Hormonal Responses of Multiset Versus Single-Set Heavy-Resistance Exercise Protocols

1997 ◽  
Vol 22 (3) ◽  
pp. 244-255 ◽  
Author(s):  
Lincoln Allan Gotshalk ◽  
Chad C Loebel ◽  
Bradley C Nindl ◽  
Margot Putukian ◽  
Wayne J Sebastianelli ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Resistance Exercise ◽  
Recovery Phase ◽  
Serum Growth Hormone ◽  
Hormonal Responses ◽  
Anabolic Hormones ◽  
Key Words Growth ◽  
Heavy Resistance Exercise ◽  
Key Words Growth Hormone ◽  
Single Set

The purpose of this study was to compare serum growth hormone (GH), testosterone (T), cortisol (C) and whole blood lactate (L) responses to single set (1S) versus multiple set (3S) heavy-resistance exercise protocols. Eight recreationally weight-trained men completed two identical resistance exercise workouts (1S vs. 3S). Blood was obtained prexcerise (PRE), immediately postexercise (0P), and 5 min (5P), 15 min (15P), 30 min and 60 min (60P) postexercise and was analyzed for GH, T, C, and L levels. For 1S and 3S, GH, L, and T significantly increased from PRE to 0P and remained significantly elevated to 60P, except for 1S. For GH, T, and L, 3S showed significantly greater increases compared to 1S. For C, 3S and 1S were increased significantly from resting at 0P, 5P, and 15P; 3S increased compared to 1S at 5P, 15P and 30P. Higher volumes of total work produce significantly greater increases in circulating anabolic hormones during the recovery phase following exercise. Key words: growth hormone, testosterone, cortisol, lactate, strength

Hormonal responses to consecutive days of heavy-resistance exercise with or without nutritional supplementation

1998 ◽  
Vol 85 (4) ◽  
pp. 1544-1555 ◽  
Author(s):  
William J. Kraemer ◽  
Jeff S. Volek ◽  
Jill A. Bush ◽  
Margot Putukian ◽  
Wayne J. Sebastianelli
Keyword(s):  
Growth Hormone ◽  
Growth Factor ◽  
Resistance Exercise ◽  
Crossover Design ◽  
Hormonal Responses ◽  
Carbohydrate Supplementation ◽  
Factor I ◽  
Before And After ◽  
Heavy Resistance Exercise ◽  
Carbohydrate Supplement

Nine resistance-trained men consumed either a protein-carbohydrate supplement or placebo for 1 wk in a crossover design separated by 7 days. The last 3 days of each treatment, subjects performed resistance exercise. The supplement was consumed 2 h before and immediately after the workout, and blood was obtained before and after exercise (0, 15, 30, 45, and 60 min postexercise). Lactate, growth hormone, and testosterone were significantly ( P ≤ 0.05) elevated immediately postexercise. The lactate response was significantly lower during supplementation on days 2 and 3. Growth hormone and prolactin responses on day 1 were significantly higher during supplementation. After exercise, testosterone declined below resting values during supplementation. Cortisol decreased immediately postexercise on day 1; the response was diminished on days 2 and 3. Glucose and insulin were significantly elevated by 30 min during supplementation and remained stable during placebo. Insulin-like growth factor-I was higher during supplementatiom on days 2 and 3. These data indicate that protein-carbohydrate supplementation before and after training can alter the metabolic and hormonal responses to consecutive days of heavy-resistance exercise.

Influence of Resistance Exercise Volume on Serum Growth Hormone and Cortisol Concentrations in Women

1996 ◽  
Vol 10 (4) ◽  
pp. 256 ◽  
Author(s):  
Susan E. Mulligan ◽  
Steven J. Fleck ◽  
Scott E. Gordon ◽  
L. Perry Koziris ◽  
N. Travis Triplett-McBride ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Resistance Exercise ◽  
Serum Growth Hormone

Response of High-Affinity Growth Hormone Binding Protein to Acute Heavy Resistance Exercise

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S239
Author(s):  
Duncan N. French ◽  
Martyn R. Rubin ◽  
William J. Kraemer ◽  
Carl M. Maresh ◽  
Jeff S. Volek ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Resistance Exercise ◽  
Binding Protein ◽  
Hormone Binding ◽  
High Affinity ◽  
Growth Hormone Binding Protein ◽  
Hormone Binding Protein ◽  
Heavy Resistance Exercise

Characteristics of circulating growth hormone in women after acute heavy resistance exercise

2001 ◽  
Vol 281 (4) ◽  
pp. E878-E887 ◽  
Author(s):  
Wesley C. Hymer ◽  
William J. Kraemer ◽  
Bradley C. Nindl ◽  
James O. Marx ◽  
David E. Benson ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Resistance Exercise ◽  
Kidney Diseases ◽  
Chemical Reduction ◽  
Human Growth ◽  
Size Exclusion ◽  
Target Cells ◽  
Diagnostic Systems ◽  
Heavy Resistance Exercise

The effects of exercise on the molecular nature of secreted human growth hormone (GH) or its biological activity are not well understood. Plasma from women (average age 23.6 yr, n = 35), drawn before and after an acute heavy resistance exercise test, was fractionated by size exclusion chromatography into three size classes, namely, >60 kDa ( fraction A), 30–60 kDa ( fraction B), and <30 kDa ( fraction C), before GH assay. Concentrations of GH in these fractions, as well as in unfractioned plasma, were measured by the Nichols immunoradiometric assay, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) polyclonal competitive RIA, Diagnostic Systems Laboratory's immunofunctional assay (measures dimerization-capable species), and the rat tibial bioassay. Significantly increased circulating GH concentrations of two- to fourfold were observed when immunoassays in unfractionated plasma samples were used, but they showed no significant change with use of the rat tibial bioassay. Significant exercise-induced increases in GH were found in fractions B and C but not in fraction A. Because chemical reduction of the samples before GH immunoassay significantly increased GH concentrations in fractions B and C (Nichols and NIDDK kits) after exercise, it is concluded that exercise may specifically increase release of disulfide-linked hormone molecules and/or fragments. Finally, because most of the GH released after exercise was able to dimerize the GH receptor in vitro, it is also concluded that these forms have the two intact binding sites required to initiate signal transduction in target cells.

Maturity-Associated Variations in Resistance Exercise-Induced Hormonal Responses in Young Male Athletes

2021 ◽  
pp. 1-8
Author(s):  
Yuta Sekine ◽  
Norikazu Hirose
Keyword(s):  
High School ◽  
Growth Hormone ◽  
Resistance Exercise ◽  
Junior High School ◽  
Junior High ◽  
Human Growth ◽  
Male Athletes ◽  
Hormonal Responses ◽  
Exercise Induced ◽  
Cortisol Ratio

Purpose: To examine differences in resistance exercise-induced hormonal responses among young athletes according to their maturity levels. Materials and Methods: A total of 12 collegiate and 32 junior high school male athletes were enrolled. The junior high school participants were divided into pre–peak height velocity (PHV) and post-PHV groups, according to their PHV ages. The salivary testosterone, cortisol, and human growth hormone levels were analyzed before (pre), immediately after (post), and at 15 minutes after performing body weight resistance exercise. Results: The testosterone levels were higher in the collegiate than in the junior high school group (P < .01) and increased after 15 minutes of exercise (P < .01). A significant decrease in the cortisol levels postexercise in the junior high school groups (P < .01) and an increase in the human growth hormone levels at 15 minutes after exercise in the post-PHV group were observed (P < .01). In the collegiate and post-PHV groups, the testosterone-to-cortisol ratio increased post and at 15 minutes after exercise (P < .01). The testosterone-to-cortisol ratio values were higher in the collegiate than in the post-PHV (at preexercise and at 15 min after [P < .01]) and pre-PHV groups (at all times [P < .01]). Conclusion: Exercise-induced acute hormonal responses to resistance exercise may depend on individuals’ maturity levels, even in those having the same age.

Responses of IGF-I to endogenous increases in growth hormone after heavy-resistance exercise

1995 ◽  
Vol 79 (4) ◽  
pp. 1310-1315 ◽  
Author(s):  
W. J. Kraemer ◽  
B. A. Aguilera ◽  
M. Terada ◽  
R. U. Newton ◽  
J. M. Lynch ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Creatine Kinase ◽  
Resistance Exercise ◽  
Acute Exercise ◽  
Recovery Period ◽  
Exercise Protocol ◽  
Significant Relationships ◽  
Igf I ◽  
Heavy Resistance Exercise ◽  
And Control

The purpose of this study was to examine the effects of a heavy-resistance exercise protocol known to dramatically elevate immunoreactive growth hormone (GH) on circulating insulin-like growth factor I (IGF-I) after the exercise stimulus. Seven men (23.1 +/- 2.4 yr) volunteered to participate in this study. Each subject was asked to perform an eight-station heavy-resistance exercise protocol consisting of 3 sets of 10 repetition maximum resistances with 1-min rest between sets and exercises followed by a recovery day. In addition, a control day followed a nonexercise day to provide baseline data. Pre- and postexercise (0, 15, and 30 min) blood samples were obtained and analyzed for lactate, creatinine kinase, GH, and IGF-I. Postexercise values for lactate and GH were significantly (P < 0.05) elevated above preexercise and resting baseline values. The highest mean GH concentration after the heavy-resistance exercise protocol was 23.8 +/- 11.8 micrograms/l, observed at the immediate postexercise time point. Significant increases in creatine kinase were observed after the exercise protocol and during the recovery day. No significant relationships were observed between creatine kinase and IGF-I concentrations. No significant changes in serum IGF-I concentrations were observed with acute exercise or between the recovery and control days. Thus, these data demonstrate that a high-intensity bout of heavy-resistance exercise that increases circulating GH did not appear to affect IGF-I concentrations over a 24-h recovery period in recreationally strength-trained and healthy young men.

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