scholarly journals Intracranial Blood Flow Velocity in Patients withβ-Thalassemia Intermedia Using Transcranial Doppler Sonography: A Case-Control Study

Anemia ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Nahid Ashjazadeh ◽  
Sajad Emami ◽  
Peyman Petramfar ◽  
Ehsan Yaghoubi ◽  
Mehran Karimi
Keyword(s):  
Blood Flow ◽  
Transcranial Doppler ◽  
Healthy Subjects ◽  
Doppler Sonography ◽  
Transcranial Doppler Sonography ◽  
Arterial Blood Flow ◽  
Thalassemia Intermedia ◽  
Arterial Blood ◽  
Ischemic Events ◽  
Flow Velocities

Introduction. Patients withβ-thalassemia intermedia have a higher incidence of thromboembolic events compared to the general population. Previous studies have shown that patients with sickle cell disease, who are also prone to ischemic events, have higher intracranial arterial blood flow velocities measured by transcranial Doppler sonography (TCD). The aim of this study is to evaluate intracranial arterial flow velocities in patients withβ-thalassemia intermedia and compare the results with those found in healthy subjects.Methods. Sixty-four patients withβ-thalassemia intermedia and 30 healthy subjects underwent transcranial Doppler sonography.Results. Significantly higher flow velocities were found in intracranial arteries of patients compared to controls (P=0.001). Previously splenectomized patients with thrombocytosis showed higher flow velocities than nonsplenectomized patients without thrombosis.Conclusion. The increased flow velocities in patients withβ-thalassemia intermedia may point to a higher risk of ischemic events. Preventive measures such as blood transfusion or antiplatelet treatment may be beneficial in these patients.

Transcranial Doppler Sonography in Children

1989 ◽  
Vol 4 (1_suppl) ◽  
pp. S68-S76 ◽  
Author(s):  
Harald Bode ◽  
Alec Eden
Keyword(s):  
Transcranial Doppler ◽  
Doppler Sonography ◽  
Extreme Values ◽  
Ductus Arteriosus ◽  
Cerebral Arteries ◽  
Transcranial Doppler Sonography ◽  
Stable State ◽  
Carbon Dioxide Partial Pressure ◽  
Arterial Blood ◽  
Flow Velocities

The blood flow velocities in the basal cerebral arteries can be recorded at any age by transcranial Doppler sonography. By a standardized examination technique, the vessel identification is reliable even without visual control of the site of the sample volume. A stable state of vigilance is necessary to obtain constant recordings. Age has a tremendous influence on the flow velocities. The velocities increase rapidly during the first weeks and reach their maximum around the sixth year of life. The influence of carbon dioxide partial pressure, gestational age, birth weight, hematocrit, and vigilance on the velocities has to be considered. Heart rate and arterial blood pressure are relevant only in cases of extreme values. The clinical applications of transcranial Doppler sonography cover diseases like patent ductus arteriosus, perinatal brain damage, increased intracranial pressure, cerebral malformations, brain death, and stenoses and occlusions of main cerebral arteries. The technique is helpful for control of certain therapies. A continuous recording technique has also been developed for this purpose. Care should be taken in deriving a prognosis from Doppler recordings. (J Child Neurol 1989;4:S68-S76).

Hepatic arterial blood flow velocities: assessment by transcutaneous and intravascular Doppler sonography

2000 ◽  
Vol 32 (6) ◽  
pp. 893-899 ◽  
Author(s):  
Georg H Hübner ◽  
Norbert Steudel ◽  
Gerhard Kleber ◽  
Curt Behrmann ◽  
Erich Lotterer ◽  
...  
Keyword(s):  
Blood Flow ◽  
Doppler Sonography ◽  
Arterial Blood Flow ◽  
Hepatic Arterial Blood Flow ◽  
Arterial Blood ◽  
Blood Flow Velocities ◽  
Flow Velocities

Patterns of Cerebral Blood Flow and Systemic Hemodynamics During Arithmetic Processing

2008 ◽  
Vol 22 (2) ◽  
pp. 81-90 ◽  
Author(s):  
Natalie Werner ◽  
Neval Kapan ◽  
Gustavo A. Reyes del Paso
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Time Course ◽  
Doppler Sonography ◽  
Transcranial Doppler Sonography ◽  
Systemic Hemodynamics ◽  
Heart Period ◽  
Blood Flow Velocities ◽  
Flow Velocities

The present study explored modulations in cerebral blood flow and systemic hemodynamics during the execution of a mental calculation task in 41 healthy subjects. Time course and lateralization of blood flow velocities in the medial cerebral arteries of both hemispheres were assessed using functional transcranial Doppler sonography. Indices of systemic hemodynamics were obtained using continuous blood pressure recordings. Doppler sonography revealed a biphasic left dominant rise in cerebral blood flow velocities during task execution. Systemic blood pressure increased, whereas heart period, heart period variability, and baroreflex sensitivity declined. Blood pressure and heart period proved predictive of the magnitude of the cerebral blood flow response, particularly of its initial component. Various physiological mechanisms may be assumed to be involved in cardiovascular adjustment to cognitive demands. While specific contributions of the sympathetic and parasympathetic systems may account for the observed pattern of systemic hemodynamics, flow metabolism coupling, fast neurogenic vasodilation, and cerebral autoregulation may be involved in mediating cerebral blood flow modulations. Furthermore, during conditions of high cardiovascular reactivity, systemic hemodynamic changes exert a marked influence on cerebral blood perfusion.

scholarly journals Renal arterial blood flow measurement by breath-held MRI: Accuracy in phantom scans and reproducibility in healthy subjects

2010 ◽  
Vol 63 (4) ◽  
pp. 940-950 ◽  
Author(s):  
Samuel Dambreville ◽  
Arlene B. Chapman ◽  
Vicente E. Torres ◽  
Bernard F. King ◽  
Ashley K. Wallin ◽  
...  
Keyword(s):  
Blood Flow ◽  
Healthy Subjects ◽  
Flow Measurement ◽  
Arterial Blood Flow ◽  
Blood Flow Measurement ◽  
Arterial Blood

Transesophageal Doppler Measurement of Renal Arterial Blood Flow Velocities and Indices in Children

2012 ◽  
Vol 114 (6) ◽  
pp. 1277-1284 ◽  
Author(s):  
Luis Zabala ◽  
Sana Ullah ◽  
Carol DʼAnn Pierce ◽  
Nischal K. Gautam ◽  
Michael L. Schmitz ◽  
...  
Keyword(s):  
Blood Flow ◽  
Arterial Blood Flow ◽  
Doppler Measurement ◽  
Arterial Blood ◽  
Blood Flow Velocities ◽  
Transesophageal Doppler ◽  
Flow Velocities
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