scholarly journals Decayed, Missing, and Filled Teeth Index and Periodontal Health in Osteoporotic Patients Affected by BRONJ: An Observational Study

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Giacomo Oteri ◽  
Ennio Bramanti ◽  
Valentina Nigrone ◽  
Marco Cicciù

The aim of this paper is to describe the incidence of decayed, missing, and filled teeth (DMFT) and periodontal disease in 32 osteoporotic patients affected by bisphosphonate-related osteonecrosis of the jaw (BRONJ). Moreover, an investigation between the obtained data and 20 patients treated with bisphosphonate drugs and with no evidence of ONJ has been performed. Osteonecrosis of the jaws is a rare complication in a subset of patients receiving bisphosphonate drugs. Based on a growing number of case reports and institutional reviews, this kind of therapy can cause exposed and necrotic bone specifically in the jawbones. From April 2009 to June 2012, 32 osteoporotic patients treated with oral or intravenous (I.V.) bisphosphonates have been recorded. The patients’ oral health has been compared with 20 bisphosphonates patients with no ONJ. The incidence of decayed, missing, and filled teeth (DMFT) and periodontal disease was recorded in all patients and student’st-test was applied for comparing the two investigated groups data. Data demonstrated how the poor dental hygiene and periodontal disease of the BRONJ patients’ are connected with the occurrence of jawbone necrosis.

1998 ◽  
Vol 35 (3) ◽  
pp. 248-254 ◽  
Author(s):  
Fanny W. L. Wong ◽  
Nigel M. King

A review of the studies of the caries prevalence and periodontal health of patients with cleft lip and palate (CLP) revealed that only five investigations of caries prevalence in CLP patients included children. One reported that CLP children did not have a higher caries prevalence in the permanent dentition, whereas more recent studies have reported a higher caries prevalence in both the primary and permanent dentitions of CLP children than in those of noncleft children. However, there is wide variation in the teeth examined and the method of presenting data on caries prevalence. Six papers have reported on the periodontal health of adult CLP patients, and only one has done so on that of children. The adult CLP patients had poorer oral hygiene and more gingivitis, but there is no conclusive evidence that they have a higher risk of developing periodontal disease. No data on the oral hygiene of CLP children were available, but it has been emphasized that they have significantly more gingivitis than noncleft children, especially in the maxillary anterior teeth.


2010 ◽  
Vol 4 (Spl) ◽  
pp. 35-37
Author(s):  
Vivek Gupta ◽  
Bhavana Gupta

ABSTRACT Probiotics are live micro-organisms that when administered in adequate amounts confer health benefits upon the host. Although a lot of work has been done regarding the effects of probiotic applications on systemic health particularly gastro-intestinal, the impact of probiotics on oral health is relatively new with lots of research going on; the area of probiotics and periodontal disease is still in its infancy. The present article summarizes the role of probiotics in periodontal health and disease and its effectiveness in periodontal therapy.


Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 2818-2818
Author(s):  
Alessandro Andriani ◽  
Maria Teresa Petrucci ◽  
Tommaso Caravita ◽  
Marco Montanaro ◽  
Francesco Pisani ◽  
...  

Abstract Abstract 2818 Poster Board II-794 INTRODUCTION: Bisphosphonate (BSFs) are an effective drug which have been mainly used in oncology for the treatment of solid tumour with bone metastasis, as well as for haematologic disease such as multiple myeloma (MM) and Waldenstrom's Macroglobulinemia (WM), but also prescribed in non neoplastic disease such osteoporosis and Paget's disease. As rare complications related to prolonged treatment with BSFs, an osteonecrosis of the jaw (BRONJ) in neoplastic and non neoplastic diseases is reported with an incidence between 2 and 15% as described in different casitics. The aim of this retrospective multicentric study is to describe the clinical aspects and the evolution of the osteo-necrotic lesions in a long term group of MM patients treated with BSFs. MATERIAL AND METHODS: We studied retrospectively 55 patients (pts) with MM or WM who developed BRONJ followed from January 2003 to January 2009 in different haematological departments. Median age was 72 years (range 56-95), male 16/ 39 female. Immunoglobulin isotype was: 25 pts IgG-κ; 6 pts IgG-α, 12 pts IgA-κ; 3 pts IgA-γ, 5 pts IgM-κ (WM), 3 pts MM light chain κ and 1 pt MM light chain γ. All patients have been treated with BSFs for bone lesions and/or factures: Pamidronate was used in 1 pt (1,8 %), Zolendronic acid in 36 pts (65,5 %), Pamidronate followed by zolendronate in 18 pts (32,7 %). The average dose of Pamidronate was 2.022 mg (range 90-6.750 mg) and of zoledronate was 84 mg (range 4-256 mg). Anatomic localisation of the BRONJ was: mandible 29 pts (52,7%); maxilla 22 pts (40%); mandible/maxilla 4 cases (7,3 %). The most common trigger for BRONJ was dentoalveolar surgery, including extractions (43 cases-78,4%), dental implant placement (3 patients-5,4%), periodontal disease (5 cases-9 %), and in 3 patients with dental prothesis (5,4%); only 1 patient (1,8%) developed BRONJ spontaneously. All patients stopped bsf therapy after BRONJ diagnosis. RESULTS: After a median observation of 26 months (range 1-110 months) no death for BRONJ complication was reported. All patients were treated with conservative treatment such as antibiotic therapy. In 18 patients (32,7%) antibiotic therapy was the only treatment used. Six patients (10,9%) received antibiotic associated with surgical debridement of necrotic bone. Sixteen patients (29%) were treated with antibiotic therapy in combination with ozonotherapy and curettage; twelve patients (21, 8%) required sequestrectomy in association with antibiotic and oxygen/hyperbaric therapy. Three patients (5, 4%) refused any therapy. Among the evaluable patients (53) complete response (CR) was observed in 20 cases (37.75%); partial response (PR) in 21 patients (39.6%) with improving as secondary infection and pain; the clinical finding was unchanged (SD) in 9 patients (16,3%) and 3 patients (5,4%) developed a worsening of the osteonecrosis (PD). CONCLUSIONS: In the unvariate analysis association of surgical treatment with antibiotic therapy, is more effective to eradicate the necrotic bone than antibiotic treatment alone (p=<0.053). O2Iperbaric/Ozonotherapy is a very active treatment, because 44.4% of patient obtain complete resolution of ONJ in comparison to 30.8% of patients who didn't performed this procedure (p=<0.0007). A Multivariate analysis was performed to evaluate differences between variables, but no significant association was found. According to our retrospective study, we confirm that the incidence of this complication is between 2% and 15%, and the cumulative dosage of BSFs is important to induce ONJ. Because the most common trigger for BRONJ was dental extractions, it's an universally recognized indication before BSFs' treatment to implement control of periodontal disease, achieving optimal periodontal health. BRONJ is a late complication of the use of BSFs which interfere on quality of life of patients but not on survival because none death was observed. Disclosures: Petrucci: Ortho Biothec, Jannsen Cilag: Honoraria; Celgene: Honoraria.


Author(s):  
Suprim Malla ◽  
Reshma Shrestha ◽  
Bhageshwar Dhami ◽  
Sujaya Gupta ◽  
Satish Deo

Background: Periodontal disease is an inflammatory oral disease that affects the soft and hard tissues supporting the teeth. Gingivitis, an early stage, when untreated leads to periodontitis that causes progressive tooth mobility leading towards tooth loss. Periodontitis is ubiquitous and commonly manifests in adult life. Early detection of oral diseases makes them more amenable to treatment and allows better chance of cure. BDS students are young adults who are going to be future oral health care provider. Their knowledge and oral hygiene practices may impact oral health status of a society. Aims: The aim of this study was to evaluate the knowledge of oral health and periodontal disease and correlate it with oral hygiene practices among BDS students not exposed to clinical practice. Materials and Methods: This cross-sectional study was carried out among 120 students of first, second and third year BDS at Kantipur Dental College. The students who were not exposed to clinical practice were invited to participate. The data was collected by self-administered structured questionnaire. There were total of 15 questions on knowledge and oral hygiene practice and scores were assigned to each question. Data analysis was done by SPSS 20 software program. Results: The mean knowledge score of the population was 6.58 ± 1.29 and mean practice score as 6.20 ± 1.73. The participants had good knowledge (55%) of oral health and periodontal diseases. However, only 22.5% of participants followed good oral hygiene practices. There was no significant difference of knowledge between males and females (p = 0.831) but a statistically significant difference was seen in the practice of oral hygiene (p = 0.006). Conclusion: Despite having good knowledge (55%) of oral and periodontal health, 77.5% of the BDS students did not follow good oral hygiene practices on a regular basis. Dental students must be encouraged to be good role models in practicing as well as promoting oral health. The authors would like to recommend incorporating some oral health and preventive dentistry topics in the non-clinical BDS curriculum.  


2019 ◽  
Vol 45 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Stefano Storelli ◽  
Giulia Palandrani ◽  
Cristian Dondi ◽  
Luigi Tagliatesta ◽  
Alessandro Rossi

Osteonecrosis of the jaw is a rare complication that has been associated with the use of bisphosphonates. A 77-year-old patient presented in April 2013 asking for a consultation. She reported that in May 2009, she underwent an implant rehabilitation with 8 implants and an immediately loaded fixed prosthesis in the maxilla. After a few months the patient started to report pain and purulent secretions that were neglected by the clinician for several years. She decided to refer to the Dental Clinic after another acute pain episode. Once the fixed prosthesis was removed, exposed necrotic bone was found in relation to the implants. The patient reported having taken oral alendronic acid to treat osteoporosis since before 2006. The patient underwent a functional endoscopic sinus surgery and a removal of necrotic bone blocks. Three years of follow-up showed healed tissues with no recurrence, although the alveolar crest appeared irregular on radiographs.


2021 ◽  
Vol 10 (27) ◽  
pp. 1996-2000
Author(s):  
Raghavendra U.

BACKGROUND The attitude towards oral health reflects the overall health. Knowledge of health care professionals and their attitudes toward oral care corresponds to their understanding of the importance of preventive dental procedure and improving the oral health of patients. We wanted to assess the knowledge and practice regarding periodontal health / disease and oral hygiene among medical, ayurveda and homeopathy undergraduate students of Yenepoya (Deemed to Be University) (YU) and also determine their attitude and awareness towards oral health. METHODS The data related to their knowledge and practice towards the oral health was assembled using a self administered, validated questionnaire containing 13 questions which had multiple choice answers. The questionnaire was distributed through Google form among 341 medical, ayurveda and homeopathy undergraduate students of YU aged more than 17 years. RESULTS Survey responses were downloaded onto Google sheets and the data collected were coded, entered in Microsoft Excel and analysed using SPSS version 23 (Chicago, USA). Majority of study participants in different colleges showed lack of knowledge and practice regarding oral hygiene practices. To compare the mean scores of three colleges under YU for knowledge based and practice questions, ANOVA was performed. There was no significant difference found in knowledge and practice towards oral hygiene among medical, ayurveda and homeopathy colleges of YU. P < 0.05 was considered as statistically significant. CONCLUSIONS Professional health care students who will be the future backbone of the community health care have limited knowledge on periodontal disease and oral hygiene practices. There is no difference in knowledge and practices regarding oral hygiene among the students of medical, ayurveda and homeopathy colleges of YU. It highlights the need of incorporating oral health education in University curriculum for non dental students during their study period. KEY WORDS Knowledge, Practice, Periodontal Disease, Oral Hygiene Practices, Non-Dental Students, Oral Health Education


2015 ◽  
Vol 6 (3) ◽  
pp. 126-129 ◽  
Author(s):  
Danny Watts

Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious complication for patients undertaking treatment with antiresorptive or antiangiogenic agents. MRONJ is defined as an area of exposed necrotic bone in the maxilla or mandible persisting for more than eight weeks where there has been no history of radiotherapy or obvious metastatic disease to the jaws.1,2 The risk of developing MRONJ is greatest in patients receiving intravenous bisphosphonates, and the relatively low risk for those receiving bisphosphonates orally may be attributable to the route and frequency of bisphosphonate administration.3 Despite an increasing prevalence, the pathophysiology of MRONJ remains contentious.2


2021 ◽  
Vol 30 (03) ◽  
pp. 164-169
Author(s):  
Wardah Ahmed ◽  
◽  
Mehmil Aslam ◽  
Syed Imran Hassan Hassan ◽  
Khalil Ahmed ◽  
...  

OBJECTIVE: To Evaluate the level of oral health literacy (OHL) among new patients seeking care at the private teaching dental hospital. METHODOLOGY: A cross-sectional study conducted at Department of Oral Diagnosis & Periodontology at Private Teaching Dental Hospital. Adults (>18years) was recruited in the study using non-probability convenient sampling technique. Participants verbally consented to participate, then interview based validated questionnaire was administered. Data collected from April 2019 to August 2019. The study was approved by Scientific Review Committee of Private Teaching Dental Hospital. OHL was measured by REALD-20. Clinical assessment was performed using periodontal index. Two investigators and 2 house surgeons were trained for increasing inter-examiner reliability. Demographic variables were examined as exploratory covariates. Statistical analysis was performed using SPSS 21.Fisher’s exact test used to determine bivariate association and Multivariate regression analysis showed the relationship. RESULTS: The total sample size was n=236 out of which 100 (42.6%) were male and 136 (57.6%) were female. Mean age of the sample was 36 years (±13.6) and majority 150(64%) had 12 years of education completed. Smokers were 50 (21%) were smokers. Respondents 173(73.3%) brush at least once in a day and 93% used toothpaste as dentifrice. Respondents belong to low-OHL had moderate 84 (36%) and severe periodontal 72 (31%) diseases. The mean Periodontal Index Score: 2± 0.54. OHL was significantly associated with periodontal disease (p 0.01). Smokers showing significant association (p 0.04) with periodontal disease. Multivariate regression analysis revealed that for one- point decrease in OHL score, the occurrence of periodontal disease reduced by 25% (Adjusted OR=0.75). CONCLUSION:This has been concluded that oral health literacy associated with periodontal health status. Understanding of periodontal health knowledge and its implication is vital for prevention of periodontal diseases. Future intervention researches are required to develop etiological relationship between oral health literacy and periodontal health status. KEYWORDS: Periodontal disease, dental oral health, smokes adults


2021 ◽  
Vol 2 (5) ◽  
Author(s):  
Sthéffani Miguel Pereira ◽  
Giovanna Alves da Silva ◽  
Patrícia Garani Fernandes

Introduction: Periodontal disease is a chronic infection caused by a bacterium that stimulates the immunoinflammatory response, leading to inflammation of the gingival and tooth support tissue, resulting from the pathogenesis of the microorganism and the host's response. Studies have investigated the association between periodontal conditions and possible complications for pregnant women and newborns. Objective: Analyzed the main consequences of periodontal disease during pregnancy and childbirth, as well as changes involving newborns, in order to elucidate the importance of prenatal dental care. Methods: The present study was followed by a systematic literature review model, according to the PRISMA rules. Clinical studies included case reports, retrospective, prospective and randomized trials. The quality of the studies was based on the GRADE instrument. The risk of bias was analyzed according to the Cochrane instrument. Results: A total of 104 articles were found. A total of 48 articles were evaluated in full, and 20 were included and discussed in this study. The overall assessment did not result in significant risks that could compromise the science of the present study. According to the GRADE classification, the studies were of moderate quality. Gingivitis, periodontitis, and tooth loss were found to be associated with premature birth. Periodontal disease can increase the chance of negative neonatal and maternal outcomes, with fetal growth restriction, vulvovaginitis, and premature rupture of the membrane being the main effects. Conclusion: Oral health should be an important focus in the monitoring of pregnant women in all maternal and child health services, making it necessary to incorporate the diagnosis of maternal oral health and periodontal disease for the health of the mother and newborn.


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