Differential effects of pharmacologically generated reactive oxygen species upon functional activity of epididymal mouse spermatozoa

1997 ◽  
Vol 75 (3) ◽  
pp. 173-178 ◽  
Author(s):  
G Baiardi ◽  
R D Ruiz ◽  
M Fiol de Cuneo ◽  
A A Ponce ◽  
J L Lacuara ◽  
...  
2012 ◽  
Vol 28 (4) ◽  
pp. 239-253 ◽  
Author(s):  
Vincent Rincheval ◽  
Marie Bergeaud ◽  
Lise Mathieu ◽  
Jacqueline Leroy ◽  
Arnaud Guillaume ◽  
...  

2020 ◽  
Vol 204 (8) ◽  
pp. 2133-2142 ◽  
Author(s):  
Karin Margaretha Gilljam ◽  
Kristine Lillebø Holm ◽  
Muhammad Zahoor ◽  
Federica Grazia Centonze ◽  
Hesso Farhan ◽  
...  

2015 ◽  
Vol 61 (1) ◽  
pp. 57-69 ◽  
Author(s):  
E.E. Dubinina ◽  
L.V. Schedrina ◽  
N.G. Neznanov ◽  
N.M. Zalutskaya ◽  
D.V. Zakharchenko

The paper summarizes literature data on the importance of oxidative stress as one of the pathogenetic mechanisms in Alzheimer's disease. The paper describes the main specific and nonspecific ways of reactive oxygen species generation in the course of the disease development. The effect of reactive oxygen species generated by the functional activity of cells, i.e. apoptosis and mitotic cycle, is shown. The role of the regulatory system of nodal cells is performed by phosphorylation/dephosphorylation process which is associated with intense phosphorylation of tau protein and mitosis-specific proteins. In Alzheimer's disease, the regulating function of peptidyl-prolyl isomerases in particular of Pin1 associated with maintaining a balanced state of phosphorylation/dephosphorylation processes is disturbed. Taking into consideration the multifactorial impairment of the cell cycle control, this process should be considered from the standpoint of the general state of metabolic processes, and oxidative stress has one of the key positions in aging.


2009 ◽  
Vol 1787 (5) ◽  
pp. 384-392 ◽  
Author(s):  
Romana Fato ◽  
Christian Bergamini ◽  
Marco Bortolus ◽  
Anna Lisa Maniero ◽  
Serena Leoni ◽  
...  

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