scholarly journals Transition Metal Complexes of Methyl-quinolino[3,2-b][1,5]benzodiazepine and Methylquinolino [3,2-b][1,5]benzoxazepine: Synthesis, Characterisation and Antimicrobial Studies

2007 ◽  
Vol 4 (1) ◽  
pp. 39-45
Author(s):  
B. Basavaraju ◽  
H. S. Bhojya Naik ◽  
M. C. Prabhakara
Keyword(s):  
Antifungal Activity ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Molar Conductance ◽  
Antibacterial And Antifungal Activity ◽  
Magnetic Studies ◽  
H Nmr ◽  
Antimicrobial Studies ◽  
Uv Visible ◽  
Antibacterial And Antifungal

The synthesis and characterisation of title complexes of the ligand Methylquinolino[3,2-b][1,5]benzodiazepine (MQBD) and Methyl-quinolino[3,2-b][1,5]benzoxazepine (MQBO) are reported. The complexes have been characterized by elemental analysis, molar conductance, magnetic studies, IR,1H NMR and UV-visible studies. They have the stoichiometry [ML2Cl2] where M=Co(II)/Ni(II), L=MQBD/MQBO and [MLCl2] where M=Zn(II)/Cd(II), L=MQBD/MQBO. The antibacterial and antifungal activity of the metal complexes has been investigated.

scholarly journals Transition Metal Complexes of Quinolino[3,2-b]benzodiazepine and Quinolino[3,2-b]benzoxazepine: Synthesis, Characterization, and Antimicrobial Studies

2007 ◽  
Vol 2007 ◽  
pp. 1-6 ◽  
Author(s):  
B. Basavaraju ◽  
Halehatty S. Bhojya Naik ◽  
Mustur C. Prabhakara
Keyword(s):  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Molar Conductance ◽  
Antibacterial And Antifungal Activity ◽  
Magnetic Studies ◽  
Antimicrobial Studies ◽  
Uv Visible ◽  
Antibacterial And Antifungal ◽  
Parent Ligand

The synthesis and characterization of title complexes of the ligand Quinolino[3,2-b]benzodiazepine (QBD) and Quinolino[3,2-b]benzoxazepine (QBO) are reported. The complexes have been characterized by elemental analysis, molar conductance, magnetic studies, IR,HNMR, and UV-visible studies. They have the stoichiometry [ML2C12], where M=Co(II)/Ni(II), L=QBD/QBO, and [MLC12], where M=Zn(II)/Cd(II), L=QBD/QBO. The antibacterial and antifungal activity of the metal complexes has been investigated. The complexes were found to have higher antimicrobial activity than the parent ligand.

scholarly journals Transition Metal Complexes of 1, 4(2'-Hydroxyphenyl-1-yl) di-imino azine: Synthesis, Characterization and Antimicrobial Studies

2008 ◽  
Vol 5 (2) ◽  
pp. 395-403 ◽  
Author(s):  
M. Revanasiddappa ◽  
T. Suresh ◽  
Syed Khasim ◽  
S. C. Raghavendray ◽  
C. Basavaraja ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Molar Conductance ◽  
Antibacterial And Antifungal Activity ◽  
Magnetic Studies ◽  
Antimicrobial Studies ◽  
Antibacterial And Antifungal

The synthesis and characterization of first row transition metal complexes of the 1, 4(2'-hydroxyphenyl-1-yl) di-imino azine {1,4(2'HPDA)} are reported. The complexes have been characterized by elemental analysis, molar conductance, magnetic studies, IR, 1H NMR and UV-visible studies. They have the stoichiometry of the type [M{1,4(2'HPDA)}22H2O ] and [M'L2] where M= Mn(II), Fe(III), Co(II), Ni(II) and Cu(II), and M' = ZrO(II), VO(II), Zn(II), Cd(II), and Hg(II). The antibacterial and antifungal activity of the metal complexes has been investigated. Both ligand and complexes have shown good antibacterial and antifungal activity.

scholarly journals Synthesis, Characterization and Antimicrobial Studies of N1-[(1E)-1-(2-Hydroxyphenyl) ethylidene]-2-oxo-2H-chromene-3-carbohydrazide and its Metal Complexes

2009 ◽  
Vol 6 (3) ◽  
pp. 615-624 ◽  
Author(s):  
K. Siddappa ◽  
K. Mallikarjun ◽  
Tukaram Reddy ◽  
M. Mallikarjun ◽  
C. V. Reddy ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Magnetic Susceptibility ◽  
Schiff Base ◽  
Metal Complexes ◽  
Molar Conductance ◽  
Tetrahedral Geometry ◽  
H Nmr ◽  
Antimicrobial Studies ◽  
Mononuclear Complexes ◽  
Uv Visible

A new complexes of the type ML, MʹL and M″L [where M=Cu(II), Co(II), Ni(II) and Mn(II), Mʹ=Fe(III) and M″=Zn(II), Cd(II) and Hg(II) and L=N1-[(1E)-1-(2-hydroxyphenyl)ethylidene]-2-oxo-2H-chromene- 3-carbohydrazide (HL)] Schiff base have been synthesized and characterized by elemental analysis, magnetic susceptibility, molar conductance, IR,1H NMR, UV-Visible and ESR data. The studies indicate the HL acts as doubly monodentate bridge for metal ions and form mononuclear complexes. The complexes Ni(II), Co(II), Cu(II) Mn(II) and Fe(III) complexes are found to be octahedral, where as Zn(II), Cd(II) and Hg(II) complexes are four coordinated with tetrahedral geometry. The synthesized ligand and its metal complexes were screened for their antimicrobial activity.

scholarly journals Synthesis, Characterization and Antimicrobial Activity of Methylquinolino[3,2-b][1,5]benzodiazepine and Methylquinolino[3,2-b][1,5]benzoxazepine and its Various Metal Complexes

2007 ◽  
Vol 4 (1) ◽  
pp. 32-38 ◽  
Author(s):  
B. Basavaraju ◽  
H. S. Bhojya Naik ◽  
M. C. Prabhakara
Keyword(s):  
Antimicrobial Activity ◽  
Metal Complexes ◽  
Antimicrobial Agents ◽  
Spectral Studies ◽  
Antibacterial And Antifungal Activity ◽  
H Nmr ◽  
Uv Visible ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal ◽  
Metal Ligand

2-Chloro-6-methylquinoline-3-carbaldehyde was condensed witho-Phenylenediammine and 2-aminophenol in presence of potassium iodide. The resulting Methylquinolino[3,2-b][1,5]benzodiazepine (MQBD) and Methylquinolino[3,2-b][1,5]benzoxazepine(MQBO) were characterized by elemental analysis and spectral studies. The metal chelatesvizPd(II), Rh(III) and Ru(III) of ligands were prepared and characterized by metal-ligand (M:L) ratio, UV-Visible, IR,1H NMR spectroscopes and magnetic properties. The antibacterial and antifungal activity of MQBD, MQBO and its metal complexes were screened against various bacteria and fungi. The results show that all these samples are good antimicrobial agents.

Synthesis, characterization antibacterial and antifungal activity of some transition metal complexes

2013 ◽  
Vol 23 (5) ◽  
pp. 2207-2211 ◽  
Author(s):  
Wajid Rehman ◽  
Zonera Hassan ◽  
Umer Rashid ◽  
Fazal Rahim ◽  
Obaid-Ur-Rahman Abid ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Antibacterial And Antifungal Activity ◽  
Antibacterial And Antifungal

scholarly journals Studies on Antibacterial and Antifungal Activities and Minimum Inhibitory Concentrations of Mixed Ligand Transition Metal Complexes of Dibasic Acids as Primary and Heterocyclic Bases as Secondary Ligands

1970 ◽  
Vol 46 (3) ◽  
pp. 365-368 ◽  
Author(s):  
MA Akbor ◽  
MS Islam ◽  
N Akhter ◽  
S Ahmed ◽  
S Siraj
Keyword(s):  
Antifungal Activity ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Mixed Ligand ◽  
Diffusion Method ◽  
Antifungal Activities ◽  
Minimum Inhibitory Concentrations ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

Mixed ligand (diphenic/ adipic as primary Ligand and quinoline / 8 - hydroxyquinoline as secondary) transition metal complexes of Cobalt (II), Cupper (II), Rhodium (III) and Platinum (IV) ions were synthesized and characterized. Their antibacterial activities against ten bacteria had been evaluated by the disc diffusion method,whilst their antifungal activities against two fungi had been also evaluated by the same method. Minimum inhibitory concentrations (MIC) had been evaluated against six bacteria. The MIC of the complexes against Shigella dysenteriae, Samonella typhi, Streptococcus-β-haemolyticus and Bacillus megaterium were 32 μg/ml; whilst Escherichia coli and Samonella typhi-A the MIC of Co (II) and Pt (IV) were 32μg/ml and those of Cu(II) and Rh(III) complexes were 64 μg/ml. It was found that Cobalt (II), Cupper (II) & Rhodium (III) complexes had pronounced antibacterial and antifungal activities. Platinum (IV) complex had moderate antibacterial and antifungal activity. These values indicate that these are active compounds. Key words: Mixed Ligand; Transition metal; Antimicrobial Activity; Antifungal Activity Minimum Inhibitory Concentrations (MIC) DOI: http://dx.doi.org/10.3329/bjsir.v46i3.9044 BJSIR 2011; 46(3): 365-368

scholarly journals Coordination Modes of a Schiff Base Derived from Substituted 2-Aminothiazole with Chromium(III), Manganese(II), Iron(II), Cobalt(II), Nickel(II) and Copper(II) Metal Ions: Synthesis, Spectroscopic and Antimicrobial Studies

2011 ◽  
Vol 8 (4) ◽  
pp. 1750-1764 ◽  
Author(s):  
Ambit Thakar ◽  
Krishnakant Joshi ◽  
Kishor Pandya ◽  
Arvind Pancholi
Keyword(s):  
Schiff Base ◽  
Metal Ions ◽  
Transition Metal Complexes ◽  
Mass Spectra ◽  
Antibacterial Activities ◽  
Molar Conductance ◽  
Spectral Techniques ◽  
H Nmr ◽  
Antimicrobial Studies ◽  
C Nmr

Transition metal complexes of Cr(III), Mn(II), Fe(II), Co(II), Ni(II) and Cu(II) metal ions with general stoichiometry [ML2.2H2O] and [ML3], where M= Mn(II), Cr(III), Fe(II), Co(II), Ni(II) and Cu(II), L= Schiff base derived from the condensation of 2-amino-4(4’-phenyl/methylphenyl)-5-methyl-thiazole with 4-acetyl-1(3-chloro phenyl)-3-methyl-2-pyrazoline-5-ones, have been synthesized and structurally characterized by elemental analysis, molar conductance measurements, magnetic susceptibility measurements and spectral techniques like IR, UV,1H NMR,13C NMR and Mass Spectra. All the complexes were found to be octahedral geometry. The ligand and its complexes have been screened for their antifungal and antibacterial activities against three fungi,i.e. Alternaria brassicae, Aspergillus nigerandFesarium oxysporumand two bacteria,i.e. Xanthomonas compestrisandPseudomonas aeruginosa.

scholarly journals Synthesis, Characterization and Antimicrobial Studies of 3-[(2-Hydroxy-quinolin-3-ylmethylene)-amino]-2-phenyl-3H-quinazolin-4-one and its Metal(II) Complexes

2008 ◽  
Vol 5 (1) ◽  
pp. 155-162 ◽  
Author(s):  
K. Siddappa ◽  
Tukaram Reddy ◽  
M. Mallikarjun ◽  
C. V. Reddy
Keyword(s):  
Antimicrobial Activity ◽  
Magnetic Susceptibility ◽  
Schiff Base ◽  
Elemental Analysis ◽  
Molar Conductance ◽  
Tetrahedral Geometry ◽  
H Nmr ◽  
Antimicrobial Studies ◽  
Mononuclear Complexes ◽  
Uv Visible

A new complexes of the type ML2 and M′L [where M=Cu(II), Co(II), and Ni(II) and M′= Zn(II), Cd(II) and Hg(II)]. L = 3-[(2-hydroxy-quinolin-3-ylmethylene)-amino]-2-phenyl-3H-quinazolin-4-one, (HQMAPQ) Schiff base have been synthesized and characterized by elemental analysis, magnetic susceptibility, molar conductance, IR,1H NMR, UV-Visible and ESR data. The studies indicate the HQMAPQ acts as doubly monodentate bridge for metal(II) ions and form mononuclear complexes. The complexes Ni(II), Co(II) and Cu(II) complexes are found to be octahedral, where as Zn(II), Cd(II) and Hg(II) complexes are four coordinated with tetrahedral geometry. The synthesized ligand and its metal(II) complexes were screened for their antimicrobial activity.

scholarly journals Synthesis, Antibacterial and Antifungal Activity of 5-Aryl Amido-6-Isopropyl-2-(Mercapto/Hydroxy)-4-[(4′-Difluoro Methoxy) (3′-Hydroxy) Phenyl]-1,4-Dihydro Pyrimidine

2015 ◽  
Vol 51 ◽  
pp. 54-60
Author(s):  
Vijay N. Bhadani ◽  
Piyush A. Patel ◽  
Heta D. Purohit ◽  
Dipak M. Purohit
Keyword(s):  
Antifungal Activity ◽  
Ir Spectrum ◽  
Acid Catalyst ◽  
Antibacterial And Antifungal Activity ◽  
Fungal Strains ◽  
H Nmr ◽  
Antibacterial And Antifungal

Various isopropylacetoacetanilides were treated with 4-(difluoromethoxy)-3-hydroxy benzaldehyde and thiourea/urea in the presence of acid catalyst to produce the 1,4-dihydropyrimidine derivatives (4a-5i and 5a-5i) with good yields. All the synthesized compounds were characterized by mass, 1H-NMR and IR spectrum, also evaluated for antibacterial and antifungal activity against two Gram +ve and two Gram-ve bacterial and fungi strains. The compounds 4e, 4g and 5d were found comparatively promising active against all the bacterial and fungal strains.

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