CONTINUOUS INTRAVENOUS INFUSION IN THE RAT, AND THE EFFECT ON THE ISLETS OF LANGERHANS OF THE CONTINUOUS INFUSION OF GLUCOSE

1954 ◽  
Vol 32 (1) ◽  
pp. 428-433 ◽  
Author(s):  
B. Kinash ◽  
R. E. Haist
Keyword(s):  
Body Weight ◽  
Continuous Infusion ◽  
Islets Of Langerhans ◽  
Intravenous Infusion ◽  
Continuous Intravenous Infusion ◽  
Islet Tissue ◽  
Pancreas Weight

A method is described for the continuous intravenous infusion of fluids in the unanesthetized rat. When rats were infused continuously with glucose solutions for 6–14 days the total amount of islet tissue was greatly increased, as compared to that of saline-infused controls. This increase was evident also when considered in relation to pancreas weight or body weight.

CONTINUOUS INTRAVENOUS INFUSION IN THE RAT, AND THE EFFECT ON THE ISLETS OF LANGERHANS OF THE CONTINUOUS INFUSION OF GLUCOSE

1954 ◽  
Vol 32 (4) ◽  
pp. 428-433 ◽  
Author(s):  
B. Kinash ◽  
R. E. Haist
Keyword(s):  
Body Weight ◽  
Continuous Infusion ◽  
Islets Of Langerhans ◽  
Intravenous Infusion ◽  
Continuous Intravenous Infusion ◽  
Islet Tissue ◽  
Pancreas Weight

A method is described for the continuous intravenous infusion of fluids in the unanesthetized rat. When rats were infused continuously with glucose solutions for 6–14 days the total amount of islet tissue was greatly increased, as compared to that of saline-infused controls. This increase was evident also when considered in relation to pancreas weight or body weight.

THE INFLUENCE OF THE THYROID GLAND ON THE ISLETS OF LANGERHANS AND THE PANCREAS

1955 ◽  
Vol 33 (1) ◽  
pp. 380-384
Author(s):  
B. Kinash ◽  
R. E. Haist
Keyword(s):  
Body Weight ◽  
Thyroid Gland ◽  
Islets Of Langerhans ◽  
Great Reduction ◽  
Islet Tissue ◽  
Hypophysectomized Rats ◽  
Pancreas Weight ◽  
Intact Rats

When sufficiently large amounts of desiccated thyroid gland were administered to intact or hypophysectomized rats there was an increase in the weight of the pancreas, weight of the islets of Langerhans, and islet weight per unit of body weight. In intact rats the concentration of islet tissue in the pancreas was not significantly altered, but in hypophysectomized animals the concentration of islet tissue in the pancreas was reduced because of the large increase in pancreas weight. The great reduction in pancreas weight occasioned by hypophysectomy was to a large extent prevented by the administration of desiccated thyroid gland.

THE INFLUENCE OF THE THYROID GLAND ON THE ISLETS OF LANGERHANS AND THE PANCREAS

1955 ◽  
Vol 33 (3) ◽  
pp. 380-384 ◽  
Author(s):  
B. Kinash ◽  
R. E. Haist
Keyword(s):  
Body Weight ◽  
Thyroid Gland ◽  
Islets Of Langerhans ◽  
Great Reduction ◽  
Islet Tissue ◽  
Hypophysectomized Rats ◽  
Pancreas Weight ◽  
Intact Rats

When sufficiently large amounts of desiccated thyroid gland were administered to intact or hypophysectomized rats there was an increase in the weight of the pancreas, weight of the islets of Langerhans, and islet weight per unit of body weight. In intact rats the concentration of islet tissue in the pancreas was not significantly altered, but in hypophysectomized animals the concentration of islet tissue in the pancreas was reduced because of the large increase in pancreas weight. The great reduction in pancreas weight occasioned by hypophysectomy was to a large extent prevented by the administration of desiccated thyroid gland.

scholarly journals Prolonged Cefoxitin Infusion Using Mobile Elastomeric Infusors In Outpatients With Bone And Joint Infection

2018 ◽  
Vol 3 (4) ◽  
pp. 182-186 ◽  
Author(s):  
Zoé Cavalli ◽  
Agathe Becker ◽  
Alexie Bosch ◽  
Anne Conrad ◽  
Claire Triffault-Filit ◽  
...  
Keyword(s):  
Continuous Infusion ◽  
Intravenous Infusion ◽  
Joint Infection ◽  
Continuous Intravenous Infusion ◽  
Reference Center ◽  
Bone And Joint Infection ◽  
The Stability ◽  
Regional Reference

Abstract. We reviewed all outpatients with bone and joint infection treated with cefoxitin in continuous intravenous infusion using mobile elastomeric infusors in our regional reference center between 2014 and 2017. The stability of cefoxitin provides an interesting and well-tolerated alternative for continuous infusion in outpatients with polymicrobial bone and joint infection.

Continuous infusion anaesthesia in baboons with alphaxolone-alphadolone

1983 ◽  
Vol 17 (3) ◽  
pp. 196-197 ◽  
Author(s):  
J. H. Cookson ◽  
F. J. Mills
Keyword(s):  
Continuous Infusion ◽  
Intravenous Infusion ◽  
Cumulative Effect ◽  
Uneventful Recovery ◽  
Continuous Intravenous Infusion ◽  
Rapid Induction

39 experiments were carried out in baboons using continuous intravenous infusion of alphaxalone-alphadolone as an anaesthetic for periods of up to 6 h. This steroid anaesthetic was found to be safe and reliable, with smooth, rapid induction, uneventful recovery, and no evidence of cumulative effect.

scholarly journals A simple technique for continuous intravenous infusion under neuroleptic tranquillization

1976 ◽  
Vol 10 (1) ◽  
pp. 69-72 ◽  
Author(s):  
H. Saarni ◽  
J. Viikari
Keyword(s):  
Continuous Infusion ◽  
Intravenous Infusion ◽  
Simple Technique ◽  
Continuous Intravenous Infusion ◽  
Tail Vein

A lateral tail vein of the rat is used as the route for continuous infusion. The animal is kept under neuroleptic tranquilisation during the infusion.

scholarly journals Insulin Affects Glucose Uptake by Muscle and Mammary Tissues of Lactating Ewes

1988 ◽  
Vol 41 (4) ◽  
pp. 453 ◽  
Author(s):  
D Leenanuruksa ◽  
P Niumsup ◽  
GH McDowell
Keyword(s):  
Skeletal Muscle ◽  
Insulin Secretion ◽  
Continuous Infusion ◽  
Plasma Glucose ◽  
Intravenous Infusion ◽  
Mammary Tissue ◽  
Continuous Intravenous Infusion ◽  
Short Term ◽  
Exogenous Glucose ◽  
Frequent Monitoring

Effects of insulin on exchanges of glucose across skeletal muscle and mammary tissue were measured in short-term studies in lactating ewes. Insulin secretion was suppressed by a primed/continuous infusion of somatostatin, then insulin was administered by continuous intravenous infusion of doses that were increased, in a step-wise manner, from 0 to 2 U h -I. Plasma glucose was maintained essentially constant by frequent monitoring and intravenous administration of exogenous glucose.

scholarly journals Gastro-intestinal Tract Function in Sheep Infused with Somatostatin

1985 ◽  
Vol 38 (4) ◽  
pp. 393 ◽  
Author(s):  
TN Barry ◽  
GJ Faichney ◽  
Carolyn Redekopp
Keyword(s):  
Continuous Infusion ◽  
Intravenous Infusion ◽  
Dry Matter ◽  
Intestinal Tract ◽  
Sampling Procedure ◽  
Continuous Intravenous Infusion ◽  
Tract Function ◽  
Pelleted Diet ◽  
Gastro Intestinal Tract

The effect of a 5-day continuous intravenous infusion of somatostatin (4�6 ng min- I kg-I) was studied, using anoestrous ewes given 791 g dry matter per day of a 60: 40 lucerne hay: oat grain pelleted diet from a continuously moving belt. 5ICr-EDTA, I03Ru-phenanthroline and lignin were used as markers to determine digesta mean retention times (MRT) by a continuous infusion-total sampling procedure.

scholarly journals Splanchnic retention of intraduodenal and intrajejunal glucose in healthy adults

1998 ◽  
Vol 275 (4) ◽  
pp. E709-E716 ◽  
Author(s):  
G. Livesey ◽  
P. D. G. Wilson ◽  
M. A. Roe ◽  
R. M. Faulks ◽  
L. M. Oram ◽  
...  
Keyword(s):  
Body Weight ◽  
Intravenous Infusion ◽  
Isotonic Saline ◽  
Systemic Circulation ◽  
Healthy Adults ◽  
Continuous Intravenous Infusion ◽  
Distal Intestine ◽  
Healthy Humans ◽  
Hepatic Glucose ◽  
Proximal Intestine

Estimates of the spanchnic retention and appearance in the systemic circulation of orally administered glucose vary among laboratories even after recently identified sources of error have been accounted for [Livesey, G., P. D. G. Wilson, J. R. Dainty, J. C. Brown, R. M. Faulks, M. A. Roe, T. A. Newman, J. Eagles, F. A. Mellon, and R. Greenwood. Am. J. Physiol. 275 ( Endocrinol. Metab. 38): E717–E728, 1998]. We questioned whether, in healthy humans,d-glucose delivered intraluminally to the midjejunum appeared systemically as extensively as that delivered intraduodenally. Subjects were infused over a period of 90 min with 50 g of glucose in 1 liter of isotonic saline (incorporating 0.5 gd-[13C6]glucose) per 70 kg of body weight. Infusions were via enteral tubes terminating ∼15 and 100 cm postpylorus. The systemic appearance of glucose was monitored by means of a primed-continuous intravenous infusion ofd-[6,6-2H2]glucose. Whereas 98 ± 2% ( n = 7) of the duodenally infused glucose appeared in the systemic circulation, only 35 ± 9% ( n = 7) of midjejunally infused glucose did so, implying that 65 ± 9% was retained in the splanchnic bed. Either glucose was less efficiently absorbed at the midintestinal site or hepatic glucose sequestration was increased 10-fold, or both. The proximal intestine plays a key role in the delivery of glucose to the systemic circulation, and the distal intestine potentially delivers more glucose to the liver.

A new system for continuous intravenous infusion of pigs

1996 ◽  
Vol 30 (1) ◽  
pp. 75-78 ◽  
Author(s):  
D. J. van Kleef
Keyword(s):  
Continuous Infusion ◽  
Psychological Stress ◽  
Intravenous Infusion ◽  
Cost Effective ◽  
Continuous Intravenous Infusion ◽  
Restricted Movement ◽  
Physical Discomfort ◽  
Infusion Tube ◽  
New System

The swivel system described has been used by ILOB-TNO for prolonged periods of continuous infusion. It allows for less restricted movement of animals. The swivel prevents the infusion tube from twisting. The swivel system is simple, safe to operate and cost-effective. Animals have greater movement, can stretch and turn around. The physical discomfort and psychological stress of restricted movement are greatly reduced. The potentially complicating/confusing effects on the measurements taken during an experiment are reduced.

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