scholarly journals Plasticized poly(lactic acid) with low molecular weight poly(ethylene glycol): Mechanical, thermal, and morphology properties

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Buong Woei Chieng ◽  
Nor Azowa Ibrahim ◽  
Wan Md Zin Wan Yunus ◽  
Mohd Zobir Hussein
Keyword(s):  
Molecular Weight ◽  
Lactic Acid ◽  
Ethylene Glycol ◽  
Poly Lactic Acid ◽  
Low Molecular Weight ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Non-toxic polyester urethanes based on poly(lactic acid), poly(ethylene glycol) and lysine diisocyanate

2016 ◽  
Vol 32 (3) ◽  
pp. 225-241 ◽  
Author(s):  
Alena Pavelková ◽  
Pavel Kucharczyk ◽  
Zdenka Kuceková ◽  
Jiří Zedník ◽  
Vladimír Sedlařík
Keyword(s):  
Molecular Weight ◽  
Lactic Acid ◽  
Ethylene Glycol ◽  
Biomedical Applications ◽  
Hydrolytic Degradation ◽  
Chain Extension ◽  
Poly Lactic Acid ◽  
Side Reactions ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Poly(lactic acid)-based polymers are highly suitable for temporary biomedical applications, such as tissue support or drug delivery systems. Copolymers of different molecular weight based on poly(lactic acid) and poly(ethylene glycol) were prepared by polycondensation, catalysed by hydrochloric acid. A chain-extension reaction with l-lysine ethyl ester diisocyanate was employed afterwards to obtain polyester urethanes with enhanced properties. The GPC results showed that the molecular weights of the products reached about 50,000 g·mol−1 and the hydrolytic progress was rapid in the first 2 weeks; the drop in Mn equalled approximately 70%. Additionally, elemental analysis of the buffer medium proved that hydrolytic degradation was more rapid in the first stage. Tensile-strength testing revealed that ductility increased alongside reduced molecular weight of poly(ethylene glycol), also suggesting that polymer branching occurred due to side reactions of isocyanate. Based on the envisaged biomedical applications for these polymers, cytotoxicity tests were carried out and the cytotoxic effect was only moderate in the case of 100% polymer extract prepared according to ISO standard 10993-12. In their research, the authors focused on preparing metal-free, catalysed synthesis of polyester urethanes, which could prove useful to numerous biomedical applications.

The effect of poly(ethylene glycol) as plasticizer in blends of poly(lactic acid) and poly(butylene succinate)

2015 ◽  
Vol 133 (8) ◽  
pp. n/a-n/a ◽  
Author(s):  
Weraporn Pivsa-Art ◽  
Kazunori Fujii ◽  
Keiichiro Nomura ◽  
Yuji Aso ◽  
Hitomi Ohara ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Ethylene Glycol ◽  
Poly Lactic Acid ◽  
Poly Ethylene Glycol ◽  
Butylene Succinate ◽  
Poly Ethylene

Microporous Bio-Membrane Materials Based on High Molecular Weight Polylactide and Low Molecular Weight Poly(ethylene glycol)

2012 ◽  
Vol 567 ◽  
pp. 123-126
Author(s):  
Teng Fei Shen ◽  
Man Geng Lu ◽  
Li Yan Liang
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
High Weight ◽  
Low Molecular Weight ◽  
Poly Ethylene Glycol ◽  
Degradation Rates ◽  
Degradation Behaviors ◽  
The Mean ◽  
Poly Ethylene ◽  
Lower Glass Transition Temperature

In this work, microporous membrane biomaterials based on high weight molecular polylactide (PLA) and low molecular weight poly(ethylene glycol) (PEG) using rapid solvent evaporation method were prepared and investigated. The effect of PEG segments added on the thermal and degradation behaviors was studied. According to the results, produced PLA/PEG biomaterial has lower glass transition temperature (Tg)in comparison with neat PLA. It was also found that the degradation rates of the PLA/PEG biomaterials were significantly increased with adding of PEG, which explained by increasing hydrophilic groups. For better porous fixation, CL-blocked polyisocyanate (CL-bp), which was synthesized from reaction of isophorone diisocyanate (IPDI) with dimethylol propionic acid (DMPA) and Trimethylolpropane (TMP) followed by addition of caprolactam (CL), were introduced. The microporous forms were observed by the scanning electron microscope (SEM), which showed the mean diameters of prepared PLA/PEG microporous were around 10μm.

Biodegradable polymer blends of poly(lactic acid) and poly(ethylene glycol)

1997 ◽  
Vol 66 (8) ◽  
pp. 1495-1505 ◽  
Author(s):  
Mihir Sheth ◽  
R. Ananda Kumar ◽  
Vipul Dav� ◽  
Richard A. Gross ◽  
Stephen P. McCarthy
Keyword(s):  
Lactic Acid ◽  
Ethylene Glycol ◽  
Polymer Blends ◽  
Biodegradable Polymer ◽  
Poly Lactic Acid ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Plasticization of poly(lactide) with blends of tributyl citrate and low molecular weight poly(d,l-lactide)-b-poly(ethylene glycol) copolymers

2009 ◽  
Vol 45 (10) ◽  
pp. 2839-2848 ◽  
Author(s):  
Yahia Lemmouchi ◽  
Marius Murariu ◽  
Ana Margarida Dos Santos ◽  
Allan J. Amass ◽  
Etienne Schacht ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
Low Molecular Weight ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
Sign in / Sign up

Export Citation Format

Share Document