scholarly journals Ontology-Oriented Diagnostic System for Traditional Chinese Medicine Based on Relation Refinement

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Peiqin Gu ◽  
Huajun Chen ◽  
Tong Yu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Medical Knowledge ◽  
Diagnostic System ◽  
Syndrome Differentiation ◽  
Diagnosis System ◽  
Knowledge Based ◽  
Interpretable Model ◽  
Online Web ◽  
Clinical Cases

Although Chinese medicine treatments have become popular recently, the complicated Chinese medical knowledge has made it difficult to be applied in computer-aided diagnostics. The ability to model and use the knowledge becomes an important issue. In this paper, we define the diagnosis in Traditional Chinese Medicine (TCM) as discovering the fuzzy relations between symptoms and syndromes. An Ontology-oriented Diagnosis System (ODS) is created to address the knowledge-based diagnosis based on a well-defined ontology of syndromes. The ontology transforms the implicit relationships among syndromes into a machine-interpretable model. The clinical data used for feature selection is collected from a national TCM research institute in China, which serves as a training source for syndrome differentiation. The ODS analyzes the clinical cases to obtain a statistical mapping relation between each syndrome and associated symptom set, before rechecking the completeness of related symptoms via ontology refinement. Our diagnostic system provides an online web interface to interact with users, so that users can perform self-diagnosis. We tested 12 common clinical cases on the diagnosis system, and it turned out that, given the agree metric, the system achieved better diagnostic accuracy compared to nonontology method—92% of the results fit perfectly with the experts’ expectations.

An Intuitionistic Fuzzy Set-Based Model for Intelligent Traditional Chinese Medicine Diagnosis

2011 ◽  
Vol 480-481 ◽  
pp. 944-949
Author(s):  
Mei Hong Wu
Keyword(s):  
Decision Making ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Fuzzy Set ◽  
Intuitionistic Fuzzy Set ◽  
Medical Knowledge ◽  
Syndrome Differentiation ◽  
New Approach ◽  
Intuitionistic Fuzzy ◽  
Fuzzy Match

According to the characteristics of Traditional Chinese Medicine, this paper introduces an intuitionistic fuzzy set-based method to realize the intelligent diagnostic decision making. We firstly concentrate on diagnosis of diseases and differentiation of syndromes by modeling medical diagnosis rules via intuitionistic fuzzy relations as well as how to obtain intuitionistic medical knowledge on the basis of intuitionistic fuzzy sets. Subsequently we develop a new approach to point out the final proper diagnosis by largest degree of intuitionistic cognitive fuzzy match between symptoms characteristic for a patient and symptoms indicate the considered illnesses in decision-making process. The new approach allows reaching the intelligent diagnoses reasonably and easily, which benefit TCM syndrome differentiation for the whole diagnosis.

scholarly journals Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging

2019 ◽  
Vol 47 (4) ◽  
pp. 1580-1591 ◽  
Author(s):  
Wei Cen ◽  
Ralph Hoppe ◽  
Aiwu Sun ◽  
Hongyan Ding ◽  
Ning Gu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Electrical Activity ◽  
Computer Modeling ◽  
Cardiac Electrophysiology ◽  
Three Dimensional ◽  
Mathematical Physics ◽  
Syndrome Differentiation ◽  
Physics Model ◽  
Machine Readable

Objectives The principal diagnostic methods of traditional Chinese medicine (TCM) are inspection, auscultation and olfaction, inquiry, and pulse-taking. Treatment by syndrome differentiation is likely to be subjective. This study was designed to provide a basic theory for TCM diagnosis and establish an objective means of evaluating the correctness of syndrome differentiation. Methods We herein provide the basic theory of TCM syndrome computer modeling based on a noninvasive cardiac electrophysiology imaging technique. Noninvasive cardiac electrophysiology imaging records the heart’s electrical activity from hundreds of electrodes on the patient’s torso surface and therefore provides much more information than 12-lead electrocardiography. Through mathematical reconstruction algorithm calculations, the reconstructed heart model is a machine-readable description of the underlying mathematical physics model that reveals the detailed three-dimensional (3D) electrophysiological activity of the heart. Results From part of the simulation results, the imaged 3D cardiac electrical source provides dynamic information regarding the heart’s electrical activity at any given location within the 3D myocardium. Conclusions This noninvasive cardiac electrophysiology imaging method is suitable for translating TCM syndromes into a computable format of the underlying mathematical physics model to offer TCM diagnosis evidence-based standards for ensuring correct evaluation and rigorous, scientific data for demonstrating its efficacy.

scholarly journals Treatment of Oral Ulcer Based on TCM Syndrome Differentiation

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Ying Yao ◽  
Li Liu
Keyword(s):  
Quality Of Life ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Western Medicine ◽  
Severe Case ◽  
Oral Ulcer ◽  
Syndrome Differentiation ◽  
Tcm Syndrome ◽  
Chinese Medicine Treatment

Oral ulcer is a kind of ulcerative injury that occurs in the oral mucosa and is very common in clinic. In severe case, it can affect the quality of life of the patients. Western medicine treatment of oral ulcer is often prone to relapse, while the effect of traditional Chinese medicine treatment is remarkable.

scholarly journals A Network-Based Systematic Study for the Mechanism of the Treatment of Zhengs Related to Cough Variant Asthma

2013 ◽  
Vol 2013 ◽  
pp. 1-15 ◽  
Author(s):  
Di Chen ◽  
Fangbo Zhang ◽  
Shihuan Tang ◽  
Yan Chen ◽  
Peng Lu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Airway Inflammation ◽  
Systematic Study ◽  
Steroid Metabolism ◽  
Cough Variant Asthma ◽  
Functional Annotations ◽  
Metabolism Regulation ◽  
Significant Efficacy ◽  
Clinical Cases

Traditional Chinese medicine (TCM) has shown significant efficacy in the treatment of cough variant asthma (CVA), a special type of asthma. However, there is shortage of explanations for relevant mechanism of treatment. As Zhengs differentiation is a critical concept in TCM, it is necessary to explain the mechanism of treatment of Zhengs. Based on TCM clinical cases, this study illustrated the mechanism of the treatment of three remarkably relevant Zhengs for CVA: “FengXieFanFei,” “FeiQiShiXuan”, and “QiDaoLuanJi.” To achieve this goal, five steps were carried out: (1) determining feature Zhengs and corresponding key herbs of CVA by analyses of clinical cases; (2) finding out potential targets of the key herbs and clustering them based on their functional annotations; (3) constructing an ingredient-herb network and an ingredient network; (4) identifying modules of the ingredient network; (5) illustrating the mechanism of the treatment by further mining the latent biological implications within each module. The systematic study reveals that the treatment of “FengXieFanFei,” “FeiQiShiXuan,” and “QiDaoLuanJi” has effects on the regulation of multiple bioprocesses by herbs containing different ingredients with functions of steroid metabolism regulation, airway inflammation, and ion conduction and transportation. This network-based systematic study will be a good way to boost the scientific understanding of mechanism of the treatment of Zhengs.

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