scholarly journals Mucormycosis of Mandible with Unfavorable Outcome

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Nitin Prakash Oswal ◽  
Pushkar Kiran Gadre ◽  
Prachee Sathe ◽  
Kiran Shrikrishna Gadre
Keyword(s):  
Diabetes Mellitus ◽  
Treatment Approach ◽  
Rare Complication ◽  
Multimodality Treatment ◽  
Poor Survival ◽  
Radiographic Diagnosis ◽  
Uncontrolled Diabetes ◽  
Fungal Hyphae ◽  
Histopathological Evaluation ◽  
Definitive Management

Mucormycosis is a fulminant fungal infection that occurs most often in diabetic and immunocompromised individuals. Our patient, with uncontrolled diabetes mellitus and multiple systemic disorders, developed postextraction mucormycosis of mandible, an extremely rare complication. An initial clinical and radiographic diagnosis of mandibular osteomyelitis was made and the lesion was treated medically and surgically with curettage and saucerisation. The specimen was sent for histopathological evaluation, which showed necrotic area containing broad aseptate fungal hyphae with right angle branching consistent with mucormycosis. The patient succumbed to multipleorgan failure secondary to septicemia. The disease is usually fatal with a poor survival rate; there is still paucity of literature on the definitive management of this disease involving the mandible. This paper emphasizes the need for correction of underlying immunodeficiency and early diagnosis with aggressive multimodality treatment approach to offer the best chance of survival.

scholarly journals Mucormycosis- in a case of diabetes mellitus

2017 ◽  
Vol 5 (5) ◽  
pp. 2248
Author(s):  
Felin Ann Francis ◽  
Varun Shetty ◽  
Amit Khomne ◽  
Imran Ansari
Keyword(s):  
Diabetes Mellitus ◽  
Fungal Infection ◽  
Diabetic Ketoacidosis ◽  
Diagnostic Technique ◽  
Final Diagnosis ◽  
Orbital Cellulitis ◽  
Mri Brain ◽  
Uncontrolled Diabetes ◽  
Fungal Hyphae ◽  
Nasal Biopsy

Mucormycosis is a rare fungal infection seen in immunocompromised people especially with uncontrolled diabetes mellitus – in this case causing orbital cellulitis. Patient of diabetic ketoacidosis was investigated with CT PNS, MRI Brain and Final diagnosis was made after clinical examination, discussion with ENT specialist, ophthalmologist about the best diagnostic technique and an endoscopic nasal biopsy was done - which showed fungal hyphae.

scholarly journals Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Lima Lawrence ◽  
Oscar Tovar-Camargo ◽  
M. Cecilia Lansang ◽  
Vinni Makin
Keyword(s):  
Diabetes Mellitus ◽  
Rare Complication ◽  
Acute Onset ◽  
Muscular Pain ◽  
Uncontrolled Diabetes ◽  
Long Term Prognosis ◽  
The Right ◽  
High Index Of Suspicion ◽  
Microvascular And Macrovascular Complications

Objective. Diabetes mellitus is associated with microvascular and macrovascular complications; the most commonly recognized ones include diabetic nephropathy, retinopathy, and neuropathy. Less well-known complications are equally important, as timely recognition and treatment are essential to decrease short- and long-term morbidity. Methods. Herein, we describe a case of a 41-year-old female with longstanding, uncontrolled type 2 diabetes, who presented with classical findings of diabetic myonecrosis. Results. Our patient underwent extensive laboratory and imaging studies prior to diagnosis due to its rarity and similarity in presentation with other commonly noted musculoskeletal conditions. We emphasize the clinical presentation, laboratory and imaging findings, treatment regimen, and prognosis associated with diabetic myonecrosis. Conclusion. Diabetic myonecrosis is a rare complication of longstanding, poorly controlled diabetes mellitus. The diagnosis requires a high index of suspicion in the right clinical setting: acute onset nontraumatic muscular pain with associated findings on clinical exam, laboratory studies, and imaging. While the short-term prognosis is good, the recurrence rate remains high and long-term prognosis is poor given underlying uncontrolled diabetes and associated sequelae.

scholarly journals Twin presentation of rhinocerebral mucormycosis and parotid abscess with facial nerve palsy in a case of unrevealed uncontrolled diabetes mellitus

2021 ◽  
Vol 7 (6) ◽  
pp. 1052
Author(s):  
Preeti S. Shetti ◽  
Reshma R. ◽  
Prasheetha B. ◽  
O. Padmavathy
Keyword(s):  
Diabetes Mellitus ◽  
Facial Nerve ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Rare Complication ◽  
Rhinocerebral Mucormycosis ◽  
Ascending Infection ◽  
Parotid Duct ◽  
Uncontrolled Diabetes ◽  
The One

<p class="abstract">Rhinocerebral mucormycosis is a saprophytic invasive fungal infection of the nose and paranasal sinuses. The angio-invasive nature of the disease and rapid spread to the surrounding vital structures makes this infection more fatal. Parotid abscess is a rare disease in both adults and children due to an ascending infection from the oral cavity via the parotid duct. Diabetes mellitus is an immuno-compromised state in which patients are more prone for several infections. Both these diseases can lead to fatal complications due to their spread and toxicity, but the one rare complication of both these diseases is Facial nerve palsy. We are presenting a case of Diabetes mellitus with Rhinocerebral mucormycosis and Parotid abscess. There have been very few documented cases of co-existing Rhinocerebral mucormycosis and Parotid abscess in a patient with facial nerve palsy as complication.</p>

scholarly journals A Rare and Lethal Complication: Cerebral Edema in the Adult Patient with Diabetic Ketoacidosis

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Christopher W. Meaden ◽  
Beth J. Kushner ◽  
Stacey Barnes
Keyword(s):  
Diabetes Mellitus ◽  
Emergency Department ◽  
Case Report ◽  
Diabetic Ketoacidosis ◽  
Cerebral Edema ◽  
Rare Complication ◽  
Adult Population ◽  
Uncontrolled Diabetes ◽  
New Onset Diabetes Mellitus ◽  
New Onset

Commonly seen in the emergency department, diabetic ketoacidosis is a potentially lethal sequela of uncontrolled diabetes mellitus. In the adult population, a rare complication of diabetic ketoacidosis is cerebral edema. This case report discusses a 26-year-old male with new onset diabetes mellitus who developed cerebral edema leading to death.

scholarly journals Comprehensive Literature Review: Recent Advances in Diagnosing and Managing Patients with Poorly Differentiated Thyroid Carcinoma

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Jack Hannallah ◽  
Jessica Rose ◽  
Marlon A. Guerrero
Keyword(s):  
Treatment Approach ◽  
Survival Rates ◽  
Multimodality Treatment ◽  
Differentiated Thyroid Carcinoma ◽  
Poor Survival ◽  
Thyroid Carcinomas ◽  
Comprehensive Literature Review ◽  
Poorly Differentiated ◽  
Well Differentiated ◽  
Therapeutic Tools

Poorly differentiated thyroid carcinomas are a rare form of thyroid carcinomas; they display an intermediate behavior between well-differentiated and anaplastic thyroid carcinomas. PDTCs are more aggressive than the well-differentiated, but less aggressive than the undifferentiated or anaplastic, forms. No clinical features can accurately diagnose poorly differentiated thyroid carcinomas. Thus, the results of histocytology, immunohistochemistry, and molecular genetics tests aid in diagnosis. Given the aggressiveness of poorly differentiated thyroid carcinomas and the poor survival rates in patients who undergo surgery alone, a multimodality treatment approach is required. We conducted a comprehensive review of the current diagnostic and therapeutic tools in the management of patients with poorly differentiated thyroid carcinomas.

Nonketotic Hyperglycemic Chorea in a 10-Year-Old Asian Boy with Diabetes Mellitus

2020 ◽  
Author(s):  
Julia Marian ◽  
Firdous Rizvi ◽  
Lily Q. Lew
Keyword(s):  
Diabetes Mellitus ◽  
Parietal Lobe ◽  
Rare Complication ◽  
Brain Magnetic Resonance Imaging ◽  
Food Allergies ◽  
Developmental Venous Anomaly ◽  
Venous Anomaly ◽  
Resonance Imaging ◽  
Focal Lesions

AbstractNonketotic hyperglycemic chorea-ballism (NKHCB), also known as diabetic striato-pathy (DS) by some, is a rare complication of diabetes mellitus and uncommon in children. We report a case of a 10 11/12-year-old boy of Asian descent with uncontrolled type 1 diabetes mellitus (T1DM), Hashimoto's thyroiditis, and multiple food allergies presenting with bilateral chorea-ballism. His brain magnetic resonance imaging revealed developmental venous anomaly in right parietal lobe and right cerebellum, no focal lesions or abnormal enhancements. Choreiform movements resolved with correction of hyperglycemia. Children and adolescents with a movement disorder should be evaluated for diabetes mellitus, especially with increasing prevalence and insidious nature of T2DM associated with obesity.

Plasma vasopressin in uncontrolled diabetes mellitus

Diabetes ◽  
1979 ◽  
Vol 28 (5) ◽  
pp. 503-508 ◽  
Author(s):  
R. L. Zerbe ◽  
F. Vinicor ◽  
G. L. Robertson
Keyword(s):  
Diabetes Mellitus ◽  
Plasma Vasopressin ◽  
Uncontrolled Diabetes

The Role of Diabetes Mellitus in Diseases of the Gallbladder and Biliary Tract

2020 ◽  
Vol 16 (9) ◽  
pp. 931-948
Author(s):  
Benjamin Rahmani ◽  
Jason Gandhi ◽  
Gunjan Joshi ◽  
Noel L. Smith ◽  
Inefta Reid ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Diabetic Neuropathy ◽  
Gallbladder Cancer ◽  
Biliary Tract ◽  
Treatment Approach ◽  
Database Search ◽  
Heavy Burden ◽  
Prevalence Of Diabetes Mellitus

Background: The increasing prevalence of diabetes mellitus worldwide continues to pose a heavy burden. Though its gastrointestinal impact is appropriately recognized, the lesser known associations may be overlooked. Objective: We aim to review the negative implications of diabetes on the gallbladder and the biliary tract. Methods: A MEDLINE® database search of literature was conducted with emphasis on the previous five years, combining keywords such as "diabetes," "gallbladder," and "biliary". Results: The association of diabetes to the formation of gallstones, gallbladder cancer, and cancer of the biliary tract are discussed along with diagnosis and treatment. Conclusion: Though we uncover the role of diabetic neuropathy in gallbladder and biliary complications, the specific individual diabetic risk factors behind these developments is unclear. Also, in addition to diabetes control and surgical gallbladder management, the treatment approach also requires further focus.

Association Between Awareness of Informal Caregivers and Falls in Elderly Patients with Uncontrolled Diabetes Mellitus

2020 ◽  
Vol 13 (1) ◽  
pp. 658-666
Author(s):  
Tossapon Chamnankit ◽  
Parichat Ong-artborirak ◽  
Jukkrit Wangrath
Keyword(s):  
Diabetes Mellitus ◽  
Elderly Patients ◽  
Elderly People ◽  
Informal Caregivers ◽  
Multivariable Analysis ◽  
P Value ◽  
Uncontrolled Diabetes ◽  
Risk Of Falls ◽  
The Mean ◽  
Falls In Elderly

Background: Elderly people with uncontrolled diabetes mellitus (DM) are at risk of falls, which can lead to injury and disability. Not much is known of informal caregivers’ awareness of falls in elderly patients with DM. Objective: This study aims to identify an association between caregiver’s awareness and falls in elderly patients with DM. Methods: A total of 136 pairs of DM patients and their respective family caregivers were recruited from a clinical service center at Chiang Mai University, Thailand. The questionnaire regarding the caregiver’s awareness of the risk of falls in elderly patients was given via a face-to-face interview. Each elderly patient was asked about their history of falls in the prior year, and the risk of falls was assessed by Time Up & Go (TUG) test. Logistic regression analysis was performed to determine association. Results: The mean age of the DM patients was 65.7 years. Sixty-two patients (45.6%) had fallen at least once in the prior year. The mean TUG test result was 12.67±1.83 second. Most caregivers demonstrated a high level of awareness regarding the risk of falls in elderly patients. The results of the multivariable analysis showed that three variables – balance problems, risk of falls assessed by TUG test, and scores of caregiver’s awareness of risk of falls – were significantly related to falls in the previous year among elderly patients with DM (p-value<0.05). Conclusion: The caregivers’ awareness of fall risk may influence fall occurrence among older adults with DM. An intervention program to improve awareness among informal caregivers should be considered for fall prevention in elderly people.

Sign in / Sign up

Export Citation Format

Share Document