CATALASE LEVELS AND RADIOSENSITIVITY OF LIVER CELLS

1960 ◽  
Vol 38 (12) ◽  
pp. 1489-1498 ◽  
Author(s):  
D. K. Myers
Keyword(s):  
Liver Regeneration ◽  
Cell Nucleus ◽  
Liver Cells ◽  
The Other ◽  
Cell Nuclei ◽  
Average Amount ◽  
Normal Value ◽  
Long Period ◽  
Stage Of Development ◽  
High Doses

Following exposure of regenerating liver to 580 r X radiation at a time when the average amount of DNA per cell nucleus has reached 1.6 times the normal value, the usual increase in number of cell nuclei was retarded while the average amount of DNA per cell nucleus continued to rise until it approached twice the normal value. Cell division was delayed for an unusually long period following irradiation at this stage of development. On the other hand, there was no corresponding increase during liver regeneration in the effects of high doses of X radiation on diphosphopyridine nucleotide concentrations in the liver. Although the liver catalase concentration decreased during liver regeneration, inhibition of catalase activity failed to increase the radiosensitivity of liver cells.

CATALASE LEVELS AND RADIOSENSITIVITY OF LIVER CELLS

1960 ◽  
Vol 38 (1) ◽  
pp. 1489-1498 ◽  
Author(s):  
D. K. Myers
Keyword(s):  
Liver Regeneration ◽  
Cell Nucleus ◽  
Liver Cells ◽  
The Other ◽  
Cell Nuclei ◽  
Average Amount ◽  
Normal Value ◽  
Long Period ◽  
Stage Of Development ◽  
High Doses

Following exposure of regenerating liver to 580 r X radiation at a time when the average amount of DNA per cell nucleus has reached 1.6 times the normal value, the usual increase in number of cell nuclei was retarded while the average amount of DNA per cell nucleus continued to rise until it approached twice the normal value. Cell division was delayed for an unusually long period following irradiation at this stage of development. On the other hand, there was no corresponding increase during liver regeneration in the effects of high doses of X radiation on diphosphopyridine nucleotide concentrations in the liver. Although the liver catalase concentration decreased during liver regeneration, inhibition of catalase activity failed to increase the radiosensitivity of liver cells.

The Application of UX Research in New Energy Vehicle Innovation

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Menghan TAO ◽  
Ning XIAO ◽  
Xingfu ZHAO ◽  
Wenbin LIU
Keyword(s):  
Early Stage ◽  
Rapid Expansion ◽  
The Other ◽  
Innovative Product ◽  
Stage Of Development ◽  
New Energy ◽  
New Energy Vehicle ◽  
The One ◽  
New Energy Vehicles ◽  
Degree Of Innovation

New energy vehicles(NEV) as a new thing for sustainable development, in China, on the one hand has faced the rapid expansion of the market; the other hand, for the new NEV users, the current NEVs cannot keep up with the degree of innovation. This paper demonstrates the reasons for the existence of this systematic challenge, and puts forward the method of UX research which is different from the traditional petrol vehicles research in the early stage of development, which studies from the user's essence level, to form the innovative product programs which meet the needs of users and being real attractive.

Effects of caffeine treatment on aged porcine oocytes: parthenogenetic activation ability, chromosome condensation and development to the blastocyst stage after somatic cell nuclear transfer

Zygote ◽  
2005 ◽  
Vol 13 (4) ◽  
pp. 335-345 ◽  
Author(s):  
Masaki Iwamoto ◽  
Akira Onishi ◽  
Dai-ichiro Fuchimoto ◽  
Tamas Somfai ◽  
Shun-ichi Suzuki ◽  
...  
Keyword(s):  
Somatic Cell ◽  
Blastocyst Stage ◽  
The Other ◽  
Control Group ◽  
Blastocyst Formation ◽  
Cell Nuclei ◽  
Somatic Nucleus ◽  
Membrane Breakdown ◽  
Caffeine Treatment ◽  
M Phase

The possibility of using aged porcine oocytes treated with caffeine, which inhibits the decrease in M-phase promoting factor activity, for pig cloning was evaluated. Cumulus–oocyte complexes (COCs) were cultured initially for 36h and subsequently with or without 5mM caffeine for 24h (in total for 60h: 60CA+ or 60CA– group, respectively). As a control group, COCs were cultured for 48h without caffeine (48CA–). The pronuclear formation rates at 10h after electrical stimulation in the 60CA+ and 60CA– groups decreased significantly (p<0.05) compared with the 48CA– group. However, the fragmentation rate was significantly higher (p<0.05) in the 60CA– group than in the 60CA+ and 48CA– groups. When the stimulated oocytes were cultured for 6 days, the 60CA+ group showed significantly lower blastocyst formation and higher fragmentation or degeneration rates (p<0.05) than the 48CA– group. However, the number of total cells in blastocysts was not affected by maturation period or caffeine treatment. When somatic cell nuclei were injected into the non-enucleated oocytes and exposed to cytoplasm for a certain duration (1–11h) before the completion of maturation (48 or 60h), the rate of nuclear membrane breakdown after exposure to cytoplasm for 1–2h in the 60CA– oocytes was significantly lower (p;<0.05) than in the other experimental groups. The rate of scattered chromosome formation in the same 60CA– group tended to be lower (p=0.08) than in the other groups. After the enucleation and transfer of nuclei, blastocyst formation rates in the 60CA+ and 60CA– groups were significantly lower (p<0.05) than in the 48CA– group. Blastocyst quality did not differ among all the groups. These results suggest that chromosome decondensation of the transplanted somatic nucleus is affected by both the duration of exposure to cytoplasm and the age of the recipient porcine oocytes, and that caffeine treatment promotes nuclear remodelling but does not prevent the decrease in the developmental ability of cloned embryos caused by oocyte aging.

Anniversary Address

1986 ◽  
Vol 66 (1) ◽  
pp. 1-8 ◽  
Author(s):  
John D. Evans
Keyword(s):  
The Other ◽  
Average Amount ◽  
Strong Body ◽  
Do So

The other day I received a letter from someone I did not know, but who shares my rather common surname. This gentleman had received a piece of mail intended for me—a Who's Who entry for correction, in fact. The occurrence in itself was not very remarkable, as those of you who have surnames which are as widely distributed as mine will especially appreciate. What was particularly striking to me was that my correspondent began his letter by saying that he had never written to an archaeologist before, and could not resist the temptationto do so now. I replied that I was somewhat surprised that archaeologists could still have such a curiosity value; it had been my impression that we had become so relatively common during the last two decades as not to attract much more notice than many other professions. We are still not, and are never likely to be, a large profession, but there is also, of course, a strong body of serious amateurs who can also reasonably call themselves qualified archaeologists—and we do get a more than average amount of publicity.

Voices of Spectators and Audience Power

Pólemos ◽  
2015 ◽  
Vol 9 (2) ◽  
Author(s):  
Christian Biet
Keyword(s):  
Social Relationship ◽  
The Other ◽  
Long Period ◽  
The Social ◽  
The Common ◽  
Dramatic Action ◽  
The Law ◽  
The Voice ◽  
The Way

AbstractTheatre and law are not so different. Generally, researchers work on the art of theatre, the rhetoric of the actors, or the dramaturgy built from law cases or from the questions that the law does not completely resolve. Trials, tragedies, even comedies are close: everybody can see the interpenetration of them on stage and in the courts. We know that, and we know that the dramas are made with/from/of law, we know that the art the actors are developing is not so far from the art of the lawyers, and conversely. In this paper, I would like to have a look at the action of the audience, at the session itself and at the way the spectators are here to evaluate and judge not only the dramatic action, not only the art of the actors, not only the text of the author, but also the other spectators, and themselves too. In particular, I will focus on the “common judgment” of the audience and on its judicial, aesthetic and social relationship. The spectators have been undisciplined, noisy, unruled, during such a long period that theatre still retains some prints of this behaviour, even if nowadays, the social and aesthetic rule is to be silent. But uncertainty, inattention, distraction, contradiction, heterogeneity are the notions which characterise the session, and the judgments of the spectators still depend on them. So, what was and what is the voice of the audience? And with what sort of voice do spectators give their judgments?

scholarly journals Job Satisfaction and Employee Engagement Contemporary Tools to Eliminate Stress Among work Force in an Organization

2019 ◽  
Vol 8 (6) ◽  
pp. 2381-2383
Keyword(s):  
Job Satisfaction ◽  
Employee Engagement ◽  
Positive Attitude ◽  
Employee Performance ◽  
Work Force ◽  
The Other ◽  
Negative Behavior ◽  
Fundamental Factor ◽  
Long Period ◽  
Utmost Care

Stress is a not a new word to the organizations. It is been a boiling subject from years ago as it is spread across the globe. To evade this, organizations tries to improve their employee’s satisfaction levels at job, so that a positive attitude can be inculcated among workforce. The other tool to abstain from mocking execution and deriding performance of an organization is employee’s engagement. It is a key which prompts hierarchical achievement and furthermore a fundamental factor to be considered while assessing stress. Stress cannot be eliminated from any organization but can be handled with utmost care to get good results. If stress is not managed well, it generates a negative behavior in workforce which destroys the end results or an organization fails to achieve its goals. If it continues for a long period of time, the result could be closure of an organization because over stress will reduce the employee performance. This research paper is expected to comprehend the reasons which lead to employee stress inside an organization, to discuss the variables which robustly correlate with stress level of employees and also to suggest the mechanism to overcome stress.

scholarly journals Study of pathological lesions in rats after the experimental administration of Lindane

2018 ◽  
Vol 49 (1) ◽  
pp. 39
Author(s):  
N. PAPAIOANNOU (Ν. ΠΑΠΑΪΩΑΝΝΟΥ) ◽  
G. KELLER-SAMOUILIDOU (ΓΚ. ΚΕΛΛΕΡ-ΣΑΜΟΥΗΛΙΔΟΥ) ◽  
S. LEKKAS (Σ. ΛΕΚΚΑΣ) ◽  
V. P. KOTSAKI-KOVATSI (Β. Π. ΚΩΤΣΑΚΗ-ΚΟΒΑΤΣΗ) ◽  
A. KOVATSI (Α. ΚΟΒΑΤΣΗΣ)
Keyword(s):  
Clinical Symptoms ◽  
Chemical Substance ◽  
The Other ◽  
Coagulative Necrosis ◽  
Cardiac Muscle Cells ◽  
Experimental Animals ◽  
Long Period ◽  
Hepatic Cells ◽  
Cross Striation ◽  
The Brain

In this experimental study, the lesions that are caused from the chemical substance Lindane were studied. Sixteen rats were used as experimental animals. The substance was orally administered, with food, to 10 rats (5 females and 5 males) in a dose of 8,2 mg/kg b.w./3 days during the first 10 days and in a dose of the 33 mg/kg b.w./ 2 days during the following 40 days. The remaining 6 rats (4 females and 2 males) were used as controls. The mainly clinical symptoms which were observed in the experimental animals, in the end of the experimentation, were anorexia, lethargy, hypothermia and muscular rigor. All the rats were sacrificed 5 days after the administration of the last dose of the substance and they were autopsied. In the macroscopical examination oedema and vascular hyperhaemia were observed in the brain. In the histological examination spongiosis of the white matter of the brain, interstitial pneumonia, oedema and loss of the cross striation of the cardiac muscle cells, coagulative necrosis of individual groups of hepatic cells and degeneration of the epithelial cells of the urinary tubules were detected. In conclusion, when Lindane is administered in subtoxical doses for a long period of time it is possible to cause damages to the organism of the experimental animals, which are located mainly in the brain and secondary in the liver, the kidneys and the other organs.

Twintig jaar politieke strijd rond de abortuswetgeving in België (1970-1990)

Res Publica ◽  
1990 ◽  
Vol 32 (4) ◽  
pp. 427-487
Author(s):  
Els Witte
Keyword(s):  
The Other ◽  
Political Crisis ◽  
Pressure Groups ◽  
Abortion Law ◽  
Long Period ◽  
The Law ◽  
The One

Tbe struggle for the liberalization of the law on abortion began in Belgium in 1970 when the taboo was breached in an initial bill. However, support by pressure groups failed and this led to a long period of nondecision, which may be explained by the disunity in the camp of the supporters on the one hand and the blocking tactics of the Flemish Christian Democrats on the other. In 1986 a compromise between supporters finally emerged, and via a majority which cut right through the governmental coalition an abortion law was approved at the end of March 1990, which closely corresponds to British, French and Dutch legislation.  The catholic monarch's refusal to ratify the bill caused a political crisis which was solved by the unanimous signing by the assembled ministers.

«Liberdades e Direitos» No Horizonte da Soberania

2000 ◽  
Vol 8 (15) ◽  
pp. 151-175
Author(s):  
Viriato Soromenho-Marques ◽  
Keyword(s):  
Civil War ◽  
French Revolution ◽  
Common Ground ◽  
The Other ◽  
English Civil War ◽  
Reciprocal Influence ◽  
Political Tradition ◽  
Long Period ◽  
The Common ◽  
Relationship Of

The common ground and dissimilarities in the reciprocal influence between two apparently identical concepts in the Contemporary western political tradition - freedom and liberty - are dealt in this paper. The author tries to tackle the interrelated genealogy both of freedom and liberty categories, in the long period opened by the English Civil War and closed by the conflicting reactions to the French Revolution. The sovereignty concept on the other hand allows the reader to understand the ongoing dynamic of the crucial philosophical relationship of these two central concepts.

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