A highly efficient strategy for the synthesis of 3-substituted salicylic acids by either directed ortho-lithiation or halogenmetal exchange of substituted MOM protected phenols followed by carboxylation.
Keyword(s):
A highly efficient synthesis of various 3-substituted salicylic acids is described starting from inexpensive starting materials and requiring no special apparatus.Key words: salicylic acids, ortho-metalation, halogenmetal exchange, methoxymethyl group.
2001 ◽
Vol 79
(11)
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pp. 1541-1545
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2018 ◽
Vol 16
(30)
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pp. 5533-5538
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2014 ◽
Vol 34
(1)
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pp. 243-250
2013 ◽
Vol 17
(3)
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pp. 283-295
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2011 ◽
Vol 8
(6)
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pp. 385-390
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2011 ◽
Vol 24
(6)
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pp. 745-752
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