scholarly journals Haemophilus influenzaeType b Meningitis in the Short Period after Vaccination: A Reminder of the Phenomenon of Apparent Vaccine Failure

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Noa Greenberg-Kushnir ◽  
Orly Haskin ◽  
Havatzelet Yarden-Bilavsky ◽  
Jacob Amir ◽  
Efraim Bilavsky
Keyword(s):  
Bacterial Meningitis ◽  
Haemophilus Influenzae ◽  
Type B ◽  
Vaccine Failure ◽  
Time Period ◽  
Short Period

We present two cases of bacterial meningitis caused byHaemophilus influenzaetype b (Hib) which developed a few days after conjugate Hib vaccination. This phenomenon of postimmunization provocative time period is reviewed and discussed. These cases serve as a reminder to clinicians of the risk, albeit rare, of invasive Hib disease in the short period after successful immunization.

Haemophilus influenzae Type b Polysaccharide-Diphtheria Toxoid Conjugate Vaccine in Vaccinated Children Who Developed Haemophilus Disease

PEDIATRICS ◽  
1990 ◽  
Vol 86 (4) ◽  
pp. 617-620
Author(s):  
GEOFFREY A. WEINBERG ◽  
TRUDY V. MURPHY ◽  
DAN M. GRANOFF
Keyword(s):  
Haemophilus Influenzae ◽  
Normal Serum ◽  
Antibody Responses ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Healthy Children ◽  
Type B ◽  
Vaccine Failure ◽  
Polyribosylribitol Phosphate ◽  
Conventional Type

Children in whom invasive Haemophilus influenzae type b disease develops despite previous immunization with conventional type b polysaccharide vaccine (polyribosylribitol phosphate [PRP]) have been reported to have impaired serum anticapsular antibody responses following recovery from H influenzae type b disease.1,2 Recently, these "vaccine failure" patients also have been found to have impaired antibody responses to reimmunization with PRP vaccine.3 The reasons are not understood because most of the children have normal serum concentrations of immunoglobulins, including IgG2.1-4 They also are more than 3 years of age at the time of reimmunization, an age group in which most healthy children respond to PRP vaccine.

Vaccination with Haemophilus influenzae type b conjugate vaccine reduces bacterial meningitis in Morocco

Vaccine ◽  
2012 ◽  
Vol 30 (15) ◽  
pp. 2594-2599 ◽  
Author(s):  
Mohamed Braikat ◽  
Abdelaziz Barkia ◽  
Naima El Mdaghri ◽  
Jeanette J. Rainey ◽  
Adam L. Cohen ◽  
...  
Keyword(s):  
Bacterial Meningitis ◽  
Haemophilus Influenzae ◽  
Conjugate Vaccine ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B

Adverse Reactions Reported Following Receipt of Haemophilus influenzae Type b Vaccine: An Analysis After 1 Year of Marketing

PEDIATRICS ◽  
1987 ◽  
Vol 80 (2) ◽  
pp. 270-274
Author(s):  
Julie B. Milstien ◽  
Thomas P. Gross ◽  
Joel N. Kuritsky
Keyword(s):  
Adverse Reaction ◽  
Haemophilus Influenzae ◽  
Adverse Reactions ◽  
Haemophilus Influenzae Type ◽  
First Year ◽  
Allergic Reactions ◽  
Haemophilus Influenzae Type B ◽  
Concurrent Infection ◽  
Type B ◽  
Vaccine Failure

An analysis of adverse reactions occurring after receipt of Haemophilus influenzae type b vaccine and reported to the Food and Drug Administration during the first year of marketing of the product was performed. During the period April 1985 to May 1986, adverse reaction reports on 152 patients, excluding those of vaccine failure and concurrent infection, were received. Several adverse reactions not previously recognized, including convulsions, allergic reactions such as anaphylactoid-like and serum sickness-like reactions, and vomiting were received. The vast majority of adverse reactions were benign. Because there are many biases that result in the reporting of or failure to report an adverse reaction, it is not possible to derive a rate of reactions from these data. Furthermore, causality cannot be inferred from any single report. The data, however, indicate that, in light of widespread use of the vaccine, its use appears to be safe.

scholarly journals Meningitis and bacteremia caused by Haemophilus influenzae Type e in an immunocompetent child

2021 ◽  
Vol 15 (09) ◽  
pp. 1356-1358
Author(s):  
Wenling Li ◽  
Jinhua Meng ◽  
Hui Xu ◽  
Liang Li ◽  
Junna Zhou ◽  
...  
Keyword(s):  
Bacterial Meningitis ◽  
Haemophilus Influenzae ◽  
Invasive Disease ◽  
Haemophilus Influenzae Type ◽  
Type B ◽  
Immunocompetent Child ◽  
Adults And Children ◽  
Common Serotypes ◽  
The Common

Haemophilus influenzae infection is a well-known cause of serious invasive disease in adults and children. But incidence of the common serotypes are type b, f and a. There is very little information available on invasive disease of Haemophilus influenzae type e (Hie) in China, especially in children. We report a case of an immunocompetent child who was clinically diagnosed with bacterial meningitis with bacteremia caused by Hie. The literature on infection especially meningitis caused by Hie is reviewed.

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