scholarly journals MR Imaging of Intra- and Periarticular Cyst-Like Lesions of the Knee Joint in Workers with Occupational Kneeling

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Søren Rytter ◽  
Lilli Kirkeskov Jensen ◽  
Jens Peter Bonde ◽  
Niels Egund
Keyword(s):  
Knee Joint ◽  
Regression Models ◽  
Anterior Part ◽  
Knee Injuries ◽  
Posterior Part ◽  
Popliteus Tendon ◽  
Cystic Lesions ◽  
Logistic Regression Models ◽  
Significant Difference ◽  
Fluid Collections

Objective. To determine the risk of intra- and periarticular cyst-like lesions of the knee joint in occupational kneeling.Methods. Magnetic resonance imaging of both knees (n=282) was conducted in 92 male floor layers and 49 male graphic designers (referents), with a mean age of 55.6 years (range 42–70 years). The prevalence of cyst-like lesions was computed among floor layers and graphic designers, respectively, and associations with occupation summarized by odds ratio (OR) with 95% confidence intervals (CIs). Using logistic regression, models were adjusted for age, body mass index, knee injuries, and knee-straining sports.Results. Floor layers had a significantly higher prevalence of cyst-like lesions in the posterior part of the knee joint compared to graphic designers (OR 2.70, 95% CI 1.50–4.84). Floor layers also had a higher prevalence of fluid collections in the popliteus tendon recess (OR 2.17, 95% CI 0.99–4.77) and large cystic lesions of the popliteus muscle (OR 3.83, 95% CI 0.78–18.89). The prevalence of cystic lesions in the anterior part of the knee joint was low among floor layers (8.7%) and there was no significant difference between the two trade groups (P=0.34).Conclusions. Occupational kneeling increases the risk of cyst-like lesions in the posterior part of the knee joint.

scholarly journals Acute primary repair of extraarticular ligaments and staged surgery in multiple ligament knee injuries

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Yasuyuki Ishibashi ◽  
Yuka Kimura ◽  
Eiji Sasaki ◽  
Shizuka Sasaki ◽  
Yuji Yamamoto ◽  
...  
Keyword(s):  
Knee Joint ◽  
Primary Repair ◽  
Cruciate Ligament ◽  
Stress Test ◽  
Knee Injuries ◽  
Joint Stability ◽  
Posterior Drawer ◽  
Staged Surgery ◽  
Significant Difference ◽  
Repair Group

Abstract Background The purpose of this study is to compare the outcomes of acute primary repair of extraarticular ligaments with staged surgery for acute knee dislocations (KDs) and multiligament knee injuries (MLKIs). Materials and methods Between January 2005 and May 2018, 61 consecutive patients diagnosed with MLKI or KD were referred to or visited our institution. Of these, 31 patients who underwent acute repair of extraarticular ligaments within 3 weeks of injury were included in this study. These patients were retrospectively classified into two groups: those who underwent only primary repair (repair group) and those who underwent staged reconstructive surgery (staged group). Follow-up examination included range of motion (ROM), knee joint stability (Lachman test, posterior drawer test, and varus and valgus stress test), Lysholm knee score, Tegner activity scale, and Knee Injury and Osteoarthritis and Outcome Score (KOOS). Results Twelve of the 31 patients did not need or desire further surgery and were included in the repair group. No significant difference was observed in demographic data between the repair and staged groups. Although staged surgery decreased positive posterior drawer test results, no significant difference was observed between the two groups regarding ROM, other knee joint stability tests, Lysholm scores, Tegner scale, or KOOS. Conclusions In this series, all patients returned to their activities of daily living and preinjury occupation levels. Acute primary repair of extraarticular ligaments provides essential knee stability without varus/valgus instability and may reduce the need for subsequent cruciate ligament reconstruction. Level of evidence Level IV, retrospective observational study.

scholarly journals Association between Sleep duration and Incidence of type 2 Diabetes in China

2020 ◽  
Author(s):  
Hongzhou Liu ◽  
Anping Wang ◽  
Junping Wen ◽  
Yimin Mu ◽  
Jingtao Dou ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Sleep Duration ◽  
Regression Models ◽  
Male Body ◽  
Night Sleep ◽  
Logistic Regression Models ◽  
Significant Difference ◽  
Long Sleep ◽  
The Relationship

Abstract Objective: We assess the relationship between night sleep duration and the incidence of type 2 diabetes in China.Methods: We used logistic regression models to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the incidence of type 2 diabetes among 11,539 participants at baseline from the REACTION cohort.Results: Compared to people who sleep for 7-8 h/night, people with a longer sleep duration (≥9 hours/night) had a greater risk of type 2 diabetes (hazard ratio [OR] 1.27; 95% confidence interval [CI]1.01–1.61), while shorter sleep (<6 h/night) had no significant difference. When the dataset was stratified based on selected covariates, the association between type 2 diabetes and long sleep duration became more evident among individuals < 65 years of age, male, body mass index<24 or with hypertension or hyperlipidemia, no interaction effects were observed. Furthermore, compared to people persistently sleeping 7–9 h/night, those who persistently slept ≥9 h/night had a higher risk of type 2 diabetes. The optimal sleep duration was 6.3-7.5 h/night.Conclusion: Short or Long sleep duration were associated with a high risk of type 2 diabetes. Persistently long sleep duration increased the risk. The optimal sleep duration was 6.3-7.5 hours/night.

scholarly journals Efficacy of three COS protocols and predictability of AMH and AFC in women with discordant ovarian reserve markers: a retrospective study on 19,239 patients

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Yaxin Guo ◽  
Huahua Jiang ◽  
Shiqiao Hu ◽  
Shuai Liu ◽  
Fei Li ◽  
...  
Keyword(s):  
Regression Models ◽  
Birth Rate ◽  
Gnrh Antagonist ◽  
Live Birth Rate ◽  
Multivariate Logistic Regression ◽  
Logistic Regression Models ◽  
Significant Difference ◽  
Group 3 ◽  
Group 2 ◽  
Long Protocol

Abstract Background Recent studies have consistently shown that AFC and serum AMH are good predictors of ovarian response and have shown strong correlations. However, it is not unusual for reproductive medicine specialists to encounter discordance between them. This is the first study to investigate the efficacies of the different COS protocols when the AFC and AMH levels are discordant. Based on the association between COS protocols and pregnancy outcomes, we attempt to explain the controversial results and clarify the predictive value of AMH and AFC in this context. Methods 19,239 patients undergoing their first fresh in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles with GnRH antagonist protocols, GnRH-a long protocols or GnRH-a ultra-long protocols between January 1, 2016, and December 31, 2019, were enrolled and then divided into four groups in accordance with the boundaries for the AFC and serum AMH level provided by the Poseidon Classification. Our study was divided into two parts. Firstly, we retrospectively compared the effects of the three COS protocols in patients with discordant AMH and AFC. Multivariate logistic regression models were conducted in a forward manner to exclude the influence of confounding factors. Afterward, to increase comparability between Group 2 (low AMH and normal AFC) and Group 3 (normal AMH and low AFC), propensity score matching (PSM) analysis was performed based on age, BMI, the number of embryos transferred, and COS protocol. IVF intermediate and reproductive outcomes were compared between Group 2 and Group 3. Results For people with low AMH and normal AFC (Group 2), the number of total oocytes, clinical pregnancy rate (CPR), live birth rate (LBR) and cumulative live birth rate (CLBR) were significantly higher in GnRH-a ultra-long protocol compared with GnRH antagonist protocol. In multivariate logistic regression models, significant associations of COS protocol with fresh LBR and CPR were found after adjusting for age, BMI, AFC, AMH and the number of embryos transferred. Whereas, in patients with normal AMH and low AFC (Group 3), the number of total oocytes, CLBR, LBR and CPR were highest in the long GnRH-a protocol although there was no statistically significant difference. After PSM, the results showed that although oocytes yield and available embryos in patients with normal AMH and low AFC were significantly higher, there was no significant difference in reproductive outcomes between Group 2 and Group 3. Conclusions We found that women with normal AFC and low AMH may benefit from the GnRH-a ultra-long protocol. Nevertheless, for women with normal AMH and low AFC, the long GnRH-a protocol seems to be associated with better clinical outcomes. Furthermore, after eliminating the confounding factors including the COS protocol, we found that AMH can only predict the number of oocytes but not the quality of oocytes when there was discordance between AFC and AMH.

scholarly journals Prevalence, nature and risk factors for medication administration omissions in English NHS hospital inpatients: a retrospective multicentre study using Medication Safety Thermometer data

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e028170 ◽  
Author(s):  
Paryaneh Rostami ◽  
Calvin Heal ◽  
Abigail Harrison ◽  
Gareth Parry ◽  
Darren M Ashcroft ◽  
...  
Keyword(s):  
Medication Safety ◽  
Regression Models ◽  
Medication Administration ◽  
Logistic Regression Models ◽  
Final Study ◽  
Substantial Problem ◽  
Significant Difference ◽  
Hospital Patients ◽  
Medical Wards ◽  
Hospital Inpatients

ObjectiveTo determine the prevalence, nature and predictors of patients having medication administration omissions in hospitals.MethodsAll medication administration omissions data collected using the standardised methodology of the Medication Safety Thermometer in January 2015 were examined. Hospital inpatients prescribed at least one medication were included in the analysis. Multilevel logistic regression models ascertained the effects of patients’ gender, age, number of prescribed medicines, ward specialty and medicines reconciliation initiation status on the likelihood of having omissions. Valid clinical reasons (VCRs) were excluded from regression models. A sensitivity analysis, excluding patient refusal (PR) omissions, was also conducted.ResultsThe final study sample included 5708 patients from 320 wards in 37 hospitals. Excluding VCRs, 30% of patients had medication administration omissions (95% CI 29 to 30). Approximately half of patients with omissions had refused medicines (51%, 95% CI 49 to 53). Univariable analysis suggested that all variables were significantly associated with omissions. However, in the multivariable model, significant differences were only observed regarding the numbers of medicines patients were prescribed and their ward specialty. Patients prescribed more than 20 medications were approximately five times more likely to have had omissions than patients prescribed one to four medications (OR 4.99, 95% CI 3.22 to 7.73). Patients on surgical wards were also more likely to have had omissions than those on medical wards (OR 1.58, 95% CI 1.14 to 2.18, p=0.006), but there was no significant difference when PRs were excluded (OR 0.5, 95% CI 0.27 to 1.22, p=0.473).ConclusionMedication administration omissions are a substantial problem that affect many hospital patients, and certain patient groups are at higher risk. Specific interventions are required targeting the underlying reasons for medication omissions for different patient subgroups.

scholarly journals FRI0313 DOES INTERSTITIAL LUNG DISEASE REPRESENT A REAL COMORBIDITY IN SPONDYLOARTHRITIS PATIENTS? RESULTS FROM AN ULTRASOUND MONOCENTRIC PILOT STUDY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 747.2-747
Author(s):  
A. Delle Sedie ◽  
E. Calabresi ◽  
I. Romagnoli ◽  
L. Carli ◽  
M. Mosca
Keyword(s):  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Anterior Part ◽  
Pulmonary Function Tests ◽  
Disease Onset ◽  
Posterior Part ◽  
Average Value ◽  
Significant Difference ◽  
Similar Disease ◽  
Low Sensitivity

Background:Interstitial lung disease (ILD) is a frequent complication in rheumatoid arthritis (RA) where it represents the most common extra-articular involvement (with a prevalence of about 10-60%) and the second cause of mortality (after cardiovascular diseases). Spondyloarthritides (SpA) are chronic arthritides that share with RA both a similar disease burden and similar therapeutical approaches. ILD evaluation is challenging, given the low sensitivity of X-ray and pulmonary function tests, and radiation linked to repetitive HRCT. Lung Ultrasound (LUS) has shown potential in the evaluation of ILD in autoimmune diseases.Objectives:To assess the prevalence of ILD in a cohort of SpA patients (pts) using LUS with respect to healthy controls (HC).Methods:Consecutive SpA out-pts were examined by LUS, applying the definition for pleural line irregularity (PLI) recently provided by the OMERACT taskforce for LUS in systemic sclerosis (1). Seventy-one intercostal spaces were studied (14 in the anterior chest, 27 lateral and 30 posterior) in all the pts/HC using an Esaote MyLab25 Gold US machine with a linear 7.5-10 MHz probe. The scoring system by Pinal-Fernandez et al (2) was applied and a total pleural score was calculated. Each patient answered to Italian-validated PROs on respiratory function (Leicester and Saint-George), global health (SF-36) and dyspnea (mMRC scale). Clinical data on disease-duration, disease-onset, disease-activity (at the moment of the examination) and MTX/biologics treatment were collected from the medical records.Results:Fifty-six SpA pts (35 psoriatic arthritis -PsA- and 21 ankylosing spondylitis -AS-) and 56 HC were studied. No significant differences were demonstrated between groups (SpA vs HC and PsA vs AS) for age, sex, BMI and smoking habits. The total pleural score was significantly higher in SpA pts than in HC (20.9±11.8 vs 10.3±7.7; p<0.001). A positive correlation was found between total PLI score and PLI score from anterior, posterior and lateral chest. The posterior part of the chest showed a higher PLI score than the anterior and lateral one (with the latter resulting to be significantly lower than the posterior PLI score). Higher differences in the PLI average value between SpA pts and HC were registered for posterior and anterior part of the chest. No differences were found between PsA and AS (with a not statistically significant difference in the posterior PLI score, which was slightly higher in AS pts) (Tab.I).Table 1.average PLI score (N±SD)TotalAnteriorPosteriorLateralHC10.3 ± 7.74 ± 3.25 ± 3.71.4 ± 2.2PsA20.1 ± 12.56.8 ± 3.910.2 ± 6.92.9 ± 4.1AS22.1 ± 10.77 ± 2.812 ± 9.53 ± 3.1Conclusion:LUS examination shows a higher amount of PLI in SpA with respect to HC.References:[1]Delle Sedie A et al. Ann Rheum Dis 2019;78(Suppl 2):A834[2]Pinal-Fernandez I et al. Clin Exp Rheumatol 2015;33(4 Suppl 91):S136-41Disclosure of Interests:Andrea Delle Sedie Speakers bureau: MSD, Lilly, Novartis, Abbvie, Celgene, Emanuele Calabresi: None declared, Ilaria Romagnoli: None declared, Linda Carli: None declared, Marta Mosca: None declared

scholarly journals Biomechanical Characteristics on the Lower Extremity of Three Typical Yoga Manoeuvres

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Elizabeth Whissell ◽  
Lin Wang ◽  
Pan Li ◽  
Jing Xian Li ◽  
Zhen Wei
Keyword(s):  
Knee Joint ◽  
Lower Extremity ◽  
Hip Joint ◽  
Sagittal Plane ◽  
Knee Injuries ◽  
Three Dimensional ◽  
Knee Extensor ◽  
Frontal Plane ◽  
Significant Difference ◽  
Angular Impulse

This study was aimed at exploring the biomechanical characteristics of the lower extremity amongst three typical yoga manoeuvres. A total of thirteen experienced female yoga practitioners were recruited in the current study; they were all certified with the Yoga Alliance. A three-dimensional motion capture system with 10 cameras combined with four synchronised force plates was used to collect kinematics of the lower extremity and ground reactive force whilst the participants performed the crescent lunge pose, warrior II pose, and triangle pose. One-way repeated ANOVA was used in exploring the differences amongst the three yoga movements, and the significance was set to alpha < 0.05 . The triangle pose performed the largest range of motion (ROM) of the hip ( 90.5 ° ± 22.9 ° ), knee ( 68.8 ° ± 23.1 ° ), and ankle ( 46.4 ° ± 11.3 ° ) in the sagittal plane and the hip ( 54.8 ° ± 6.5 ° ), knee ( 42.4 ° ± 12.8 ° ), and ankle ( 4.8 ° ± 1.7 ° ) in the frontal plane amongst the three manoeuvres ( P < 0.05 ). No significant difference was found for the hip and ankle joint moment amongst the three manoeuvres ( P > 0.05 ). Knee joint travelled into 9.5° of extension and slight adduction of 1.94° whilst expressing the largest knee joint adduction moments ( 0.30 ± 0.22   Nm / kg ) in the triangle pose. The distribution of the angular impulse of the lower limb joints indicated that the hip joint contributed significantly the most in the sagittal and frontal planes of the three yoga manoeuvres ( P < 0.05 ), ranging from 51.67% to 70.56%. Results indicated that triangle pose may be superior to the other two manoeuvres, which improved hip joint ROM, strength, and dynamic stability. However, knee injuries such as osteoarthritis (OA) should be considered because of the large knee extensor angle and adductor moments.

scholarly journals Frequency of Going Out and Locomotive Syndrome Among Japanese Female Elderlies

2019 ◽  
Vol 12 (1) ◽  
pp. 80
Author(s):  
Fumie Okada ◽  
Satoshi Toyokawa ◽  
Takehiko Kaneko ◽  
Tadashi Furuhata
Keyword(s):  
Regression Models ◽  
Preventive Measure ◽  
Household Composition ◽  
Locomotive Syndrome ◽  
Logistic Regression Models ◽  
Significant Difference ◽  
The World ◽  
Japanese Female ◽  
Aged Society ◽  
The Relationship

Background: Japan is the world&rsquo;s leading super-aged society, which makes locomotive syndrome an urgent issue. Because increasing the frequency of going out is considered a practical primary preventive measure against locomotive syndrome, we examined the relationship between the frequency of going out and locomotive syndrome in elderly females in Japan. Methods: The subjects were 8,027 females from 46 prefectures in Japan who were living at home and aged 65 and older as of November 1, 2012. The study period was from November 1 to December 31, 2012. The survey was implemented by distributing questionnaires, as well as conducting face&ndash;to&ndash;face interviews. Odds ratios were obtained using logistic regression models with locomotive syndrome as the dependent variable. Results: Eight thousands twenty seven females were analyzed in this study. There was a significant difference in the prevalence of locomotive syndrome depending on the frequency of going out (p&lt;0.001) as the prevalence of locomotive syndrome decreased as the frequency of going out increased. When the results were adjusted for gender, the frequency of going out, age, use of national nursing&ndash;care insurance services, household composition, severity of obesity, and self-rated health, the prevalence of locomotive syndrome was high in those whose frequency of going out was &ldquo;twice or less a week&rdquo; (Odds ratio: 1.41, 95% Confidence interval 1.20&ndash;1.64). Conclusions: The results suggest that it is possible to prevent locomotive syndrome by encouraging elderly people to maintain and increase their frequency of going out.

scholarly journals Radiogenomics prediction for MYCN amplification in Neuroblastoma: a hypothesis generating study

2021 ◽  
Author(s):  
Angela Di Giannatale ◽  
Pierluigi Di Paolo ◽  
Davide Curione ◽  
Jacopo Lenkowicz ◽  
Antonio Napolitano ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Models ◽  
Pearson Correlation ◽  
Area Under The Curve ◽  
Clinical Information ◽  
Mycn Amplification ◽  
Features Selection ◽  
Logistic Regression Models ◽  
Significant Difference ◽  
Depth Analysis

Background: MYCN amplification represents a powerful prognostic factor in neuroblastoma (NB) and may occasionally account for intratumoral heterogeneity. Radiomics is an emerging field of advanced image analysis that aims to extract a large number of quantitative features from standard radiological images, providing valuable clinical information Procedure: In this retrospective study, we aimed to create a radiogenomics model by correlating computed tomography (CT) radiomics analysis with MYCN status and overall survival (OS). NB lesions were segmented on pre-therapy CT scans and radiomics features subsequently extracted using a dedicated library. Dimensionality reduction/features selection approaches were then used for features procession and logistic regression models have been developed for the considered outcome. Results: Seventy-eight patients were included in this study, 24 presented MYCN amplification. In total, 232 radiomics features were extracted. Eight features were selected through Boruta algorithm and 2 features were lastly chosen through Pearson correlation analysis: mean of voxel intensity histogram (p=0.0082) and zone size non-uniformity (p=0.038). Five-times repeated 3-fold cross-validation logistic regression models yielded an Area Under the Curve (AUC) value of 0.879 on the training and 0.865 on the testing set for MYCN. No statistical significant difference has been observed comparing radiomics predicted and actual OS data. Conclusions: CT based radiomics is able to predict MYCN amplification status and OS in NB, paving the way to the in depth analysis of imaging based biomarkers that could enhance outcomes prediction.

Fine structure of the rectal papillae of the oriental fruuit fly, Dacus dorsalis Hendel (Tephritidae, Diptera Insecta)

1990 ◽  
Vol 48 (3) ◽  
pp. 498-499
Author(s):  
Len Wen-Yung ◽  
Mei-Jung Lin
Keyword(s):  
Fine Structure ◽  
Cell Membrane ◽  
Intercellular Space ◽  
Anterior Part ◽  
Apical Cell ◽  
Posterior Part ◽  
Apical Cell Membrane ◽  
Dacus Dorsalis ◽  
Radial Cell ◽  
Circular Base

Four cone-shaped rectal papillae locate at the anterior part of the rectum in Dacus dorsalis fly. The circular base of the papilla protrudes into the haemolymph (Fig. 1,2) and the rest cone-shaped tip (Fig. 2) inserts in the rectal lumen. The base is surrounded with the cuticle (Fig. 5). The internal structure of the rectal papilla (Fig. 3) comprises of the cortex with the columnar epithelial cells and a rod-shaped medulla. Between them, there is the infundibular space and many trabeculae connect each other. Several tracheae insert into the papilla through the top of the medulla, then run into the cortical epithelium and locate in the intercellular space. The intercellular sinuses distribute in the posterior part of the rectal papilla.The cortex of the base divides into about thirty segments. Between segments there is a radial cell (Fig. 4). Under the cuticle, the apical cell membrane of the cortical epithelium is folded into a regular border of leaflets (Fig. 5).

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