Assessment of blood flow velocities in the ophthalmic arteries by transcranial Doppler sonography in osteopetrosis

1997 ◽  
Vol 13 (2) ◽  
pp. 113-117 ◽  
Author(s):  
J. Iqbal
2008 ◽  
Vol 22 (2) ◽  
pp. 81-90 ◽  
Author(s):  
Natalie Werner ◽  
Neval Kapan ◽  
Gustavo A. Reyes del Paso

The present study explored modulations in cerebral blood flow and systemic hemodynamics during the execution of a mental calculation task in 41 healthy subjects. Time course and lateralization of blood flow velocities in the medial cerebral arteries of both hemispheres were assessed using functional transcranial Doppler sonography. Indices of systemic hemodynamics were obtained using continuous blood pressure recordings. Doppler sonography revealed a biphasic left dominant rise in cerebral blood flow velocities during task execution. Systemic blood pressure increased, whereas heart period, heart period variability, and baroreflex sensitivity declined. Blood pressure and heart period proved predictive of the magnitude of the cerebral blood flow response, particularly of its initial component. Various physiological mechanisms may be assumed to be involved in cardiovascular adjustment to cognitive demands. While specific contributions of the sympathetic and parasympathetic systems may account for the observed pattern of systemic hemodynamics, flow metabolism coupling, fast neurogenic vasodilation, and cerebral autoregulation may be involved in mediating cerebral blood flow modulations. Furthermore, during conditions of high cardiovascular reactivity, systemic hemodynamic changes exert a marked influence on cerebral blood perfusion.


Anemia ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Nahid Ashjazadeh ◽  
Sajad Emami ◽  
Peyman Petramfar ◽  
Ehsan Yaghoubi ◽  
Mehran Karimi

Introduction. Patients withβ-thalassemia intermedia have a higher incidence of thromboembolic events compared to the general population. Previous studies have shown that patients with sickle cell disease, who are also prone to ischemic events, have higher intracranial arterial blood flow velocities measured by transcranial Doppler sonography (TCD). The aim of this study is to evaluate intracranial arterial flow velocities in patients withβ-thalassemia intermedia and compare the results with those found in healthy subjects.Methods. Sixty-four patients withβ-thalassemia intermedia and 30 healthy subjects underwent transcranial Doppler sonography.Results. Significantly higher flow velocities were found in intracranial arteries of patients compared to controls (P=0.001). Previously splenectomized patients with thrombocytosis showed higher flow velocities than nonsplenectomized patients without thrombosis.Conclusion. The increased flow velocities in patients withβ-thalassemia intermedia may point to a higher risk of ischemic events. Preventive measures such as blood transfusion or antiplatelet treatment may be beneficial in these patients.


1989 ◽  
Vol 70 (5) ◽  
pp. 732-736 ◽  
Author(s):  
Bertil Romner ◽  
Bengt Ljunggren ◽  
Lennart Brandt ◽  
Hans Säveland

✓ Twenty-one patients were subjected to repeated assessment of cerebral blood flow velocities by means of transcranial Doppler sonography (TCDS) during the first 12 hours after subarachnoid hemorrhage (SAH). In 19 patients the study was performed following the first SAH, and in two after early rebleeds. Flow velocities did not indicate an early phase of arterial narrowing in any case. Following the first TCDS assessment, flows were evaluated repeatedly in the 19 survivors. Increased flow velocities suggesting arterial narrowing or vasospasm occurred only after a delay of at least 4 days. The results of this study favor the restoration of normal velocity patterns in surviving patients and do not indicate that an acute phase of vasospasm exists either immediately after or in the first 12 hours after SAH.


1992 ◽  
Vol 77 (Supplement) ◽  
pp. A165
Author(s):  
P. Brauer ◽  
W. A. Kofke ◽  
C. Werner ◽  
E. Kochs ◽  
M. Bloom ◽  
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