 (R Development Core Team 2018), while the visualization was performed in ArcGIS 10 (ESRI, Redlands, CA, USA), and the statistical significance was set at p < 0.05. A total of 13,824 SFTS cases involving 8899 lab-confirmed cases and 4925 probable cases were reported and included in the epidemiological analysis. Our study found that the number of SFTS cases showed an increasing trend with a small decrease in the past three years. The laboratory-confirmed rate was about 64.4%, which varied between different years and areas. Although most cases (99.3%) were distributed in 7 provinces (Henan, Shandong, Anhui, Hubei, Liaoning, Zhejiang, and Jiangsu), the regional distribution of SFTS gradually expanded from 5 provinces in 2010 to 25 provinces by 2019, especially at the town level. The SFTS cases were mainly sporadic. A total of 96.5% occurred from April to October, and 93.3% of cases were concentrated in middle-aged and elderly people (40–84 years old). Farmers were the main high-risk population. Female cases were slightly more than male cases; however, there were differences between different provinces. The mortality rate showed an increasing trend with age. Overall, the SFTS cases were mainly middle-aged and elderly farmers that sporadically distributed throughout seven provinces with a spatially expanding trend. The laboratory-confirmed rate varied in different years and provinces, which implied that the diagnosis and report criteria for SFTS should be further updated and unified in order to get a better understanding of its epidemiological characteristics and provide scientific data for SFTS control.

scholarly journals THE CHANGING TREND OF MORTALITY CAUSED BY GASTROINTESTINAL CANCERS IN IRAN DURING THE YEARS 2006-2010

2018 ◽  
Vol 55 (3) ◽  
pp. 237-241 ◽  
Author(s):  
Fatemeh SALEHI ◽  
Ali AHMADI ◽  
Seyede Soghra AHMADI SOODEJANI ◽  
Milad SHAHINI SHAMS ABADI
Keyword(s):  
Causes Of Death ◽  
Age Groups ◽  
Mortality Data ◽  
Gastrointestinal Cancers ◽  
Mortality Trend ◽  
Pancreatic Cancers ◽  
Incidence And Mortality ◽  
High Incidence ◽  
Increasing Trend ◽  
Changing Trend

ABSTRACT BACKGROUND: Cancers are one of the most important causes of death in the world. According to their high incidence and mortality, gastrointestinal cancers have particular importance among other cancers. OBJECTIVE: Therefore, this study was conducted to investigate the mortality change trends of gastrointestinal cancers in Iran. METHODS: This study was performed by analyzing the reported mortality data in 29 provinces of Iran in 2006-2010. Mortality trend of gastrointestinal cancers was drawn for both sexes in the study years and disaggregated by age groups and their frequency distribution. The WinPepi software was used for analysis. RESULTS: In the years 2006-2010, the mortality rate of, gastric, colorectal, liver and pancreatic cancers, has significantly increased. Totally, gastrointestinal mortality is higher in men than women. Also, the results showed that by increasing age, death from these cancers also increased. CONCLUSION: The most important causes of death from gastrointestinal cancers were gastric, liver and colorectal cancers in Iran and because of their increasing trend in the country, performing preventive interventions for the cancers’ risk factors is necessary.

scholarly journals Epidemiological Characteristics and Spatiotemporal Analysis of Mumps from 2004 to 2018 in Chongqing, China

2019 ◽  
Vol 16 (17) ◽  
pp. 3052 ◽  
Author(s):  
Zhu ◽  
Zhao ◽  
Ou ◽  
Xiang ◽  
Hu ◽  
...  
Keyword(s):  
Public Health ◽  
Spatial Autocorrelation ◽  
Descriptive Analysis ◽  
Health Resources ◽  
Public Health Problem ◽  
Risk Groups ◽  
Scan Statistics ◽  
Time Space ◽  
High Incidence ◽  
Epidemiological Characteristics

Mumps vaccines have been widely used in recent years, but frequent mumps outbreaks and re-emergence around the world have not stopped. Mumps still remains a serious public health problem with a high incidence in China. The status of mumps epidemics in Chongqing, the largest city in China, is still unclear. This study aimed to investigate the epidemiological and spatiotemporal characteristics of mumps and to provide a scientific basis for formulating effective strategies for its prevention and control. Surveillance data of mumps in Chongqing from January 2004 to December 2018 were collected from the National Notifiable Diseases Reporting Information System. A descriptive analysis was conducted to understand the epidemiological characteristics. Hot spots and spatiotemporal patterns were identified by performing a spatial autocorrelation analysis, a purely spatial scan, and a spatiotemporal scan at the county level based on geographic information systems. A total of 895,429 mumps cases were reported in Chongqing, with an annual average incidence of 36.34 per 100,000. The yearly incidence of mumps decreased markedly from 2004 to 2007, increased sharply from 2007 to 2011, and then tapered with a two-year cyclical peak after 2011. The onset of mumps showed an obvious bimodal seasonal distribution, with a higher peak of mumps observed from April to July of each year. Children aged 5–9 years old, males, and students were the prime high-risk groups. The spatial distribution of mumps did not exhibit significant global autocorrelation in most years, but local indicators of spatial autocorrelation and scan statistics detected high-incidence clusters which were mainly located in the midwestern, western, northeastern, and southwestern parts of Chongqing. The aggregation time frame detected by the purely temporal scan was between March 2009 and July 2013. The incidence of mumps in Chongqing from 2004 to 2018 featured significant spatial heterogeneity and spatiotemporal clustering. The findings of this study might assist public health agencies to develop real-time space monitoring, especially in the clustering regions and at peak periods; to improve immunization strategies for long-term prevention; and to deploy health resources reasonably.

scholarly journals Etiologic Spectrum of Intestinal Obstruction in Ningxia District: A Retrospective Analysis of 4908 Cases in a 10-Year Period

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Wei Jiang ◽  
Wenyan Li ◽  
Qian Hao ◽  
Yuping Yao ◽  
Yajun Li ◽  
...  
Keyword(s):  
Intestinal Obstruction ◽  
Bowel Obstruction ◽  
Clinical Manifestations ◽  
Therapeutic Interventions ◽  
Malignant Bowel Obstruction ◽  
Increasing Trend ◽  
Adhesive Intestinal Obstruction ◽  
Adhesive Obstruction ◽  
Medical University ◽  
Overall Mortality

Background. Economic disparity contributes to the variation of intestinal obstruction (IO) etiologic spectrum. Clarifying the etiology distribution in local regions can help to unravel IO and promote early diagnosis, henceforth making sure standardized therapeutic interventions. Methods. Medical data of 4908 inpatients diagnosed with IO admitted to the General Hospital of Ningxia Medical University between January 2004 and December 2013 were recruited and analyzed retrospectively. The associated profiles included demographic features, clinical manifestations, and previous therapeutic operations. Results. 4908 cases of intestinal obstruction were identified during the period of study. It denoted that the hospitalization rate of IO has maintained upward momentum; the top four causes of IO were adhesion, tumor, intussusception, and hernias. These covered up nearly 80% of the total constitution. Among them, adhesive intestinal obstruction accounted for 45.17%, malignant bowel obstruction for 21.09%, intussusception for 8.72%, and hernia for 4.73%; abdominal surgery constituted for the majority (78.62%) of adhesive obstruction. The followed up analysis also found that appendectomy accounted for the biggest percentage, 28% of operation cases. Malignant bowel obstruction can have a rate of 96.43% in 1035 cases led by tumor lesions. Of which, the primary intestinal malignant tumor accounted for 68.64% and metastatic tumors for 31.36%. Nearly 50% occurred in the large intestine. The overall mortality of all 4908 cases was 4.7%. Conclusion. The hospitalizations of IO delineated an increasing trend. Adhesion was the main etiology in IO. The odds of malignant bowel obstruction was increasing in the proportion of IO. There were some differences towards the etiologic spectrum compared with western countries.

scholarly journals Epidemiology of Simultaneous Medullary and Papillary Thyroid Carcinomas (MTC/PTC): An Italian Multicenter Study

Cancers ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 1516 ◽  
Author(s):  
Marialuisa Appetecchia ◽  
Rosa Lauretta ◽  
Agnese Barnabei ◽  
Letizia Pieruzzi ◽  
Irene Terrenato ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Clinical Outcome ◽  
Stage Iv ◽  
Papillary Thyroid ◽  
Time To Progression ◽  
Cytological Examination ◽  
Multicentric Study ◽  
Epidemiological Characteristics ◽  
Disease Free

Background: The concomitant presence of papillary thyroid cancer (PTC) and medullary TC (MTC) is rare. In this multicentric study, we documented the epidemiological characteristics, disease conditions and clinical outcome of patients with simultaneous MTC/PTC. Methods: We collected data of patients with concomitant MTC/PTC at 14 Italian referral centers. Results: In total, 183 patients were enrolled. Diagnosis was mostly based on cytological examination (n = 58, 32%). At diagnosis, in the majority of cases, both PTC (n = 142, 78%) and MTC (n = 100, 54%) were at stage I. However, more cases of stage II–IV were reported with MTC (stage IV: n = 27, 15%) compared with PTC (n = 9, 5%). Information on survival was available for 165 patients: 109 patients (66%) were disease-free for both PTC and MTC at the last follow-up. Six patients died from MTC. Median time to progression was 123 months (95% confidence interval (CI): 89.3–156.7 months). Overall, 45% of patients were disease-free after >10 years from diagnosis (125 months); this figure was 72.5% for PTC and 51.1% for MTC. Conclusions: When MTC and PTC are concurrent, the priority should be given to the management of MTC since this entity appears associated with the most severe impact on prognosis.

scholarly journals Familial Nontoxic Multinodular Thyroid Goiter Locus Maps to Chromosome 14q but Does Not Account for Familial Nonmedullary Thyroid Cancer

1997 ◽  
Vol 61 (5) ◽  
pp. 1123-1130 ◽  
Author(s):  
Graham R. Bignell ◽  
Federico Canzian ◽  
Maryam Shayeghi ◽  
Markus Stark ◽  
Yin Y. Shugart ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Thyroid Goiter ◽  
Chromosome 14Q

Thyroid Cancer—Risks and Causes

2014 ◽  
Vol 10 (02) ◽  
pp. 144
Author(s):  
Simon Bonnefond ◽  
Terry F Davies ◽  
◽  
Keyword(s):  
Thyroid Cancer ◽  
Molecular Mechanisms ◽  
Kinase Inhibitors ◽  
Significant Proportion ◽  
Precipitating Factors ◽  
Local Tumor ◽  
Cancer Risks ◽  
The Us ◽  
Different Types ◽  
Metastatic Thyroid Cancer

The incidence of thyroid cancer has almost doubled in recent years and over 60,000 people will be diagnosed in the US in 2015. While the prognosis for most such patients is excellent, a significant proportion die of thyroid cancer from local tumor progression and above all from metastases. Here we review the different types of thyroid cancers and their molecular changes with a special emphasis on the currently known susceptibility and precipitating factors. With the recent clinical introduction of tyrosine kinase inhibitors for the treatment of metastatic thyroid cancer it is clear that a simple cure is not at hand and further understanding of the molecular mechanisms of these tumors is urgently needed.

X-RAY FLUORESCENCE ANALYSIS IN THE DIAGNOSIS OF THYROID CANCER

2017 ◽  
pp. 39-45
Author(s):  
В. Зайчик ◽  
V. Zaychik ◽  
Г. Давыдов ◽  
G. Davydov
Keyword(s):  
Thyroid Cancer ◽  
Normal Tissue ◽  
Thyroid Tissue ◽  
Nodular Goiter ◽  
Fluorescence Analysis ◽  
Fluorescence Excitation ◽  
X Ray ◽  
Thyroid Goiter ◽  
Diagnosis Of Thyroid Cancer

Purpose: To investigate new possibilities of differential diagnosis of benign and malignant thyroid goiter lesions by means of energy dispersive X-ray fluorescence analysis (EDRFA). Material and methods: In the samples of thyroid tissue taken from people with intact thyroid gland (mostly died from trauma, n = 92), as well as in patients with nodular goiter (n = 79) and thyroid cancer (n = 40) bromine (Br), copper (Cu), iron (Fe), iodine (I), rubidium (Rb) and strontium (Sr) were investigated. To determine these elements, the methods of EDRPA have been developed using encapsulated sources with 109Cd and 241Am radionuclides for fluorescence excitation. Results: It is shown that the levels of the content of I, the ratios I / Cu and I / Rb, as well as the products of the ratios I / Cu ∙ (I / Rb) and (I / Br) ∙ (I / Cu) ∙ (I / Rb ) are highly informative markers of thyroid cancer. The accuracy of the developed methods and the reliability of the results obtained were confirmed by measurements of international certified comparison materials. Conclusion: The use of the proposed markers allows in vitro to differentiat thyroid cancer from benign nodes and normal tissue with sensitivity in the range of 86–100 %, specificity of 89–99 %, and accuracy within 90–99 %.

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