Special Issue celebrating the 125th Anniversary of the Faculty of Medicine at the University of Manitoba / Numéro spécial célébrant le 125e anniversaire de la faculté de médecine de l’Université du Manitoba

2009 ◽  
Vol 87 (10) ◽  
Keyword(s):  
Special Issue ◽  
125Th Anniversary ◽  
University Of Manitoba ◽  
The University

Cyanobacterial toxins and liver diseaseThis article is one of a selection of papers published in a special issue celebrating the 125th anniversary of the Faculty of Medicine at the University of Manitoba.

2009 ◽  
Vol 87 (10) ◽  
pp. 773-788 ◽  
Author(s):  
M.A. Labine ◽  
G.Y. Minuk
Keyword(s):  
Special Issue ◽  
Blue Green Algae ◽  
125Th Anniversary ◽  
Life Threatening ◽  
University Of Manitoba ◽  
The University ◽  
Present Understanding ◽  
Insight Into ◽  
Freshwater Environments ◽  
Selection Of

Blue-green algae, also known as cyanobacteria, produce a variety of toxins, some of which have been implicated in the pathogenesis of severe and potentially life-threatening diseases in humans. As the growth of cyanobacteria within freshwater lakes increases worldwide, it is important to review our present understanding of their toxicity and potential carcinogenicity to gain insight into how these organisms impact human health. This review addresses each of these topics, with special emphasis given to cyanobacterial hepatotoxins within freshwater environments.

scholarly journals Cardiolipin synthesis is required to support human cholesterol biosynthesis from palmitate upon serum removal in Hela cellsThis article is one of a selection of papers published in a special issue celebrating the 125th anniversary of the Faculty of Medicine at the University of Manitoba.

2009 ◽  
Vol 87 (10) ◽  
pp. 813-820 ◽  
Author(s):  
Kristin D. Hauff ◽  
Seok-Yong Choi ◽  
Michael A. Frohman ◽  
Grant M. Hatch
Keyword(s):  
Hela Cells ◽  
De Novo ◽  
Cholesterol Biosynthesis ◽  
Molar Ratio ◽  
Serum Free ◽  
Mock Control ◽  
125Th Anniversary ◽  
University Of Manitoba ◽  
The University ◽  
Serum Free Conditions

We examined whether cardiolipin (CL) synthesis was required to support cholesterol (CH) production from palmitate in Hela cells. Knockdown of human cardiolipin synthase-1 (hCLS1) in Hela cells has been shown to reduce CL synthesis. Therefore Hela cells stably expressing shRNA for hCLS1 and mock control cells were incubated for 16 h with [14C(U)]palmitate bound to albumin (1:1 molar ratio) in the absence or presence of serum. Knockdown of hCLS1 in Hela cells resulted in a reduction in [14C(U)]palmitate incorporation into CL and CH. This reduction in [14C(U)]palmitate incorporation into CH was most pronounced during incubation under serum-free conditions. The reduction in [14C(U)]palmitate incorporation into CH was not due to alterations in total uptake of [14C(U)]palmitate into cells or altered palmitate metabolism, since [14C(U)]palmitate incorporation into phosphatidylcholine, the major [14C(U)]palmitate-containing lipid, and its immediate precursor, 1,2-diacyl-sn-glycerol, were unaffected by hCLS1 knockdown. In addition, knockdown of hCLS1 did not affect CH pool size, indicating that CH catabolism was unaltered. Hydroxymethylglutaryl coenzyme A reductase enzyme activity and its mRNA expression were reduced by knockdown of hCLS1 and this was most pronounced in Hela cells cultured under serum-free conditions. These data indicate that CL synthesis is required to support human de novo CH biosynthesis under conditions of increased demand for CH.

Obesity, syndrome X, and diabetes: the role of HISS-dependent insulin resistance altered by sucrose, an antioxidant cocktail, and ageThis article is one of a selection of papers published in a special issue celebrating the 125th anniversary of the Faculty of Medicine at the University of Manitoba.

2009 ◽  
Vol 87 (10) ◽  
pp. 873-882 ◽  
Author(s):  
Zhi Ming ◽  
Dallas J. Legare ◽  
W. Wayne Lautt
Keyword(s):  
Bioelectrical Impedance ◽  
Nutrient Status ◽  
Postprandial Hyperglycemia ◽  
Syndrome X ◽  
Slow Development ◽  
125Th Anniversary ◽  
University Of Manitoba ◽  
The University

Absence of meal-induced insulin sensitization (AMIS) results in a predictable progression of dysfunctions, including postprandial hyperglycemia, compensatory hyperinsulinemia, resultant hyperlipidemia, increased oxidative stress, and obesity, progressing to syndrome X and diabetes. To test the ‘AMIS syndrome’ hypothesis we used 3 known means of producing graded and progressive changes in meal-induced insulin sensitization in rats. We used an aging model (9, 26, and 52 weeks), associated with a slow development of AMIS; a low-dose sucrose supplement model to accelerate the development of AMIS; and an antioxidant cocktail (S-adenosylmethionine, vitamin E, and vitamin C) to protect against the effect of the sucrose on meal-induced insulin sensitization. Adiposity was assessed from weighed regional fat masses and bioelectrical impedance. AMIS developed with age, was increased by sucrose supplementation, and was inhibited by the antioxidant cocktail. AMIS correlated with postprandial hyperglycemia, hyperinsulinemia, hyperlipidemia, and with adiposity (r2 = 0.7–0.8) regardless of age or nutrient status. The range of degrees of AMIS, established over time with these models, afforded the tool with which to test the AMIS syndrome and further the argument that AMIS is the first metabolic defect that cumulatively leads to a predictable series of homeostatic disturbances and dysfunctions, including obesity and type 2 diabetes.

Health and Medical Informatics Education

1994 ◽  
Vol 33 (03) ◽  
pp. 246-249 ◽  
Author(s):  
R. Haux ◽  
F. J. Leven ◽  
J. R. Moehr ◽  
D. J. Protti
Keyword(s):  
Health Care ◽  
Health Information ◽  
Medical Informatics ◽  
Health Informatics ◽  
Information Science ◽  
Management Program ◽  
Science Program ◽  
Special Issue ◽  
Academic Degree ◽  
The University

Abstract:Health and medical informatics education has meanwhile gained considerable importance for medicine and for health care. Specialized programs in health/medical informatics have therefore been established within the last decades.This special issue of Methods of Information in Medicine contains papers on health and medical informatics education. It is mainly based on selected papers from the 5th Working Conference on Health/Medical Informatics Education of the International Medical Informatics Association (IMIA), which was held in September 1992 at the University of Heidelberg/Technical School Heilbronn, Germany, as part of the 20 years’ celebration of medical informatics education at Heidelberg/Heilbronn. Some papers were presented on the occasion of the 10th anniversary of the health information science program of the School of Health Information Science at the University of Victoria, British Columbia, Canada. Within this issue, programs in health/medical informatics are presented and analyzed: the medical informatics program at the University of Utah, the medical informatics program of the University of Heidelberg/School of Technology Heilbronn, the health information science program at the University of Victoria, the health informatics program at the University of Minnesota, the health informatics management program at the University of Manchester, and the health information management program at the University of Alabama. They all have in common that they are dedicated curricula in health/medical informatics which are university-based, leading to an academic degree in this field. In addition, views and recommendations for health/medical informatics education are presented. Finally, the question is discussed, whether health and medical informatics can be regarded as a separate discipline with the necessity for specialized curricula in this field.In accordance with the aims of IMIA, the intention of this special issue is to promote the further development of health and medical informatics education in order to contribute to high quality health care and medical research.

Centres for Health Evidence Demonstration Project

2013 ◽  
Author(s):  
Tracy Stewart ◽  
Denise Koufogiannakis ◽  
Robert S.A. Hayward ◽  
Ellen Crumley ◽  
Michael E. Moffatt
Keyword(s):  
Evidence Based Practice ◽  
Demonstration Project ◽  
Evidence Based ◽  
Research Opportunities ◽  
University Of Alberta ◽  
Information Usage ◽  
University Of Manitoba ◽  
The University ◽  
Hospital Wards ◽  
Support Evidence

This paper will report on the establishment of the Centres for Health Evidence (CHE) Demonstration Project in both Edmonton at the University of Alberta and in Winnipeg at the University of Manitoba. The CHE Project brings together a variety of partners to support evidence-based practice using Internet-based desktops on hospital wards. There is a discussion of the CHE's cultural and political experiences. An overview of the research opportunities emanating from the CHE Project is presented as well as some early observations about information usage.

scholarly journals Introduction: Transdiasporic Rencontres in Việt Kiều Literature

2018 ◽  
Vol 15 (1-2) ◽  
pp. 1-5
Author(s):  
Alexandra Kurmann ◽  
Tess Do
Keyword(s):  
New Caledonia ◽  
Literary Texts ◽  
Special Issue ◽  
Contemporary Writing ◽  
The University ◽  
First Time ◽  
Vietnamese Diaspora

This special issue follows a conference entitled ‘Rencontres: A Gathering of Voices of the Vietnamese Diaspora’ that was held at the University of Melbourne, December 1-2 in 2016 and which sought to enable, for the first time, the titular transdiasporic rencontres or encounters between international authors of the Vietnamese diaspora. The present amalgam of previously unpublished texts written by celebrated Francophone and Anglophone authors of Vietnamese descent writing in France, New Caledonia and Australia today is the result of the intercultural exchanges that took place during that event. Literary texts by Linda Lê, Anna Moï and Thanh-Van Tran-Nhut are followed by writerly reflections on the theme of transdiasporic encounters from Hoai Huong Nguyen, Jean Vanmai and Hoa Pham. Framing and enriching these texts, scholarly contributions by established experts in the field consider the literary, cultural and linguistic transfers that characterize contemporary writing by authors of Vietnamese origin across the Francophone world. Ce volume spécial réunit les Actes du colloque ‘Rencontres : A Gathering of Voices of the Vietnamese Diaspora’ qui s’est tenue à l’Université de Melbourne les 1er et 2 décembre 2016 et qui visait à faciliter, pour la première fois, les rencontres entre les auteurs, chercheurs et universitaires internationaux de la diaspora vietnamienne. Les fruits de leurs échanges interculturels y sont réunis dans ce présent recueil sous deux formes complémentaires : d’un côté, les articles d’experts en littérature francophone comparée ; de l’autre, les contributions créatives de célèbres auteurs francophones et anglophones d’origine vietnamienne basés aujourd’hui en France, en Nouvelle Calédonie et en Australie. Les textes littéraires de Linda Lê, Anna Moï et Thanh-Van Tran-Nhut, suivis de réflexions d’auteurs par Hoai Huong Nguyen, Hoa Pham et Jean Vanmai sur le thème des rencontres transdiasporiques, se retrouvent enrichis par les études savantes menées sur les transferts littéraires, culturelles et linguistiques qui caractérisent l’écriture contemporaine des écrivains d’origine vietnamienne dans le monde francophone.

An Interview with Marilyn Strathern: Kinship and Career

2014 ◽  
Vol 31 (2-3) ◽  
pp. 263-281 ◽  
Author(s):  
Janet Carsten
Keyword(s):  
Cultural Anthropology ◽  
Social Anthropology ◽  
Special Issue ◽  
University Of Cambridge ◽  
The University

The interview was conducted in September 1996 in Cambridge. Marilyn Strathern (MS) and Janet Carsten (JC) had been colleagues at the University of Manchester’s Department of Social Anthropology until September 1993, when Marilyn Strathern left to take up the William Wyse Professorship at the University of Cambridge, where she remained until retirement in 2008. Janet Carsten joined Edinburgh in October of the same year, where she is presently Professor of Social and Cultural Anthropology. (Supplementary questions, reflecting back on the earlier interview, were put to Marilyn Strathern by the editors of the special issue in 2013.)

The Production of 123I and 84Rb at the University of Manitoba Cyclotron Laboratory

1979 ◽  
Vol 26 (2) ◽  
pp. 2269-2270 ◽  
Author(s):  
M. I. Gusdal ◽  
J. S. C. McKee ◽  
M. Billinghurst ◽  
J. B. Sutherland ◽  
G. P. Sharma
Keyword(s):  
University Of Manitoba ◽  
The University

scholarly journals Meet Our International Editorial Consultants

2015 ◽  
Vol 40 (1) ◽  
pp. 6-8
Author(s):  
Jennifer Lehmann
Keyword(s):  
New Zealand ◽  
Guest Editor ◽  
Special Issue ◽  
Regular Feature ◽  
Professional Practitioners ◽  
The University

Children Australia has had the support and advice of many academic and professional practitioners over its many years of publication, with a number of people serving as Editorial Consultants. More recently, a number of international academics have joined our ranks, following in the footsteps of Nicola Taylor, Director of the Children's Issues Centre at the University of Otago, in Auckland, New Zealand, who was the first of our overseas academics. Nicola was the Guest Editor of a Special Issue some time ago, heralding what is now a more regular feature of the journal – encouraging collections of papers addressing specific topics.

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