scholarly journals CdTe Quantum dots Modified by Polyamidoamine Dendrimers for Cell Imaging

2012 ◽  
Vol 9 (1) ◽  
pp. 171-174 ◽  
Author(s):  
Jun'An Liu ◽  
Xiaolei Wei ◽  
Jianhua Cao ◽  
Hong Jiang

Water soluble CdTe quantum dots have shown potential as a platform for development of live cell imaging, but their cytotoxicity limits their biological applications. To decrease their cytotoxicity, an approach to modify CdTe quantum dots (QDs) with polyamidoamine (PAMAM) was employed by forming covalent bonds between them. The resultant nanocomposites as a cell imaging bioprobe for live PK15 and their in vitro toxicity were also investigated. The results showed that the prepared nanocomposites were able to enter PK15 cells with good biocompatibility and low cellular toxicity.

Molecules ◽  
2019 ◽  
Vol 24 (19) ◽  
pp. 3465
Author(s):  
Hio Kuan Lao ◽  
Jingyun Tan ◽  
Chunfei Wang ◽  
Xuanjun Zhang

Peroxynitrite (ONOO−) is one of the sources of oxidation stress involved in many biological signaling pathways. The role of ONOO− being a double-edged sword in biological systems drives the development of effective detection tools. In this work, a boronate-based polymeric fluorescent probe PB-PVA was synthesized and the probe performance was evaluated. The probe exhibits ratiometric sensing of ONOO− in a range of 0–6 µM. There is good linear relationship between the probe fluorescence intensity ratio and ONOO− concentration. The probe also displays moderate selectivity towards ONOO− over other ROS. Moreover, it is water-soluble and possesses good biocompatibility which aids the imaging of ONOO− in living cells. These properties could make the probe a promising tool in in vitro study related to ONOO−.


Polyhedron ◽  
2014 ◽  
Vol 70 ◽  
pp. 77-84 ◽  
Author(s):  
José S. Casas ◽  
María S. García-Tasende ◽  
Agustín Sánchez ◽  
Ángeles Sánchez-González ◽  
José Sordo ◽  
...  

RSC Advances ◽  
2021 ◽  
Vol 11 (35) ◽  
pp. 21813-21823
Author(s):  
Shiyue Qi ◽  
Ji Chen ◽  
Xianwei Bai ◽  
Yahui Miao ◽  
Shuhui Yang ◽  
...  

The biosynthesis of metal nanoparticles/QDs has been universally recognized as environmentally sound and energy-saving, generating less pollution and having good biocompatibility, which is most needed in biological and medical fields.


2010 ◽  
Vol 101 (1-2) ◽  
pp. 118-129 ◽  
Author(s):  
Yue-Sheng Li ◽  
Feng-Lei Jiang ◽  
Qi Xiao ◽  
Ran Li ◽  
Kan Li ◽  
...  

Author(s):  
Minwei Zhang† ◽  
Hong Ping† ◽  
Xianyi Cao ◽  
Hongkun Li ◽  
Fengrui Guan ◽  
...  

2018 ◽  
Vol 25 (25) ◽  
pp. 2876-2893 ◽  
Author(s):  
Keheng Li ◽  
Xinna Zhao ◽  
Gang Wei ◽  
Zhiqiang Su

Fluorescent graphene quantum dots (GQDs) have attracted increasing interest in cancer bioimaging due to their stable photoluminescence (PL), high stability, low cytotoxicity, and good biocompatibility. In this review, we present the synthesis and chemical modification of GQDs firstly, and then introduce their unique physical, chemical, and biological properties like the absorption, PL, and cytotoxicity of GQDs. Finally and most importantly, the recent applications of GQDs in cancer bioimaging are demonstrated in detail, in which we focus on the biofunctionalization of GQDs for specific cancer cell imaging and real-time molecular imaging in live cells. We expect this work would provide valuable guides on the synthesis and modification of GQDs with adjustable properties for various biomedical applications in the future.


Nanomaterials ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 1274 ◽  
Author(s):  
Wang ◽  
Zhao ◽  
Gao ◽  
Xu ◽  
Wang ◽  
...  

Multifunctional nanomaterials for bioprobe and drug carrier have drawn great attention for their applications in the early monitoring the progression and treatment of cancers. In this work, we have developed new multifunctional water-soluble NaLnF4@MOF-Ln nanocomposites with dual-mode luminescence, which is based on stokes luminescent mesoporous lanthanide metal–organic frameworks (MOFs-Y:Eu3+) and anti-stokes luminescent NaYF4:Tm3+/Yb3+ nanoparticles. The fluorescence mechanism and dynamics are investigated and the applications of these nanocomposites as bioprobes and drug carriers in the cancer imaging and treatment are explored. Our results demonstrate that these nanocomposites with the excellent two-color emission show great potential in drug delivery, cancer cell imaging, and treatment, which are attributed to the unique spatial structure and good biocompatibility characteristics of NaLnF4@MOF-Ln nanocomposites.


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