scholarly journals Pediatric Hepatoblastoma, Hepatocellular Carcinoma, and Other Hepatic Neoplasms: Consensus Imaging Recommendations from American College of Radiology Pediatric Liver Reporting and Data System (LI-RADS) Working Group

Radiology ◽  
2020 ◽  
Vol 296 (3) ◽  
pp. 493-497 ◽  
Author(s):  
Gary R. Schooler ◽  
Judy H. Squires ◽  
Adina Alazraki ◽  
Govind B. Chavhan ◽  
Victoria Chernyak ◽  
...  
2020 ◽  
Vol 30 (1) ◽  
pp. 261-271 ◽  
Author(s):  
Nieun Seo ◽  
Myoung Soo Kim ◽  
Mi-Suk Park ◽  
Jin-Young Choi ◽  
Richard K. G. Do ◽  
...  

Author(s):  
Hang Zhou ◽  
Chao Zhang ◽  
Linyao Du ◽  
Jiapeng Jiang ◽  
Qing Zhao ◽  
...  

Abstract Objectives To determine the diagnostic performance and inter-reader agreement of the contrast-enhanced ultrasound liver imaging reporting and data system (CEUS-LI-RADS) for diagnosing hepatocellular carcinoma (HCC) in high-risk patients. Methods In this prospective study, CEUS-LI-RADS categories (LR-5 for predicting HCC) were assigned by six blinded readers and compared to the definitive HCC diagnosis in patients with liver cirrhosis per the 2017 China Liver Cancer Guidelines (CLCG). CEUS features were recorded in 96 patients with 96 histology-proven lesions. The diagnostic performance of LR-5 was described by the sensitivity, specificity and accuracy. Multi-reader agreement was assessed by using intraclass correlation coefficients (ICC). Results In cirrhotic patients, the specificity of LR-5 (range: 92.7–100.0 %) was statistically higher than that of CLCG for each reader (range: 28.6–64.3 %). However, the sensitivity (range: 38.6–63.6 %) and accuracy (range: 53.4–70.7 %) were statistically lower in CEUS-LIRADS than in CLCG (sensitivity range: 88.6–100.0 %; accuracy range: 77.6–86.2 %). Only fair to moderate inter-reader agreement was achieved for the CEUS-LI-RADS category (ICC = 0.595) and washout appearance (ICC range: 0.338 to 0.555). Neither nodule-in-nodule nor mosaic architecture was observed more often in HCC (all P > 0.05), with poor inter-reader consistency for both (both ICC < 0.20). Conclusion CEUS-LI-RADS category 5 has a high specificity but a low accuracy for identifying HCC in high-risk patients. Inter-reader agreement is not satisfactory concerning CEUS-LIRADS category and washout appearance. Moreover, the clinical value of ancillary features favoring HCC is quite limited.


2019 ◽  
Vol 25 (10) ◽  
pp. 1488-1502 ◽  
Author(s):  
Victoria Chernyak ◽  
Milana Flusberg ◽  
Jesse Berman ◽  
Kate C. Fruitman ◽  
Mariya Kobi ◽  
...  

2020 ◽  
pp. 000313482096006
Author(s):  
Eliza W. Beal ◽  
Kirstin Foley ◽  
Ken Washburn ◽  
Allan Tsung

A 59-year-old woman presented with abdominal bloating, elevated alkaline phosphatase and transaminases, and computed tomography abdomen/pelvis demonstrating large right-sided hepatic masses. A percutaneous fine needle aspiration demonstrated hepatocellular neoplasm concerning for hepatocellular carcinoma. Preoperative imaging demonstrated possible porto-caval shunt. She underwent uneventful right hepatic lobectomy with confirmation of porto-systemic shunt. Congenital porto-systemic shunt, or Abernethy malformation, is rare and is associated with congenital cardiac and gastrointestinal abnormalities. Additionally, congenital porto-systemic shunt is associated with increased risk of hepatic neoplasms including hepatocellular carcinoma. Recommended surveillance for these patients is not well defined.


2020 ◽  
Vol 75 (6) ◽  
pp. 478.e25-478.e35 ◽  
Author(s):  
A.-H. Ren ◽  
J.-B. Du ◽  
D.-W. Yang ◽  
P.-F. Zhao ◽  
Z.-C. Wang ◽  
...  

2020 ◽  
Vol 17 (10) ◽  
pp. 1199-1206 ◽  
Author(s):  
Sunyoung Lee ◽  
Yeun-Yoon Kim ◽  
Jaeseung Shin ◽  
Shin Hye Hwang ◽  
Yun Ho Roh ◽  
...  

2017 ◽  
Vol 43 (1) ◽  
pp. 41-55 ◽  
Author(s):  
Tara A. Morgan ◽  
◽  
Katherine E. Maturen ◽  
Nirvikar Dahiya ◽  
Maryellen R. M. Sun ◽  
...  

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