Facilitated Hexose Transporters: New Perspectives on Form and Function

Physiology ◽  
2007 ◽  
Vol 22 (4) ◽  
pp. 234-240 ◽  
Author(s):  
Andrei R. Manolescu ◽  
Kate Witkowska ◽  
Adam Kinnaird ◽  
Tara Cessford ◽  
Chris Cheeseman

The recent sequencing of the human genome has resulted in the addition of nine new hGLUT isoforms to the SLC2A family, many of which have widely varying substrate specificity, kinetic behavior, and tissue distribution. This review examines some new hypotheses related to the structure and function of these proteins.

Author(s):  
Karen J. Esler ◽  
Anna L. Jacobsen ◽  
R. Brandon Pratt

The archetypal shrub type that dominates most of the regions that experience mediterranean-type climate (MTC) is an evergreen shrub with thick and leathery leaves (sclerophyllous). The occurrence of large stands of such shrubs in all MTC regions led early biogeographers to hypothesize that the MTC selects for this growth form and leaf type and that this had led to convergent evolution (see Chapters 1 and 2). This hypothesis has received considerable research interest and continues to be examined. In this chapter we consider the structure and physiology of these archetypal MTC region shrub species and examine evidence for convergent evolution in their structure and function. We also assess the key adaptive traits that enable the shrub species that compose mediterranean-type vegetation (MTV) communities to thrive in MTC regions.


Author(s):  
Vienny N. Nguyen ◽  
Blaine W. Lilly ◽  
Carlos E. Castro

Insects as mechanical systems have been optimized for form and function over millions of years. Ants, in particular, can lift and carry extremely heavy loads relative to their body mass. Loads are lifted with the mouthparts, transferred through the neck joint to the thorax, and distributed over six legs and feet that anchor to the supporting surface. While previous research efforts have explored attachment mechanisms of the feet, little is known about the mechanical design of the neck — the single joint that connects the load path from the thorax to the head. This work combines mechanical testing, computed tomography (CT) and scanning electron microscope (SEM) imaging, and computational modeling to better understand the mechanical structure-function relation of the ant neck joint.


2000 ◽  
Vol 65 (4) ◽  
pp. 207-227 ◽  
Author(s):  
Svetlana Trivic ◽  
Vladimir Leskovac

1. Introduction 2. Isoenzymes of YADH 3. Substrate specificity 4. Kinetic mechanism 5. Primary structure 6. The active site 7. Mutations in the yeast enzyme 8. Chemical mechanism 9. Binding of coenzymes 10. Hydride transfer <br><br><font color="red"><b> This article has been corrected. Link to the correction <u><a href="http://dx.doi.org/10.2298/JSC0008609E">10.2298/JSC0008609E</a><u></b></font>


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kamariah Kamariah ◽  
Ngalimun Ngalimun

The purpose of this research is to study the structure and function of the Banjar regionalsongs. Besides carrying out the mission of revitalizing Banjar culture which has begun tobecome extinct along with the times. This research uses descriptive method so the results of thisstudy are the results of research on Banjar by H. Anang Ardiansyah. For accurate andunderstandable analysis data, this study uses an objective method, which is based on the literarywork itself. This method is expected to reveal the form and function contained in the Banjarsong.The structure of the Banjar song by H. Anang Ardiansyah can be changed into two,namely the repetition of parts and repetition with changes. Bait full repeat loop. Repetition withthe changes requested in the repetition of feedback in the first few lines is the same, but inseveral lines after the change in feedback. This research also succeeded in formulating fourfunctions of the Banjar song, namely the function of educating or helping, entertaining,criticizing, and expressing feelings.


2005 ◽  
Vol 33 (1) ◽  
pp. 108-111 ◽  
Author(s):  
E. Theodoratou ◽  
R. Huber ◽  
A. Böck

Hydrogenase maturation endopeptidases catalyse the terminal step in the maturation of the large subunit of [NiFe]-hydrogenases. They remove a C-terminal extension from the precursor of the subunit, triggering a conformational switch that results in the bridging of the Fe and Ni atoms of the metal centre via the thiolate of a cysteine residue and in closure of the centre. This review summarizes what is known about the structure of the protein, its substrate specificity and its possible reaction mechanism.


Author(s):  
Robert L. Nussbaum ◽  
Roderick R. McInnes ◽  
Huntington F. Willard ◽  
Ada Hamosh

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