scholarly journals Colonic Squamous Cell Carcinoma in Ulcerative Colitis: Report of a Case and Review of the Literature

2007 ◽  
Vol 21 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Huilan Cheng ◽  
Michael D Sitrin ◽  
Sateesh K Satchidanand ◽  
Jan M Novak

Squamous cell carcinoma (SCC) is a rare neoplasm in the colorectum. A case of SCC rising from an area of squamous metaplasia in the rectum is presented in a patient with long-standing ulcerative colitis and perianal warts. This is the first report in the literature describing the evolution of squamous metaplasia in the colonic mucosa into invasive carcinoma over time. Related literature on colorectal SCC and squamous metaplasia, and their relationships with inflammatory bowel disease and human papilloma virus, is reviewed.

2006 ◽  
Vol 22 (4) ◽  
pp. 445-447 ◽  
Author(s):  
Alon J. Pikarsky ◽  
Bruce Belin ◽  
Jonathan Efron ◽  
Sherry Woodhouse ◽  
Eric G. Weiss ◽  
...  

2017 ◽  
Vol 10 (1) ◽  
pp. 112-122 ◽  
Author(s):  
Gianluca Pellino ◽  
Christos Kontovounisios ◽  
Diana Tait ◽  
John Nicholls ◽  
Paris P. Tekkis

Background: Few cases of pouch-related cancers have been reported in ulcerative colitis (UC), and squamous cell carcinoma (SCC) is very rare. Method: A systematic review of the literature was performed to identify all unequivocal cases of pouch-related SCC in UC patients. Results: Eight cases of SCC developing after ileal pouch-anal anastomosis (IPAA) have been observed since 1978. Two arose from the pouch mucosa and 6 from below. The pooled cumulative incidence of SCC is below 0.06% after IPAA. Many patients had neoplasia on the preoperative specimen, but squamous metaplasia of the pouch or anorectal mucosa may have an important role in SCC. These patients are rarely offered chemoradiation therapy and the outcome is poor. Selected patients with SCC located close to the pouch outlet can be treated with chemoradiation prior to consideration of surgery and salvage their pouch. A chemoradiation regimen is suggested to avoid pouch excision in these patients. Conclusions: SCC is rare after pouch surgery but associated with extremely poor survival. Very low SCC can be managed with chemoradiation treatment, preserving the pouch and avoiding surgery, even in older patients. The role of pouch metaplasia, surveillance frequency, and treatment modalities after IPAA need further studying.


2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Tapan Kumar Sahoo ◽  
Saroj Kumar Das ◽  
Chandraprava Mishra ◽  
Ipsita Dhal ◽  
Rohani Nayak ◽  
...  

Primary squamous cell carcinoma of the renal parenchyma is an extremely rare entity. The diagnosis of squamous cell carcinoma of the renal pelvis is usually unsuspected due to the rarity and inconclusive clinical and radiological features. Most of the patients are diagnosed at an advanced stage and are with poor outcome. Radical nephrectomy is the mainstay of the treatment. We reported a case of squamous cell carcinoma of the kidney in a 50-year-old female who presented with the right sided abdomen pain. The patient was treated with radical nephrectomy.


2018 ◽  
Vol 109 (5) ◽  
pp. 457-459
Author(s):  
J.M. Segura Palacios ◽  
P. García Montero ◽  
R. Fúnez Liébana ◽  
J.B. Repiso Jiménez

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