scholarly journals Puerperal Fever and Neonatal Pleural Empyema and Bacteremia Caused by Group A Streptococcus

1998 ◽  
Vol 9 (3) ◽  
pp. 185-188 ◽  
Author(s):  
Laurance Lequier ◽  
Wendy L Vaudry
Keyword(s):  
Chest Tube ◽  
Genomic Sequence ◽  
Puerperal Fever ◽  
Group A Streptococcus ◽  
Pleural Empyema ◽  
Early Postpartum Period ◽  
Early Postpartum ◽  
Group A ◽  
Polymerase Chain

A term neonate developed early onset of sepsis and pleural empyema with group A streptococcus. Her mother also became septic with group A streptococcus in the early postpartum period. The infant required initial chest tube drainage. After reaccumulation of pleural fluid after removal of the chest tube, a thoracotomy with decortication was performed. The isolates of group A streptococcus were analyzed and found to be identical serotypes of the same bacterium. The serotyping revealed both to be M type 1, T pattern 1. Polymerase chain reaction detected the genomic sequence for streptococcal pyrogenic exotoxin A and B in both isolates. With the increase in invasive streptococcal infections in the community, serious perinatal infections may become more frequent.

Change in Bacterial Causes of Community-Acquired Parapneumonic Effusion and Pleural Empyema in Children 6 Years After 13-Valent Pneumococcal Conjugate Vaccine Implementation

2018 ◽  
Vol 8 (5) ◽  
pp. 474-477 ◽  
Author(s):  
Fouad Madhi ◽  
Corinne Levy ◽  
Laurence Morin ◽  
Philippe Minodier ◽  
François Dubos ◽  
...  
Keyword(s):  
Conjugate Vaccine ◽  
Pneumococcal Conjugate Vaccine ◽  
Group A Streptococcus ◽  
Pneumococcal Infection ◽  
Pleural Empyema ◽  
Parapneumonic Effusion ◽  
Before And After ◽  
Group A

AbstractWe describe here changes in the bacterial causes of pleural empyema before and after implementation of the 13-valent pneumococcal conjugate vaccine (PCV13) program in France (2009–2017). For 220 (39.3%) of 560 children, a bacterial cause was found. The frequency of pneumococcal infection decreased during the study from 79.1% in 2009 to 36.4% in 2017 (P < .001). Group A streptococcus is now the leading cause of documented empyema (45.5%).

Detection of Group A Streptococcus in the Saliva of Children Presenting With Pharyngitis Using the cobas Liat PCR System

2020 ◽  
Vol 59 (9-10) ◽  
pp. 856-858
Author(s):  
Gregory DeMuri ◽  
Ellen R. Wald
Keyword(s):  
Polymerase Chain Reaction ◽  
Pilot Study ◽  
Group A Streptococcus ◽  
Point Of Care ◽  
Sampling Techniques ◽  
Chain Reaction ◽  
Point Of Care Test ◽  
Group A ◽  
Increased Sensitivity ◽  
Polymerase Chain

Rapid turnaround real-time polymerase chain reaction (PCR) has recently become available as a point-of-care test for group A Streptococcus (GAS) in children presenting with pharyngitis. Our aim in this pilot study was to determine if GAS can be detected in the saliva of children with sore throat using swabs inoculated by children sucking on them as they would a lollipop. Twenty children with positive rapid antigen detection tests for GAS from pharyngeal swabs were enrolled. Pharyngeal and lollipop samples underwent PCR testing using the cobas Liat system. All 20 pharyngeal swabs were positive; 19 of 20 lollipop samples were positive. The increased sensitivity of the new PCR kits for GAS may permit use of less invasive and more comfortable sampling techniques for diagnosis.

When should clinicians suspect group A streptococcus empyema in children? A multicentre case–control study in French tertiary care centres

2016 ◽  
Vol 101 (8) ◽  
pp. 731-735 ◽  
Author(s):  
Sophia Bellulo ◽  
Julie Sommet ◽  
Corinne Lévy ◽  
Yves Gillet ◽  
Laure Hees ◽  
...  
Keyword(s):  
Group A Streptococcus ◽  
Tertiary Care ◽  
Pleural Empyema ◽  
Circulatory Failure ◽  
Short Term ◽  
Invasive Group ◽  
Invasive Diseases ◽  
Group A ◽  
Few Data ◽  
Control Study

BackgroundThe incidence of invasive group A streptococcus (GAS) infections is increasing worldwide, whereas there has been a dramatic decrease in pneumococcal invasive diseases. Few data describing GAS pleural empyema in children are available.ObjectiveTo describe the clinical and microbiological features, management and outcome of GAS pleural empyema in children and compare them with those of pneumococcal empyema.Design, setting and patientsFifty children admitted for GAS pleural empyema between January 2006 and May 2013 to 8 hospitals participating in a national pneumonia survey were included in a descriptive study and matched by age and centre with 50 children with pneumococcal empyema.ResultsThe median age of the children with GAS pleural empyema was 2 (range 0.1–7.6) years. Eighteen children (36%) had at least one risk factor for invasive GAS infection (corticosteroid use and/or current varicella). On admission, 37 patients (74%) had signs of circulatory failure, and 31 (62%) had a rash. GAS was isolated from 49/50 pleural fluid samples and from one blood culture. The commonest GAS genotype was emm1 (n=17/22). Two children died (4%). Children with GAS empyema presented more frequently with a rash (p<0.01), signs of circulatory failure (p=0.01) and respiratory disorders (p=0.02) and with low leucocyte levels (p=0.04) than children with pneumococcal empyema. Intensive care unit admissions (p<0.01), drainage procedures (p=0.04) and short-term complications (p=0.01) were also more frequent in patients with GAS empyema.ConclusionsPleural empyema following varicella or presenting with rash, signs of circulatory failure and leucopenia may be due to GAS. These features should prompt the addition to treatment of an antitoxin drug, such as clindamycin.

NEONATAL PLEURAL EMPYEMA CAUSED BY GROUP A STREPTOCOCCUS

1994 ◽  
Vol 13 (7) ◽  
pp. 671-672 ◽  
Author(s):  
K. A. Nathavitharana ◽  
M. Watkinson
Keyword(s):  
Group A Streptococcus ◽  
Pleural Empyema ◽  
Group A

scholarly journals Whole-Genome Sequence of an Indian Group A Streptococcus emm Type 1-2 Strain Isolated from a Blood Sample in North India

2020 ◽  
Vol 9 (19) ◽  
Author(s):  
Vivek Sagar ◽  
Anuradha Chakraborti ◽  
Rajesh Kumar
Keyword(s):  
Partial Information ◽  
Group A Streptococcus ◽  
North India ◽  
Whole Genome Sequence ◽  
Accession Number ◽  
Genetic Characteristics ◽  
Ncbi Accession ◽  
Group A ◽  
Ncbi Accession Number

Group A Streptococcus emm type 1-2 is more prevalent than emm type 1 in India. Only partial information is available about the genetic characteristics of this type. Here, genome sequencing of emm type 1-2 strain 1085 (from blood) was conducted. A contig 2,010,300 bp long, with a total of 1,877 annotated proteins, was obtained (NCBI accession number CP047120, assembly accession number ASM983284v1).

scholarly journals A humán parechovírusok klinikai jelentősége súlyos újszülött- és csecsemőkori fertőzésekben hazánkban

2019 ◽  
Vol 160 (10) ◽  
pp. 386-395
Author(s):  
Ákos Boros ◽  
Zsófia Hamarics ◽  
Hajnalka Fenyvesi ◽  
Zoltán Liptai ◽  
Zoltán Nyul ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Neurological Symptoms ◽  
Human Parechovirus ◽  
Faecal Samples ◽  
Group A ◽  
Polymerase Chain ◽  
Group B ◽  
Loss Of Appetite ◽  
Leading Symptom

Abstract: Introduction: Most human parechovirus (HPeV, family Picornaviridae) infections are asymptomatic but may cause gastroenteritis in children. New reports show that HPeVs can be associated with severe central nervous system symptoms and sepsis-like syndromes in infants. The clinical significance of HPeVs in Hungary has not been investigated before. Aim: The aim of this study was to detect genotype HPeV in faecal samples of children and analysis of the clinical symptoms. Method: For the detection and genotyping of HPeV strains, reverse transcription–polymerase chain reaction and sequencing methods were used from faecal samples of children with gastroenteritis divided into three groups: group A) hospitalised children younger than 10 years (n = 75); group B) 0–12 months infants (n = 237) and group C) children less than 18 years of age with sepsis-like/neurological symptoms (n = 105) were tested. Results: Three HPeV positive samples (3/75, 4%) were found in group A, two of them belong to the HPeV type 1, the third was non-typeable. All positive samples were from infants of 7 to 11 months of age. In group B, HPeV was detected in 6.8% (16/237) of the samples. Five were HPeV1, six were HPeV3 and five were non-typeable. While most of the infants with HPeV1 (4/5) did not require hospitalisation, 83% of the HPeV3 infected infants (5/6) did. Five (4.8%) HPeV strains detected from children less than 18 years of age with sepsis-like/neurological symptoms (group C) belonged to HPeV1 (three) and HPeV3 (two). All positive samples were from hospitalised infants less than 2 months of age. Conclusion: HPeV1 infections are less severe in infants than HPeV3 infections. The leading symptom of HPeV1 was diarrhoea, although in infants less than 1–2 months neurological symptoms (somnolence, lassitude) were also present. HPeV3 infections were more common among newborns. The main symptoms of severe HPeV3 infection are: gastroenteritis (7/8), fever ≥38 °C (6/7), loss of appetite (6/7), rash (4/7), somnolence/lassitude (3/7), sepsis-like syndrome (3/7) and respiratory symptoms (2/7). Orv Hetil. 2019; 160(10): 386–395.

scholarly journals Type 1 Diabetes Mellitus Diagnosed during Follow-up of Gestational Diabetes Mellitus in the Early Postpartum Period

2018 ◽  
Vol 57 (23) ◽  
pp. 3413-3418
Author(s):  
Toshiyuki Ikeoka ◽  
Ayaka Sako ◽  
Genpei Kuriya ◽  
Hiroshi Yamashita ◽  
Ichiro Yasuhi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Type 1 Diabetes Mellitus ◽  
Postpartum Period ◽  
Early Postpartum Period ◽  
Early Postpartum

Neonatal pleural empyema caused byemmtype 6 group A streptococcus

2013 ◽  
Vol 55 (4) ◽  
pp. 519-521
Author(s):  
Fumikatsu Nohara ◽  
Ken Nagaya ◽  
Hiroko Asai ◽  
Etsushi Tsuchida ◽  
Toshio Okamoto ◽  
...  
Keyword(s):  
Group A Streptococcus ◽  
Pleural Empyema ◽  
Group A
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