scholarly journals Autonoetic Consciousness in Autobiographical Memories after Medial Temporal Lobe Resection

2008 ◽  
Vol 19 (1-2) ◽  
pp. 19-22 ◽  
Author(s):  
M. Noulhiane ◽  
P. Piolino ◽  
D. Hasboun ◽  
S. Clemenceau ◽  
M. Baulac ◽  
...  
Keyword(s):  
Autobiographical Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Memory Task ◽  
Intractable Epilepsy ◽  
Temporal Lobe Resection ◽  
Patient Groups ◽  
Left And Right ◽  
Autonoetic Consciousness ◽  
Multiple Trace Theory

This study aims to investigate autonoetic consciousness associated with episodic autobiographical memory in patients who had undergone unilateral medial temporal lobe resection for intractable epilepsy. Autonoetic consciousness, defined as the conscious feeling of mentally travelling back in time to relive a specific event, was assessed using the Remember/Know (R/K) paradigm across different time periods as proposed in the autobiographical memory task developed by Piolino et al. (TEMPau task). Results revealed that the two patient groups (left and right temporal resection) gave reduced sense of reliving (R) responses and more familiarity (K) responses than healthy controls. This poor autonoetic consciousness was highlighted when patients were asked to justify their Remember responses by recalling sensory-perceptive, affective or spatiotemporal specific details across all life periods. These results support the bilateral MTL contribution to episodic autobiographical memory covering the entire lifespan, which is consistent with the multiple trace theory of MTL function [7,9]. This study also demonstrates the bilateral involvement of MTL structures in recalling specific details of personal events characterized by autonoetic consciousness.

scholarly journals Autobiographical Memory Retrieval and Hippocampal Activation as a Function of Repetition and the Passage of Time

2007 ◽  
Vol 2007 ◽  
pp. 1-14 ◽  
Author(s):  
Lynn Nadel ◽  
Jenna Campbell ◽  
Lee Ryan
Keyword(s):  
Autobiographical Memory ◽  
Temporal Lobe ◽  
Memory Retrieval ◽  
Medial Temporal Lobe ◽  
Perirhinal Cortex ◽  
Brain Regions ◽  
Long Term Memory ◽  
Memory Traces ◽  
Multiple Trace Theory

Multiple trace theory (MTT) predicts that hippocampal memory traces expand and strengthen as a function of repeated memory retrievals. We tested this hypothesis utilizing fMRI, comparing the effect of memory retrieval versus the mere passage of time on hippocampal activation. While undergoing fMRI scanning, participants retrieved remote autobiographical memories that had been previously retrieved either one month earlier, two days earlier, or multiple times during the preceding month. Behavioral analyses revealed that the number and consistency of memory details retrieved increased with multiple retrievals but not with the passage of time. While all three retrieval conditions activated a similar set of brain regions normally associated with autobiographical memory retrieval including medial temporal lobe structures, hippocampal activation did not change as a function of either multiple retrievals or the passage of time. However, activation in other brain regions, including the precuneus, lateral prefrontal cortex, parietal cortex, lateral temporal lobe, and perirhinal cortex increased after multiple retrievals, but was not influenced by the passage of time. These results have important implications for existing theories of long-term memory consolidation.

scholarly journals Autobiographical memory, future imagining, and the medial temporal lobe

2016 ◽  
Vol 113 (47) ◽  
pp. 13474-13479 ◽  
Author(s):  
Adam J. O. Dede ◽  
John T. Wixted ◽  
Ramona O. Hopkins ◽  
Larry R. Squire
Keyword(s):  
Autobiographical Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Memory Impairment ◽  
Anterograde Amnesia ◽  
Independent Analysis ◽  
The Status ◽  
Future Events ◽  
Patient Groups ◽  
Remote Past

In two experiments, patients with damage to the medial temporal lobe (MTL) and healthy controls produced detailed autobiographical narratives as they remembered past events (recent and remote) and imagined future events (near and distant). All recent events occurred after the onset of memory impairment. The first experiment aimed to replicate the methods of Race et al. [Race E, Keane MM, Verfaellie M (2011) J Neurosci 31(28):10262–10269]. Transcripts from that study were kindly made available for independent analysis, which largely reproduced the findings from that study. Our patients produced marginally fewer episodic details than controls. Patients from the earlier study were more impaired than our patients. Patients in both groups had difficulty in returning to their narratives after going on tangents, suggesting that anterograde memory impairment may have interfered with narrative construction. In experiment 2, the experimenter used supportive questioning to help keep participants on task and reduce the burden on anterograde memory. This procedure increased the number of details produced by all participants and rescued the performance of our patients for the distant past. Neither of the two patient groups had any special difficulty in producing spatial details. The findings suggest that constructing narratives about the remote past and the future does not depend on MTL structures, except to the extent that anterograde amnesia affects performance. The results further suggest that different findings about the status of autobiographical memory likely depend on differences in the location and extent of brain damage in different patient groups.

scholarly journals Intractable Temporal Lobe Epilepsy (TLE) From Tuberculoma; Microneurosurgical Management of by Amygdalohippocampectomy with Lesionectomy Plus Standard Anterior Temporal lobectomy: A Case Report and Short Review of Literature

2019 ◽  
Vol 16 (2) ◽  
pp. 106-109
Author(s):  
Forhad Hossain Chowdhury ◽  
Mohammod Raziul Haque ◽  
AFM Momtazul Haque
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Venous Malformation ◽  
Intractable Epilepsy ◽  
Complex Partial Seizure ◽  
Temporal Lobectomy ◽  
Mesial Temporal Sclerosis ◽  
Low Grade ◽  
Presenting Symptoms

Patient presenting as a case of Temporal Lobe Epilepsy (TLE) are usually resistant to antiepileptic drugs and surgery is the treatment of choice. This type of epilepsy may be due to Mesial Temporal Sclerosis (MTS), tumors [i.e. low grade glioma, Arterio-venous Malformation (AVM) etc], trauma, infection (Tuberculosis) etc. Here we report a case of surgically treated TLE that was due to a large tuberculoma in medial temporal lobe. Intractable epilepsy caused by tuberculoma is rare. The only presenting symptoms was Complex partial seizure (Psychomotor epilepsy) for which the patient underwent scalp EEG (Electro Encephalography) and MRI (Magnetic resonance imaging) of brain. The patient was managed by amygdalohippocampectomy with lesionectomy plus standard anterior lobectomy. Postoperatively she was on anti-tubercular therapy and on carbamazepine. The case was seizure and disease free till last follow up. Journal of Surgical Sciences (2012) Vol. 16 (2) : 106-109

scholarly journals Autobiographical Memory and Patterns of Brain Atrophy in Fronto-temporal Lobar Degeneration

2008 ◽  
Vol 20 (10) ◽  
pp. 1839-1853 ◽  
Author(s):  
Margaret C. McKinnon ◽  
Elena I. Nica ◽  
Pheth Sengdy ◽  
Natasa Kovacevic ◽  
Morris Moscovitch ◽  
...  
Keyword(s):  
Autobiographical Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Functional Neuroimaging ◽  
Memory Loss ◽  
Behavioral Pattern ◽  
Remote Memory ◽  
Semantic Retrieval ◽  
Cross Sectional ◽  
Matched Comparison

Autobiographical memory paradigms have been increasingly used to study the behavioral and neuroanatomical correlates of human remote memory. Although there are numerous functional neuroimaging studies on this topic, relatively few studies of patient samples exist, with heterogeneity of results owing to methodological variability. In this study, fronto-temporal lobar degeneration (FTLD), a form of dementia affecting regions crucial to autobiographical memory, was used as a model of autobiographical memory loss. We emphasized the separation of episodic (recollection of specific event, perceptual, and mental state information) from semantic (factual information unspecific in time and place) autobiographical memory, derived from a reliable method for scoring transcribed autobiographical protocols, the Autobiographical Interview [Levine, B., Svoboda, E., Hay, J., Winocur, G., & Moscovitch, M. Aging and autobiographical memory: Dissociating episodic from semantic retrieval. Psychology and Aging, 17, 677–689, 2002]. Patients with the fronto-temporal dementia (FTD) and mixed fronto-temporal and semantic dementia (FTD/SD) variants of FTLD were impaired at reconstructing episodically rich autobiographical memories across the lifespan, with FTD/SD patients generating an excess of generic semantic autobiographical information. Patients with progressive nonfluent aphasia were mildly impaired for episodic autobiographical memory, but this impairment was eliminated with the provision of structured cueing, likely reflecting relatively intact medial-temporal lobe function, whereas the same cueing failed to bolster the FTD and FTD/SD patients' performance relative to that of matched comparison subjects. The pattern of episodic, but not semantic, autobiographical impairment was enhanced with disease progression on 1- to 2-year follow-up testing in a subset of patients, supplementing the cross-sectional evidence for specificity of episodic autobiographical impairment with longitudinal data. This behavioral pattern covaried with volume loss in a distributed left-lateralized posterior network centered on the temporal lobe, consistent with evidence from other patient and functional neuroimaging studies of autobiographical memory. Frontal lobe volumes, however, did not significantly contribute to this network, suggesting that frontal contributions to autobiographical episodic memory may be more complex than previously appreciated.

Visuo-spatial memory deficits following medial temporal lobe damage: A comparison of three patient groups

2016 ◽  
Vol 81 ◽  
pp. 168-179 ◽  
Author(s):  
Nazli Esfahani-Bayerl ◽  
Carsten Finke ◽  
Mischa Braun ◽  
Emrah Düzel ◽  
Hauke R. Heekeren ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Memory Deficits ◽  
Patient Groups

Phase/amplitude reset and theta-gamma interaction in the human medial temporal lobe during a continuous word recognition memory task

Hippocampus ◽  
2005 ◽  
Vol 15 (7) ◽  
pp. 890-900 ◽  
Author(s):  
Florian Mormann ◽  
Juergen Fell ◽  
Nikolai Axmacher ◽  
Bernd Weber ◽  
Klaus Lehnertz ◽  
...  
Keyword(s):  
Word Recognition ◽  
Recognition Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Memory Task ◽  
Recognition Memory Task ◽  
Phase Amplitude

scholarly journals Decision-making impairments following insular and medial temporal lobe resection for drug-resistant epilepsy

2016 ◽  
pp. nsw152 ◽  
Author(s):  
Zorina Von Siebenthal ◽  
Olivier Boucher ◽  
Isabelle Rouleau ◽  
Maryse Lassonde ◽  
Franco Lepore ◽  
...  
Keyword(s):  
Decision Making ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Drug Resistant ◽  
Temporal Lobe Resection ◽  
Drug Resistant Epilepsy
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