A Highly Sensitive and Signal-On Electrochemical Aptasensor Based on Restriction Endonuclease Induced Background Elimination

2016 ◽  
Vol 163 (8) ◽  
pp. B411-B416
Author(s):  
Songbai Zhang ◽  
Xia Hu ◽  
Hongen Geng ◽  
Meixin Huang ◽  
Yanqing Qiu ◽  
...  
2016 ◽  
Vol 40 (11) ◽  
pp. 9711-9718 ◽  
Author(s):  
Junling Yin ◽  
Wenjuan Guo ◽  
Xiaoli Qin ◽  
Meishan Pei ◽  
Luyan Wang ◽  
...  

A novel aptasensor based on PCNRs and MWCNTs–CuO–AuNPs as the nanomatrix was constructed for the highly sensitive detection of streptomycin.


2016 ◽  
Vol 8 (39) ◽  
pp. 7247-7253 ◽  
Author(s):  
Mohammad Hossein Mashhadizadeh ◽  
Niloofar Naseri ◽  
Masoud A. Mehrgardi

In this work, a highly sensitive aptasensor for digoxin determination in biological samples has been introduced.


The Analyst ◽  
2020 ◽  
Vol 145 (22) ◽  
pp. 7340-7348
Author(s):  
Huasong Bai ◽  
Shengjun Bu ◽  
Wensen Liu ◽  
Chengyu Wang ◽  
Zhongyi Li ◽  
...  

We developed an electrochemical aptasensor based on cocoon-like DNA nanostructures as signal tags for highly sensitive and selective detection of Escherichia coli O157:H7.


2009 ◽  
Vol 54 (26) ◽  
pp. 6207-6211 ◽  
Author(s):  
Zhongyuan Liu ◽  
Ruo Yuan ◽  
Yaqin Chai ◽  
Ying Zhuo ◽  
Chenglin Hong ◽  
...  

2016 ◽  
Vol 94 (5) ◽  
pp. 509-514 ◽  
Author(s):  
Yunqing Liu ◽  
Xia Zhang ◽  
Junshuai Yang ◽  
Erhu Xiong ◽  
Xiaohua Zhang ◽  
...  

A new ratiometric electrochemical aptasensor has been developed for highly sensitive and selective detection of bisphenol A (BPA). The double-stranded DNA (dsDNA), consisting of the BPA aptamer (DNA1) and methylene blue (MB)-labeled complementary DNA (cDNA), was immobilized on a gold nanoparticle (AuNP) modified glassy carbon (GC) electrode. In the presence of BPA, the specific BPA–aptamer interaction drove the release of the MB-labeled cDNA from the electrode surface. As a result, the oxidation peak current of MB (IMB) decreased and that of BPA (IBPA) increased. The peak current ratio (IBPA/IMB) of BPA and MB was linear with the concentration of BPA in the range from 1 to 100 pmol/L with a detection limit of 0.6 pmol/L. The detection limit is much lower than that obtained by most of the reported electrochemical methods. On the other hand, the developed aptasensor possesses good selectivity, reproducibility, and stability, and the related sensing structure is very simple, showing promising practical applications in BPA assays.


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