Soluble polymer supported synthesis of a monosubstituted tetraaryl porphyrin

1989 ◽  
Vol 67 (3) ◽  
pp. 411-416 ◽  
Author(s):  
Y. Takahashi ◽  
J. E. Guillet ◽  
M. A. Winnik
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
High Yield ◽  
Separation And Purification ◽  
Poly Ethylene Glycol ◽  
Soluble Polymer ◽  
New Synthesis ◽  
Synthesis Strategy ◽  
Polymer Supported ◽  
Poly Ethylene

A new synthesis of monosubstituted tetraarylporphines is described based upon the soluble polymer supported synthesis strategy. Low molecular weight poly(ethylene glycol) is chloromethylated at both ends. These ends are then used to build up the polymer-bound ether of 5-(4′-hydroxymethyl)-10,15,20-tritolylporphine, which, after purification of the polymer, can be cleaved in high yield with TiCl4. While the method offers useful conveniences, such as the ease of separation and purification of the desired material, the overall yield is low: 100 mg from 40 g of polymer. Oligomerization of the polymer during chloromethylation increases the polymer molecular weight and thereby decreases the number of end groups per gram of polymer. Keywords: porphyrin, tetraaryl, monosubstituted poly(ethylene glycol) oligomerization, polymer-supported synthesis.

Soluble Polymer-Supported Synthesis of 4-Methyl Coumarin on Modified Poly(ethylene glycol)s

Synlett ◽  
2005 ◽  
Vol 2005 (08) ◽  
pp. 1296-1300 ◽  
Author(s):  
Graziella Tocco ◽  
Michela Begala ◽  
Giovanna Delogu ◽  
Gabriele Meli ◽  
Carmen Picciau ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Soluble Polymer ◽  
Polymer Supported ◽  
Poly Ethylene

Hydrolytically and Reductively Degradable High-Molecular-Weight Poly(ethylene glycol)s

2007 ◽  
Vol 208 (24) ◽  
pp. 2642-2653 ◽  
Author(s):  
Alena Braunová ◽  
Michal Pechar ◽  
Richard Laga ◽  
Karel Ulbrich
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
High Molecular Weight ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
High Molecular Weight Poly

Microporous Bio-Membrane Materials Based on High Molecular Weight Polylactide and Low Molecular Weight Poly(ethylene glycol)

2012 ◽  
Vol 567 ◽  
pp. 123-126
Author(s):  
Teng Fei Shen ◽  
Man Geng Lu ◽  
Li Yan Liang
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
High Weight ◽  
Low Molecular Weight ◽  
Poly Ethylene Glycol ◽  
Degradation Rates ◽  
Degradation Behaviors ◽  
The Mean ◽  
Poly Ethylene ◽  
Lower Glass Transition Temperature

In this work, microporous membrane biomaterials based on high weight molecular polylactide (PLA) and low molecular weight poly(ethylene glycol) (PEG) using rapid solvent evaporation method were prepared and investigated. The effect of PEG segments added on the thermal and degradation behaviors was studied. According to the results, produced PLA/PEG biomaterial has lower glass transition temperature (Tg)in comparison with neat PLA. It was also found that the degradation rates of the PLA/PEG biomaterials were significantly increased with adding of PEG, which explained by increasing hydrophilic groups. For better porous fixation, CL-blocked polyisocyanate (CL-bp), which was synthesized from reaction of isophorone diisocyanate (IPDI) with dimethylol propionic acid (DMPA) and Trimethylolpropane (TMP) followed by addition of caprolactam (CL), were introduced. The microporous forms were observed by the scanning electron microscope (SEM), which showed the mean diameters of prepared PLA/PEG microporous were around 10μm.

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