scholarly journals Metastatic Malignant Melanoma Presenting as an Appendiceal Mucocele

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
A. A. Alduaij ◽  
M. B. Resnick ◽  
M. Kawata ◽  
V. E. Pricolo
Keyword(s):  
Malignant Melanoma ◽  
Metastatic Melanoma ◽  
Metastatic Malignant Melanoma ◽  
Cutaneous Malignant Melanoma ◽  
Generic Diagnosis ◽  
Appendiceal Mucocele ◽  
History Of

Melanoma metastatic to the appendix is extremely rare. Here we describe a case of a 31-year-old female from Bolivia with a remote history of metastatic malignant melanoma first diagnosed as a cutaneous malignant melanoma ten years prior to this presentation. The patient was being followed for a mucocele which on resection was found to be metastatic melanoma. “Mucocele” is a generic diagnosis that warrants further characterization and treatment.

Metastatic malignant melanoma of the larynx

2001 ◽  
Vol 115 (11) ◽  
pp. 925-927 ◽  
Author(s):  
H. Pau ◽  
S. De ◽  
M. G. Spencer ◽  
P. R. M. Steele
Keyword(s):  
Malignant Melanoma ◽  
Metastatic Melanoma ◽  
Surgical Excision ◽  
Metastatic Malignant Melanoma ◽  
Cutaneous Malignant Melanoma ◽  
Diagnosis And Treatment ◽  
Metastatic Tumour ◽  
Previously Treated

Metastatic malignant melanoma of the larynx is considered to be extremely rare by most authors. This paper describes a 78-year-old patient, previously treated for cutaneous malignant melanoma and intestinal fibrosarcoma, who presented with stridor due to a metastatic melanoma in the larynx. It was a pedunculated lesion and surgical excision of the lesion was accomplished with a tonsillar snare. This paper further discusses the evolving history, diagnosis and treatment of this metastatic tumour, and reviews the literature regarding previously reported cases.

scholarly journals Case of Metastatic Malignant Melanoma Simulating Granuloma Annulare

2021 ◽  
Vol 5 (3) ◽  
pp. 289-292
Author(s):  
Haley Danielle Heibel ◽  
Parneet Dhaliwal ◽  
Etan Marks ◽  
Clay J. Cockerell
Keyword(s):  
Malignant Melanoma ◽  
Metastatic Melanoma ◽  
Immunohistochemical Staining ◽  
Previous History ◽  
Metastatic Malignant Melanoma ◽  
Granuloma Annulare ◽  
Diagnostic Challenge ◽  
Clinical Presentations ◽  
History Of ◽  
High Index Of Suspicion

Malignant melanoma and particularly metastatic melanoma represent a diagnostic challenge due to the wide variety of histologic patterns, resemblance to benign entities, and extensive range of clinical presentations.  A high index of suspicion for melanoma is important for accurate diagnosis, especially when there is a previous history of malignancy.  Here, we present a patient with a history of melanoma and locally metastatic melanoma, who subsequently developed a nodule on his right forearm near the site of his previous melanoma excision.  Histologically, the melanoma appeared as granuloma annulare (GA) with benign cytologic features, but was identified as metastatic melanoma using SOX-10 immunohistochemical staining.  Other malignancies, including lymphomas, leukemias, sarcomas, and cutaneous metastases of internal malignancies, have mimicked GA and interstitial granulomatous processes.  Therefore, further immunohistochemical staining should be performed to assess for metastatic disease in the setting of a histological pattern that resembles a benign granulomatous process in a patient with a history of malignancy, including malignant melanoma.

scholarly journals Diffuse Melanosis and Ascites due to Metastatic Malignant Melanoma

2008 ◽  
Vol 8 ◽  
pp. 556-557 ◽  
Author(s):  
Elena Sendagorta ◽  
Angel Pizarro ◽  
Marta Feito ◽  
Matias Mayor ◽  
Paloma Ramírez ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Metastatic Melanoma ◽  
Female Patient ◽  
Metastatic Malignant Melanoma ◽  
Current Evidence ◽  
Rare Entity ◽  
Skin Hyperpigmentation

We present a female patient who developed mucosal and skin hyperpigmentation due to metastatic malignant melanoma. Diffuse cutaneus melanosis is a rare entity that complicates a small percentage of metastatic melanomas, confering a fatal prognosis. We discuss briefly the current evidence on pathogenesis of melanosis arising from metastatic melanoma.

Ruptured ovarian metastatic malignant melanoma caused acute abdomen

Open Medicine ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. 241-244 ◽  
Author(s):  
Dubravko Habek ◽  
Ingrid Marton ◽  
Renato Bauman ◽  
Matija Prka ◽  
Mirna Bobić
Keyword(s):  
Malignant Melanoma ◽  
Acute Abdomen ◽  
Adnexal Mass ◽  
Protein S ◽  
Posterior Wall ◽  
Metastatic Malignant Melanoma ◽  
Cutaneous Malignant Melanoma ◽  
Primary Cutaneous Malignant Melanoma ◽  
S 100 ◽  
The Right

AbstractOvarian metastatic malignant melanoma is a rare form of disseminated malignant melanoma. We present a rare case of acute abdomen due to rupture of ovarian metastatic malignant melanoma seven years after removal of a primary cutaneous malignant melanoma lesion, followed by reexcision of the cicatrix and axillary dissection (Clark III, Breslow IV), one year after osteoplastic parietal craniotomy for removal of recidiv metastatic lesions, and excision of the cutaneous malignant melanoma lesion on the upper leg were performed. During laparotomy because of acute abdomen, 4 L of free liquid (blood and ascites) were evacuated. The right adnexal mass was loose tumor, size 110x75 mm, with rupture on the posterior wall and hemorrhage. Unilateral adnexectomy was performed. Pathohystologic evaluation revealed tumor cells with eosinophilic, clear cytoplasm, intracytoplasmatic melanotic pigment and a great number of mitosis.Immunohistochemical results supported positivity for protein S-100, whereas results for cytoceratin 7, cytoceratin 20, pancytoceratin, epithelial membrane antigen and HMB-45 were negative. Three months after the surgery the patient died due to disseminated cerebral melanoma. An adnexal mass and the history of previous MM should be suspected to be ovarian metastatic malignant melanoma and the patient should be seen by gynecologist at least for active treatment.

scholarly journals Metastatic melanoma of the stomach and the duodenum

2006 ◽  
Vol 14 (1-2) ◽  
pp. 60-61 ◽  
Author(s):  
Daniela Benedeto-Stojanov ◽  
Aleksandar Nagorni ◽  
Vesna Zivkovic ◽  
Jovica Milanovic ◽  
Dragan Stojanov
Keyword(s):  
Malignant Melanoma ◽  
Metastatic Melanoma ◽  
Duodenal Bulb ◽  
Gastrointestinal Symptoms ◽  
Endoscopic Biopsy ◽  
Upper Gastrointestinal Endoscopy ◽  
Primary Malignancy ◽  
Melanoma Metastases ◽  
History Of ◽  
One Year

A case of metastatic melanoma of the antrum and duodenal bulb is reported with rare endoscopic findings. A 59-year-old male patient was presented with nausea, vomiting, and abdominal pain one year after excision of malignant melanoma from the back. The tumor was classified as Clark IV, Breslow III. Upper gastrointestinal endoscopy revealed one melanotic polypoid mass with ulcerations at the tip in the antrum and two in the duodenal bulb. Endoscopic biopsy of these polypoid masses showed malignant melanoma metastases. Patients with gastrointestinal symptoms and a history of melanoma should be investigated for the presence of gastrointestinal metastases even if the original primary malignancy was diagnosed years prior to the patient presentation.

Recurrent primary vulvovaginal malignant melanoma arising in melanoma in situ – the natural history of lesions followed for 23 years

2004 ◽  
Vol 14 (4) ◽  
pp. 628-632
Author(s):  
N. J. Kingston ◽  
R. W. Jones ◽  
J. Baranyai
Keyword(s):  
Malignant Melanoma ◽  
Natural History ◽  
Metastatic Melanoma ◽  
Cutaneous Melanoma ◽  
Mucosal Melanoma ◽  
Histologic Examination ◽  
Melanoma In Situ ◽  
Pigmented Lesions ◽  
History Of

Multifocal melanoma and melanoma in situ of the vulva and vagina are uncommon lesions, and our understanding of their natural history is limited. Vulvovaginal melanoma appears to be biologically different from cutaneous melanoma and has more in common with mucosal melanoma. A 60-year-old woman presented in 1977 with a pigmented vulvar lesion. Histologic examination revealed melanoma in situ associated with focal invasive melanoma. She re-presented with recurrent primary melanomas arising in melanoma in situ in 1990 and 1998 and died of widespread metastatic melanoma in 2000. Melanoma in situ of the vulva and vagina is rare and appears to have a relatively slow but definite progression to invasive melanoma. All suspicious pigmented lesions in this region should be biopsied, and if multifocal in situ melanoma is identified, vulvo(vagin)ectomy should be considered.

scholarly journals Nivolumab Induced Lethal Aplastic Anemia in a Patient with Metastatic Melanoma

2019 ◽  
Vol 12 (1) ◽  
pp. 29-32 ◽  
Author(s):  
Keren Rouvinov ◽  
Karen Nalbandyan ◽  
Victor Kozlov ◽  
Nir Peled ◽  
Alexander Yakobson
Keyword(s):  
Malignant Melanoma ◽  
Aplastic Anemia ◽  
Metastatic Melanoma ◽  
Active Treatment ◽  
Melanoma Patient ◽  
Case Reports ◽  
Metastatic Malignant Melanoma ◽  
Line Treatment ◽  
Metastatic Melanoma Patient ◽  
Advanced Line

Nivolumab is an active treatment in patients with metastatic melanoma. We report a case of a patient with metastatic malignant melanoma who was given nivolumab as an advanced-line treatment. She received nivolumab 3 mg/kg every 2 weeks for 4 cycles and developed aplastic anemia. To the best of our knowledge, there are only three published case reports that have shown aplastic anemia in patients who have been treated by immunotherapy. This is the first report of a lethal aplastic anemia during nivolumab monotherapy in a metastatic melanoma patient.

scholarly journals The Influence of Pregnancy on the Recurrence of Cutaneous Malignant Melanoma in Women

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
M. Albersen ◽  
V. I. Westerling ◽  
P. A. M. van Leeuwen
Keyword(s):  
Malignant Melanoma ◽  
Disease Free Survival ◽  
Recurrence Risk ◽  
Cutaneous Malignant Melanoma ◽  
Stage I ◽  
Free Survival ◽  
Medical Databases ◽  
Significant Difference ◽  
History Of ◽  
Disease Free

Objective. The aim of this study was to determine whether pregnancy increases the recurrence risk of cutaneous malignant melanoma (CMM) in women with a history of stage I CMM.Methods. The electronic medical databases of Medline and Embase were explored. All 1084 obtained articles were screened on title and abstract using predetermined inclusion and exclusion criteria. A critical appraisal of relevance and validity was conducted on the remaining full text available articles.Results. Two studies were selected. Both studies revealed no significant difference in disease-free survival between women with stage I CMM and the control population.Conclusion. Pregnancy does not increase the recurrence risk of CMM in women with a history of stage I CMM.

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