scholarly journals Frequency ofChlamydia trachomatisin Women with Cervicitis in Tehran, Iran

2007 ◽  
Vol 2007 ◽  
pp. 1-4 ◽  
Author(s):  
Farhad B. Hashemi ◽  
Babak Pourakbari ◽  
Javad Zaeimi Yazdi
Keyword(s):  
Screening Program ◽  
Age Groups ◽  
Current Data ◽  
High Morbidity ◽  
Colorimetric Analysis ◽  
Transmitted Infection ◽  
Ct Screening ◽  
Sexually Transmitted ◽  
Coated Plate ◽  
Labeled Probe

Chlamydia trachomatis(CT) is the most common cause of bacterial sexually transmitted infection (STI) worldwide, but current data concerning the prevalence of CT among women in Iran is scarce. Data regarding the frequency of CT infection among Iranian women can help to justify the implementation of a national CT screening program that can reduce the high morbidity associated with sequelae of CT infections by treating infected women. Endocervical secretions from 123 married women (20–55 years) with cervicitis were tested by a PCR-EIA method using primers to amplify a CT-specific plasmid. The digoxigenin-labeled amplicon was measured by hybridization to a biotin-labeled probe and a strepavidin-coated plate, followed by an enzyme-linked colorimetric analysis. Overall frequency of CT infection among women was 17%(21/123). The range of CT frequency among various age groups was 12–25%. The 31–40-year-age group comprised the majority (49%) of CT positive samples, followed by 20–30 year group (33%). Although the 20-to-30-year-old women reported the highest frequency of STI history, they had the lowest relative frequency of CT infection (12%). There is a high frequency of CT infection among women with cervicitis in Tehran, Iran, thus indicating a necessity to implement a routine CT screening program in the major cities of Iran and possibly nationwide. Identification of CT-infected women may prevent its spread, and thereby reduce the high morbidity associated with CT infections among women in Iran.

scholarly journals Prepuce: Phimosis, Paraphimosis, and Circumcision

2011 ◽  
Vol 11 ◽  
pp. 289-301 ◽  
Author(s):  
Yutaro Hayashi ◽  
Yoshiyuki Kojima ◽  
Kentaro Mizuno ◽  
Kenjiro Kohri
Keyword(s):  
Penile Cancer ◽  
Age Groups ◽  
Topical Steroid ◽  
Religious Practice ◽  
Skin Condition ◽  
Rite Of Passage ◽  
Transmitted Infection ◽  
Prophylactic Measure ◽  
Sexually Transmitted ◽  
Male Patients

Phimosis is a condition in which the prepuce cannot be retracted over the glans penis. Actually, physiologic phimosis is common in male patients up to 3 years of age, but often extends into older age groups. Balanoposthitisis a common inflammation occurring in 4–11% of uncircumcised boys. Circumcision is generally undertaken for three reasons: first, as an item of religious practice, typically neonatally although occasionally transpubertally, as a rite of passage; second, as a prophylactic measure against future ailments for the reduction in the risk of penile cancer, urinary tract infection, and sexually transmitted infection; and third, for immediate medical indication. Balanitisxeroticaobliterans is an infiltrative skin condition that causes a pathological phimosis and has been considered to be the only absolute indication for circumcision. Various kinds of effective alternatives to circumcision have been described, including manual retraction therapy, topical steroid therapy, and several variations of preputioplasty. All of these treatments have the ability to retract the foreskin as their goal and do not involve the removal of the entire foreskin. Paraphimosis is a condition in which the foreskin is left retracted. When manipulation is not effective, a dorsal slit should be done, which is usually followed by circumcision.

scholarly journals Suppressive valacyclovir therapy to reduce genital herpes transmission: Good public health policy?

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Paul E Bonnar
Keyword(s):  
Genital Herpes ◽  
Screening Program ◽  
Antiviral Agent ◽  
Suppressive Therapy ◽  
Number Needed To Treat ◽  
Economic Costs ◽  
Transmitted Infection ◽  
Herpes Simplex Viruses ◽  
Sexually Transmitted ◽  
Individual Level

Genital herpes is a widespread sexually transmitted infection caused by the herpes simplex viruses (HSV). Suppressive valacyclovir therapy has been shown to significantly reduce HSV transmission. The benefits and costs of using valacyclovir to reduce transmission in couples discordant for genital herpes will be analyzed in order to better inform decision-making. By reducing transmission, the physical and psychological harms of living with symptomatic genital herpes will be prevented while saving on certain healthcare costs. However, the large number needed to treat and the low symptomatic rate among infected individuals may outweigh these benefits. The costs of trying to achieve a significant reduction in incidence include the psychological harms of identifying asymptomatic individuals through a large screening program and the economic costs of the antiviral agent and screening. When these issues are weighed, the high economic costs render a program to reduce incidence unfeasible. Nevertheless, it is clinically important to consider the consequences of transmission at an individual level. The specific circumstances that influence the decision to use suppressive therapy are identified.

scholarly journals Optimizing Screening for HIV

2020 ◽  
Author(s):  
Antoine Chaillon ◽  
Martin Hoenigl ◽  
Lorri Freitas ◽  
Haruna Feldman ◽  
Winston Tilghman ◽  
...  
Keyword(s):  
At Risk ◽  
Screening Program ◽  
Demographic Data ◽  
The United States ◽  
Hiv Prevalence ◽  
Screening Tests ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
At Risk Populations ◽  
Zip Code

Abstract Background The HIV epidemic is unevenly distributed throughout the United States, even within neighborhoods. This study evaluated how effectively current testing approaches reached persons at risk for HIV infection across San Diego (SD) County, California. Methods HIV case and testing data, sexually transmitted infection (STI) and socio-demographic data for SD County were collected from the SD Health and Human Services Agency and the ‘Early Test’ community-based HIV screening program between 1998 and 2016. Relationships between HIV diagnoses, HIV prevalence, and STI diagnoses with screening at zip code level were evaluated. Results Overall, 379,074 HIV tests were performed. The numbers of HIV tests performed on persons residing in a zip code or region overall strongly correlated with prevalent HIV cases (R2=0.714), new HIV diagnoses (R2=0.798), and STI diagnoses (R2=0.768 [chlamydia],0.836 [gonorrhea], 0.655 [syphilis]) in those regions. Zip codes with the highest HIV prevalence had the highest number of tests per resident and fewest number of tests per diagnosis. Even though most screening tests occurred at fixed venues located in high prevalence areas, screening of residents from lower prevalence areas was mostly proportional to the prevalence of HIV and rates of new HIV and STI diagnoses in those locales. Conclusion This study supported the ability of a small number of standalone testing centers to reach at-risk populations dispersed across SD County. These methods can also be used to highlight geographic areas, or demographic segments that may benefit from more intensive screening.

scholarly journals Expansion of Comprehensive Screening of Male Sexually Transmitted Infection Clinic Attendees with Mycoplasma genitalium and Trichomonas vaginalis Molecular Assessment: a Retrospective Analysis

2016 ◽  
Vol 55 (1) ◽  
pp. 321-325 ◽  
Author(s):  
Erik Munson ◽  
David Wenten ◽  
Sheila Jhansale ◽  
Mary Kay Schuknecht ◽  
Nicki Pantuso ◽  
...  
Keyword(s):  
Sexually Transmitted Infection ◽  
Trichomonas Vaginalis ◽  
Screening Program ◽  
Mycoplasma Genitalium ◽  
Transmitted Infection ◽  
Additional Specimen ◽  
Content Type ◽  
Sexually Transmitted ◽  
High Prevalence ◽  
Infection Clinic

ABSTRACTOf 1,493 encounters of males at a sexually transmitted infection (STI) clinic in a community with a high prevalence of STI,Chlamydia trachomatiswas detected in 8.7% andNeisseria gonorrhoeaewas detected in 6.6%. AdditionalTrichomonas vaginalisandMycoplasma genitaliumscreening found 17.4% and 23.9% of the encounters, respectively, to be positive for STI. STI agents were detected in 13.7% of urine specimens; addition of pharyngeal and rectal collections to the analysis resulted in detection of STI agents in 19.0% and 23.9% of encounters, respectively. A total of 101 (23.8%) encounters of identified STI involved sole detection ofM. genitalium. Expansion of the STI analyte panel (includingM. genitalium) and additional specimen source sampling within a comprehensive STI screening program increase identification of male STI carriers.

scholarly journals Associated factors of willingness to undergo routine chlamydia trachomatis screening among hospital-based patients in Shenzhen, China: a cross-sectional study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Rongxing Weng ◽  
Fuchang Hong ◽  
Chunlai Zhang ◽  
Lizhang Wen ◽  
Xiangsheng Chen ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Intervention Programme ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Ct Screening ◽  
Sexually Transmitted ◽  
One Year ◽  
Correct Understanding

Abstract Background Chlamydia trachomatis (CT) is a common sexually transmitted infection (STI) with significant morbidity. The study aimed to explore the willingness to undergo routine CT screening and its associated factors among hospital-based patients in Shenzhen. Methods We used data from the Shenzhen Gonorrhea and Chlamydia Intervention Programme. Participants were recruited with a stratified purposeful sampling design from 1 April 2018 to 16 May 2018. A structured questionnaire was used to obtain data on baseline characteristics and CT-related participant information. Results Of the 16,546 participants, 64.79% were women, with a mean age of 31.85 ± 7.31 of all participants. Of the participants, 88.78% were willing to undergo routine CT screening. According to multivariate logistic regression analyses, willingness to undergo routine CT screening was associated with the following (P < 0.05): being a woman (AOR = 1.53, 95% CI = 1.34–1.75), one year or more residency in Shenzhen (AOR = 1.64, 95% CI = 1.37–1.95), any secondary education (AOR = 2.46, 95% CI = 1.92–3.15), monthly income ≥ RMB 10,000 (AOR = 1.24, 95% CI = 1.01–1.51), having forgotten CT diagnosis history (AOR = 1.42, 95% CI = 1.12–1.79), without current STI-related symptoms (AOR = 1.24, 95% CI = 1.10–1.41), and having correct understanding of the sequelae of CT infection (AOR = 1.68, 95% CI = 1.39–2.03). Conclusion This study reported high willingness to undergo routine CT screening among hospital-based patients in Shenzhen, and provided evidence for the promotion and the implementation of strategies and recommendations on routine CT screening in China.

scholarly journals Gonococcal Prosthetic Joint Infection

2017 ◽  
Vol 2 (3) ◽  
pp. 160-162 ◽  
Author(s):  
Ian Gassiep ◽  
Bradley Gilpin ◽  
Joel Douglas ◽  
David Siebert
Keyword(s):  
Septic Arthritis ◽  
Antimicrobial Therapy ◽  
Prosthetic Joint Infection ◽  
Joint Infection ◽  
Age Groups ◽  
Gonococcal Infection ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Neisseria Gonorrhoea ◽  
Prosthetic Joint

Abstract. Neisseria gonorrhoea is a common sexually transmitted infection worldwide. Disseminated gonococcal infection is an infrequent presentation and rarely can be associated with septic arthritis. Incidence of this infection is rising, both internationally and in older age groups. We present the first documented case of N. gonorrhoea prosthetic joint infection which was successfully treated with laparoscopic debridement and antimicrobial therapy.

scholarly journals Serodiagnostic Investigation of Syphilis in Taluka Gambat

2020 ◽  
Vol 10 (2) ◽  
pp. 76-81
Author(s):  
Sagheer Hussain Shah ◽  
Agha Asad Noor
Keyword(s):  
Congenital Syphilis ◽  
Age Groups ◽  
Laboratory Diagnosis ◽  
Morbidity Rate ◽  
Age Group ◽  
Serum Samples ◽  
Transmitted Infection ◽  
Serological Method ◽  
Female Population ◽  
Sexually Transmitted

Background: Syphilis is a chronic and sexually transmitted infection, caused by Treponema pallidum. Taluka Gambat is an under developing rural area of District Khairpur, Sindh having higher poverty rate. This study was undertaken to assess the morbidity rate of syphilis and awareness about this disease in the population of Gambat. Objectives: To investigate the prevalence of syphilis in various age groups of male and female population of Taluka Gambat to review the frequency of occurrence of syphilis. Methodology: This work was done using conventional serological method by collecting data and laboratory diagnosis. Total 437 serum samples from different private and public health units, dispensaries and hospitals in Taluka Gambat were collected between October 2016 to March 2017 and subjected to qualitative testing by VDRL-Immune Chromatography test. Results: Out of 437 samples, 80 samples (18%) were reactive in adults of 30-45 years of age and one sample showed positive case in 9 months old boy indicating congenital syphilis (0.2%) whereas 373 stood non-reactive.  Our results showed a 14% prevalence of syphilis in Taluka Gambat in the age group between 30-45 years of age and 0.2% congenital syphilis. It is an alarming situation due to lack of diagnostic, treatment facilities and awareness about sexually transmitted diseases (STDs). Conclusion: It is concluded that syphilis is found more or less in all age groups. The highest incidence is observed in population of age group between 30-40 years in Taluka Gambat. Majority infections were found in immunocompromised patients owing to drug abuse and having multiple sex partners.

A Novel Public Library-Based Sexually Transmitted Infection Screening Program for Younger High-Risk Groups in Omaha, Nebraska, USA

2015 ◽  
Vol 41 (2) ◽  
pp. 289-295
Author(s):  
Shirley F. Delair ◽  
Elizabeth R. Lyden ◽  
Anne L. O’Keefe ◽  
Kari A. Simonsen ◽  
Sherri R. Nared ◽  
...  
Keyword(s):  
High Risk ◽  
Sexually Transmitted Infection ◽  
Screening Program ◽  
Public Library ◽  
Risk Groups ◽  
Transmitted Infection ◽  
Sexually Transmitted

scholarly journals 433. Implementation of an Emergency Department Syphilis Screening Program

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S216-S216
Author(s):  
Tasleem Chechi ◽  
Allyson C Sage ◽  
Nam Tran ◽  
Sarah Waldman ◽  
Larissa S May
Keyword(s):  
Best Practice ◽  
Congenital Syphilis ◽  
Screening Program ◽  
Turnaround Time ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Sti Testing ◽  
Increased Risk ◽  
High Prevalence ◽  
Syphilis Screening

Abstract Background Syphilis incidence across all regions of California increased by 22% compared with 2016 cases; with the largest number of chlamydia, gonorrhea, syphilis, and congenital syphilis cases among all states (CDC 2017). The USPSTF recommends targeted syphilis screening in patients at increased risk. However, in emergency departments (EDs) targeted syphilis screening is not routinely performed even when patients present for concerns of a sexually transmitted infection (STI). The purpose of this program was to implement routine syphilis screening among ED patients being tested for chlamydia and gonorrhea (CT/GC) through the use of an EHR enhancement to maximize the number of new syphilis diagnoses. Methods From November 27, 2018 to March 31, 2019, EHR-based syphilis screening was implemented in a quaternary care ED in Northern California serving urban and rural populations. EMR best practice alerts (BPA) were developed and populated on patients receiving STI testing. Syphilis testing employed a reverse sequence algorithm, which is suggested for high prevalence settings and provides rapid turnaround time. Patients were excluded if they opted out from testing. We determined the proportion of all CT/GC tested patients who underwent syphilis screening and the prevalence of syphilis among this group. Results During a four-month period, 649 ED patients with suspected STI received a BPA to screen for syphilis. Of those, 425 patients (65.5%) were screened for syphilis, 22 had a reactive IgG/IgM and RPR, while 5 patients had a reactive IgG/IgM and a nonreactive RPR which required a TPPA test to detect their infection. Fourteen of the 22 patients with a reactive RPR had titers of 1:32 or higher. Nine (32%) of those with a positive CT/GC test tested positive for syphilis. Conclusion Implementation of a syphilis screening program in patients undergoing testing for other STIs yielded 28 new diagnoses compared with those tested prior to the screening in 2018. Introducing an automated EMR-based syphilis screening program is an effective method to maximize syphilis screening in all ED patients seeking treatment for STIs. The screening data suggest that the majority of patients undergoing STI testing in our ED are not screened for syphilis, yet the prevalence of infection in those screened is substantial. Disclosures All authors: No reported disclosures.

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