EFFECT OF FORCED RESTRAINT ON HEART PHOSPHOLIPIDS

1967 ◽  
Vol 45 (3) ◽  
pp. 407-413 ◽  
Author(s):  
P. Prioreschi ◽  
E. Peterman
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Phosphatidyl Ethanolamine ◽  
Resting Period

The cardiac level of phospholipids and their fatty acid composition were measured in the rat after different periods of forced restraint and different periods of rest. After 4 minutes of forced immobilization the level of heart cardiolipin decreased by about 75%. When the animal was immobilized for 24 hours the concentration of cardiolipin in the heart returned to normal after less than 96 hours of rest. The concentration of sphingomyelin was also decreased by forced restraint whereas phosphatidyl ethanolamine decreased only in the resting period after immobilization. The significance of these findings in the pathogenesis of experimental cardiac necroses is discussed.

THE TRANSPORT OF PHOSPHOLIPIDS FROM THE YOLK TO THE YOLK-SAC MEMBRANE DURING THE DEVELOPMENT OF THE CHICK EMBRYO

1967 ◽  
Vol 45 (7) ◽  
pp. 1125-1133 ◽  
Author(s):  
R. C. Noble ◽  
J. H. Moore
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Chick Embryo ◽  
Stearic Acid ◽  
Acid Composition ◽  
Phosphatidyl Choline ◽  
Phosphatidyl Ethanolamine ◽  
Yolk Sac ◽  
Membrane Phospholipids ◽  
Lysophosphatidyl Choline

A study was made of the concentrations and fatty acid compositions of the various phospholipid fractions in the yolks and yolk-sac membranes at different stages in the development of the chick embryo. Phosphatidyl choline was the major component of both the yolk and membrane phospholipids. The composition of the yolk phospholipids was broadly similar to that of the membrane phospholipids. In both the yolk and membrane phospholipids, the proportions of phosphatidyl choline and phosphatidyl ethanolamine tended to decrease, whereas the proportions of phosphatidyl serine, sphingomyelin, and lysophosphatidyl choline tended to increase as incubation proceeded. The fatty acid composition of the yolk phosphatidyl choline did not change during incubation, but there was a progressive decrease in the palmitic acid: stearic acid ratio in the membrane phosphatidyl choline. The changes in the fatty acid composition of the yolk phosphatidyl ethanolamine indicated that there was a preferential absorption from the yolk of phosphatidyl ethanolamine with stearic acid in the α position and arachidonic or docosahexaenoic acids in the β position. The lysophosphatidyl choline in the yolk and membrane evidently consisted of mixtures of the 1-acyl and 2-acyl isomers. There was no evidence that extensive breakdown and resynthesis of phospholipids occurred during the transport of lipids from the yolk to the yolk-sac membrane.

Preferential inhibition of phosphatidyl ethanolamine synthesis in E. coli by alcohols

1977 ◽  
Vol 23 (6) ◽  
pp. 779-789 ◽  
Author(s):  
L. O. Ingram
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Phosphatidyl Ethanolamine ◽  
Phosphatidyl Serine ◽  
Total Fatty Acid Composition ◽  
E Coli ◽  
Phospholipid Classes ◽  
Induced Changes ◽  
Chain Lengths

Growth of E. coli in the presence of alcohols of chain lengths 1 through 8 results in an increase in the relative abundance of phosphatidyl glycerol. This results primarily from the preferential inhibition of phosphatidyl ethanolamine synthesis. This inhibition appears to be unrelated to membrane fluidity or to changes in fatty acid composition caused by alcohols. Alcohol-induced changes in total fatty acid composition are reflected in all phospholipid classes. Phosphatidyl serine synthetase is proposed as the most likely site for the effects of alcohols on phospholipid synthesis.

Effect of Isoprenaline on Salivary Gland Lipids of Rats Fed a Choline-Deficient Diet

1978 ◽  
Vol 57 (4) ◽  
pp. 643-649 ◽  
Author(s):  
Syed Q. Alam ◽  
Bassima S. Alam
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Phosphatidyl Ethanolamine ◽  
Control Diet ◽  
Deficient Diet ◽  
Adult Rats ◽  
Male Adult ◽  
Submandibular Salivary Glands ◽  
Deficient Group

Male adult rats were fed choline deficient and a choline-supplemented diet for 3 weeks. Half the rats from each group were injected with isoprenaline (16 mg/kg body wt.) and the remainder with saline. After 2 and 8 hours, rats were sacrificed, their submandibular salivary glands (SMSG) were disected out, and extracted for lipids. The fatty acid composition of total lipids and some neutral and phospholipid fractions were determined. Isoprenaline administration resulted in a slightly higher level of oleic acid in SMSG of rats fed choline-deficient but not the control diet. There was an increase in the free fatty acid (FFA) concentrations of the gland after 2 hours of isoprenaline treatment in rats fed the control diet; no such increase was observed in the choline-deficient group. The fatty acid composition of the FFA fraction was also slightly changed as a result of isoprenaline treatment, but only in the choline-deficient group. The fatty acid composition of triglyceride (TG), phosphatidyl choline (PC), and phosphatidyl ethanolamine (PE) fractions was not changed.

Platelet Aggregation in Finnish Men and Its Relation to Fatty Acids in Platelets, Plasma and Adipose Tissue

1985 ◽  
Vol 54 (03) ◽  
pp. 563-569 ◽  
Author(s):  
M K Salo ◽  
E Vartiainen ◽  
P Puska ◽  
T Nikkari
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Platelet Aggregation ◽  
Acid Composition ◽  
Saturated Fatty Acids ◽  
Free Living ◽  
Ω3 Fatty Acids ◽  
Induced Aggregation

SummaryPlatelet aggregation and its relation to fatty acid composition of platelets, plasma and adipose tissue was determined in 196 randomly selected, free-living, 40-49-year-old men in two regions of Finland (east and southwest) with a nearly twofold difference in the IHD rate.There were no significant east-southwest differences in platelet aggregation induced with ADP, thrombin or epinephrine. ADP-induced platelet secondary aggregation showed significant negative associations with all C20-C22 ω3-fatty acids in platelets (r = -0.26 - -0.40) and with the platelet 20: 5ω3/20: 4ω 6 and ω3/ ω6 ratios, but significant positive correlations with the contents of 18:2 in adipose tissue (r = 0.20) and plasma triglycerides (TG) (r = 0.29). Epinephrine-induced aggregation correlated negatively with 20: 5ω 3 in plasma cholesteryl esters (CE) (r = -0.23) and TG (r = -0.29), and positively with the total percentage of saturated fatty acids in platelets (r = 0.33), but had no significant correlations with any of the ω6-fatty acids. Thrombin-induced aggregation correlated negatively with the ω3/6ω ratio in adipose tissue (r = -0.25) and the 20: 3ω6/20: 4ω 6 ratio in plasma CE (r = -0.27) and free fatty acids (FFA) (r = -0.23), and positively with adipose tissue 18:2 (r = 0.23) and 20:4ω6 (r = 0.22) in plasma phospholipids (PL).The percentages of prostanoid precursors in platelet lipids, i. e. 20: 3ω 6, 20: 4ω 6 and 20 :5ω 3, correlated best with the same fatty acids in plasma CE (r = 0.32 - 0.77) and PL (r = 0.28 - 0.74). Platelet 20: 5ω 3 had highly significant negative correlations with the percentage of 18:2 in adipose tissue and all plasma lipid fractions (r = -0.35 - -0.44).These results suggest that, among a free-living population, relatively small changes in the fatty acid composition of plasma and platelets may be reflected in significant differences in platelet aggregation, and that an increase in linoleate-rich vegetable fat in the diet may not affect platelet function favourably unless it is accompanied by an adequate supply of ω3 fatty acids.

Health Benefits of Pumpkin Seed and Nutrition Profile of 35 Pumpkin Accessions

EDIS ◽  
2017 ◽  
Vol 2017 (6) ◽  
Author(s):  
Geoffrey M. Meru ◽  
Yuqing Fu ◽  
Dayana Leyva ◽  
Paul Sarnoski ◽  
Yavuz Yagiz
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Health Benefits ◽  
Pumpkin Seed ◽  
Production Practices

This article aims to summise production and nutrition aspects of pumpkin seed. Specifically, it focuses on health benefits of the seeds, production practices and provides data on the oil, protein and fatty acid composition of 35 pumpkin accessions.  

The effect of SNP (rs174537) in FADS1 gene on fatty acid composition in serum lipids

2020 ◽  
Author(s):  
Tereza Metelcová ◽  
Markéta Vaňková ◽  
Hana Zamrazilová ◽  
Milena Hovhannisyan ◽  
Eva Tvrzická ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Serum Lipids
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