Teaching ventilation/perfusion relationships in the lung

2008 ◽  
Vol 32 (3) ◽  
pp. 192-195 ◽  
Author(s):  
Robb W. Glenny

This brief review is meant to serve as a refresher for faculty teaching respiratory physiology to medical students. The concepts of ventilation and perfusion matching are some of the most challenging ideas to learn and teach. Some strategies to consider in teaching these concepts are, first, to build from simple to more complex by starting with a single lung unit and then adding additional units representing shunting, mismatch, and deadspace. Second, use simplified analogies, such as a bathtub, to help students conceptualize new ideas. Third, introduce the concept of alveolar to arterial O2 differences and the mechanisms for increasing differences as additional lung units are added. Fourth, use the consistent thread of causes of hypoxemia through the lecture to maintain continuity and provide clinical relevance. Finally, use clinically relevant examples at each step and solidify new concepts by discussing differential diagnoses at the end of the lecture(s).

2018 ◽  
Vol 42 (4) ◽  
pp. 655-660
Author(s):  
Marcelo Alcantara Holanda ◽  
Nathalia Parente de Sousa ◽  
Luana Torres Melo ◽  
Liégina Silveira Marinho ◽  
Helder Veras Ribeiro-Filho ◽  
...  

Undergraduate biomedical students often have difficulties in understanding basic concepts of respiratory physiology, particularly respiratory mechanics. In this study, we report the use of electrical impedance tomography (EIT) to improve and consolidate the knowledge about physiological aspects of normal regional distribution of ventilation in humans. Initially, we assessed the previous knowledge of a group of medical students ( n = 39) about regional differences in lung ventilation. Thereafter, we recorded the regional distribution of ventilation through surface electrodes on a healthy volunteer adopting four different decubitus positions: supine, prone, and right and left lateral. The recordings clearly showed greater pulmonary ventilation in the dependent lung, mainly in the lateral decubitus. Considering the differences in pulmonary ventilation between right and left lateral decubitus, only 33% of students were able to notice it correctly beforehand. This percentage increased to 84 and 100%, respectively ( P < 0.01), after the results of the ventilation measurements obtained with EIT were examined and discussed. A self-assessment questionnaire showed that students considered the practical activity as an important tool to assist in the understanding of the basic concepts of respiratory mechanics. Experimental demonstration of the physiological variations of regional lung ventilation in volunteers by using EIT is feasible, effective, and stimulating for undergraduate medical students. Therefore, this practical activity may help faculty and students to overcome the challenges in the field of respiratory physiology learning.


2021 ◽  
Vol 71 (1) ◽  
pp. 351-56
Author(s):  
Naureen Waseem ◽  
Aaqiba Rasheed ◽  
Maria Gill ◽  
Ayesha Asad ◽  
Muhammad Omar Shamim ◽  
...  

Objective of Study: The objective of this study is to have an insight on student’s attitudes regarding histology’s clinical relevance in public and private sector medical college. Methodology: A cross sectional survey for attitude analysis towards histology’s clinical importance was carried out among 200 third year medical students from private and public sector medical college. Thurdstone and Chave attitude analysis questionnaire was employed to find the attitude score. Results: Students of both public and private sector medical college show scepticism towards the clinical importance of histology. There was no marked difference in the attitudes of students of public and private sector medical college. Most data remained on the borderline of the attitude scale employed. Conclusion: This study provided useful information for the teachers that students do not appreciate the clinical importance of histology much. Teachers need to devise strategies and to work on the students helping them comprehend the importance of histology.


Author(s):  
Robert Laureno

This chapter on “Selected Concepts” examines the evolution of neurological concepts during the modern era. Examples presented include the concepts of transient ischemic attack, disconnection syndrome, thoracic outlet syndrome, and Wilbrand’s knee. Over the past half century, neurology has witnessed great technological advances. Newer scientific methods, such as MRI scanning, have led to new knowledge that has necessitated changes in neurologic concepts. During recent decades, new concepts have emerged. Infectious proteins, antibody-mediated brain disease, channelopathies, and the glymphatic system are relatively new ideas, and we cannot foresee how our understanding of these concepts will be advanced or modified in the coming decades.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Fares Gouzi ◽  
Christophe Hédon ◽  
Léo Blervaque ◽  
Emilie Passerieux ◽  
Nils Kuster ◽  
...  

Abstract Background Over-testing of patients is a significant problem in clinical medicine that can be tackled by education. Clinical reasoning learning (CRL) is a potentially relevant method for teaching test ordering and interpretation. The feasibility might be improved by using an interactive whiteboard (IWB) during the CRL sessions to enhance student perceptions and behaviours around diagnostic tests. Overall, IWB/CRL could improve their skills. Methods Third-year undergraduate medical students enrolled in a vertically integrated curriculum were randomized into two groups before clinical placement in either a respiratory disease or respiratory physiology unit: IWB-based CRL plus clinical mentoring (IWB/CRL + CM: n = 40) or clinical mentoring only (CM-only: n = 40). Feasibility and learning outcomes were assessed. In addition, feedback via questionnaire of the IWB students and their classmates (n = 233) was compared. Results Analyses of the IWB/CRL sessions (n = 40, 27 paperboards) revealed that they met validated learning objectives. Students perceived IWB as useful and easy to use. After the IWB/CRL + CM sessions, students mentioned more hypothesis-based indications in a test ordering file (p <  0.001) and looked for more nonclinical signs directly on raw data tests (p <  0.01) compared with students in the CM-only group. Last, among students who attended pre- and post-assessments (n = 23), the number of diagnostic tests ordered did not change in the IWB/CRL + CM group (+ 7%; p = N.S), whereas it increased among CM-only students (+ 30%; p <  0.001). Test interpretability increased significantly in the IWB/CRL + CM group (from 4.7 to 37.2%; p <  0.01) but not significantly in the CM-only group (from 2.4 to 9.8%; p = 0.36). Conclusions Integrating IWB into CRL sessions is feasible to teach test ordering and interpretation to undergraduate students. Moreover, student feedback and prospective assessment suggested a positive impact of IWB/CRL sessions on students’ learning.


2015 ◽  
Vol 81 (1) ◽  
pp. 96-100 ◽  
Author(s):  
Ean R. Saberski ◽  
Sean B. Orenstein ◽  
Dale Matheson ◽  
Yuri W. Novitsky

Medical curricula are continually evolving and increasing clinical relevance. Gross anatomy educators have tested innovations to improve the clinical potency of anatomic dissection and found that clinical correlations are an effective method to accomplish this goal. Recently, surgical educators defined a role for laparoscopy in teaching anatomy. We aimed to expand this role by using surgical educators to create clinical correlates between gross anatomy and clinical surgery. We held supplements to traditional anatomy open dissection for medical students, including viewing prerecorded operative footage and live laparoscopic dissection performed on cadavers. The main outcome measures were assessed through pre- and postsession surveys. Greater than 75 per cent of students found the demonstrations highly valuable, and students perceived a significant increase in their understanding of abdominopelvic anatomy ( P < 0.01). Additionally, 62 per cent of students with previous interest in surgery and 10 per cent of students without previous interest in surgery reported increased interest in pursuing surgical careers. Our demonstrations advance the use of minimally invasive surgical technology to teach gross anatomy. Live laparoscopic demonstrations augment traditional anatomic instruction by reinforcing the clinical relevance of abdominopelvic anatomy. Additionally, laparoscopic demonstrations generate interest in surgery that would otherwise be absent in the preclinical years.


2020 ◽  
Vol 9 (5) ◽  
pp. 676-682
Author(s):  
Phumzile Sikakana ◽  
Ruth A Roberts

Abstract Here we look at popular trends and concepts in toxicology over the decade 2009–2019. The top 10 concepts included methodological approaches such as zebrafish and genomics as well as broader concepts such as personalized medicine and adverse outcome pathways. The total number and rank order for each of the top 10 were tracked year by year via PubMed with &gt;9500 papers contributing to the analysis. The data revealed a slow upward trend in the number of papers across all the concepts from 260 in 2009 to &gt;1700 in 2019. Zebrafish, genomics and personalized medicine remained in the top four slots since 2009 with zebrafish dominating the rankings over the entire decade. Genomics was a strong second until 2013 when it was displaced first by the microbiome in 2014 and secondly by personalized medicine in 2015. Other notable trends were the ascendancy of the microbiome and adverse outcome pathways and the descendancy of hormesis and the 3Rs (replacement, reduction and refinement of animals in testing). The observation that the top four slots have been static over the past 4 years suggests that new ideas are introduced and increase in popularity until they find their place in scientific culture. This may suggest that relatively new concepts such as artificial intelligence and microphysiological systems have yet to find their steady state in the rankings. Similarly, as a relatively new player in toxicology, the full impact of the human microbiome on drug efficacy and safety remains to be seen.


2012 ◽  
Vol 21 (01) ◽  
pp. 1250002
Author(s):  
FRANCISCO GÁMIZ ◽  
NOEL RODRIGUEZ ◽  
SORIN CRISTOLOVEANU

With 30nm-class memory cells in production and 20nm-class (20-29nm feature-size) memory targeted for next year, the standard 1-Transistor + 1-Capacitor (1T+1C) DRAM industry is making prominent efforts to improve the scalability of the cell capacitor while maintaining the minimum capacitance requirements for state discrimination, immune to noise (C~25fF/cell). To achieve the capacitance requirement, the DRAM cell has evolved from its initial planar implementation to complex three-dimensional structures. The increment in complexity and the large difference in size between the transistor and capacitor of each cell have motivated the search for Floating-Body Single-Transistor DRAM (1T-DRAM). The underlying idea behind 1T-DRAMs is the development of single-device memory cells with a pronounced hysteresis effect and fast operation. This chapter is focused on the floating-body effect as a primary source of hysteresis. We present new concepts able to deal with the basic limitations of 1T-DRAM while maintaining its simplicity. The floating-body 1T-DRAMs can be reconciled with the aggressive scaling constrains by considering new ideas which make possible the coexistence of electron and holes in the same ultrathin transistor. The best approach is to isolate each type of carrier in an specific potential well which is not created specifically by the bias conditions (unlike standard 1T-DRAMs) but by the physical structure of the device.


Author(s):  
P. A. Simionescu ◽  
Mehrube Mehrubeoglu

The use of information visualization in engineering analysis and design has increased exponentially, making it indispensable in science and engineering education. In this paper, several new concepts on graphical representation of two-dimensional data are presented, and their implementation in a computer program called D_2D detailed. Application examples include mechanism kinematics, vibrations, and optimizations. New ideas on plotting inequalities of two variables, damping ratio evaluation of single degree-of-freedom vibratory systems, and time ratio calculation of crank-driven mechanisms are presented in paper.


2005 ◽  
Vol 69 (6) ◽  
pp. 663-670 ◽  
Author(s):  
Terry D. Stratton ◽  
Donald B. Witzke ◽  
Mary Jane Freund ◽  
Martha T. Wilson ◽  
Robert J. Jacob

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