scholarly journals Procedural Pediatric Sedation by Nurses: Available, Competent, and Safe

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Laetiscia Lavoie ◽  
Catherine Vezina ◽  
Emilie Paul-Savoie ◽  
Claude Cyr ◽  
Sylvie Lafrenaye
Keyword(s):  
Retrospective Study ◽  
Pediatric Patients ◽  
Standard Of Care ◽  
Centre Hospitalier ◽  
Major Complications ◽  
Centre Hospitalier Universitaire ◽  
Pediatric Sedation ◽  
One Year ◽  
Physician Availability ◽  
Sedation Program

Sedation and/or analgesia are standard of care for pediatric patients during painful intervention or medical imaging requiring immobility. Physician availability is frequently insufficient to allow for all procedural sedation. A nurse-led sedation program was created at the Centre Hospitalier Universitaire de Sherbrooke (CHUS) to address this problem.Objective. To evaluate the effectiveness and the safety of our program.Methods. A retrospective study of all the procedural sedations done over one year was performed. Complications were separated in four categories: (1) major complications (call for help; unexpected admission, aspiration, and code); (2) reportable sedation events (oxygen saturation <90%, bradycardia (more than 2 SD below normal for the age of the child), and hypotension (more than 2 SD below normal for the age of the child); (3) difficult sedation (agitation, inadequate sedation, and failure to perform the procedure), (4) minor complications.Results. 448 patients, 249 boys and 199 girls; received sedation for 555 procedures. Overall, 78% (432) of interventions were successfully accomplished: 0% of major complications, 8% of reportable sedation events; 5% of difficult sedation; 9% of minor complications.Conclusion. Our nurse-led sedation program compares favorably to other similar systems.

HOW TOPICAL BETA-BLOCKER DID WONDER IN THE MANAGEMENT OF RESIDUAL HEMANGIOMA AFTER PROPRANOLOL THERAPY

2021 ◽  
pp. 44-46
Author(s):  
Zaheer hasan ◽  
Vinit kumar Thakur ◽  
Rakesh kumar ◽  
Digamber chaubey ◽  
Rupesh keshri
Keyword(s):  
Retrospective Study ◽  
Side Effects ◽  
Beta Blocker ◽  
Complete Resolution ◽  
Pediatric Patients ◽  
Β Blocker ◽  
One Year ◽  
Propranolol Therapy ◽  
Therapy Result

Background: To determine the role of topical β- blocker in the management of residual hemangioma after propranolol therapy. Method: A retrospective study of all pediatric patients presenting with hemangioma from April 2014 to March 2019 was performed. Topical timolol gel was applied over the residual hemangioma which persisted even after one year of propranolol therapy. Result: Out of 68 patients included in this study 45 (70.3%), patients had complete resolution by one year using the treatment with propranolol. In 14 patients (21.8%) had residual lesion even after 1 year of treatment, upon which we applied topical timolol 0.5% gel for further 4 to 6 months. (Mean 5.35 months). At the end of the treatment, hemangioma was almost resolved. Conclusion: Timolol is a safer alternative to propranolol for residual hemangioma as a sequential treatment. It augments the regression of residual hemangioma with minimal side effects.

A Clinical Study and Management of Inguino-scrotal Swellings In Children

2018 ◽  
Vol 2 (S1) ◽  
pp. e000125
Author(s):  
Khyati Vaja ◽  
Mukesh Suvera
Keyword(s):  
Inguinal Hernia ◽  
Pediatric Surgery ◽  
Pediatric Patients ◽  
Undescended Testis ◽  
Length Of Hospital Stay ◽  
Indirect Inguinal Hernia ◽  
Short Term ◽  
One Year ◽  
Groin Hernias ◽  
Inguinal Hernia In Children

Aims and Objectives: To know the most common surgical problems in pediatric patients presented with inguino-scrotal swellings and management done routinely. Methodology: This study was carried out in the department of general surgery, Sharadaben hospital and pediatric surgery of VS hospital, Ahmedabad. The cases were studied for a period of about one year (January, 2017 to Dec, 2017) and all children below 12 years of age, presenting to us with inguinoscrotal swellings were included in this study. The information was analysed in terms of age, diagnosis, procedure carried out and outcome. Results: Amongst the 150 children under the age of 12 years, 143 patients were males and 7 were females. Among these 150, 52 cases were of hydrocoele, 70 cases of hernia (of which 63 were males and 7 were females), 25 cases of undescended testis and 3 cases of epididymo orchitis were documented. All cases underwent simple herniotomy for hernia and hydrocoele, orchidopexy for undescended testis. The length of hospital stay ranged from 2-4 days with mean of 2.46 days. 11 children in the study were documented to have short term complications, all of which were recognised in the hospital and managed with good results. Conclusion: Hernia and Hydrocoele in children are often congenital and diagnosed clinically (history and examination). Indirect inguinal hernia are more common than other groin hernias. Open herniotomy is the operation of choice for inguinal hernia in children.

Les aires d'influence d'un Centre Hospitalier Universitaire (C.H.U.) : l'exemple angevin

Norois ◽  
1999 ◽  
Vol 182 (2) ◽  
pp. 303-317
Author(s):  
Sébastien Fleuret ◽  
Vincent Veschambre
Keyword(s):  
Centre Hospitalier ◽  
Centre Hospitalier Universitaire

Aspects épidémiologiques, cliniques et évolutifs des traumatisés graves admis en réanimation polyvalente du Centre Hospitalier Universitaire de Brazzaville, République du Congo

2020 ◽  
Author(s):  
Gilbert Fabrice Otiobanda ◽  
Christ Mayick Mpoy Emy Monkessa ◽  
Marie Elombila ◽  
Hugues Brieux Ekouele Mbaki ◽  
Gilles Niengo Outsouta ◽  
...  
Keyword(s):  
Sex Ratio ◽  
Centre Hospitalier ◽  
Taux De Mortalité ◽  
Centre Hospitalier Universitaire ◽  
Cause De Décès ◽  
Détresse Respiratoire ◽  
Congo Brazzaville

Contexte : Le traumatisé grave (TG) est un patient ayant subi un traumatisme violent quelles que soient les lésions apparentes. Aucune donnée épidémiologique n’a été retrouvée au Congo-Brazzaville. L’objectif était de décrire les aspects épidémiologiques, cliniques et évolutifs des TG au CHU de Brazzaville (CHU-B). Matériels et méthodes : L’étude était rétrospective en 30 mois sur 82 TG en réanimation. Les variables épidémiologiques, cliniques et évolutives étaient analysées sur Excel 2016. Résultats : L’âge moyen était de 37,2 ± 16,4 ans (sex-ratio : 4,1). Les patients étaient transférés des urgences dans 48,8 %. Les accidents de la voie publique (82,9 %) constituaient la circonstance traumatique la plus fréquente. Le Glasgow moyen était de 10,1 ± 4,1. La détresse respiratoire et l’état de choc étaient respectivement observés dans 35,4 % et 17,1 %. La tête (76,8 %) et le thorax (41,5 %) étaient les régions les plus touchées. Les complications étaient retrouvées dans 34,1 %. Le taux de mortalité était de 42,7 %. La détresse neurologique (62,9 %) était la principale cause de décès. La durée médiane d’hospitalisation était de 5 jours. Conclusion : Le TG occupe 5,7 % des admissions en réanimation. Il touche une population juvénile masculine victime d’AVP. La tête et le thorax étaient les plus touchés. La mortalité est très élevée.

scholarly journals Current FDA-Approved Therapies for High-Grade Malignant Gliomas

Biomedicines ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 324
Author(s):  
Jacob P. Fisher ◽  
David C. Adamson
Keyword(s):  
Controlled Trial ◽  
Malignant Gliomas ◽  
Progression Free Survival ◽  
Standard Of Care ◽  
High Grade ◽  
Tumor Treatment ◽  
Free Survival ◽  
Randomized Controlled ◽  
Significant Survival ◽  
One Year

The standard of care (SOC) for high-grade gliomas (HGG) is maximally safe surgical resection, followed by concurrent radiation therapy (RT) and temozolomide (TMZ) for 6 weeks, then adjuvant TMZ for 6 months. Before this SOC was established, glioblastoma (GBM) patients typically lived for less than one year after diagnosis, and no adjuvant chemotherapy had demonstrated significant survival benefits compared with radiation alone. In 2005, the Stupp et al. randomized controlled trial (RCT) on newly diagnosed GBM patients concluded that RT plus TMZ compared to RT alone significantly improved overall survival (OS) (14.6 vs. 12.1 months) and progression-free survival (PFS) at 6 months (PFS6) (53.9% vs. 36.4%). Outside of TMZ, there are four drugs and one device FDA-approved for the treatment of HGGs: lomustine, intravenous carmustine, carmustine wafer implants, bevacizumab (BVZ), and tumor treatment fields (TTFields). These treatments are now mainly used to treat recurrent HGGs and symptoms. TTFields is the only treatment that has been shown to improve OS (20.5 vs. 15.6 months) and PFS6 (56% vs. 37%) in comparison to the current SOC. TTFields is the newest addition to this list of FDA-approved treatments, but has not been universally accepted yet as part of SOC.

scholarly journals Parasitic infections in Swiss children: Are we overtesting?

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Corinne Légeret ◽  
Céline Rüttimann ◽  
Hans Fankhauser ◽  
Henrik Köhler
Keyword(s):  
Retrospective Study ◽  
Positive Result ◽  
Pediatric Patients ◽  
Intestinal Parasites ◽  
Gastrointestinal Symptoms ◽  
International Travel ◽  
Parasitic Infections ◽  
Stool Samples ◽  
Stool Specimens

Abstract Background A wide variation of causes can lead to gastrointestinal symptoms in children- an infection with parasites is one of them. The expansion of international travel might lead to an increase in testing children for a correspondent infection. Currently there are no guidelines available, which patients should be tested for a possible parasitical infection. The aim of the study was to characterize Swiss children suffering from intestinal parasites, in order to provide more knowledge for the clinician who should be tested. Methods This is a retrospective study of Swiss pediatric patients, whose stools have been tested for parasites and helminths. Results A total of 1855 stool samples, belonging to 572 different children with an average age of 7.9 years, were tested within a 10-year period. The prevalence of a positive result was 4.2%, of which all were positive for Blastocystis, and 12.5% had a co-infection with Endolimax nana. Conclusion Immigrants, immune compromised children with diarrhea and pediatric patients with bloody or protracted diarrhea should have 2 different stool specimens examined for a possible parasitical infection.

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