scholarly journals Lichen Sclerosus Atrophicus [LSA] in the Areolae: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
L. Padmavathy ◽  
L. Lakshmana Rao ◽  
M. Dhana Lakshmi ◽  
N. Sylvester ◽  
N. Ethirajan
Keyword(s):  
Case Report ◽  
Lichen Sclerosus ◽  
Inflammatory Disorder ◽  
Unknown Aetiology ◽  
Chronic Inflammatory Disorder ◽  
Anogenital Area

Lichen sclerosus (LS) is a chronic inflammatory disorder of an unknown aetiology most commonly affecting the anogenital area. However, extragenital involvement also occurs uncommonly. A case of extra-genital LS involving the areolae of both breasts, in a 15-year-old boy, is reported for its rarity.

scholarly journals Rituximab Treatment in a Patient with Kimura Disease and Membranous Nephropathy: Case Report

2021 ◽  
pp. 116-123
Author(s):  
Roald Vissing-Uhre ◽  
Alastair Hansen ◽  
Susanne Frevert ◽  
Ditte Hansen
Keyword(s):  
Case Report ◽  
Membranous Nephropathy ◽  
Neck Region ◽  
Renal Diseases ◽  
Kimura’S Disease ◽  
Inflammatory Disorder ◽  
Kimura Disease ◽  
Chronic Inflammatory Disorder ◽  
Eosinophil Granulocytes ◽  
Anti Cd20

Kimura disease (KD) is a chronic, inflammatory disorder with slowly developing subcutaneous tumor-like swellings, often occurring in the head and neck region. KD is diagnosed based on histology, elevated levels of immunoglobulin type E, and increased peripheral eosinophil granulocytes. KD may coexist with glomerular renal diseases, and this case report is based on a patient with KD-associated membranous nephropathy. Patients with membranous nephropathy without KD have demonstrated responsiveness to treatment with monoclonal anti-CD20 antibodies. This case report is the first to investigate the effect of rituximab treatment in a patient with KD-associated membranous nephropathy. A 30-year-old Italian man living in Denmark was diagnosed with Kimura’s disease based on subcutaneous nodules with eosinophil angiolymphoid hyperplasia. The patient was admitted to the hospital due to nephrotic syndrome. Serology showed eosinophil granulocytosis and negative PLA2-receptor antibody. Renal biopsy showed membranous nephropathy, and the patient was treated with systemic methylprednisolone followed by cyclosporin and then cyclophosphamide with only partial remission. Ultimately, treatment with intravenous rituximab was initiated, which resulted in overall remission and no nephrotic relapses at 30 months of follow-up. Thus, intravenous rituximab effectively decreased proteinuria and prevented nephrotic relapses in a patient with treatment-refractory membranous nephropathy due to KD.

scholarly journals Kimura's Disease: A Rare Cause of Postauricular Swelling

2017 ◽  
Vol 25 (1) ◽  
pp. 59-61 ◽  
Author(s):  
Suman Kumar Das ◽  
Mukesh Kumar Singh ◽  
Indranath Kundu ◽  
Swapan Kumar Ghosh
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Indian Population ◽  
Disease Patient ◽  
Invasive Procedure ◽  
Excision Biopsy ◽  
High Dose ◽  
Kimura’S Disease ◽  
Inflammatory Disorder ◽  
Chronic Inflammatory Disorder

Introduction Kimura’s Disease is a chronic inflammatory disorder of lymph node which is very rare in Indian population. Case Report A 15 year old boy with multiple postauricular swelling for 18 months presenting in OPD and diagnosed having eosinophilia. Then excision biopsy was taken, which indicates Kimura’s Disease. Patient was treated with high dose of corticosteroid. Conclusion Kimura’s disease, though rare should be kept in mind for treating a patient with lymphadenopathy with eosinophilia or high IgE level, because it can spare the patient unnecessary invasive procedure.

Recurrent Kimura’s disease of head and neck treated with intensity-modulated radiotherapy

2021 ◽  
Vol 14 (3) ◽  
pp. e239064
Author(s):  
Jeyaanth Venkatasai ◽  
Arvind Sathyamurthy ◽  
Jeba Karunya Ramireddy ◽  
Thomas Samuel Ram
Keyword(s):  
Intensity Modulated Radiotherapy ◽  
Kimura’S Disease ◽  
Inflammatory Disorder ◽  
Unknown Aetiology ◽  
Chronic Inflammatory Disorder ◽  
Intensity Modulated ◽  
Integrated Boost ◽  
Good Local Control ◽  
Primary Modality

Kimura’s disease (KD) is a rare, chronic inflammatory disorder of unknown aetiology, which commonly affects men of the Asian race. Here, we present a case capsule of a 39- year-old man with KD of the left cheek, managed initially by surgery alone. He developed local recurrence after 6 months and was treated with steroids and isotretinoin. Eventually, steroids were discontinued due to toxicity and the lesion progressively increased in size. The patient was successfully treated using intensity-modulated radiotherapy with simultaneous integrated boost as a primary modality with minimal adverse effects. The patient has good local control and cosmetic outcome with no radiation-related toxicity at a follow-up period of 28 months.

scholarly journals Lichen sclerosus: a clinical study

2017 ◽  
Vol 3 (4) ◽  
pp. 481
Author(s):  
Sandhyarani Kshetrimayum ◽  
Nandakishore Singh Thokchom ◽  
Vanlalhriatpuii . ◽  
N. A. Bishurul Hafi
Keyword(s):  
Systemic Disease ◽  
Lichen Sclerosus ◽  
Signs And Symptoms ◽  
Inflammatory Disorder ◽  
Systemic Diseases ◽  
Adequate Treatment ◽  
Balanitis Xerotica Obliterans ◽  
Chronic Inflammatory Disorder ◽  
Labia Minora ◽  
Uncommon Disease

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Lichen sclerosus (LS) is a chronic inflammatory disorder that preferentially affects the anogenital region and rarely extra genital sites. It is more common in women and has a bimodal peak of incidence. The objective of the study was to document the clinical, demographic pattern and associated systemic diseases of lichen sclerosus (LS) among patients attending skin OPD, RIMS, Imphal.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">All patients presenting with signs and symptoms suggestive of lichen sclerosus (LS) were studied for a period of 24 months from March 2014 to February 2016. Clinical examination and relevant investigations including histopathology were performed</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">A total of 54 patients were studied (17 males and 37 females). M:F ratio was 1:2.2. Majority belonged to 25-44 years age group (29.6%). Ano-genital LS comprised 81.4% of the cases. All patients presented with hypopigmented atrophic plaque (100%). The commonest site was prepuce (53.3%) in males and labia majora, labia minora and clitoris (62%) in females. There were 2 cases of balanitis xerotica obliterans (BXO). Ten patients (18.6%) had extragenital LSA and the sites involved were trunk, waist and extremities. Associated systemic diseases were detected in 6 patients. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Lichen sclerosus is not an uncommon disease. Varied presentations ranging from asymptomatic white patch to severe inflammation and scarring were noted. Complications especially with genital involvement can be prevented by early diagnosis and adequate treatment. Screening for associated systemic disease may prove useful.</span></p>

scholarly journals Malakoplakia of the parotid gland: a case report and review of localised malakoplakia of the head and neck

2019 ◽  
Vol 101 (5) ◽  
pp. 309-312
Author(s):  
C Samian ◽  
S Ghaffar ◽  
V Nandapalan ◽  
S Santosh
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Parotid Gland ◽  
Head And Neck ◽  
World Literature ◽  
Neck Region ◽  
Submandibular Salivary Gland ◽  
Inflammatory Disorder ◽  
Head And Neck Region ◽  
Chronic Inflammatory Disorder

Introduction Malakoplakia is a rare chronic inflammatory disorder, predominantly affecting the urinary tract. In the head and neck region, it is very rare and may confuse the clinicians during investigations, as features may mimic malignancy. Materials and methods We report a case of malakoplakia involving the parotid gland and review of the reported cases of malakoplakia in head and neck region. Results Histologically, this is the first classic case report of malakoplakia involving the parotid gland in the world literature. A total of 49 cases have been reported in the head and neck region; 38.7% of these are cutaneous. In soft tissue, the tongue is the most common site. Salivary gland involvement is very rare. Previously, submandibular salivary gland involvement has been reported. Conclusion A possibility of malakoplakia should be considered as a differential diagnosis in patients with enlarged head and neck masses. Histology is essential to diagnose this benign inflammatory disorder and to differentiate from a malignant process.

Lichen sclerosus

2005 ◽  
Vol 16 (7) ◽  
pp. 465-474 ◽  
Author(s):  
P D Yesudian ◽  
H Sugunendran ◽  
C M Bates ◽  
C O'Mahony
Keyword(s):  
Age Groups ◽  
Lichen Sclerosus ◽  
Inflammatory Disorder ◽  
Cell Degeneration ◽  
Balanitis Xerotica Obliterans ◽  
Chronic Inflammatory Disorder ◽  
Anogenital Region ◽  
Short Courses ◽  
Term Monitoring

Lichen sclerosus (LS) is a chronic inflammatory disorder of the skin and mucosa, presenting to genitourinary physicians and dermatologists. It affects both sexes and all age groups. Although the exact aetiology is uncertain, genetic predisposition, infections and autoimmune factors have been implicated in its pathogenesis. Symptoms include pruritis and soreness, but asymptomatic presentations are not uncommon. The classical clinical picture is of atrophic white plaques in the anogenital region. Histopathology is specific with basal cell degeneration, upper dermal oedema, homogenization of collagen and a chronic inflammatory infiltrate. Short courses of potent topical corticosteroids form the mainstay of treatment. The condition tends to be remitting and relapsing, with spontaneous regressions reported in a few. In men, the term balanitis xerotica obliterans is sometimes used to describe late and severe LS of the penis. Scarring and progression to squamous cell carcinomas can occur in chronic LS, resulting in significant morbidity. A multi-disciplinary approach to care and the need for long-term monitoring cannot be over-emphasized.

scholarly journals A Case Report: The Effect of Thread Embedding Acupuncture on Partly-Controlled Asthma

2021 ◽  
Vol 7 (2) ◽  
pp. 104
Author(s):  
Yusuf Gunawan ◽  
Irma Nareswari ◽  
Irma Nareswari
Keyword(s):  
Case Report ◽  
Inflammatory Process ◽  
Complementary Therapies ◽  
Inflammatory Disorder ◽  
Control Test ◽  
Uncontrolled Asthma ◽  
Asthma Control Test ◽  
Chronic Inflammatory Disorder ◽  
Anti Inflammation

Asthma is a chronic inflammatory disorder of the respiratory tract where many cells and cellular elements play a role, especially eosinophils, IgE, and other components. Uncontrolled asthma causes the quality of the patient's life to decline. Acupuncture is one of the complementary therapies that are scientifically proven to help cure asthma. Many studies have proven that acupuncture plays a role in the anti-inflammatory process. In this case report, we used the acupuncture method of thread embedding penetration from point EX-B1 to BL13, LI11, ST36, and BL23 on both sides. Acupuncture therapy is done once when the patient first arrives. The results after 3 months observations showed that patients experienced an improvement in eosinophil count, decreased level of IgE, and increased Asthma Control Test values. The improvement showed patients were fully controlled in the first month until the end of the evaluation. Therefore, thread embedding could be a good, safe, and effective treatment for asthma in adults.Keywords: asthma, thread embedding acupuncture, anti-inflammation

scholarly journals Etiology, Clinical Features, and Diagnosis of Vulvar Lichen Sclerosus: A Scoping Review

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Nilanchali Singh ◽  
Prafull Ghatage
Keyword(s):  
Clinical Features ◽  
Scoping Review ◽  
English Language ◽  
Lichen Sclerosus ◽  
Published Data ◽  
Inflammatory Disorder ◽  
Lichen Sclerosus Et Atrophicus ◽  
Chronic Inflammatory Disorder ◽  
Study Selection ◽  
Vulvar Lichen Sclerosus

Objective. Vulvar lichen sclerosus (VLS) is a chronic inflammatory disorder, which affects women of all ages. With numerous controversies as regards to the nomenclature, diagnosis and its association with neoplastic conditions, we decided to conduct a scoping review on this subject. Data Source. A review protocol was developed, and the Knowledge Resource Services website was used to do a search of articles pertaining to VLS with keywords “Vulvar,” “Vulval,” “diagnosis,” “lichen sclerosus et atrophicus,” “kraurosis,” “vulvar dystrophy,” and “Lichen Sclerosus”. Study Selection. The search was limited to published data from the last ten years, i.e., from July 2009 onwards and in the English language. A total of 338 articles pertaining to VLS were obtained. Older data were accessed if particular information was sought for. Results & Conclusion. The presentation is bimodal, i.e., one in prepubertal girls (average age: 7.6 years) and the other in peri- and postmenopausal women (average age: 52.6 years). However, many cases also present during reproductive years. Studies suggest a multifactorial origin as far as etiology is concerned, including a genetic, autoimmune, hormonal, and local infectious background. It affects the genital labial, perineal, and perianal areas and manifests as a patchy, thin, glistening, ivory-white area. Diagnosis is mainly based on clinical features. Biopsy is seldom required. It has been well established as a precursor lesion of dVIN and vulvar carcinoma.

scholarly journals Kimura Disease: A Case Report and Review of the Literature with A New Management Protocol

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Mohamed Ashraf Fouda ◽  
Osama Gheith ◽  
Ayman Refaie ◽  
Mohamed El-Saeed ◽  
Adel Bakr ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Case Report ◽  
Membranous Glomerulonephritis ◽  
Inflammatory Disorder ◽  
Review Of The Literature ◽  
Kimura Disease ◽  
Chronic Inflammatory Disorder ◽  
Asian Race ◽  
Management Protocol ◽  
Atypical Manifestation

Kimura disease (KD) is a chronic inflammatory disorder with angiolymphatic proliferation, usually affecting young men of Asian race but is rare in other races. The etiology of KD is still unknown. It is often accompanied by nephrotic syndrome. Herein, we present an atypical manifestation of Kimura disease occurring in a Caucasian man with steroid-responsive early membranous glomerulonephritis. Kimura disease can present atypically in a middle-aged Caucasian man with secondary steroid-responsive nephrotic syndrome. Steroid, endoxan, and MMF can be used safely and successfully in such situation. The diagnosis of KD can be difficult and misleading, and patients with this disease are often evaluated using avoidable procedures by just not being aware of KD.

scholarly journals Ankylosing Spondylitis with Peripheral Neuropathy - A Rare Case Report

2016 ◽  
Vol 17 (1) ◽  
pp. 36-38
Author(s):  
Sarmistha Biswas ◽  
HAM Nazmul Ahasan ◽  
Prodip Kumar Biswas ◽  
Md Harun Ur Rashid ◽  
Prodip Kumar Sarkar ◽  
...  
Keyword(s):  
Case Report ◽  
Ankylosing Spondylitis ◽  
Peripheral Neuropathy ◽  
Rare Case ◽  
Neurological Complication ◽  
Inflammatory Disorder ◽  
Sacroiliac Joints ◽  
Chronic Inflammatory Disorder ◽  
Rare Case Report

Ankylosing Spondylosis (AS) is a chronic inflammatory disorder of joints predominantly affecting the sacroiliac joints and spine. Besides the joints, it affects many extra articular sites like heart, eye, lungs etc. Neurological complication is very rare in AS. Here we report a case of a 30 years old man of AS with peripheral neuropathy.J MEDICINE January 2016; 17 (1) : 36-38

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