An internal blast analysis of a steel box memberThis article is one of a selection of papers published in the Special Issue on Blast Engineering.

2009 ◽  
Vol 36 (8) ◽  
pp. 1332-1339 ◽  
Author(s):  
Wai Tak Wong
Keyword(s):  
Finite Element ◽  
Response Analysis ◽  
Special Issue ◽  
Modeling Methods ◽  
Prediction Tools ◽  
Blast Effects ◽  
Unique Approach ◽  
Computer Codes ◽  
Confined Environment ◽  
Selection Of

This paper presents a unique approach that can be used for the analysis of a blast due to an internal detonation. The information in this paper focuses on understanding the blast effects in a confined environment, blast loads prediction, and response analysis using computer codes and finite element modeling methods. An example is included in which a partial segment of a steel box member is analyzed for its response to an internal blast using blast prediction tools and finite element code.

Risk assessment of buildings against blast effectsThis article is one of a selection of papers published in the Special Issue on Blast Engineering.

2009 ◽  
Vol 36 (8) ◽  
pp. 1285-1291 ◽  
Author(s):  
Simon Foo ◽  
Bert von Rosen ◽  
Ettore Contestabile
Keyword(s):  
Risk Assessment ◽  
Security Requirements ◽  
Rapid Screening ◽  
Existing Buildings ◽  
Blast Loads ◽  
Special Issue ◽  
Preliminary Assessment ◽  
Blast Effects ◽  
New Buildings ◽  
Selection Of

Because of changes in functional or security requirements, many new or existing buildings are now required to resist blast loads. New buildings can be designed and constructed to resist defined blast loads. Existing buildings, on the other hand, would have to rely on a risk assessment to determine both its vulnerability to blast effects and the necessary measures to mitigate the unacceptable blast effects. A rapid screening methodology has been developed for conducting a preliminary assessment of buildings against external blast effects. The methodology accounts for the threat, the vulnerability of the building, the consequence of an event and the risk, which is the product of the threat and the consequence. The rapid screening methodology has been applied to several buildings and the results are reasonable. This paper presents the rapid screening methodology and its application to two federal buildings in Canada.

Introduction: Affixes and bases

2011 ◽  
Vol 4 (2) ◽  
pp. 161-168
Author(s):  
Stela Manova
Keyword(s):  
Special Issue ◽  
Affix Order ◽  
Selection Of ◽  
Affix Ordering

This special issue includes a selection of papers presented at the 2nd Vienna Workshop on Affix Order held in Vienna, Austria on June 4–5, 2009. The workshop was in honor of Wolfgang U. Dressler on the occasion of his 70th birthday. However, this special issue differs from the classical Festschrift dedicated to a renowned scholar and is ‘more special’ in two respects at least: 1) not all authors are Dressler's friends and colleagues, some of them are only indirectly related to him, through his students; and 2) since the papers were presented at a topic-oriented workshop, they are thematically uniform. In other words, this special issue is a kind of scientific genealogy in terms of affix ordering. Thus, the title Affixes and bases should be understood in two ways: literally – affixes and bases as linguistic notions, and metaphorically – affixes and bases as linguists related directly and indirectly to a prominent base: Wolfgang U. Dressler.

FEATURES OF ORGANOPHOSPHATES IMMOBILIZATION VIA STREPTAVIDIN-BIOTIN SYSTEM FOR EXPERIMENTS ON SELECTION OF APTAMERS

2020 ◽  
pp. 12-20
Author(s):  
D. A. Belinskaya ◽  
Yu. V. Chelusnova ◽  
V. V. Abzianidze ◽  
N. V. Goncharov
Keyword(s):  
Polyethylene Glycol ◽  
Organophosphorus Compounds ◽  
Binding Energies ◽  
Rna Aptamers ◽  
Main Method ◽  
Modeling Methods ◽  
Molecular Dynamics Methods ◽  
Systematic Evolution ◽  
Exponential Enrichment ◽  
Selection Of

Poisoning with organophosphorus compounds occupy one of the leading places in exotoxicosis. At the first stage, the detoxification of organophosphates can be provided with the help of DNA or RNA aptamers that bind the poison in the bloodstream. Currently, the main method of searching for aptamers is the experimental method of systematic evolution of ligands by exponential enrichment (SELEX). In the process of aptamer selection, the target molecule must be immobilized via the streptavidin-biotin complex. Since the poison molecule is small in size, to increase its availability for binding to aptamer, it is necessary to use a spacer between organophosphorus compounds and biotin. The aim of this work was to optimize the selection of aptamers for organophosphorus compounds by increasing the availability of a poison molecule immobilized via the streptavidin-biotin complex on the example of paraoxon. For this purpose, three spacers between organophosphorus compounds and biotin were tested using molecular modeling methods: three links of polyethylene glycol (3-PEG), four links of polyethylene glycol (4-PEG) and aminohexyl. The conformation of the biotinylated paraoxon complex with streptavidin and the interaction of paraoxon with the binding fragment of the aptamer were modeled using molecular docking and molecular dynamics methods. The ability of biotinylated paraoxon to bind to the aptamer has been evaluated by analyzing the surface area of the paraoxon available to the solvent, as well as by calculating the free binding energies. It has been shown that only in the case of aminohexyl immobilized paraoxon can contact the aptamer. At the final stage, the synthesis of paraoxon bound to biotin via aminohexyl was carried out.

tti2002: Introduction and Conference Overview

2003 ◽  
Vol 17 (1) ◽  
pp. 9-14 ◽  
Author(s):  
E. H. Robson
Keyword(s):  
Higher Education ◽  
Technology Transfer ◽  
Special Issue ◽  
International Convention ◽  
International Conference ◽  
Introductory Paper ◽  
Personal Reflections ◽  
Selection Of

This special issue of Industry and Higher Education is devoted to a selection of papers and reports from tti2002, an international conference on technology transfer and innovation held at the International Convention Centre, Birmingham, UK in July 2002. In this introductory paper, the author provides the context of the conference, summarizes the presentations given by invited speakers and offers personal reflections on the event.

scholarly journals Recent Advances in Kinase Drug Discovery Part I: The Editors’ Take

2021 ◽  
Vol 22 (14) ◽  
pp. 7560
Author(s):  
Julie A. Tucker ◽  
Mathew P. Martin
Keyword(s):  
Drug Discovery ◽  
Research Articles ◽  
Special Issue ◽  
Recent Advances ◽  
Enzyme Family ◽  
Selection Of

This special issue on Advances in Kinase Drug Discovery provides a selection of research articles and topical reviews covering all aspects of drug discovery targeting the phosphotransferase enzyme family [...]

scholarly journals Exposure and Health Impacts Related to Outdoor and Indoor Air Pollutants

Atmosphere ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 105
Author(s):  
Haider A. Khwaja
Keyword(s):  
Indoor Air ◽  
Air Pollutants ◽  
Health Impacts ◽  
Special Issue ◽  
Indoor Air Pollutants ◽  
Selection Of

The five papers included in this Special Issue represent a diverse selection of contributions [...]

Romance and Latin approaches to word structure features

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Elisabeth Gibert-Sotelo ◽  
Isabel Pujol Payet
Keyword(s):  
The Other ◽  
Special Issue ◽  
Valuable Contribution ◽  
Field Of Study ◽  
Word Structure ◽  
New Approaches ◽  
Theoretical Approaches ◽  
Special Collection ◽  
Introductory Paper ◽  
Selection Of

Abstract The interest in morphology and its interaction with the other grammatical components has increased in the last twenty years, with new approaches coming into stage so as to get more accurate analyses of the processes involved in morphological construal. This special issue is a valuable contribution to this field of study. It gathers a selection of five papers from the Morphology and Syntax workshop (University of Girona, July 2017) which, on the basis of Romance and Latin phenomena, discuss word structure and its decomposition into hierarchies of features. Even though the papers share a compositional view of lexical items, they adopt different formal theoretical approaches to the lexicon-syntax interface, thus showing the benefit of bearing in mind the possibilities that each framework provides. This introductory paper serves as a guide for the readers of this special collection and offers an overview of the topics dealt in each contribution.

scholarly journals Special Issue “Applications of Finite Element Modeling for Mechanical and Mechatronic Systems”

2021 ◽  
Vol 11 (11) ◽  
pp. 5170
Author(s):  
Marek Krawczuk ◽  
Magdalena Palacz
Keyword(s):  
Finite Element Method ◽  
Finite Element ◽  
Numerical Modeling ◽  
Engineering Practice ◽  
The Finite Element Method ◽  
Special Issue ◽  
Mechatronic Systems ◽  
Modeling And Analysis ◽  
Modern Engineering ◽  
Concise Description

Modern engineering practice requires advanced numerical modeling because, among other things, it reduces the costs associated with prototyping or predicting the occurrence of potentially dangerous situations during operation in certain defined conditions. Different methods have so far been used to implement the real structure into the numerical version. The most popular have been variations of the finite element method (FEM). The aim of this Special Issue has been to familiarize the reader with the latest applications of the FEM for the modeling and analysis of diverse mechanical problems. Authors are encouraged to provide a concise description of the specific application or a potential application of the Special Issue.

scholarly journals Special Issue: “Advances in Structural Mechanics Modeled with FEM”

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 780
Author(s):  
Angelo Marcello Tarantino ◽  
Carmelo Majorana ◽  
Raimondo Luciano ◽  
Michele Bacciocchi
Keyword(s):  
Finite Element Method ◽  
Finite Element ◽  
Structural Mechanics ◽  
The Finite Element Method ◽  
Special Issue ◽  
Numerical Investigations ◽  
Current Special Issue ◽  
Element Method

The current Special Issue entitled “Advances in Structural Mechanics Modeled with FEM” aims to collect several numerical investigations and analyses focused on the use of the Finite Element Method (FEM) [...]

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