EFFECTS OF VARYING PROPORTIONS OF DIETARY RAPESEED OIL ON THE RAT

1957 ◽  
Vol 35 (12) ◽  
pp. 1225-1231 ◽  
Author(s):  
Joyce L. Beare ◽  
T. K. Murray ◽  
J. A. Campbell
Keyword(s):  
Body Weight ◽  
Rapeseed Oil ◽  
Corn Oil ◽  
Liver Weight ◽  
Male Rats ◽  
Weanling Rats ◽  
Total Diet ◽  
Weight Gains ◽  
Lipid Excretion

Rapeseed oil, corn oil, and mixtures of the two oils containing 5, 10, 20, 40, and 80% rapeseed oil were fed to weanling rats at levels of 10 and 20% by weight of the purified diet. A significant decrease in body weight gains and in food consumptions occurred with the two highest levels of rapeseed oil, that is, 16 and 20% by weight of the total diet. At the same levels there was an increased lipid excretion. Corn oil and rapeseed oil which had been heated to 200 °C. for 120 hours produced no changes in weight gains when fed at the 10% level, but exhibited some growth-retarding effects at the 20% level. At both levels heated corn oil and rapeseed oil increased the liver weight of male rats.

EFFECTS OF VARYING PROPORTIONS OF DIETARY RAPESEED OIL ON THE RAT

1957 ◽  
Vol 35 (1) ◽  
pp. 1225-1231 ◽  
Author(s):  
Joyce L. Beare ◽  
T. K. Murray ◽  
J. A. Campbell
Keyword(s):  
Body Weight ◽  
Rapeseed Oil ◽  
Corn Oil ◽  
Liver Weight ◽  
Male Rats ◽  
Weanling Rats ◽  
Total Diet ◽  
Weight Gains ◽  
Lipid Excretion

Rapeseed oil, corn oil, and mixtures of the two oils containing 5, 10, 20, 40, and 80% rapeseed oil were fed to weanling rats at levels of 10 and 20% by weight of the purified diet. A significant decrease in body weight gains and in food consumptions occurred with the two highest levels of rapeseed oil, that is, 16 and 20% by weight of the total diet. At the same levels there was an increased lipid excretion. Corn oil and rapeseed oil which had been heated to 200 °C. for 120 hours produced no changes in weight gains when fed at the 10% level, but exhibited some growth-retarding effects at the 20% level. At both levels heated corn oil and rapeseed oil increased the liver weight of male rats.

THE EFFECTS OF DIFFERENT VARIETIES OF RAPESEED OIL ON WEIGHT GAIN, AND OF GOLDEN RAPESEED OIL ON REPRODUCTION, OF THE RAT

1959 ◽  
Vol 37 (10) ◽  
pp. 1191-1195 ◽  
Author(s):  
Joyce L. Beare ◽  
E. R. W. Gregory ◽  
J. A. Campbell
Keyword(s):  
Weight Gain ◽  
Erucic Acid ◽  
Rapeseed Oil ◽  
Corn Oil ◽  
Retarding Effect ◽  
Wistar Strain ◽  
Weanling Rats ◽  
Weight Gains ◽  
Reproduction Study

Rapeseed oil of the Polish, Golden, or Swedish varieties, corn oil, or mixtures of corn oil and ethyl erucate were fed to weanling rats of the Wistar strain for 9 weeks. Weight gains were inversely related to the content of erucic acid in the diet, confirming previous indications that the growth retarding effect of rapeseed oil is due to its erucic acid. In general, the differences in weight gains could be explained by the effect of rapeseed oil on food consumption.Golden rapeseed oil and corn oil were compared in a reproduction study involving three litters of one generation. Although the young of rats fed rapeseed oil were of lesser weanling weight, there was no difference in the number of animals successfully weaned.

A COMPARISON OF THE UTILIZATION OF RAPESEED OIL AND CORN OIL BY THE RAT

1959 ◽  
Vol 37 (5) ◽  
pp. 613-621 ◽  
Author(s):  
Joyce L. Beare ◽  
T. K. Murray ◽  
H. C. Grice ◽  
J. A. Campbell
Keyword(s):  
Body Weight ◽  
Vitamin A ◽  
Rapeseed Oil ◽  
Wistar Rats ◽  
Corn Oil ◽  
Weekly Interval ◽  
Organ Weights ◽  
Weight Gains ◽  
Ad Libitum ◽  
Liver Storage

The effects of Golden rapeseed oil and corn oil on weekly weight gains, food consumptions, liver storage of vitamin A, plasma and adrenal cholesterol concentrations, organ weights, and testes histology were determined in Wistar rats for 5 weeks after weaning. At each weekly interval, animals fed rapeseed oil showed lesser weight gains and food consumptions, but, when body weight gains were adjusted for food consumptions by covariance analyses, differences largely disappeared. Liver storage of vitamin A was similar with both oils. Testes of animals fed rapeseed oil exhibited no alteration in cellular characteristics, but a reduction in tubular size. When fed to older rats, rapeseed oil again produced smaller weight gains which were accounted for at 4 weeks' time by a depressed appetite.Similar weight gains were obtained with corn oil and rapeseed oil when the oils were paired fed and when adjustments for food consumption were made by covariance analyses of weight gains of animals receiving the oils ad libitum. With corn oil supplied on a restricted basis the testicular tubules were smaller than those obtained with unrestricted feeding of corn oil. The absorption of corn oil and rapeseed oil fed ad libitum was 95 and 92% respectively. It was concluded that the two oils were not very differently utilized.

THE EFFECTS OF DIFFERENT VARIETIES OF RAPESEED OIL ON WEIGHT GAIN, AND OF GOLDEN RAPESEED OIL ON REPRODUCTION, OF THE RAT

1959 ◽  
Vol 37 (1) ◽  
pp. 1191-1195 ◽  
Author(s):  
Joyce L. Beare ◽  
E. R. W. Gregory ◽  
J. A. Campbell
Keyword(s):  
Weight Gain ◽  
Erucic Acid ◽  
Rapeseed Oil ◽  
Corn Oil ◽  
Retarding Effect ◽  
Wistar Strain ◽  
Weanling Rats ◽  
Weight Gains ◽  
Reproduction Study

Rapeseed oil of the Polish, Golden, or Swedish varieties, corn oil, or mixtures of corn oil and ethyl erucate were fed to weanling rats of the Wistar strain for 9 weeks. Weight gains were inversely related to the content of erucic acid in the diet, confirming previous indications that the growth retarding effect of rapeseed oil is due to its erucic acid. In general, the differences in weight gains could be explained by the effect of rapeseed oil on food consumption.Golden rapeseed oil and corn oil were compared in a reproduction study involving three litters of one generation. Although the young of rats fed rapeseed oil were of lesser weanling weight, there was no difference in the number of animals successfully weaned.

A COMPARISON OF THE UTILIZATION OF RAPESEED OIL AND CORN OIL BY THE RAT

1959 ◽  
Vol 37 (1) ◽  
pp. 613-621 ◽  
Author(s):  
Joyce L. Beare ◽  
T. K. Murray ◽  
H. C. Grice ◽  
J. A. Campbell
Keyword(s):  
Body Weight ◽  
Vitamin A ◽  
Rapeseed Oil ◽  
Wistar Rats ◽  
Corn Oil ◽  
Weekly Interval ◽  
Organ Weights ◽  
Weight Gains ◽  
Ad Libitum ◽  
Liver Storage

The effects of Golden rapeseed oil and corn oil on weekly weight gains, food consumptions, liver storage of vitamin A, plasma and adrenal cholesterol concentrations, organ weights, and testes histology were determined in Wistar rats for 5 weeks after weaning. At each weekly interval, animals fed rapeseed oil showed lesser weight gains and food consumptions, but, when body weight gains were adjusted for food consumptions by covariance analyses, differences largely disappeared. Liver storage of vitamin A was similar with both oils. Testes of animals fed rapeseed oil exhibited no alteration in cellular characteristics, but a reduction in tubular size. When fed to older rats, rapeseed oil again produced smaller weight gains which were accounted for at 4 weeks' time by a depressed appetite.Similar weight gains were obtained with corn oil and rapeseed oil when the oils were paired fed and when adjustments for food consumption were made by covariance analyses of weight gains of animals receiving the oils ad libitum. With corn oil supplied on a restricted basis the testicular tubules were smaller than those obtained with unrestricted feeding of corn oil. The absorption of corn oil and rapeseed oil fed ad libitum was 95 and 92% respectively. It was concluded that the two oils were not very differently utilized.

EFFECTS OF SATURATED FAT IN RATS FED RAPESEED OIL

1963 ◽  
Vol 41 (1) ◽  
pp. 605-612 ◽  
Author(s):  
Joyce L. Beare ◽  
J. A. Campbell ◽  
C. G. Youngs ◽  
B. M. Craig
Keyword(s):  
Fatty Acids ◽  
Erucic Acid ◽  
Palmitic Acid ◽  
Rapeseed Oil ◽  
Unsaturated Fatty Acids ◽  
Corn Oil ◽  
Methyl Esters ◽  
Saturated Fatty Acids ◽  
Weight Gains ◽  
Similar Content

The effects of increasing the saturated fatty acids in a dietary vegetable oil composed mostly of unsaturated fatty acids were studied in rats. A mixture of palm oil and Swedish rapeseed oil fed for 4 weeks as 20% of a purified diet promoted weight gains which exceeded those obtained with Polish rapeseed oil of a similar content of erucic acid, and altered the proportion of saturated fatty acids in the tissues to reflect that of the diet. When methyl esters of saturated fatty acids were added to Swedish rapeseed oil, similar effects on weight gain were not observed, but methyl esters of fatty acids from corn oil and rapeseed oil were shown to be of less nutritional value than the original glycerides. From fatty acids of olive oil, glycerides containing 3% palmitic acid were prepared, and produced weight gains which did not differ significantly from those of rats fed Polish rapeseed oil with a similar content of palmitic acid and 20% erucic acid. The characteristic effects of rapeseed oil are, therefore, attributed to its low content of saturated fatty acids as well as its high content of erucic acid.

Reproductive Toxicity Study of Clarified Slurry Oil in the Rat

1995 ◽  
Vol 14 (2) ◽  
pp. 119-128 ◽  
Author(s):  
A. M. Hoberman ◽  
M. S. Christian ◽  
R. Roth ◽  
S. Lovre ◽  
F. Koschier
Keyword(s):  
Body Weight ◽  
Reproductive Toxicity ◽  
Reproductive Organ ◽  
Female Rats ◽  
Male Rats ◽  
Feed Consumption ◽  
Clinical Effects ◽  
Weight Losses ◽  
Male And Female Rats ◽  
Weight Gains

Clarified slurry oil (CSO, CAS #64741–62-4; also termed carbon black oil), a residual product from the fluidized catalytic cracker in petroleum refining, has the potential to be absorbed through the skin. The reproductive toxicity of CSO in male and female rats was evaluated by the topical route of exposure. CSO was administered dermally to male rats at dosages of 0 (vehicle), 0.1, 1, 10, 50, and 250 mg/kg/day for 70 days before a cohabitation period with untreated female rats. CSO was administered also to female rats at the same dosages for 14 days prior to a 7-day cohabitation period and continuing until Day 0 of gestation (day spermatozoa was present in a smear of the vaginal contents or a copulatory plug was observed in situ). The dosage volume in both experiments was 1 ml/kg, adjusted on each day of dosage based on individual body weights recorded immediately before application of CSO. Under the conditions of these experiments, the paternal no-observable-adverse-effect-level (NOAEL) for CSO administered dermally was 1 mg/kg/day. The 10, 50, and 250 mg/kg/day dosages of CSO caused body weight losses and/or decreased body weight gains and reduced feed consumption. The 50- and 250-mg/kg/day dosages also caused adverse clinical effects. No mating, fertility, or testicular end points in male rats were affected by the highest dosages tested; therefore, the reproductive NOAEL for male rats is <250 mg/kg/day. The maternal NOAEL for CSO administered dermally was 10 mg/kg/day. The 50-and 250-mg/kg/day dosages of CSO reduced body weight gains; 250 mg/kg/day also reduced feed consumption. There were no adverse effects on gonadal function, estrous cycles, mating behavior, conception rates, or reproductive organ weights; therefore, the reproductive NOAEL for female rats administered CSO dermally is at least 250 mg/kg/day.

THE DETERMINATION OF THE AVAILABLE CALORIC CONTENT OF RAPESEED OIL BY RAT GROWTH

1958 ◽  
Vol 36 (1) ◽  
pp. 203-208 ◽  
Author(s):  
E. J. Middleton ◽  
J. A. Campbell
Keyword(s):  
Rapeseed Oil ◽  
Corn Oil ◽  
Metabolic Energy ◽  
Caloric Content ◽  
Growth Responses ◽  
Weight Growth ◽  
Weanling Rats ◽  
Significant Difference ◽  
Rat Growth

The available metabolic energy of rapeseed oil, semihydrogenated rapeseed oil, and corn oil was measured in terms of 7-day body-weight gains of weanling rats fed a calorically restricted diet. Standard bio-assay procedures were used with lard as a reference standard. The oils were fed at three levels equivalent to 5, 9, and 17% of the diet by weight. Growth responses to the three oils and to lard were similar and the calculated caloric content of the oils showed no significant difference from that of lard. A 1 week assay was as precise as a 5 week assay.

Electrocardiograms of male rats fed rapeseed oil

1977 ◽  
Vol 55 (5) ◽  
pp. 1116-1121 ◽  
Author(s):  
W. G. Hunsaker ◽  
H. W. Hulan ◽  
J. K. G. Kramer ◽  
A. H. Corner
Keyword(s):  
Rapeseed Oil ◽  
Corn Oil ◽  
Frontal Plane ◽  
P Wave ◽  
Male Rats ◽  
Qrs Complex ◽  
Sprague Dawley ◽  
Cardiac Rate ◽  
Sprague Dawley Rats ◽  
Wave Forms

Frontal plane electrocardiograms (standard limb leads) were recorded on male Sprague–Dawley rats fed for 14 weeks on semisynthetic diets containing 20% (by weight) of Brassica napus cv. Tower or B. campestris cv. Span rapeseed oil or fractions isolated from Span rapeseed oil. Control diets were rat Chow or semisynthetic diets containing 20% (by weight) of either safflower oil or corn oil. The amplitude of the P, Q, R, S, and T waves, the duration of the P wave, QRS complex, and P–R interval, and the cardiac rate were measured in the electrocardiograms and differences between groups compared statistically. While there were statistically significant differences in the amplitude of some of the wave forms, there were no consistent differences which could be attributed to the feeding of rapeseed oil or its fractions. The duration of the P wave and the QRS complex were significantly longer in some of the control groups than those in most of the treated groups. There was no correlation between the presence of a Q wave and the incidence of myocardial lesions in any group. Cardiac rate was essentially the same in all groups.

scholarly journals Effects ofNigella sativa(Habbatus sauda) Oil and Nicotine Chronic Treatments on Sperm Parameters and Testis Histological Features of Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Ng Cho Ping ◽  
Noor Hashida Hashim ◽  
Durriyyah Sharifah Hasan Adli
Keyword(s):  
Body Weight ◽  
Sperm Motility ◽  
Seminiferous Tubule ◽  
Corn Oil ◽  
Sperm Quality ◽  
Sperm Parameters ◽  
Male Rats ◽  
Seminiferous Tubules ◽  
Sprague Dawley ◽  
Histological Features

Twenty-fourSprague-Dawleymale rats (7–9 weeks old, 200–250 g) were divided into Nicotine (N) (0.5 mg/100 g body weight (BW), Nicotine Control (NC) (saline, 0.1 mL/100 g BW),Habbatus saudaoil (HS) (6.0 μL/100 g BW), andHabbatus saudaControl (HSC) (corn oil, 0.1 mL/100 g BW) groups and treated for 100 days. Sperm parameters and seminiferous tubules measurements were evaluated. The N showed a significantly lower sperm motility (1.03±0.05×106 sperm/mL) and percentage of normal (82.61±0.03%) and live (93.88±0.01%) sperm, higher value for the seminiferous tubule (253.36±1.83 μm) and lumen (100.15±2.38 μm) diameters and spermatogonia (19.85±0.39 μm) and spermatocytes (33.37±0.59 μm) layers, and thinner spermatid-sperm layer (22.14±0.71 μm) than the NC (P<0.05). The HS had significantly higher sperm motility (1.49±0.04×106 sperm/mL) and percentage of normal (90.61±0.01%) and live (96.98±0.01%) sperm, smaller lumen diameter (67.53±2.34 μm) and thinner spermatogonia (17.67±0.32 μm) and wider spermatid-sperm (36.95±0.79 μm) layers than the HSC (P<0.05). This research confirmed that nicotine reduced sperm motility and morphology of normal and live sperms and also affected the testis histology, whileHabbatus saudaoil increased sperm quality and gave better testis histological features.

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