scholarly journals Functionalized Carbon Nanotubes with Gold Nanoparticles to Fabricate a Sensor for Hydrogen Peroxide Determination

2012 ◽  
Vol 9 (4) ◽  
pp. 2540-2549 ◽  
Author(s):  
Halimeh Rajabzade ◽  
Parandis Daneshgar ◽  
Elham Tazikeh ◽  
Ramin Zafar Mehrabian
Keyword(s):  
Hydrogen Peroxide ◽  
Gold Nanoparticles ◽  
Ionic Liquid ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Applied Potential ◽  
Carbon Paste ◽  
Experimental Conditions ◽  
Highly Sensitive ◽  
The Matrix

A highly sensitive electrode was prepared based on gold nanoparticles/nanotubes/ionic liquid for measurement of Hydrogen peroxide. Gold nanoparticles of 20–25 nm were synthesized on a nanotube carbon paste electrode by cyclic voltammetry technique while the coverage was controlled by applied potential and time. The gold nanoparticles were modified to form a monolayer on CNT, followed by decoration with ionic liquid for determination of hydrogen peroxide. The experimental conditions, applied potential and pH, for hydrogen peroxide monitoring were optimized, and hydrogen peroxide was determined amperometrically at 0.3 V vs. SCE at pH 7.0. Electrocatalytic effects of gold deposited CNT were observed with respect to unmodified one. The sensitivity obtained was 5 times higher for modified one. The presence of Au particles in the matrix of CNTs provides an environment for the enhanced electrocatalytic activities. The sensor has a high sensitivity, quickly response to H2O2and good stability. The synergistic influence of MWNT, Au particles and IL contributes to the excellent performance for the sensor. The sensor responds to H2O2in the linear range from 0.02 µM to 0.3 mM. The detection limit was down to 0.4 µM when the signal to noise ratio is 3.

scholarly journals Highly Sensitive Amperometric Detection of Hydrogen Peroxide in Saliva Based on N-Doped Graphene Nanoribbons and MnO2 Modified Carbon Paste Electrodes

Sensors ◽  
2021 ◽  
Vol 21 (24) ◽  
pp. 8301
Author(s):  
Ema Gričar ◽  
Kurt Kalcher ◽  
Boštjan Genorio ◽  
Mitja Kolar
Keyword(s):  
Hydrogen Peroxide ◽  
Limit Of Detection ◽  
Graphene Nanoribbons ◽  
Amperometric Detection ◽  
High Sensitivity ◽  
Pharmaceutical Product ◽  
Carbon Paste ◽  
Real Sample Analysis ◽  
Starting Point ◽  
Highly Sensitive

Four different graphene-based nanomaterials (htGO, N-htGO, htGONR, and N-htGONR) were synthesized, characterized, and used as a modifier of carbon paste electrode (CPE) in order to produce a reliable, precise, and highly sensitive non-enzymatic amperometric hydrogen peroxide sensor for complex matrices. CPE, with their robustness, reliability, and ease of modification, present a convenient starting point for the development of new sensors. Modification of CPE was optimized by systematically changing the type and concentration of materials in the modifier and studying the prepared electrode surface by cyclic voltammetry. N-htGONR in combination with manganese dioxide (1:1 ratio) proved to be the most appropriate material for detection of hydrogen peroxide in pharmaceutical and saliva matrices. The developed sensor exhibited a wide linear range (1.0–300 µM) and an excellent limit of detection (0.08 µM) and reproducibility, as well as high sensitivity and stability. The sensor was successfully applied to real sample analysis, where the recovery values for a commercially obtained pharmaceutical product were between 94.3% and 98.0%. Saliva samples of a user of the pharmaceutical product were also successfully analyzed.

scholarly journals Highly Sensitive and Selective Fluorescent Detection of Gossypol Based on BSA-Stabilized Copper Nanoclusters

Molecules ◽  
2018 ◽  
Vol 24 (1) ◽  
pp. 95 ◽  
Author(s):  
Shuangjiao Xu ◽  
Kehai Zhou ◽  
Dan Fang ◽  
Lei Ma
Keyword(s):  
High Performance ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Hplc Method ◽  
Fluorescent Detection ◽  
Copper Nanoclusters ◽  
Highly Sensitive ◽  
The Us ◽  
Fluorescence Quenching Mechanism ◽  
First Time

In this paper, fluorescent copper nanoclusters (NCs) are used as a novel probe for the sensitive detection of gossypol for the first time. Based on a fluorescence quenching mechanism induced by interactions between bovine serum albumin (BSA) and gossypol, fluorescent BSA-Cu NCs were seen to exhibit a high sensitivity to gossypol in the range of 0.1–100 µM. The detection limit for gossypol is 25 nM at a signal-to-noise ratio of three, which is approximately 35 times lower than the acceptable limit (0.9 µM) defined by the US Food and Drug Administration for cottonseed products. Moreover, the proposed method for gossypol displays excellent selectivity over many common interfering species. We also demonstrate the application of the present method to the measurement of several real samples with satisfactory recoveries, and the results agree well with those obtained using the high-performance liquid chromatography (HPLC) method. The method based on Cu NCs offers the followings advantages: simplicity of design, facile preparation of nanomaterials, and low experimental cost.

A highly sensitive glucose sensor based on a gold nanoparticles/polyaniline/multi-walled carbon nanotubes composite modified glassy carbon electrode

2018 ◽  
Vol 42 (14) ◽  
pp. 11944-11953 ◽  
Author(s):  
Xinping Zeng ◽  
Yazhou Zhang ◽  
Xiling Du ◽  
Yanfei Li ◽  
Wenwei Tang
Keyword(s):  
Carbon Nanotubes ◽  
Gold Nanoparticles ◽  
Glucose Sensor ◽  
High Sensitivity ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Highly Sensitive ◽  
Multi Walled Carbon Nanotubes ◽  
Application Potential ◽  
Walled Carbon Nanotubes

The PTFE/GOx/AuNPs/PANI/MWCNTs/GCE glucose sensor possesses wide linear range, low detection limit, high sensitivity, which can measure the glucose in human serum and holds application potential.

scholarly journals Highly Sensitive Biosensors Based on Biomolecules and Functional Nanomaterials Depending on the Types of Nanomaterials: A Perspective Review

Materials ◽  
2020 ◽  
Vol 13 (2) ◽  
pp. 299 ◽  
Author(s):  
Jinho Yoon ◽  
Minkyu Shin ◽  
Taek Lee ◽  
Jeong-Woo Choi
Keyword(s):  
Nucleic Acids ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Transition Metal Dichalcogenide ◽  
The Novel ◽  
Functional Nanomaterials ◽  
Complementary Sequences ◽  
Highly Sensitive ◽  
Target Molecules

Biosensors are very important for detecting target molecules with high accuracy, selectivity, and signal-to-noise ratio. Biosensors developed using biomolecules such as enzymes or nucleic acids which were used as the probes for detecting the target molecules were studied widely due to their advantages. For example, enzymes can react with certain molecules rapidly and selectively, and nucleic acids can bind to their complementary sequences delicately in nanoscale. In addition, biomolecules can be immobilized and conjugated with other materials by surface modification through the recombination or introduction of chemical linkers. However, these biosensors have some essential limitations because of instability and low signal strength derived from the detector biomolecules. Functional nanomaterials offer a solution to overcome these limitations of biomolecules by hybridization with or replacing the biomolecules. Functional nanomaterials can give advantages for developing biosensors including the increment of electrochemical signals, retention of activity of biomolecules for a long-term period, and extension of investigating tools by using its unique plasmonic and optical properties. Up to now, various nanomaterials were synthesized and reported, from widely used gold nanoparticles to novel nanomaterials that are either carbon-based or transition-metal dichalcogenide (TMD)-based. These nanomaterials were utilized either by themselves or by hybridization with other nanomaterials to develop highly sensitive biosensors. In this review, highly sensitive biosensors developed from excellent novel nanomaterials are discussed through a selective overview of recently reported researches. We also suggest creative breakthroughs for the development of next-generation biosensors using the novel nanomaterials for detecting harmful target molecules with high sensitivity.

A Novel Near-Infrared Fluorescence Sensor for H2O2 Based on N-Acetyl-L-Cysteine-Capped Gold Nanoparticles

2017 ◽  
Vol 46 ◽  
pp. 234-240
Author(s):  
Wen Juan Dong ◽  
Ji Yan Han ◽  
Xin Wu ◽  
Li Fan ◽  
Wen Ting Liang
Keyword(s):  
Hydrogen Peroxide ◽  
Gold Nanoparticles ◽  
Fluorescence Quenching ◽  
Near Infrared ◽  
Fluorescence Probe ◽  
Fluorescence Emission ◽  
Excitation Wavelength ◽  
Experimental Conditions ◽  
Time Resolved ◽  
Near Infrared Fluorescence

A novel near-infrared fluorescence quenching method has been developed for the determination of hydrogen peroxide based on N-acetyl-L-cysteine-capped gold nanoparticles (NAC-AuNPs) as a fluorescence probe. The prepared gold nanoparticles with the size of about 1.91 nm exhibited strong near-infrared fluorescence emission at 693 nm with excitation wavelength at 450 nm in aqueous solution. The fluorescence intensity of NAC-AuNPs was quenched dramatically by adding hydrogen peroxide. Therefore, it could be used to detect hydrogen peroxide based on the fluorescence quenching intensity was linear with the concentration of hydrogen peroxide. Under the optimal experimental conditions, the linear range and detection limit were 1.0×10-6 –3.0×10-2 mol/L and 1.0×10-7 mol/L, respectively. The possible quenching mechanism was investigated by time-resolved fluorescence spectroscopy. The proposed method was simple, sensitive and showed good repeatability and stability.

Highly sensitive voltammetric determination of NADH based on N-CQDs decorated SnO2/ionic liquid/carbon paste electrode

2021 ◽  
Author(s):  
Sareh Sadat Moshirian-Farahi ◽  
Hassan Ali Zamani ◽  
Mohammad Reza Abedi
Keyword(s):  
Electron Microscopy ◽  
Ionic Liquid ◽  
Folic Acid ◽  
Modified Electrode ◽  
Carbon Paste Electrode ◽  
Operating Conditions ◽  
Acid Oxidation ◽  
Carbon Paste ◽  
Highly Sensitive ◽  
Paste Electrode

Abstract A highly sensitive and selective modified electrode was successfully developed for the monitoring of nicotinamide adenine dinucleotide (NADH) in the presence of folic acid. In this regard, a carbon paste electrode (CPE) was functionalized by the nitrogen-doped carbon quantum dots/tin oxide (N-CQDs/SnO2) nanocomposite and 1-butyl-2,3-dimethyl imidazolium hexafluorophosphate ([C4DMIM][PF6]) ionic liquid (IL). The structure and surface morphology of the nanocomposite were characterized by various methods, including field emission scanning electron microscopy (FESEM), energy dispersive spectroscopy (EDS), high-resolution transmission electron microscopy (HR-TEM), and X-ray diffraction (XRD). The modified electrode displayed powerful and long-lasting electron mediating activity, with well-separated NADH and folic acid oxidation peaks. The sensing response of the developed [C4DMIM][PF6]/N-CQDs/SnO2/CPE platform was evaluated by determining NADH via the voltammetric technique under the optimized operating conditions. The current peaks of the square wave voltammograms of NADH and folic acid increased linearly with enhancing its concentrations within the ranges of 0.003 - 275 µM NADH and 0.4 - 380 µM folic acid. The detection limits for NADH and folic acid were obtained at 0.8 nM and 0.1 µM, respectively. Interference species such as glucose, urea, tryptophan, glycine, methionine, and vitamin B12 had no influence on the ability of the fabricated modified electrode to detect the target species. The low detection limit, high sensitivity, excellent selectivity, superior stability, and cost-effectiveness made it suitable for the quantification of NADH in the real biological samples with the recovery percent values in the range of 97.5 - 103%.

AgAuPt nanocages for highly sensitive detection of hydrogen peroxide

RSC Advances ◽  
2015 ◽  
Vol 5 (11) ◽  
pp. 7854-7859 ◽  
Author(s):  
Yang Peng ◽  
Ziren Yan ◽  
Ying Wu ◽  
Junwei Di
Keyword(s):  
Hydrogen Peroxide ◽  
Modified Electrode ◽  
High Sensitivity ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

AgAuPt hybrid nanocages modified electrode showed high sensitivity for the detection of hydrogen peroxide.

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