scholarly journals Prematurity and Related Biochemical Outcomes: Study of Bone Mineralization and Renal Function Parameters in Preterm Infants

2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Sarika Singh Chauhan ◽  
Purnima Dey Sarkar ◽  
Bhawna Bhimte

Preterm is defined as a baby with a gestation of less than 37 completed weeks. In this study, serum calcium, phosphorus, ALP, creatinine, and electrolytes were measured in preterm babies. The present study comprised of 75 preterm babies of which 25 were of 28–30 weeks, 25 were of 30–32 weeks, and remaining 25 were of 34–36 weeks (controls) of gestational age. Serum calcium and phosphorus levels were found to be significantly decreased, and serum ALP, creatinine, and electrolytes were found to be significantly increased () at 28–30 weeks as compared to controls, but serum calcium and phosphorous levels were found to be insignificantly decreased, whereas serum ALP activities were found to be insignificantly increased at 28–30 weeks as compared to 30–32 weeks of gestational age in preterm babies. It can be concluded that high serum ALP activity and low serum calcium and phosphorus levels are associated with preterm babies. A significant difference in the mean values of these renal function parameters was also obtained, except for serum sodium and potassium.

Author(s):  
Siti Aminah ◽  
Suparmo Suparmo ◽  
Sri Naruki ◽  
Hastari Wuryastuty

<p>Background<br />The decline in estrogens could lead to an imbalance of bone formation and absorption as well as bone mineralization. Phytoestrogens are known to have the potential to maintain bone health. Calcium and phosphorus are essential components for bone mineralization. This study aimed to investigate the effect of soybean sprout flour consumption on serum calcium and phosphorus levels in ovariectomized rats.</p><p>Methods<br />A randomized post-test-only control group design involving 25 female Sprague-Dawley rats aged 2 months, which were divided into five groups: (i) normal controls on standard feed diet AIN-93 (C-N), (ii) ovariectomy controls on standard feed diet (OVX -N); (iii) ovariectomized rats on standard feed diet + ethinylestradiol (OVX -E), (iv) ovariectomized rats on standard feed diet + soybean flour (OVX -S); (v) ovariectomized rats on standard feed diet + soybean sprout flour (OVX -SS). The rats were treated for 6 weeks, then on the last day of treatment blood sampling was conducted. Analysis of calcium and phosphorus in serum was performed using the Arsenazo III photometric method. Data were analyzed using one-way Anova.</p><p>Results<br />Mean serum calcium level was highest in the OVX-SS group (12.59 mg/dL ± 1.32), while mean serum phosphorus level was highest in the C-N group (1.708 mg/dL ± 0.28). Soybean sprout flour consumption had a significant effect on serum calcium levels (p=0.019), yet it had no effect on body weight and serum phosphorus levels of the rats.</p><p>Conclusion<br />Consumption of soybean sprout flour could positively affect serum calcium levels in rats.</p>


2017 ◽  
Vol 39 (3) ◽  
pp. 135-140
Author(s):  
Nadira Afroz ◽  
Mak Azad Chowdhury ◽  
Md Mahbubul Hoque ◽  
Dilder Ahmed Khan

Background: Despite advances in antenatal and prenatal care, incidence of preterm labor is still high. Osteopenia of prematurity is one of the common accompaniments or complications of surviving preterm babies. Most of the time this problem remains hidden, so is untreated by most of the physicians which leads to growth retardation, delayed bone maturation, fractures with minimal trauma and other complications in infancy.Objective: This study was an attempt to see osteopenia in preterm babies admitted in hospital and to see the effect of supplementation with calcium and phosphorus on those babies and to corelate serum calcium and phosphorus level with gestational age and bone density.Methods: A total 96 of preterm babies admitted in Dhaka Shishu (Children) Hospital (DSH) and Maternal & Child health Training Institute (MCHTI) of either sex were selected randomly during the period of January 2005 to June 2006. Venous blood was tested for serum calcium and phosphorus level and X-ray of lower limb to see bone density. All cases were given calcium 200 mg/kg/day and phosphorus 90 mg/kg/day with multivitamin drop of 6 drops/day up to 3 months of age.Result: Out of 96 preterm babies 27 had osteopenia with male preponderance [67%]. Gestational ages were between 28-32 weeks and in 78% cases weight were with 1000-1500 gm. Most of the mothers were 18-25 years and housewives. Initial mean serum calcium level was 1.66 mmol/l and phosphorus level was 1.58 mmol/l. After 3 months of supplementation, it was 2 mmol/l and 2.08 mmol/l respectively. Serum alkaline phosphatase was initially 736.6 and follow up level after 3 months was 353.14. Weight also increased, it was[mean] 3448 g whereas initial weight was 1277 gm.There was significant reduction of alkaline phosphatase during the 3 months [P < 0.05].Conclusion: Prevalence of osteopenia is high (28%) in premature infants. Less the gestational age more the chance of osteopenia. Calcium and Phosphorous supplementation has showed very good effect to achieve normal growth pattern.Bangladesh J Child Health 2015; VOL 39 (3) :135-140


2020 ◽  
Vol 24 (2) ◽  
pp. 202-211 ◽  
Author(s):  
Daisuke Sueta ◽  
Noriaki Tabata ◽  
Motoko Tanaka ◽  
Shinsuke Hanatani ◽  
Yuichiro Arima ◽  
...  

2003 ◽  
Vol 14 (2) ◽  
pp. 149-151
Author(s):  
P. Aruna Prabhavathi ◽  
V. Ramachandra Rao ◽  
Ch. V. Ramana Devi ◽  
P. Padmavathi ◽  
P.P. Reddy

1978 ◽  
Vol 108 (12) ◽  
pp. 1899-1906 ◽  
Author(s):  
Alfred Boris ◽  
James F. Hurley ◽  
Thelma Trmal ◽  
John P. Mallon ◽  
Diana S. Matuszewski

2014 ◽  
Vol 33 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Gheun-Ho Kim ◽  
Bum Soon Choi ◽  
Dae Ryong Cha ◽  
Dong Hyun Chee ◽  
Eunah Hwang ◽  
...  

1983 ◽  
Vol 63 (3) ◽  
pp. 699-705 ◽  
Author(s):  
J. O. ATTEH ◽  
S. LEESON

The influence of supplementing pig diets with 0, 5 or 10% fat, increasing dietary calcium and available phosphorus levels from 0.8 to 1.2% and from 0.53 to 0.8%, respectively, was investigated with 3-wk-old weaner pigs for a period of 6 wk. Average daily gain (P < 0.05) and feed intake (P < 0.01) were reduced with dietary fat supplementation. However, 10% supplemental fat in the diet caused an improvement (P < 0.05) in feed:gain ratio. Dietary calcium and phosphorus levels had no significant effect on daily weight gain, feed intake or feed:gain ratio. There was no significant effect of dietary fat or calcium and phosphorus treatment on digestibility of calcium, phosphorus or magnesium. There was also no significant difference in the pH of stomach and duodenal contents due to the dietary treatments. The rectal contents of pigs fed supplemental fat was found to be more acidic than those from the control group (P < 0.05). There was no significant effect of dietary fat, calcium and phosphorus treatments on bone or serum calcium, phosphorus or magnesium content. It is concluded that weaner pigs will tolerate high levels of fat without any detrimental effect on mineral digestibility and subsequent bone mineralization. Key words: Weaner pigs, fat, calcium, performance, bone and serum minerals


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