scholarly journals Loranthus micranthusLinn.: Biological Activities and Phytochemistry

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Soheil Zorofchian Moghadamtousi ◽  
Maryam Hajrezaei ◽  
Habsah Abdul Kadir ◽  
Keivan Zandi
Keyword(s):  
Medicinal Plant ◽  
Mineral Nutrition ◽  
Current Knowledge ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Pharmacological Properties ◽  
Host Trees ◽  
Trees And Shrubs ◽  
Respective Host

Loranthus micranthusLinn. is a medicinal plant from the Loranthaceae family commonly known as an eastern Nigeria species of the African mistletoe and is widely used in folkloric medicine to cure various ailments and diseases. It is semiparasitic plant because of growing on various host trees and shrubs and absorbing mineral nutrition and water from respective host. Hence, the phytochemicals and biological activities ofL. micranthusdemonstrated strong host and harvesting period dependency. The leaves have been proved to possess immunomodulatory, antidiabetic, antimicrobial, antihypertensive, antioxidant, antidiarrhoeal, and hypolipidemic activities. This review summarizes the information and findings concerning the current knowledge on the biological activities, pharmacological properties, toxicity, and chemical constituents ofLoranthus micranthus.

scholarly journals Prunella vulgaris: A Comprehensive Review of Chemical Constituents, Pharmacological Effects and Clinical Applications

2019 ◽  
Vol 25 (3) ◽  
pp. 359-369 ◽  
Author(s):  
Su-Juan Wang ◽  
Xiao-He Wang ◽  
Yuan-Yuan Dai ◽  
Ming-Hua Ma ◽  
Khalid Rahman ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Current Knowledge ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Mechanisms Of Action ◽  
Clinical Applications ◽  
In Vivo Studies ◽  
Perennial Herb ◽  
Prunella Vulgaris

Prunella vulgaris (PV) is a perennial herb belonging to the Labiate family and is widely distributed in the northeastern Asian countries such as Korea, Japan, and China. It is reported to display diverse biological activities including anti-microbial, anti-cancer, and anti-inflammation as determined by in vitro or in vivo studies. So far, about 200 compounds have been isolated from PV plant and a majority of these have been characterized mainly as triterpenoids, sterols and flavonoids, followed by coumarins, phenylpropanoids, polysaccharides and volatile oils. This review summarizes and analyzes the current knowledge on the chemical constituents, pharmacological activities, mechanisms of action and clinical applications of the PV plant including its potential as a future medicinal plant. Although some of the chemical constituents of the PV plant and their mechanisms of action have been investigated, the biological activities of many of these remain unknown and further clinical trials are required to further enhance its reputation as a medicinal plant.

Tamarix articulata (T. articulata) - An Important Halophytic Medicinal Plant with Potential Pharmacological Properties

2019 ◽  
Vol 20 (4) ◽  
pp. 285-292 ◽  
Author(s):  
Abdullah M. Alnuqaydan ◽  
Bilal Rah
Keyword(s):  
Medicinal Plant ◽  
Biological Activities ◽  
Wide Spectrum ◽  
Biological Properties ◽  
In Vivo Model ◽  
Drug Candidate ◽  
Phytochemical Analysis ◽  
Pharmacological Properties

Background:Tamarix Articulata (T. articulata), commonly known as Tamarisk or Athal in Arabic region, belongs to the Tamaricaece species. It is an important halophytic medicinal plant and a good source of polyphenolic phytochemical(s). In traditional medicines, T. articulata extract is commonly used, either singly or in combination with other plant extracts against different ailments since ancient times.Methods:Electronic database survey via Pubmed, Google Scholar, Researchgate, Scopus and Science Direct were used to review the scientific inputs until October 2018, by searching appropriate keywords. Literature related to pharmacological activities of T. articulata, Tamarix species, phytochemical analysis of T. articulata, biological activities of T. articulata extracts. All of these terms were used to search the scientific literature associated with T. articulata; the dosage of extract, route of administration, extract type, and in-vitro and in-vivo model.Results:Numerous reports revealed that T. articulata contains a wide spectrum of phytochemical(s), which enables it to have a wide window of biological properties. Owing to the presence of high content of phytochemical compounds like polyphenolics and flavonoids, T. articulata is a potential source of antioxidant, anti-inflammatory and antiproliferative properties. In view of these pharmacological properties, T. articulata could be a potential drug candidate to treat various clinical conditions including cancer in the near future.Conclusion:In this review, the spectrum of phytochemical(s) has been summarized for their pharmacological properties and the mechanisms of action, and the possible potential therapeutic applications of this plant against various diseases discussed.

scholarly journals A Phytopharmacological Review on a Medicinal Plant: Cordia africana Lam.

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Gashaw Nigussie ◽  
Fozia Ibrahim ◽  
Sebsib Neway
Keyword(s):  
Medicinal Plant ◽  
Human Health ◽  
Soil Conservation ◽  
Therapeutic Potential ◽  
Future Research ◽  
Pharmacological Properties ◽  
Young Branch ◽  
Cordia Africana ◽  
Trees And Shrubs ◽  
Different Parts

The use of phytoconstituents single or combined with standard medicines has been utilized in cure of different diseases. Many plants of genus Cordia comprise of trees and shrubs are widely distributed in warmer regions and have been utilized in management of various diseases. Cordia africana Lam. (family- Boraginaceae) is a small to medium-sized evergreen tree, 4 to 15 (30) m high, heavily branched with a spreading, umbrella-shaped or rounded crown. Bole typically curved or crooked. Bark grayish-brown to dark brown, smooth in young trees, but soon becoming rough and longitudinally fissured with age; young branch lets with sparse long. Uses of C. africana: firewood, timber (furniture, beehives, boxes, mortars, church, drums), food (fruit), medicine (bark, roots), fodder (leaves), bee forage, mulch, soil conservation, ornamental, shade. Various phytoconstituents like flavonoids, alkaloids, tannins, terpenoids, saponins, steroids, anthraquinones, carbohydrates and protins having different activities were screened and isolated from different parts of Cordia africana. Various important Pharmacological properties including Antioxidant, Cytotoxicity, anti-inflammatory, anthelmintic, antimicrobial, anti-nociceptive, and others have been well documented for this plant. Therefore, we have briefly reviewed the various bioactivities of Cordia africana to improve our knowledge on plant phytochemicals as therapeutic entities. The present review describes the various phytoconstituents and therapeutic potential of Cordia africana that can be followed for future research on this plant for human health benefits.

Ethnomedicinal Uses, Phytochemistry, Pharmacology, and Toxicology of Species from the GenusAjugaL.: A Systematic Review

2019 ◽  
Vol 47 (05) ◽  
pp. 959-1003 ◽  
Author(s):  
Fei Luan ◽  
Keqing Han ◽  
Maoxing Li ◽  
Ting Zhang ◽  
Daoheng Liu ◽  
...  
Keyword(s):  
Current Knowledge ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Control Measures ◽  
Neuroprotective Activity ◽  
Extensive Literature ◽  
Data Quality Control ◽  
Toxicological Studies ◽  
Ethnomedicinal Uses

The present review is aimed at providing a comprehensive summary of the botanical characteristics, ethnomedicinal uses, phytochemical, pharmacological, and toxicological studies of the genus Ajuga L. The extensive literature survey revealed Ajuga L. species to be a group of important medicinal plants used for the ethnomedical treatment of rheumatism, fever, gout, sclerosis, analgesia, inflammation, hypertension, hyperglycemia, joint pain, palsy, amenorrhea, etc., although only a few reports address the clinical use and toxicity of these plants. Currently, more than 280 chemical constituents have been isolated and characterized from these plants. Among these constituents, neo-clerodane diterpenes and diterpenoids, phytoecdysteroids, flavonoids, and iridoids are the major bioactive compounds, possessing wide-reaching biological activities both in vivo and in vitro, including anti-inflammatory, antinociceptive, antitumor, anti-oxidant, antidiabetic, antimicrobial, antifeedant, antidiarrhoeal, hypolipidemic, diuretic, hypoglycaemic, immunomodulatory, vasorelaxant, larvicidal, antimutagenic, and neuroprotective activity. This review is aimed at summarizing the current knowledge of the ethnomedicinal uses, phytochemistry, biological activities, and toxicities of the genus Ajuga L. to reveal its therapeutic potentials, offering opportunities for future researches. Therefore, more focus should be paid to gathering information about their toxicology data, quality-control measures, and the clinical application of the bioactive ingredients from Ajuga L. species.

scholarly journals Shatavari (Asparagus Racemosus) - The Best Female Reproductive Tonic

2021 ◽  
Vol 8 (5) ◽  
pp. 73-84
Author(s):  
Shifali Thakur ◽  
Hemlata Kaurav ◽  
Gitika Chaudhary
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
World Health ◽  
Asparagus Racemosus ◽  
Pharmacological Properties ◽  
General Description ◽  
Wound Healing Effect ◽  
Ancient Times ◽  
Health Organization ◽  
Herbal Plant

It is recommended by the World health organization (WHO) the most of the world’s population depends on herbal medicine for their health care. Shatavari, Asparagus racemosus is one of the most significant restorative plant employed by Ayurvedic Vaidyas from ancient times. This herbal plant has wide selection of biological activities and described as a Rasayan in Ayurvedic literatures. Root is the most used part of Shatavari by Ayurvedic Vaidyas. It is one of the most common herbal plant used worldwide and possess various chemical constituents such as Racemoside A, B, C, Shatavarins, Asparanin A, Immunoside, 27 α-dimethyl-1β, 2β,3β-trihydroxy-25-spirost-4-en-19β-oic, 27 α-dimethyl-1β, 2β,3β-trihydroxy-25-spirost-4-en-19β-oic and many others. It is described as a tonic and have lactogenic properties. It has an extensive use in Nervine disorders, Acid peptic diseases, several contagious ailments and as a immunomodulant. It is primarily used in female ailments mainly as galactagogic and several menstrual problems. The chemical constituents of Asparagus racemosus have many pharmacological activities such as antibacterial, antiviral, anti-inflammatory, wound healing effect, antidepressant, anti-anxiety, antifertility and also skin cancer, pigmentation and many other. Much scientific research on Asparagus racemosus has been conducted over the last years to investigate chemical and pharmacological properties. In this review, the general description, phytochemicals, pharmacological properties, ayurvedic properties and folk uses of Asparagus racemosus are briefly explained. Keywords: Shatavari, Ayurveda, Saponins, Menstrual disorders, Anti-ulcer, Immunomodulatory.

scholarly journals Phytochemical and Pharmacological Properties of Some Species of the Genus Galium L. Galium Verum and Mollugo

2018 ◽  
Vol 0 (0) ◽  
Author(s):  
Jovana Bradic ◽  
Anica Petkovic ◽  
Marina Tomovic
Keyword(s):  
Current Knowledge ◽  
Chemical Constituents ◽  
Iridoid Glycosides ◽  
Future Research ◽  
Pharmacological Properties ◽  
Pharmacological Effects ◽  
Potential Health ◽  
The Past ◽  
History Of ◽  
History Of Use

Abstract Galium verum L. and Galium mollugo L. are perennial herbaceous plants, belonging to the Rubiaceae family. Several classes of bioactive compounds, such as iridoid glycosides, phenolic compounds, anthraquinones and triterpenes, as well as small amounts of tannins, saponins, essential oils have been isolated from Galium species so far. Plants belonging to this genus have a long history of use in a traditional medicine for the treatment of many diseases and conditions. Th e main application of G. verum is as diuretic, choleretic and as the treatment for gout and epilepsy. On the other hand, G. mollugo has been used to treat hysteria, epilepsy, as vulnerary. Over the past decades, numerous papers have been published referring to the chemical constituents presented in G. verum and G. mollugo extracts. Additionally, chemical composition and pharmacological effects of G. verum have been investigated, however data related to the effects of G. mollugo is limited. In this review, we summarized the current knowledge on the phytochemical and pharmacological properties of G. verum and G. mollugo. Finally, we proposed directions for future research in this field, which can improve our understanding of the potential health benefits of Galium species.

scholarly journals A Review of the Ethnomedicinal Uses, Biological Activities, and Triterpenoids of Euphorbia Species

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 4019
Author(s):  
Douglas Kemboi ◽  
Xolani Peter ◽  
Moses Langat ◽  
Jacqueline Tembu
Keyword(s):  
Drug Discovery ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Structural Diversity ◽  
Pharmacological Properties ◽  
Anticancer Activities ◽  
Sensory Disorders ◽  
Wide Range ◽  
Ethnomedicinal Uses

The genus Euphorbia is one of the largest genera in the spurge family, with diversity in range, distribution, and morphology. The plant species in this genus are widely used in traditional medicine for the treatment of diseases, ranging from respirational infections, body and skin irritations, digestion complaints, inflammatory infections, body pain, microbial illness, snake or scorpion bites, pregnancy, as well as sensory disorders. Their successes have been attributed to the presence of diverse phytochemicals like polycyclic and macrocyclic diterpenes with various pharmacological properties. As a result, Euphorbia diterpenes are of interest to chemists and biochemists with regard to drug discovery from natural products due to their diverse therapeutic applications as well as their great structural diversity. Other chemical constituents such as triterpenoids have also been reported to possess various pharmacological properties, thus supporting the traditional uses of the Euphorbia species. These triterpenoids can provide potential leads that can be developed into pharmaceutical compounds for a wide range of medicinal applications. However, there are scattered scientific reports about the anticancer activities of these constituents. Harnessing such information could provide a database of bioactive pharmacopeia or targeted scaffolds for drug discovery. Therefore, this review presents an updated and comprehensive summary of the ethnomedicinal uses, phytochemistry, and the anticancer activities of the triterpenoids of Euphorbia species. Most of the reported triterpenoids in this review belong to tirucallane, cycloartanes, lupane, oleanane, ursane, and taraxane subclass. Their anticancer activities varied distinctly with the majority of them exhibiting significant cytotoxic and anticancer activities in vitro. It is, therefore, envisaged that the report on Euphorbia triterpenoids with interesting anticancer activities will form a database of potential leads or scaffolds that could be advanced into the clinical trials with regard to drug discovery.

The Chemical Constituents and Bioactivities of Psoralea corylifolia Linn.: A Review

2016 ◽  
Vol 44 (01) ◽  
pp. 35-60 ◽  
Author(s):  
Xuenong Zhang ◽  
Wenwen Zhao ◽  
Ying Wang ◽  
Jinjian Lu ◽  
Xiuping Chen
Keyword(s):  
Medicinal Plant ◽  
Skin Diseases ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Psoralea Corylifolia ◽  
Active Components ◽  
Anti Oxidant ◽  
Main Components ◽  
Phytochemical Studies ◽  
Important Medicinal Plant

Psoralea corylifolia Linn. (P. corylifolia) is an important medicinal plant with thousands of years of clinical application. It has been widely used in many traditional Chinese medicine formulas for the treatment of various diseases such as leucoderma and other skin diseases, cardiovascular diseases, nephritis, osteoporosis, and cancer. Phytochemical studies indicated that coumarins, flavonoids, and meroterpenes are the main components of P. corylifolia, and most of these components are present in the seeds or fruits. The extracts and active components of P. corylifolia demonstrated multiple biological activities, including estrogenic, antitumor, anti-oxidant, antimicrobial, antidepressant, anti-inflammatory, osteoblastic, and hepatoprotective activities. This paper systematically summarized literatures on the chemical constituents and biological activities of P. corylifolia, which provided useful information for the further research and development toward this potent medicinal plant.

scholarly journals Current Knowledge and Perspectives of Pyrrolizidine Alkaloids in Pharmacological Applications: A Mini-Review

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1970
Author(s):  
Xianqin Wei ◽  
Weibin Ruan ◽  
Klaas Vrieling
Keyword(s):  
Secondary Metabolites ◽  
Pyrrolizidine Alkaloids ◽  
Current Knowledge ◽  
Biological Activities ◽  
New Drugs ◽  
Pharmacological Properties ◽  
Neurological Damage

Pyrrolizidine alkaloids (PAs) are a widespread group of secondary metabolites in plants. PAs are notorious for their acute hepatotoxicity, genotoxicity and neurological damage to humans and animals. In recent decades, the application of PAs for beneficial biological activities to cure disease has drawn greater attention. Here, we review the current knowledge regarding the pharmacological properties of PAs and discuss PAs as promising prototypes for the development of new drugs.

scholarly journals Phytoconstituents and Biological Activities of Garcinia Dulcis (Clusiaceae): A Review

2017 ◽  
Vol 12 (3) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Nanthaphong Khamthong ◽  
Nongporn Hutadilok-Towatana
Keyword(s):  
Current Knowledge ◽  
Biological Activities ◽  
Fruit Tree ◽  
Pharmacological Properties ◽  
Tropical Fruit ◽  
Anti Cancer ◽  
History Of ◽  
Phytochemical Constituents ◽  
History Of Use ◽  
Review Current

Garcinia dulcis (Roxb.) Kurz is a tropical fruit tree native to Southeast Asia where it has a long history of use as a traditional medicine for the treatment of ailments such as lymphatitis, parotitis, struma, scurvy, cough, and sore throat. Despite its medicinal values, this plant is not well known and rarely found nowadays. Research on the phytochemical constituents and biological activities of G. dulcis have demonstrated that various parts of the plant contain an abundance of bioactive compounds mainly xanthones and flavonoids, with significant pharmacological properties such as anti-atherosclerosis, anti-bacterial, anti-cancer, anti-hypertension, and anti-malarial. In the present review, current knowledge of the phytochemistry of G. dulcis and biological activities of its active constituents based on the available literature are summarized in order to explore application potentials and prospective research works on this plant.

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