Univariate analysis of syndrome differentiation in traditional Chinese medicine and clinical correlative factors in gastric cancer

2007 ◽  
Vol 5 (4) ◽  
pp. 398-402 ◽  
Author(s):  
Li Tao
Keyword(s):  
Gastric Cancer ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Univariate Analysis ◽  
Syndrome Differentiation

scholarly journals Relationship betweenEGF,TGFA, andEGFRGene Polymorphisms and Traditional Chinese Medicine ZHENG in Gastric Cancer

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Junfeng Zhang ◽  
Zhen Zhan ◽  
Juan Wu ◽  
Chunbing Zhang ◽  
Yaping Yang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Blood Stasis ◽  
Syndrome Differentiation ◽  
Nucleotide Polymorphisms ◽  
Important Principle ◽  
Increased Risk ◽  
Genetic Mechanisms ◽  
Herbal Formulae

In traditional Chinese medicine (TCM), correct syndrome differentiation is the most important principle guiding the prescription of Chinese herbal formulae for the treatment of gastric cancer (GC). We aimed to reveal the genetic mechanisms underlying GC syndrome differentiation (ZHENG) in a population of 387 GC patients. Twenty-nine single nucleotide polymorphisms (SNPs) inEGF,TGFA, andEGFRwere investigated. Two SNPs, rs11466285 inTGFAand rs884225 inEGFR, were significantly associated with the distribution of ZHENG(P<0.05). The rs11466285 TT genotype increased the risk of damp heat with toxin (DHT) and deficiency of bothQiandyin(DQY) compared with obstruction of blood stasis (OBS). The rs884225 AA genotype could increase the risk of DQY and deficiency of bothQiand blood (DQB) compared withyindeficiency due to stomach heat (YDSH). Parallel comparison among the SNPs and syndrome types revealed that DQB was distinct from YDSH, disharmony between the liver and stomach, stagnation of phlegm muddiness (SPM), OBS, and other syndromes at several SNP loci(P<0.05). The rs11466285 TT and rs884225 AA genotypes exhibit increased risk of DQB compared with OBS and SPM(P<0.05), respectively. In conclusion, the formation of GC ZHENG was related toEGF,TGFA, andEGFRgene polymorphisms.

scholarly journals Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging

2019 ◽  
Vol 47 (4) ◽  
pp. 1580-1591 ◽  
Author(s):  
Wei Cen ◽  
Ralph Hoppe ◽  
Aiwu Sun ◽  
Hongyan Ding ◽  
Ning Gu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Electrical Activity ◽  
Computer Modeling ◽  
Cardiac Electrophysiology ◽  
Three Dimensional ◽  
Mathematical Physics ◽  
Syndrome Differentiation ◽  
Physics Model ◽  
Machine Readable

Objectives The principal diagnostic methods of traditional Chinese medicine (TCM) are inspection, auscultation and olfaction, inquiry, and pulse-taking. Treatment by syndrome differentiation is likely to be subjective. This study was designed to provide a basic theory for TCM diagnosis and establish an objective means of evaluating the correctness of syndrome differentiation. Methods We herein provide the basic theory of TCM syndrome computer modeling based on a noninvasive cardiac electrophysiology imaging technique. Noninvasive cardiac electrophysiology imaging records the heart’s electrical activity from hundreds of electrodes on the patient’s torso surface and therefore provides much more information than 12-lead electrocardiography. Through mathematical reconstruction algorithm calculations, the reconstructed heart model is a machine-readable description of the underlying mathematical physics model that reveals the detailed three-dimensional (3D) electrophysiological activity of the heart. Results From part of the simulation results, the imaged 3D cardiac electrical source provides dynamic information regarding the heart’s electrical activity at any given location within the 3D myocardium. Conclusions This noninvasive cardiac electrophysiology imaging method is suitable for translating TCM syndromes into a computable format of the underlying mathematical physics model to offer TCM diagnosis evidence-based standards for ensuring correct evaluation and rigorous, scientific data for demonstrating its efficacy.

scholarly journals Treatment of Oral Ulcer Based on TCM Syndrome Differentiation

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Ying Yao ◽  
Li Liu
Keyword(s):  
Quality Of Life ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Western Medicine ◽  
Severe Case ◽  
Oral Ulcer ◽  
Syndrome Differentiation ◽  
Tcm Syndrome ◽  
Chinese Medicine Treatment

Oral ulcer is a kind of ulcerative injury that occurs in the oral mucosa and is very common in clinic. In severe case, it can affect the quality of life of the patients. Western medicine treatment of oral ulcer is often prone to relapse, while the effect of traditional Chinese medicine treatment is remarkable.

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