scholarly journals Neural Rate and Timing Cues for Detection and Discrimination of Amplitude-Modulated Tones in the Awake Rabbit Inferior Colliculus

2007 ◽  
Vol 97 (1) ◽  
pp. 522-539 ◽  
Author(s):  
Paul C. Nelson ◽  
Laurel H. Carney
Keyword(s):  
Inferior Colliculus ◽  
Dynamic Range ◽  
Modulation Depth ◽  
Average Rate ◽  
Modulation Frequency ◽  
Detection Threshold ◽  
Depth Functions ◽  
Depth Discrimination ◽  
High Modulation ◽  
Envelope Processing

Neural responses to amplitude-modulated (AM) tones in the unanesthetized rabbit inferior colliculus (IC) were studied in an effort to establish explicit relationships between physiological and psychophysical measures of temporal envelope processing. Specifically, responses to variations in modulation depth ( m) at the cell’s best modulation frequency, with and without modulation maskers, were quantified in terms of average rate and synchronization to the envelope over the entire perceptual dynamic range of depths. Statistically significant variations in the metrics were used to define neural AM detection and discrimination thresholds. Synchrony emerged at modulation depths comparable with psychophysical AM detection sensitivities in some neurons, whereas the lowest rate-based neural thresholds could not account for psychoacoustical thresholds. The majority of rate thresholds (85%) were −10 dB or higher (in 20 log m), and 16% of the population exhibited no systematic dependence of average rate on m. Neural thresholds for AM detection did not decrease systematically at higher SPLs (as observed psychophysically): thresholds remained constant or increased with level for most cells tested at multiple sound-pressure levels (SPLs). At depths higher than the rate-based detection threshold, some rate modulation-depth functions were sufficiently steep with respect to the across-trial variability of the rate to predict depth discrimination thresholds as low as 1 dB (comparable with the psychophysics). Synchrony, on the other hand, did not vary systematically with m in many cells at high modulation depths. A simple computational model was extended to reproduce several features of the modulation frequency and depth dependence of both transient and sustained pure-tone responders.

scholarly journals Modulation depth discrimination by cochlear implant users

2021 ◽  
Author(s):  
Jessica Monaghan ◽  
Robert P. Carlyon ◽  
John M. Deeks
Keyword(s):  
Speech Processing ◽  
Dynamic Range ◽  
Modulation Depth ◽  
High Rate ◽  
Backward Masking ◽  
Pulse Trains ◽  
Processing Strategies ◽  
Depth Discrimination ◽  
Variable Point ◽  
Forced Choice Task

Cochlear implants (CIs) convey the amplitude envelope of speech by modulating high-rate pulse-trains. However, not all of the envelope may be necessary to perceive amplitude modulations (AM); the effective envelope depth may be limited by forward and backward masking from the envelope peaks. Three experiments used modulated pulse-trains to measure which portions of the envelope can be effectively processed by CI users as a function of AM frequency. Experiment 1 used a three-interval forced-choice task to test the ability of CI users to discriminate less-modulated pulse trains from a fully-modulated standard, without controlling for loudness. The stimuli in Experiment 2 were identical, but a two-interval task was used in which participants were required to choose the less-modulated interval, ignoring loudness. Catch trials, in which judgements based on level or modulation depth would give opposing answers were included. Experiment 3 employed novel stimuli whose modulation envelope could be modified below a variable point in the dynamic range, without changing the loudness of the stimulus. Overall, results showed that substantial portions of the envelope are not accurately encoded by CI users. Experiment 1, where loudness cues were available, participants on average were insensitive to changes in the bottom 30% of their dynamic range. In Experiment 2, where loudness was controlled, participants appeared insensitive to changes in the bottom 50% of the dynamic range. In Experiment 3, participants were insensitive to changes in the bottom 80% of the dynamic range. We discuss potential reasons for this insensitivity and implications for CI speech-processing strategies.

Neural Processing of Amplitude-Modulated Sounds

2004 ◽  
Vol 84 (2) ◽  
pp. 541-577 ◽  
Author(s):  
P. X. JORIS ◽  
C. E. SCHREINER ◽  
A. REES
Keyword(s):  
Modulation Depth ◽  
Average Rate ◽  
Modulation Frequency ◽  
Limited Range ◽  
Neural Processing ◽  
Neural Responses ◽  
Critical Stimulus ◽  
Stimulus Attribute ◽  
Neural Architecture ◽  
Physiological Properties

Joris, P. X., C. E. Schreiner, and A. Rees. Neural Processing of Amplitude-Modulated Sounds. Physiol Rev 84: 541–577, 2004; 10.1152/physrev.00029.2003.—Amplitude modulation (AM) is a temporal feature of most natural acoustic signals. A long psychophysical tradition has shown that AM is important in a variety of perceptual tasks, over a range of time scales. Technical possibilities in stimulus synthesis have reinvigorated this field and brought the modulation dimension back into focus. We address the question whether specialized neural mechanisms exist to extract AM information, and thus whether consideration of the modulation domain is essential in understanding the neural architecture of the auditory system. The available evidence suggests that this is the case. Peripheral neural structures not only transmit envelope information in the form of neural activity synchronized to the modulation waveform but are often tuned so that they only respond over a limited range of modulation frequencies. Ascendingthe auditory neuraxis, AM tuning persists but increasingly takes the form of tuning in average firing rate, rather than synchronization, to modulation frequency. There is a decrease in the highest modulation frequencies that influence the neural response, either in average rate or synchronization, as one records at higher and higher levels along the neuraxis. In parallel, there is an increasing tolerance of modulation tuning for other stimulus parameters such as sound pressure level, modulation depth, and type of carrier. At several anatomical levels, consideration of modulation response properties assists the prediction of neural responses to complex natural stimuli. Finally, some evidence exists for a topographic ordering of neurons according to modulation tuning. The picture that emerges is that temporal modulations are a critical stimulus attribute that assists us in the detection, discrimination, identification, parsing, and localization of acoustic sources and that this wide-ranging role is reflected in dedicated physiological properties at different anatomical levels.

scholarly journals Sustained envelope periodicity representations are associated with speech-in-noise performance in difficult listening conditions for younger and older adults

2019 ◽  
Vol 122 (4) ◽  
pp. 1685-1696 ◽  
Author(s):  
Carolyn M. McClaskey ◽  
James W. Dias ◽  
Kelly C. Harris
Keyword(s):  
Older Adults ◽  
Modulation Depth ◽  
Phase Locking ◽  
Modulation Frequency ◽  
Normal Hearing ◽  
Spectral Amplitude ◽  
Noise Performance ◽  
Speech In Noise ◽  
Envelope Processing ◽  
The Relationship

Temporal modulations are an important part of speech signals. An accurate perception of these time-varying qualities of sound is necessary for successful communication. The current study investigates the relationship between sustained envelope encoding and speech-in-noise perception in a cohort of normal-hearing younger (ages 18–30 yr, n = 22) and older adults (ages 55–90+ yr, n = 35) using the subcortical auditory steady-state response (ASSR). ASSRs were measured in response to the envelope of 400-ms amplitude-modulated (AM) tones with 3,000-Hz carrier frequencies and 80-Hz modulation frequencies. AM tones had modulation depths of 0, −4, and −8 dB relative to m = 1 ( m = 1, 0.631, and 0.398, respectively). The robustness, strength at modulation frequency, and synchrony of subcortical envelope encoding were quantified via time-domain correlations, spectral amplitude, and phase-locking value, respectively. Speech-in-noise ability was quantified via the QuickSIN test in the 0- and 5-dB signal-to-noise (SNR) conditions. All ASSR metrics increased with increasing modulation depth and there were no effects of age group. ASSR metrics in response to shallow modulation depths predicted 0-dB speech scores. Results demonstrate that sustained amplitude envelope processing in the brainstem relates to speech-in-noise abilities, but primarily in difficult listening conditions at low SNRs. These findings furthermore highlight the utility of shallow modulation depths for studying temporal processing. The absence of age effects in these data demonstrate that individual differences in the robustness, strength, and specificity of subcortical envelope processing, and not age, predict speech-in-noise performance in the most difficult listening conditions. NEW & NOTEWORTHY Failure to correctly understand speech in the presence of background noise is a significant problem for many normal-hearing adults and may impede healthy communication. The relationship between sustained envelope encoding in the brainstem and speech-in-noise perception remains to be clarified. The present study demonstrates that the strength, specificity, and robustness of the brainstem’s representations of sustained stimulus periodicity relates to speech-in-noise perception in older and younger normal-hearing adults, but only in highly challenging listening environments.

Sources of the Scalp-Recorded Amplitude-Modulation Following Response

2002 ◽  
Vol 13 (04) ◽  
pp. 188-204 ◽  
Author(s):  
Shigeyuki Kuwada ◽  
Julia S. Anderson ◽  
Ranjan Batra ◽  
Douglas C. Fitzpatrick ◽  
Natacha Teissier ◽  
...  
Keyword(s):  
Animal Model ◽  
Amplitude Modulation ◽  
Single Unit ◽  
Modulation Frequency ◽  
Multiple Sources ◽  
High Modulation ◽  
Before And After ◽  
Single Unit Recordings ◽  
Composite Response ◽  
The Brain

The scalp-recorded amplitude-modulation following response (AMFR)” is gaining recognition as an objective audiometric tool, but little is known about the neural sources that underlie this potential. We hypothesized, based on our human studies and single-unit recordings in animals, that the scalp-recorded AMFR reflects the interaction of multiple sources. We tested this hypothesis using an animal model, the unanesthetized rabbit. We compared AMFRs recorded from the surface of the brain at different locations and before and after the administration of agents likely to enhance or suppress neural generators. We also recorded AMFRs locally at several stations along the auditory neuraxis. We conclude that the surface-recorded AMFR is indeed a composite response from multiple brain generators. Although the response at any modulation frequency can reflect the activity of more than one generator, the AMFRs to low and high modulation frequencies appear to reflect a strong contribution from cortical and subcortical sources, respectively.

scholarly journals Film Thickness-Profile Measurement Using Iterative Peak Separation Structured Illumination Microscopy

2021 ◽  
Vol 11 (7) ◽  
pp. 3023
Author(s):  
Kejun Yang ◽  
Chenhaolei Han ◽  
Jinhua Feng ◽  
Yan Tang ◽  
Zhongye Xie ◽  
...  
Keyword(s):  
Modulation Depth ◽  
Thickness Distribution ◽  
Detection Threshold ◽  
Profile Measurement ◽  
Structured Illumination ◽  
Structured Illumination Microscopy ◽  
Separation Algorithm ◽  
Peak Separation ◽  
Lower Detection ◽  
Depth Response

The surface and thickness distribution measurement for transparent film is of interest for electronics and packaging materials. Structured illumination microscopy (SIM) is a prospective technique for measuring film due to its high accuracy and efficiency. However, when the distance between adjacent layers becomes close, the peaks of the modulation depth response (MDR) start to overlap and interfere with the peak extraction, which restricts SIM development in the field of film measurement. In this paper, an iterative peak separation algorithm is creatively applied in the SIM-based technique, providing a precise peak identification even as the MDR peaks overlap and bend into one. Compared with the traditional method, the proposed method has a lower detection threshold for thickness. The experiments and theoretical analysis are elaborated to demonstrate the feasibility of the mentioned method.

scholarly journals Contribution of onset/offset information of modulation to amplitude modulation depth discrimination

2008 ◽  
Vol 123 (5) ◽  
pp. EL111-EL115 ◽  
Author(s):  
Derek R. Edwards ◽  
Jungmee Lee ◽  
Jennifer Andrews ◽  
Aileen Wong
Keyword(s):  
Amplitude Modulation ◽  
Modulation Depth ◽  
Depth Discrimination

Quantitative FM Spectroscopy at High Temperatures: The Detection of 1CH2 behind Shock Waves

2000 ◽  
Vol 214 (12) ◽  
Author(s):  
G. Friedrichs ◽  
H.Gg. Wagner
Keyword(s):  
High Temperature ◽  
Shock Waves ◽  
High Temperatures ◽  
Frequency Modulation ◽  
Modulation Frequency ◽  
Optical Power ◽  
Time Resolved ◽  
Signal Conversion ◽  
High Modulation ◽  
Singlet Methylene

The technique of time resolved frequency modulation (FM) spectroscopy has been shown to provide a very sensitive means to detect small radicals behind shock waves. Features of high temperature FM spectroscopy behind shock waves will be discussed and a general signal conversion procedure to carry out quantitative concentration measurements will be presented.Using a high modulation frequency, a high modulation index and high total optical power, singlet methylene radicals (α

Modelling of Io’s Atmosphere for the IVO Mission

2021 ◽  
Author(s):  
Peter Wurz ◽  
Audrey Vorburger ◽  
Alfred McEwen ◽  
Kathy Mandt ◽  
Ashley Davies ◽  
...  
Keyword(s):  
Mass Loss ◽  
Dynamic Range ◽  
Detection Threshold ◽  
Mass Range ◽  
Mission Design ◽  
Integration Time ◽  
Many Worlds ◽  
Initial State ◽  
Atmospheric Escape ◽  
Tidal Heating

<p>The Io Volcano Observer (IVO) is a proposed NASA Discovery-class mission (currently in Phase A), that would launch<span> in early 2029, arrive at </span> Jupiter in the early 2033, and perform ten flybys of Io while in Jupiter's orbit. IVO's mission motto is to 'follow the heat', shedding light onto tidal heating as a fundamental planetary process. Specifically, IVO will determine (i) how and where heat is generated in Io's interior, (ii) how heat is transported to the surface, and (iii) how Io has evolved with time. The answers to these questions will fill fundamental gaps in the current understanding of the evolution and habitability of many worlds across our Solar System and beyond where tidal heating plays a key role, and will give us insight into how early Earth, Moon, and Mars may have worked.</p><p>One of the five key science questions IVO will be addressing is determining Io's mass loss via atmospheric escape. Understanding Io's mass loss today will offer information on how the chemistry of Io has been altered from its initial state and would provide useful clues on how atmospheres on other bodies have evolved over time. IVO plans on measuring Io's mass loss in situ with the Ion and Neutral Mass Spectrometer (INMS), a successor to the instrument currently being built for the JUpiter Icy moons Explorer (JUICE). INMS will measure neutrals and ions in the mass range 1 – 300 u, with a mass resolution (M/ΔM) of 500, a dynamic range of > 10<sup>5</sup>, a detection threshold of 100 cm<sup>–3</sup> for an integration time of 5 s, and a cadence of 0.5 – 300 s per spectrum.</p><p>In preparation for IVO, we model atmospheric density profiles of species known and expected to be present on Io's surface from both measurements and previous modelling efforts. Based on the IVO mission design, we present three different measurement scenarios for INMS we expect to encounter at Io based on the planned flybys: (i) a purely sublimated atmosphere, (ii) the 'hot' atmosphere generated by lava fields, and (iii) the plume gases resulting from volcanic activity. We calculate the expected mass spectra to be recorded by INMS during these flybys for these atmospheric scenarios.</p>

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