Thin-layer steady-state voltammetry under control by diffusion and migration

1988 ◽  
Vol 66 (5) ◽  
pp. 1333-1341 ◽  
Author(s):  
Christa L. Colyer ◽  
Paul J. J. Connelly ◽  
Heather L. Gordon ◽  
Keith B. Oldham
Keyword(s):  
Steady State ◽  
Thin Layer ◽  
Stringent Test ◽  
And Migration ◽  
Electrochemical Transport

Measurements of steady-state currents in thin-layer cells provide an opportunity to apply a stringent test of theories of electrochemical transport by simultaneous diffusion and migration. We have applied such a test and find the theory to be vindicated.

scholarly journals Potential Anticancer Activity of Crude Ethanol, Ethyl Acetate, and Water Extracts of Ephedra foeminea on Human Osteosarcoma U2OS Cell Viability and Migration

2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Eric Zadok Mpingirika ◽  
Ahmed El Hosseiny ◽  
Sheri Magdy Saleeb Bakheit ◽  
Rami Arafeh ◽  
Asma Amleh
Keyword(s):  
Steady State ◽  
Cell Viability ◽  
Ethyl Acetate ◽  
Anticancer Activity ◽  
Ethanol Extract ◽  
U2os Cell ◽  
Mrna Levels ◽  
Water Extracts ◽  
Human Osteosarcoma ◽  
And Migration

Medicinal plants are potential sources for a wide range of complex compounds with probable anticancer activity. Ephedra foeminea Forssk. (E. foeminea), a medicinal plant found in the Eastern Mediterranean, has recently been gaining popularity as a cancer remedy; there is, however, a paucity of empirical evidence supporting this claim. In this study, the effect of E. foeminea ethyl acetate, ethanol, and water crude extracts on viability, migratory ability, and the steady-state mRNA levels of genes involved in these processes was, respectively, examined using MTT assay, wound healing assay, and reverse transcriptase PCR (RT-PCR). The study concludes that all extracts significantly reduce human osteosarcoma U2OS percentage viability in a dose- and time-dependent manner, with varying potencies. The least half-maximal inhibitory concentration (IC50) was observed in the water extract after 48 h incubation (30.761±1.4 μg/mL) followed by the ethyl acetate extract after 72 h incubation (80.35±1.233 μg/mL) and finally the ethanol extract after 48 h incubation (97.499±1.188 μg/mL). Ethanol extract significantly reduced U2OS percentage wound closure. On the other hand, both ethanol and water extracts considerably reduced the steady-state mRNA expression of beta-catenin, promoting both cell proliferation and migration in osteosarcoma by regulating target genes. Additionally, E. foeminea showed no hemolytic activity. These effects suggest that E. foeminea decreases U2OS cell viability and migratory ability by modulating the expression of critical genes involved in regulating these processes and is likely cytocompatible with human erythrocytes.

FORCE ON A DROPLET IN ANOTHER LIQUID WITH ARBITRARY ARRANGEMENT OF THE GRAVITY AND THERMAL GRADIENT

2005 ◽  
Vol 19 (28n29) ◽  
pp. 1671-1674
Author(s):  
REN SUN
Keyword(s):  
Gravitational Field ◽  
Steady State ◽  
General Solution ◽  
Physical Properties ◽  
Thermal Gradient ◽  
Droplet Cluster ◽  
And Migration ◽  
State Force

The steady-state force on the droplet released in another liquid subjected to the gravitational field and imposed thermal gradient in the case of vanishingly small Re and Ma is derived using the general solution given by Lamb. A solution to a transitional thermocapillary-type droplet migration is thereby obtained for the case of constant physical properties, which corresponds to the well known YGB result as t → ∞. These can be employed to investigate the interactions between droplets in a host solution under the gravitational and thermal influences, and further to explore deposition and migration of a droplet cluster in the corresponding fields.

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