Variability in asthma: symptom perception, care, and outcomesThis paper is one of a selection of papers published in this Special Issue, entitled Young Investigators' Forum.

2007 ◽  
Vol 85 (1) ◽  
pp. 149-154 ◽  
Author(s):  
M. Diane Lougheed

Asthma remains a global respiratory health concern. Substantial variations in asthma outcomes persist in Canada despite the dissemination of national management guidelines. Many factors and their interactions presumably contribute to variations in outcomes, including asthma prevalence, severity, symptom recognition, self-management behaviour, access to care, and management. This article reviews the physiology of symptom perception in asthma, specifically the role of dynamic lung hyperinflation (DH) on the perception of the intensity and quality of dyspnea in asthma, and the link between blunted perception and life-threatening asthma. Additionally, the magnitude and correlates of regional variation in emergency department visit rates and hospitalizations for asthma in Ontario are reviewed.

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 977-982
Author(s):  
Mohamed J. Saadh ◽  
Bashar Haj Rashid M ◽  
Roa’a Matar ◽  
Sajeda Riyad Aldibs ◽  
Hala Sbaih ◽  
...  

SARS-COV2 virus causes Coronavirus disease (COVID-19) and represents the causative agent of a potentially fatal disease that is of great global public health concern. The novel coronavirus (2019) was discovered in 2019 in Wuhan, the market of the wet animal, China with viral pneumonia cases and is life-threatening. Today, WHO announces COVID-19 outbreak as a pandemic. COVID-19 is likely to be zoonotic. It is transmitted from bats as intermediary animals to human. Also, the virus is transmitted from human to human who is in close contact with others. The computerized tomographic chest scan is usually abnormal even in those with no symptoms or mild disease. Treatment is nearly supportive; the role of antiviral agents is yet to be established. The SARS-COV2 virus spreads faster than its two ancestors, the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), but has lower fatality. In this article, we aimed to summarize the transmission, symptoms, pathogenesis, diagnosis, treatment, and vaccine to control the spread of this fatal disease.


Author(s):  
Mohamad Hossein Pourhanifeh ◽  
Kazem Abbaszadeh-Goudarzi ◽  
Mohammad Goodarzi ◽  
Sara G.M. Piccirillo ◽  
Alimohammad Shafiee ◽  
...  

: Melanoma is the most life-threatening and aggressive class of skin malignancies. The incidence of melanoma has steadily increased. Metastatic melanoma is greatly resistant to standard anti-melanomatreatments such as chemotherapy, and 5-year survival rate of cases with melanoma who have metastatic form of disease is less than 10%. The contributing role of apoptosis, angiogenesis and autophagy in the pathophysiology of melanoma has been previously demonstrated. Thus, it is extremely urgent to search for complementary therapeutic approachesthat couldenhance the quality of life of subjects and reduce treatment resistance and adverse effects. Resveratrol, known as a polyphenol component present in grapes and some plants, has anti-cancer properties due to its function as an apoptosis inducer in tumor cells, and anti-angiogenic agent to prevent metastasis. However, more clinical trials should be conducted to prove resveratrol efficacy. : Herein, for first time, we summarize current knowledge of anti-cancerous activities of resveratrol in melanoma.


2020 ◽  
Vol 16 (5) ◽  
pp. 675-688
Author(s):  
Shamsi Abbasalizadeh ◽  
Behzad Ebrahimi ◽  
Aslan Azizi ◽  
Rogaye Dargahi ◽  
Maryam Tayebali ◽  
...  

Constipation is a common public health concern experienced by all individuals during their life affecting the quality of life. In this paper, we aimed to provide an overview of the existing evidence regarding the role of food ingredients, including bran, prune, fig, kiwifruit, and flax-seed in constipation treatment. We searched Scopus, Pub Med, and Science Direct by using the keywords, “laxative foods” and “constipation”, for searching studies assessing laxative food ingredients and their beneficial effects on constipation treatment and/or control. Lifestyle modifications such as increasing dietary fiber and fluid intake and daily exercise are the proposed first line treatments for constipation. Optimizing ‘diet’ as an efficient lifestyle factor may contribute to the well-being of patients. The use of laxative food ingredients including bran, prune, fig, kiwifruit, flax-seed, probiotics, and prebiotics is a convenient alternative to cope with constipation. According to previous findings, laxative food ingredients could be considered as effective treatments for subjects suffering from constipation. Many studies have assessed the pharmacological and non-pharmacological roles of these ingredients in treating constipation, however, their importance has not been thoroughly investigated.


Author(s):  
Dr.Suraj Kumbar ◽  
Dr.Lohith BA ◽  
Dr.Ashvinikumar M ◽  
Dr. Amritha R ◽  
Dr. Shameem Banu

We are in technical era where there is more of sedentary life style and stress along with this urbanization is affecting our quality of food and health. This is leading to many lifestyle disorders and hormonal imbalances in our body. Hypothyroidism one among the endocrinal disorder. Thyroid is an endocrinal gland secrets T3 and T4 hormones regulated by TSH which is secreted by Pituitary gland. These hormones have two major effects on the body, 1) To increase the overall metabolic rate in the body 2) To stimulate growth in children. Hypothyroidism is common health issue in India. The highest prevalence of hypothyroidism (13.1%) is noted in people aged 46-54yrs old. With people aged 18-35 yrs being less affected (7.5%). To prevent these hazards Panchakarma is beneficiary to maintain metabolic rate. Here an attempt is made to diagnose hypothyroidism in the light of Ayurveda and management guidelines through Panchakarma.


Hematology ◽  
2014 ◽  
Vol 2014 (1) ◽  
pp. 277-286 ◽  
Author(s):  
Holly L. Geyer ◽  
Ruben A. Mesa

Abstract Myeloproliferative neoplasms, including polycythemia vera (PV), essential thrombocythemia, and myelofibrosis (MF) (both primary and secondary), are recognized for their burdensome symptom profiles, life-threatening complications, and risk of progression to acute leukemia. Recent advancements in our ability to diagnose and prognosticate these clonal malignancies have paralleled the development of MPN-targeted therapies that have had a significant impact on disease burden and quality of life. Ruxolitinib has shown success in alleviating the symptomatic burden, reducing splenomegaly and improving quality of life in patients with MF. The role and clinical expectations of JAK2 inhibition continues to expand to a variety of investigational arenas. Clinical trials for patients with MF focus on new JAK inhibitors with potentially less myelosuppression (pacritinib) or even activity for anemia (momelotinib). Further efforts focus on combination trials (including a JAK inhibitor base) or targeting new pathways (ie, telomerase). Similarly, therapy for PV continues to evolve with phase 3 trials investigating optimal frontline therapy (hydroxyurea or IFN) and second-line therapy for hydroxyurea-refractory or intolerant PV with JAK inhibitors. In this chapter, we review the evolving data and role of JAK inhibition (alone or in combination) in the management of patients with MPNs.


2021 ◽  
Vol 21 (83) ◽  
Author(s):  
Gabriela Marchiori do Carmo Azzolin

Objetivo: descrever a atuação do enfermeiro auditor na qualidade da assistência a saúde. Método: trata-se de uma revisão integrativa de artigos publicados no período de 2015 a 2020. A pesquisa e seleção dos artigos foi realizada nas bases de dados: BEDENF, LILACS e MEDLINE, por meio dos descritores “Enfermagem”, “Auditoria de enfermagem” , “Registros de enfermagem” e “ Qualidade da assistência à saúde”. Os critérios de inclusão foram artigos online gratuitos, com textos completos, publicados de 2015 a 2020, nos idiomas português e inglês. Resultados: foram selecionados 11 artigos, por cumprirem os critérios estabelecidos no estudo. Na análise dos resultados foi possível evidenciar a importância significativa da qualidade dos registros no processo de enfermagem. Conclusão: a atuação da enfermagem na auditoria tem ganhado notoriedade nos últimos anos, por ser de grande relevância para a qualidade da assistência prestada e abranger muito mais que a gestão de custos.Palavras-chave: Enfermagem; Auditoria de enfermagem; Registros de enfermagem; Qualidade da assistência à saúde. The auditor's nurse's performance in the quality of health care: integrative bibliographic review ABSTRACTObjective: to describe the role of the nurse auditor in the quality of health care. Method: this is an integrative review of articles published from 2015 to 2020. The research and selection of articles was carried out in the databases: BEDENF, LILACS and MEDLINE, using the descriptors “Nursing”, “Nursing audit "," Nursing records "and" Quality of health care ". The inclusion criteria were free online articles, with full texts, published from 2015 to 2020, in Portuguese and English. Result: 11 articles were selected, as they meet the criteria established in the study. In the analysis of the results, it was possible to highlight the significant importance of the quality of the records in the nursing process. Conclusio: the role of nursing in the audit has gained notoriety in recent years, as it is of great relevance to the quality of care provided and covers much more than cost management.Keywords: Nursing; Nursing audit; Nursing records; Quality of health care.


2022 ◽  
pp. 212-229
Author(s):  
Ashfaq Ahmad Shah ◽  
Sumaira Qayoom ◽  
Amit Gupta ◽  
Aqueel Ur Rehman

Current research on phytochemicals is mainly focused on novel phenolic and polyphenolic compounds expressing their potential as therapeutic agents in various diseases like cancer, autoimmune diseases, cardiovascular disorders, diabetes, oxidative stress-related diseases, as well as their properties to inhibit the growth and proliferation of infectious agents. Among the human physiological disorders, one of the most severe endocrine metabolic diseases is Diabetes mellitus which is a clinical disease distinguished by a deficit in the production of insulin or resistance to the action of insulin. Globally, diabetes is an increasing health concern which is now emerging as an epidemic. About 700-800 plants are exhibiting anti-diabetic activity that has been studied. As far as nanotechnology in diabetes research is concerned, it has made possible the buildout of novel glucose measurement as well as insulin delivery modalities that possess the potential to excellently enhance the quality of life of the diabetic patient.


Author(s):  
Iis Warlinda ◽  
Agus Perdana Windarto ◽  
M Fauzan

School is a place for students to gain knowledge. Every school has a goal which is to improve the quality of the education world, as well as the MTS Pembina Maligas Bayu school. To realize this goal there must be improvements in service, teaching and assessment in order to make a quality school. In this case the homeroom teacher is faced with a problem that is the selection of high achieving students who fit the criteria desired by the school. The purpose of this study is to analyze which factors are the most dominant in determining student achievement. The selection of high achieving students has many factors and has different values, so we need an Analytic Network Process (ANP) method to overcome them. Analytic Network Process (ANP) methods including decision support system techniques, Analytic Network Process (ANP) is a mathematical theory that allows dealing with interrelated factors and feedback in a structured manner. The data of this study came from student questionnaires which had a rating of 1-10. With alternative morals (A1), Grades (A2), Discipline (A3), Absence (A4), The role of the teacher (A5). Whereas A1 0.16%, A2 0.02%, A3 0.02%, A4 0.07% and A5 0.06%. It is hoped that this research can provide input to the MTS Pembina schools to focus on the dominant factor in the selection of outstanding students so as to increase the number of outstanding students.


Author(s):  
D. Zawieska ◽  
J. Markiewicz ◽  
M. Łuba

<p><strong>Abstract.</strong> In the community historical objects play the role of witnesses of the past history. This creates an obligation to preserve and reconstruct them for future generations. Photogrammetric methods have been applied for those purposes for many years. In the process of development of inventory documentation, the key aspects related to the selection of appropriate measuring methods for particular objects and the creation of appropriate working conditions. At present, digital measuring techniques allow developing 3D photogrammetric documentation which is particularly valuable both, for conservators of historical objects, as well as for creating virtual museums. Particular attention should be paid to the utilisation of macro photography for that purpose which allows for recreating small fragments of historical details. The objective of this paper is to present possible use of macro photography for inventory of historical patterns engraved in brick walls of one of the cellars of the Royal Castle in Warsaw (Poland); they are called engravings or house marks. The cellar walls were made of bricks (20<span class="thinspace"></span>&amp;times;<span class="thinspace"></span>10<span class="thinspace"></span>cm) on the stone foundations, where a prison was located in the 17th century. Prisoners left their drawings of signs and crests. Bricks are destroyed, some of them are moss-grown, so many engravings are hardly visible and their depths vary between 3 and 5<span class="thinspace"></span>mm. The Canon 5D Mark II camera with the 50 mm macro lens was used to inventory engravings together with the shadow-free flash, mounted on the lens and a special frame with bolts, being the photogrammetric control network. To ensure the high quality of the 3D model, a network of photographs were acquired from two different distances; they were processed with the use of SfM/MVS algorithms implemented in Agisoft PhotoScan software. The aim of this paper is to discusses the impact of selection of control points on the accuracy of the orientation process, the impact of the point cloud density on correct projection of the digital surface, the influence of the DSM resolution on details of projection of shapes and selection of orthorectification and mosaicking parameters on the accuracy of orthoimage generation.</p>


2022 ◽  
Vol 2 (1) ◽  
pp. 8-15
Author(s):  
RESTY KIANTINI

  The Ministry of Health Library is a builder library for libraries and librarians within the Ministry of Health spread throughout Indonesia. The success of the library is largely determined by the role of the librarian. Because the librarian is a profession that has a major contribution in realizing the noble ideals of the Indonesian nation in the intellectual life of the nation. Based on this, the Ministry of Health Library held a Selection of the Best Innovative Librarian. The method used in writing this scientific paper is best practice. Best Practice is an idea or new steps that make an outstanding, sustainable and innovative contribution in improving the process development and quality of education. Best Practice needs to be disseminated to others with various strategies in various places repeatedly so that it can be imitated and adopted by others. The selection of the Best Innovative Librarian was carried out in several stages. Starting from making the TOR for activities, entering activity items into the RKAKL, determining the theme of the activity, making guidelines, compiling a Committee Decree. The Best Innovative Librarian Assessment is done by looking at the completeness of documents, innovation papers and presentations. The one who gets the best score from the jury will be designated as the Best Innovative Librarian within the Ministry of Health. The Best Innovative Librarian 1 to 3 and expectations 1 to 3. The Best Innovative Librarian received awards and prizes at the Publication and Public Service Award Night of the Ministry of Health which was attended by the Minister of Health, Menpan-RB and the Head of the National Library. Librarians are the main key to the sustainability and success of a library. The selection of the Best Innovative Librarian was held as a form of appreciation and appreciation for librarians within the Ministry of Health. It is hoped that this activity can motivate librarians in the Ministry of Health to continue to work, innovate, perform and excel and have competitiveness with other professions. ABSTRAKPerpustakaan Kementerian Kesehatan merupakan perpustakaan pembina bagi perpustakaan dan pustakawan di lingkungan Kementerian Kesehatan yang tersebar di seluruh Indonesia. Keberhasilan perpustakaan sangat ditentukan oleh peran Pustakawan. Karena pustakawan merupakan profesi yang memiliki kontribusi besar dalam mewujudkan cita-cita luhur bangsa Indonesia dalam mencerdaskan kehidupan bangsa. Berdasarkan hal tersebut Perpustakaaan Kementerian Kesehatan menyelenggarakan Pemilihan Pustakawan Inovatif Terbaik. Metode yang digunakan dalam penulisan karya ilmiah ini adalah best practise. Best Practice adalah suatu ide atau langkah-langkah baru yang memberikan kontribusi luar biasa, berkesinambungan dan inovatif dalam memperbaiki pengembangan proses dan kualitas pendidikan. Best Practice perlu didiseminasikan kepada orang lain dengan berbagai strategi diberbagai tempat secara berulang-ulang sehingga dapat dicontoh dan diadopsi oleh orang lain. Pemilihan Pustakawan Inovatif Terbaik dilaksanakan melalui beberapa tahap. Diawali dari pembuatan TOR kegiatan, memasukkan butir kegiatan kedalam RKAKL, menentukan tema kegiatan, membuat pedoman, menyusun SK Kepanitiaan. Penilaian Pustakawan Inovatif Terbaik dilakukan dengan cara melihat kelengkapan dokumen, makalah inovasi dan presentasi. Yang mendapat nilai terbaik dari dewan juri akan ditetapkan sebagai Pustakawan Inovatif Terbaik di lingkungan Kementerian Kesehatan. Terpilih Pustakawan Inovatif Terbaik 1 sd 3 dan harapan 1 s/d 3. Pustakawan Inovatif Terbaik mendapatkan penghargaan dan hadiah di Malam Penghargaan Publikasi dan Pelayanan Publik Kementerian Kesehatan yang dihadiri oleh Menkes, Menpan-RB dan Kepala Perpusnas. Pustakawan menjadi kunci utama keberlangsungan dan keberhasilan sebuah perpustakaan. Pemilihan Pustakawan Inovatif Terbaik dilaksanakan sebagai suatu bentuk apresiasi dan penghargaan kepada pustakawan di lingkungan Kementerian Kesehatan. Diharapkan dengan adanya kegiatan ini dapat memotivasi pustakawan di lingkungan Kementerian Kesehatan untuk terus berkarya, berinovasi, berkinerja dan berprestasi serta memiliki daya saing dengan profesi lainnya.


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