scholarly journals Decision-making impairments following insular and medial temporal lobe resection for drug-resistant epilepsy

2016 ◽  
pp. nsw152 ◽  
Author(s):  
Zorina Von Siebenthal ◽  
Olivier Boucher ◽  
Isabelle Rouleau ◽  
Maryse Lassonde ◽  
Franco Lepore ◽  
...  
Keyword(s):  
Decision Making ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Drug Resistant ◽  
Temporal Lobe Resection ◽  
Drug Resistant Epilepsy

Stereoelectroencephalographic language mapping of the basal temporal cortex predicts postoperative naming outcome

2021 ◽  
pp. 1-11
Author(s):  
Chifaou Abdallah ◽  
Hélène Brissart ◽  
Sophie Colnat-Coulbois ◽  
Ludovic Pierson ◽  
Olivier Aron ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Verbal Fluency ◽  
Temporal Cortex ◽  
Visual Object ◽  
Drug Resistant ◽  
Language Mapping ◽  
Individual Level ◽  
Language Outcome ◽  
Temporal Lobe Resection ◽  
The Individual

OBJECTIVEIn drug-resistant temporal lobe epilepsy (TLE) patients, the authors evaluated early and late outcomes for decline in visual object naming after dominant temporal lobe resection (TLR) according to the resection status of the basal temporal language area (BTLA) identified by cortical stimulation during stereoelectroencephalography (SEEG).METHODSTwenty patients who underwent SEEG for drug-resistant TLE met the inclusion criteria. During language mapping, a site was considered positive when stimulation of two contiguous contacts elicited at least one naming impairment during two remote sessions. After TLR ipsilateral to their BTLA, patients were classified as BTLA+ when at least one positive language site was resected and as BTLA− when all positive language sites were preserved. Outcomes in naming and verbal fluency tests were assessed using pre- and postoperative (means of 7 and 25 months after surgery) scores at the group level and reliable change indices (RCIs) for clinically meaningful changes at the individual level.RESULTSBTLA+ patients (n = 7) had significantly worse naming scores than BTLA− patients (n = 13) within 1 year after surgery but not at the long-term evaluation. No difference in verbal fluency tests was observed. When RCIs were used, 5 of 18 patients (28%) had naming decline within 1 year postoperatively (corresponding to 57% of BTLA+ and 9% of BTLA− patients). A significant correlation was found between BTLA resection and naming decline.CONCLUSIONSBTLA resection is associated with a specific and early naming decline. Even if this decline is transient, naming scores in BTLA+ patients tend to remain lower compared to their baseline. SEEG mapping helps to predict postoperative language outcome after dominant TLR.

scholarly journals Nuclei-specific thalamic connectivity predicts seizure frequency in drug-resistant medial temporal lobe epilepsy

2019 ◽  
Vol 21 ◽  
pp. 101671 ◽  
Author(s):  
Hang Joon Jo ◽  
Daniel L. Kenny-Jung ◽  
Irena Balzekas ◽  
Eduardo E. Benarroch ◽  
David T. Jones ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Seizure Frequency ◽  
Medial Temporal Lobe ◽  
Drug Resistant ◽  
Medial Temporal Lobe Epilepsy

scholarly journals Novel Neurotechnological Interventions for Pediatric Drug-Resistant Epilepsy: Physician Perspectives

2020 ◽  
pp. 088307382096693
Author(s):  
Patrick J. McDonald ◽  
Viorica Hrincu ◽  
Mary B. Connolly ◽  
Mark J. Harrison ◽  
George M. Ibrahim ◽  
...  
Keyword(s):  
Decision Making ◽  
Best Practice ◽  
Clinical Decision Making ◽  
Qualitative Content Analysis ◽  
Scientific Evidence ◽  
Clinical Decision ◽  
Drug Resistant ◽  
Ethical Considerations ◽  
Pediatric Drug ◽  
Drug Resistant Epilepsy

This qualitative study investigated factors that guide physicians’ choices for minimally invasive and neuromodulatory interventions as alternatives to conventional surgery or medical management for pediatric drug-resistant epilepsy. North American physicians were recruited to one of 4 focus groups at national conferences. Discussions were analyzed using qualitative content analysis. A pragmatic neuroethics framework was applied to interpret results. Discussions revealed 2 major thematic branches: (1) clinical decision making and (2) ethical considerations. Under clinical decision making, physicians emphasized scientific evidence and patient candidacy when assessing neurotechnologies for patients. Ongoing seizures without intervention was important for safety and neurodevelopment. Under ethical considerations, resource allocation, among other financial considerations for technology adoption, were considerable sources of pressure on decision making. Access to neurotechnology was a salient theme differentiating Canadian and American contexts. When assessing novel neurotechnological interventions for pediatric drug-resistant epilepsy, physicians balance clinical and ethical factors to guide decision making and best practice.

Do sphenoidal electrodes aid in surgical decision making in drug resistant temporal lobe epilepsy?

2012 ◽  
Vol 123 (3) ◽  
pp. 463-470 ◽  
Author(s):  
Ajith Cherian ◽  
Ashalatha Radhakrishnan ◽  
Sajeesh Parameswaran ◽  
Raviprasad Varma ◽  
Kurupath Radhakrishnan
Keyword(s):  
Decision Making ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Drug Resistant ◽  
Surgical Decision ◽  
Surgical Decision Making

Understanding the association of neurocysticercosis and mesial temporal lobe epilepsy and its impact on the surgical treatment of patients with drug-resistant epilepsy

2017 ◽  
Vol 76 ◽  
pp. 168-177 ◽  
Author(s):  
Marino Muxfeldt Bianchin ◽  
Tonicarlo Rodrigues Velasco ◽  
Lauro Wichert-Ana ◽  
Antonio Carlos dos Santos ◽  
Américo Ceiki Sakamoto
Keyword(s):  
Surgical Treatment ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Mesial Temporal Lobe Epilepsy ◽  
Drug Resistant ◽  
Mesial Temporal Lobe ◽  
Drug Resistant Epilepsy

scholarly journals Erratum to: Markers of Neuroinflammation and Apoptosis in the Temporal Lobe of Patients with Drug-Resistant Epilepsy

2021 ◽  
Vol 57 (6) ◽  
pp. 1533-1533
Author(s):  
A. V. Litovchenko ◽  
Yu. M. Zabrodskaya ◽  
D. A. Sitovskaya ◽  
L. K. Khuzhakhmetova ◽  
V. G. Nezdorovina ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Drug Resistant ◽  
Drug Resistant Epilepsy

Psychiatric outcome of epilepsy surgery in patients with psychosis and temporal lobe drug-resistant epilepsy: A prospective case series

2014 ◽  
Vol 37 ◽  
pp. 165-170 ◽  
Author(s):  
Luciana D'Alessio ◽  
Laura Scévola ◽  
Mónica Fernandez Lima ◽  
Silvia Oddo ◽  
Patricia Solís ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Epilepsy Surgery ◽  
Case Series ◽  
Drug Resistant ◽  
Prospective Case Series ◽  
Drug Resistant Epilepsy ◽  
Psychiatric Outcome

Erratum to “Auditory/visual duration bisection in patients with left or right medial-temporal lobe resection” [Brain and Cognition 58 (2005) 119–124]

2006 ◽  
Vol 60 (1) ◽  
pp. 105
Author(s):  
Manuela Melgire ◽  
Richard Ragot ◽  
Séverine Samson ◽  
Trevor B. Penney ◽  
Warren H. Meck ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Temporal Lobe Resection
Sign in / Sign up

Export Citation Format

Share Document