Effect of a divided caffeine dose on endurance cycling performance, postexercise urinary caffeine concentration, and plasma paraxanthine

2003 ◽  
Vol 94 (4) ◽  
pp. 1557-1562 ◽  
Author(s):  
Kylie J. Conway ◽  
Rhonda Orr ◽  
Stephen R. Stannard

This study compared the effects of a single and divided dose of caffeine on endurance performance and on postexercise urinary caffeine and plasma paraxanthine concentrations. Nine male cyclists and triathletes cycled for 90 min at 68% of maximal oxygen uptake, followed by a self-paced time trial (work equivalent to 80% of maximal oxygen uptake workload over 30 min) with three randomized, balanced, and double-blind interventions: 1) placebo 60 min before and 45 min into exercise (PP); 2) single caffeine dose (6 mg/kg) 60 min before exercise and placebo 45 min into exercise (CP); and 3) divided caffeine dose (3 mg/kg) 60 min before and 45 min into exercise (CC). Time trial performance was unchanged with caffeine ingestion ( P = 0.08), but it tended to be faster in the caffeine trials (CP: 24.2 min and CC: 23.4 min) compared with placebo (PP: 28.3 min). Postexercise urinary caffeine concentration was significantly lower in CC (3.8 μg/ml) compared with CP (6.8 μg/ml). Plasma paraxanthine increased in a dose-dependent fashion and did not peak during exercise. In conclusion, dividing a caffeine dose provides no ergogenic effect over a bolus dose but reduces postexercise urinary concentration.

2009 ◽  
Vol 19 (6) ◽  
pp. 624-644 ◽  
Author(s):  
Sara Dean ◽  
Andrea Braakhuis ◽  
Carl Paton

Researchers have long been investigating strategies that can increase athletes’ ability to oxidize fatty acids and spare carbohydrate, thus potentially improving endurance capacity. Green-tea extract (epigallocatechin-3-gallate; EGCG) has been shown to improve endurance capacity in mice. If a green-tea extract can stimulate fat oxidation and as a result spare glycogen stores, then athletes may benefit through improved endurance performance. Eight male cyclists completed a study incorporating a 3-way crossover, randomized, placebo-controlled, double-blinded, diet-controlled research design. All participants received 3 different treatments (placebo 270 mg, EGCG 270 mg, and placebo 270 mg + caffeine 3 mg/kg) over a 6-day period and 1 hr before exercise testing. Each participant completed 3 exercise trials consisting of 60 min of cycling at 60% maximum oxygen uptake (VO2max) immediately followed by a self-paced 40-km cycling time trial. The study found little benefit in consuming green-tea extract on fat oxidation or cycling performance, unlike caffeine, which did benefit cycling performance. The physiological responses observed during submaximal cycling after caffeine ingestion were similar to those reported previously, including an increase in heart rate (EGCG 147 ± 17, caffeine 146 ± 19, and placebo 144 ± 15 beats/min), glucose at the 40-min exercise time point (placebo 5.0 ± 0.8, EGCG 5.4 ± 1.0, and caffeine 5.8 ± 1.0 mmol/L), and resting plasma free fatty acids and no change in the amount of carbohydrate and fat being oxidized. Therefore, it was concluded that green-tea extract offers no additional benefit to cyclists over and above those achieved by using caffeine.


2012 ◽  
Vol 37 (4) ◽  
pp. 637-645 ◽  
Author(s):  
Kuno Hottenrott ◽  
Erik Hass ◽  
Manon Kraus ◽  
Georg Neumann ◽  
Martin Steiner ◽  
...  

We investigated whether an athlete’s self-chosen nutrition strategy (A), compared with a scientifically determined one (S), led to an improved endurance performance in a laboratory time trial after an endurance exercise. S consisted of about 1000 mL·h–1 fluid, in portions of 250 mL every 15 min, 0.5 g sodium·L–1, 60 g glucose·h–1, 30 g fructose·h–1, and 5 mg caffeine·kg body mass–1. Eighteen endurance-trained cyclists (16 male; 2 female) were tested using a randomized crossover-design at intervals of 2 weeks, following either A or S. After a warm-up, a maximal oxygen uptake test was performed. Following a 30-min break, a 2.5-h endurance exercise on a bicycle ergometer was carried out at 70% maximal oxygen uptake. After 5 min of rest, a time trial of 64.37 km (40 miles) was completed. The ingested nutrition was recorded every 15 min. In S, the athletes completed the time trial faster (128 vs. 136 min; p ≤ 0.001) and with a significantly higher power output (212 vs. 184 W; p ≤ 0.001). The intake of fluid, energy (carbohydrate-, mono-, and disaccharide), and sodium was significantly higher in S compared with A (p ≤ 0.001) during the endurance exercise. In the time trial, only sodium intake was significantly higher in S (p ≤ 0.001). We concluded that a time trial performance after a 2.5-h endurance exercise in a laboratory setting was significantly improved following a scientific nutrition strategy.


2008 ◽  
Vol 3 (2) ◽  
pp. 157-163 ◽  
Author(s):  
L.R. McNaughton ◽  
R.J. Lovell ◽  
J. Siegler ◽  
A.W. Midgley ◽  
L. Moore ◽  
...  

Purpose:The purpose of this work was to determine the effects of caffeine on high intensity time trial (TT) cycling performance in well-trained subjects.Subjects:Six male cyclists with the following physical characteristics (mean ± SD) age 30.7 ± 12, height 179.3 ± 7.5 cm, mass 70.0 ± 7.5 kg, VO2max 65.0 ± 6.3 mL·kg−1·min−1 undertook three 1-h TT performances, control (C), placebo (P) and caffeine (CAF), on a Velotron cycle ergometer conducted in a double-blind, random fashion. Subjects rested for 60 min and were then given CAF or P in a dose of 6 mg·kg−1 body mass and then commenced exercise after another 60 min of rest. Before ingestion, 60 min postingestion, and at the end of the TT, finger-prick blood samples were analyzed for lactate.Results:The cyclists rode significantly further in the CAF trial (28.0 ± 1.3 km) than they did in the C (26.3 ± 1.5 km, P < .01) or P (26.4 ± 1.5 km, P < .02) trials. No differences were seen in heart rate data throughout the TT (P > .05). Blood lactate levels were significantly higher at the end of the trials than either at rest or postingestion (P < .0001), but there were no differences between the three trial groups.Conclusion:On the basis of the data, we concluded that performance was improved with the use of a caffeine supplement.


2020 ◽  
Vol 45 (5) ◽  
pp. 513-519 ◽  
Author(s):  
Cheong Hwa Ooi ◽  
Siew Kit Ng ◽  
Eshaifol Azam Omar

There is emerging evidence that hydrogen-rich water (H2-water) has beneficial effects on the physiological responses to exercise. However, few studies investigate its ergogenic potential. This randomized controlled trial examined the effects of H2-water ingestion on physiological responses and exercise performance during incremental treadmill running. In a double-blind crossover design, 14 endurance-trained male runners (age, 34 ± 4 years; body mass, 63.1 ± 7.2 kg; height, 1.72 ± 0.05 m) were randomly assigned to ingest 2 doses of 290-mL H2-water or placebo on each occasion. The first bolus was given before six 4-min submaximal running bouts, and the second bolus was consumed before the maximal incremental running test. Expired gas, heart rate (HR), and ratings of perceived exertion (RPE) were recorded; blood samples were collected at the end of each submaximal stage and post maximal running test. Cardiorespiratory responses, RPE, and blood gas indices were not significantly different at each submaximal running intensity (range: 34%–91% maximal oxygen uptake) between H2-water and placebo trials. No statistical difference was observed in running time to exhaustion (618 ± 126 vs. 619 ± 113 s), maximal oxygen uptake (56.9 ± 4.4 vs. 57.1 ± 4.7 mL·kg−1·min−1), maximal HR (184 ± 7 vs. 184 ± 7 beat·min−1), and RPE (19 ± 1 vs. 19 ± 1) in the runners between the trials. The results suggest that the ingestion of 290 mL of H2-water before submaximal treadmill running and an additional dose before the subsequent incremental running to exhaustion were not sufficiently ergogenic in endurance-trained athletes. Novelty Acute ingestion of H2-water does not seem to be ergogenic for endurance performance. A small dose of H2-water does not modulate buffering capacity during intense endurance exercise in athletes.


2006 ◽  
Vol 16 (4) ◽  
pp. 405-419 ◽  
Author(s):  
Holden S-H. MacRae ◽  
Kari M. Mefferd

We investigated whether 6 wk of antioxidant supplementation (AS) would enhance 30 km time trial (TT) cycling performance. Eleven elite male cyclists completed a randomized, double-blind, cross-over study to test the effects of twice daily AS containing essential vitamins plus quercetin (FRS), and AS minus quercetin (FRS-Q) versus a baseline TT (B). MANOVA analysis showed that time to complete the 30 km TT was improved by 3.1% on FRS compared to B (P ≤ 0.01), and by 2% over the last 5 km (P ≤ 0.05). Absolute and relative (%HRmax) heart rates and percent VO2max were not different between trials, but average and relative power (% peak power) was higher on FRS (P ≤ 0.01). Rates of carbohydrate and fat oxidation were not different between trials. Thus, FRS supplementation significantly improved high-intensity cycling TT performance through enhancement of power output. Further study is needed to determine the potential mechanism(s) of the antioxidant efficacy.


2019 ◽  
Vol 14 (1) ◽  
pp. 105-112 ◽  
Author(s):  
Andrew J. Carnes ◽  
Sara E. Mahoney

Purpose: This study longitudinally compared changes in running performance (5-km time trial) and fitness (maximal oxygen uptake [VO2max] and body composition [BC]) between polarized training and CrossFit Endurance (CFE) in recreational runners. Methods: Participants (N = 21) completed 12 wk of CFE or polarized endurance training (POL). Both groups trained 5 d·wk−1. POL ran 5 d·wk−1, whereas CFE ran 3 d·wk−1 and performed CrossFit 3 d·wk−1 (run + CrossFit 1 d·wk−1). Intensity was classified as low, moderate, or high (zone 1, 2, or 3) according to ventilatory thresholds. POL was prescribed greater volume (295 [67] min·wk−1), distributed as 85%/5%/10% in Z1/Z2/Z3. CFE emphasized a lower volume (110 [18] min·wk−1) distribution of 48%/8%/44%. Results: POL ran 283 (75.9) min·wk−1 and 47.3 (11.6) km·wk−1, both exceeding the 117 (32.2) min·wk−1 and 19.3 (7.17) km·wk−1 in CFE (P < .001). The POL distribution (74%/11%/15%) had greater total and percentage Z1 (P < .001) than CFE (46%/15%/39%), which featured higher percentage Z3 (P < .001). Time trial improved −93.8 (40.4) s (−6.21% [2.16%]) in POL (P < .001) and −84.2 (65.7) s (−5.49% [3.56%]) in CFE (P = .001). BC improved by −2.45% (2.59%) fat in POL (P = .02) and −2.62% (2.53%) in CFE (P = .04). The magnitude of improvement was not different between groups for time trial (P = .79) or BC (P = .88). Both groups increased VO2max (P ≤ .01), but with larger magnitude (P = .04, d = 0.85) in POL (4.3 [3.6] mL·kg·min−1) than CFE (1.78 [1.9] mL·kg·min−1). Conclusions: Recreational runners achieved similar improvement in 5-km performance and BC through polarized training or CFE, but POL yielded a greater increase in VO2max. Extrapolation to longer distances requires additional research.


Sports ◽  
2019 ◽  
Vol 7 (10) ◽  
pp. 217 ◽  
Author(s):  
Arne Sørensen ◽  
Tore Kristian Aune ◽  
Vegar Rangul ◽  
Terje Dalen

Cycling is a popular sport, and evaluation of the validity of tests to predict performance in competitions is important for athletes and coaches. Similarity between performance in sprints in mass-start bike races and in the laboratory is found, but, to our knowledge, no studies have investigated the relationship between laboratory measurements of maximal oxygen uptake (VO2max) and functional threshold power (FTP) with performance in official mass-start competitions. The purpose of this study was to evaluate the validity of a 20 min FTP test and VO2max as predictors for performance in an official mountain bike competition. Eleven moderately trained male cyclists at a local level participated in this study (age: 43 ± 5.1 years; height: 183.4 ± 5.4 m; weight: 84.4 ± 8.7 kg; body mass index: 25.1 ± 2.1). All subjects performed a 20 min FTP test in the laboratory to measure the mean power. In addition, the subjects completed an incremental test to exhaustion to determine VO2max. These two laboratory tests were analyzed together with the results from a 47 km mass-start mountain bike race, with a total elevation of 851 m. A significant relationship was found between the mean relative power (W/kg) for the 20 min FTP test and performance time in the race (r = −0.74, P < 0.01). No significant correlation was found between VO2max and cycling performance for these subjects (r = −0.37). These findings indicate that a 20 min FTP test is a more valid test for prediction of performance in mass-start bike races than a VO2max test for moderately trained cyclists.


2019 ◽  
Vol 127 (6) ◽  
pp. 1651-1659 ◽  
Author(s):  
Amadeo F. Salvador ◽  
Colleen F. McKenna ◽  
Rafael A. Alamilla ◽  
Ryan M. T. Cloud ◽  
Alexander R. Keeble ◽  
...  

Carbohydrate (CHO) ingestion is an established strategy to improve endurance performance. Race fuels should not only sustain performance but also be readily digested and absorbed. Potatoes are a whole-food-based option that fulfills these criteria, yet their impact on performance remains unexamined. We investigated the effects of potato purée ingestion during prolonged cycling on subsequent performance vs. commercial CHO gel or a water-only condition. Twelve cyclists (70.7 ± 7.7 kg, 173 ± 8 cm, 31 ± 9 yr, 22 ± 5.1% body fat; means ± SD) with average peak oxygen consumption (V̇o2peak) of 60.7 ± 9.0 mL·kg−1·min−1 performed a 2-h cycling challenge (60–85% V̇o2peak) followed by a time trial (TT; 6 kJ/kg body mass) while consuming potato, gel, or water in a randomized-crossover design. The race fuels were administered with [U-13C6]glucose for an indirect estimate of gastric emptying rate. Blood samples were collected throughout the trials. Blood glucose concentrations were higher ( P < 0.001) in potato and gel conditions compared with water condition. Blood lactate concentrations were higher ( P = 0.001) after the TT completion in both CHO conditions compared with water condition. TT performance was improved ( P = 0.032) in both potato (33.0 ± 4.5 min) and gel (33.0 ± 4.2 min) conditions compared with water condition (39.5 ± 7.9 min). Moreover, no difference was observed in TT performance between CHO conditions ( P = 1.00). In conclusion, potato and gel ingestion equally sustained blood glucose concentrations and TT performance. Our results support the effective use of potatoes to support race performance for trained cyclists. NEW & NOTEWORTHY The ingestion of concentrated carbohydrate gels during prolonged exercise has been shown to promote carbohydrate availability and improve exercise performance. Our study aim was to expand and diversify race fueling menus for athletes by providing an evidence-based whole-food alternative to the routine ingestion of gels during training and competition. Our work shows that russet potato ingestion during prolonged cycling is as effective as carbohydrate gels to support exercise performance in trained athletes.


2016 ◽  
Vol 41 (8) ◽  
pp. 864-871 ◽  
Author(s):  
Phillip M. Bellinger ◽  
Clare L. Minahan

The present study investigated the effects of β-alanine supplementation on the resultant blood acidosis, lactate accumulation, and energy provision during supramaximal-intensity cycling, as well as the aerobic and anaerobic contribution to power output during a 4000-m cycling time trial (TT). Seventeen trained cyclists (maximal oxygen uptake = 4.47 ± 0.55 L·min−1) were administered 6.4 g of β-alanine (n = 9) or placebo (n = 8) daily for 4 weeks. Participants performed a supramaximal cycling test to exhaustion (equivalent to 120% maximal oxygen uptake) before (PreExh) and after (PostExh) the 4-week supplementation period, as well as an additional postsupplementation supramaximal cycling test identical in duration and power output to PreExh (PostMatch). Anaerobic capacity was quantified and blood pH, lactate, and bicarbonate concentrations were measured pre-, immediately post-, and 5 min postexercise. Subjects also performed a 4000-m cycling TT before and after supplementation while the aerobic and anaerobic contributions to power output were quantified. β-Alanine supplementation increased time to exhaustion (+12.8 ± 8.2 s; P = 0.041) and anaerobic capacity (+1.1 ± 0.7 kJ; P = 0.048) in PostExh compared with PreExh. Performance time in the 4000-m TT was reduced following β-alanine supplementation (−6.3 ± 4.6 s; P = 0.034) and the mean anaerobic power output was likely to be greater (+6.2 ± 4.5 W; P = 0.035). β-Alanine supplementation increased time to exhaustion concomitant with an augmented anaerobic capacity during supramaximal intensity cycling, which was also mirrored by a meaningful increase in the anaerobic contribution to power output during a 4000-m cycling TT, resulting in an enhanced overall performance.


2010 ◽  
Vol 20 (2) ◽  
pp. 122-131 ◽  
Author(s):  
Darren Triplett ◽  
J. Andrew Doyle ◽  
Jeffrey C. Rupp ◽  
Dan Benardot

A number of recent research studies have demonstrated that providing glucose and fructose together in a beverage consumed during exercise results in significantly higher oxidation rates of exogenous carbohydrate (CHO) than consuming glucose alone. However, there is insufficient evidence to determine whether the increased exogenous CHO oxidation improves endurance performance. The purpose of this study was to determine whether consuming a beverage containing glucose and fructose (GF) would result in improved cycling performance compared with an isocaloric glucose-only beverage (G). Nine male competitive cyclists (32.6 ± 5.8 years, peak oxygen uptake 61.5 ± 7.9 ml · kg-1 · min-1) completed a familiarization trial and then 2 simulated 100-km cycling time trials on an electronically braked Lode cycle ergometer separated by 5–7 d. During the randomly ordered experimental trials, participants received 36 g of CHO of either G or GF in 250 ml of water every 15 min. All 9 participants completed the 100-km time trial significantly faster when they received the GF beverage than with G (204.0 ± 23.7 vs. 220.6 ± 36.6 min; p = .023). There was no difference at any time point between trials for blood glucose or for blood lactate. Total CHO oxidation increased significantly from rest during exercise but was not statistically significant between the GF and G trials, although there was a trend for CHO oxidation to be higher with GF in the latter stages of the time trial. Consumption of a CHO beverage containing glucose and fructose results in improved 100-km cycling performance compared with an isocaloric glucose-only beverage.


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