scholarly journals Hydroxyapatite Coating of Titanium Implants Using Hydroprocessing and Evaluation of Their Osteoconductivity

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Kensuke Kuroda ◽  
Masazumi Okido

Many techniques for the surface modification of titanium and its alloys have been proposed from the viewpoint of improving bioactivity. This paper contains an overview of surface treatment methods, including coating with hydroxyapatite (HAp), an osteoconductive compound. There are two types of coating methods: pyroprocessing and hydroprocessing. In this paper, hydroprocessing for coating on the titanium substrate with HAp, carbonate apatite (CO3–Ap), a CO3–Ap/CaCO3composite, HAp/collagen, and a HAp/gelatin composite is outlined. Moreover, evaluation by implantation of surface-modified samples in rat tibiae is described.

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Yao Shu ◽  
Guomin Ou ◽  
Li Wang ◽  
Jingcai Zou ◽  
Quanli Li

Extracellular matrix (ECM), like biomimetic surface modification of titanium implants, is a promising method for improving its biocompatibility. In this paper chitosan (Chi) and heparin (Hep) multilayer was coated on pure titanium using a layer-by-layer (LbL) self-assembly technique. The Hep-Chi multilayer growth was carried out by first depositing a single layer of positively charged poly-L-lysine (PLL) on the NaOH-treated titanium substrate (negatively charged surface), followed by alternate deposition of negatively charged Hep and positively charged Chi, and terminated by an outermost layer of Chi. The multilayer was characterized by DR-FTIR, SEM, and AFM, and osteoblasts were cocultured with the modified titanium and untreated titanium surfaces, respectively, to evaluate their cytocompatibilityin vitro. The results confirmed that Hep-Chi multilayer was fabricated gradually on the titanium surface. The Hep-Chi multilayer-coated titanium improved the adhesion, proliferation and differentiation of osteoblasts. Thus, the approach described here may provide a basis for the preparation of modified titanium surfaces for use in dental or orthopedic implants.


Nanoscale ◽  
2015 ◽  
Vol 7 (21) ◽  
pp. 9908-9918 ◽  
Author(s):  
Elisabeth Rieger ◽  
Agnès Dupret-Bories ◽  
Laetitia Salou ◽  
Marie-Helene Metz-Boutigue ◽  
Pierre Layrolle ◽  
...  

Nanoscale surface modification of titanium microbeads can control the soft tissue response in vitro and in vivo.


Author(s):  
Mohini Gajiwala ◽  
Jyoti Paliwal ◽  
Syed Yawer Husain ◽  
Ashish Dadarwal ◽  
Rajni Kalla ◽  
...  

2007 ◽  
Vol 18 (12) ◽  
pp. 2291-2296 ◽  
Author(s):  
Garrit Koller ◽  
Richard J. Cook ◽  
Ian D. Thompson ◽  
Timothy F. Watson ◽  
Lucy Di Silvio

2009 ◽  
Vol 20 (4) ◽  
pp. 710-718 ◽  
Author(s):  
Jan Michael ◽  
Lena Schönzart ◽  
Ina Israel ◽  
René Beutner ◽  
Dieter Scharnweber ◽  
...  

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