Gender differences in whole-body fat oxidation kinetics during exercise

2011 ◽  
Vol 36 (1) ◽  
pp. 88-95 ◽  
Author(s):  
Xavier Chenevière ◽  
Fabio Borrani ◽  
David Sangsue ◽  
Boris Gojanovic ◽  
Davide Malatesta
Keyword(s):  
Oxygen Uptake ◽  
Body Fat ◽  
Maximal Oxygen Uptake ◽  
Oxidation Kinetics ◽  
Fat Oxidation ◽  
Whole Body ◽  
Maximal Power ◽  
Maximal Power Output ◽  
Men And Women ◽  
Oxidation Rates

Discrepancies appear in studies comparing fat oxidation between men and women. Therefore, this study aimed to quantitatively describe and compare whole-body fat oxidation kinetics between genders during exercise, using a sinusoidal (SIN) model. Twelve men and 11 women matched for age, body mass index, and aerobic fitness (maximal oxygen uptake and maximal power output per kilogram of fat-free mass (FFM)) performed submaximal incremental tests (Incr) with 5-min stages and a 7.5% maximal power output increment on a cycle ergometer. Fat oxidation rates were determined using indirect calorimetry, and plotted as a function of exercise intensity. The SIN model, which includes 3 independent variables (dilatation, symmetry, translation) that account for the main quantitative characteristics of kinetics, was used to mathematically describe fat oxidation kinetics and to determine the intensity (Fatmax) eliciting the maximal fat oxidation (MFO). During Incr, women exhibited greater fat oxidation rates from 35% to 85% maximal oxygen uptake, MFO (6.6 ± 0.9 vs. 4.5 ± 0.3 mg·kg FFM−1·min−1), and Fatmax (58.1% ± 1.9% vs. 50.0% ± 2.7% maximal oxygen uptake) than men (p < 0.05). While men and women showed similar global shapes of fat oxidation kinetics in terms of dilatation and symmetry (p > 0.05), the fat oxidation curve tended to be shifted toward higher exercise intensities in women (rightward translation, p = 0.08). These results support the idea that women have a greater reliance on fat oxidation than men during submaximal exercise, but also indicate that this greater fat oxidation is shifted toward higher exercise intensities in women than in men.

scholarly journals Whole-body fat oxidation increases more by prior exercise than overnight fasting in elite endurance athletes

2016 ◽  
Vol 41 (4) ◽  
pp. 430-437 ◽  
Author(s):  
Ulrika Andersson Hall ◽  
Fredrik Edin ◽  
Anders Pedersen ◽  
Klavs Madsen
Keyword(s):  
Oxygen Uptake ◽  
Body Fat ◽  
Maximal Oxygen Uptake ◽  
Fat Oxidation ◽  
Endurance Athletes ◽  
Whole Body ◽  
Oxidation Rates ◽  
Prior Exercise ◽  
Overnight Fasting ◽  
Maximal Fat Oxidation

The purpose of this study was to compare whole-body fat oxidation kinetics after prior exercise with overnight fasting in elite endurance athletes. Thirteen highly trained athletes (9 men and 4 women; maximal oxygen uptake: 66 ± 1 mL·min−1·kg−1) performed 3 identical submaximal incremental tests on a cycle ergometer using a cross-over design. A control test (CON) was performed 3 h after a standardized breakfast, a fasting test (FAST) 12 h after a standardized evening meal, and a postexercise test (EXER) after standardized breakfast, endurance exercise, and 2 h fasting recovery. The test consisted of 3 min each at 30%, 40%, 50%, 60%, 70%, and 80% of maximal oxygen uptake and fat oxidation rates were measured through indirect calorimetry. During CON, maximal fat oxidation rate was 0.51 ± 0.04 g·min−1 compared with 0.69 ± 0.04 g·min−1 in FAST (P < 0.01), and 0.89 ± 0.05 g·min−1 in EXER (P < 0.01). Across all intensities, EXER was significantly higher than FAST and FAST was higher than CON (P < 0.01). Blood insulin levels were lower and free fatty acid and cortisol levels were higher at the start of EXER compared with CON and FAST (P < 0.05). Plasma nuclear magnetic resonance-metabolomics showed similar changes in both EXER and FAST, including increased levels of fatty acids and succinate. In conclusion, prior exercise significantly increases whole-body fat oxidation during submaximal exercise compared with overnight fasting. Already high rates of maximal fat oxidation in elite endurance athletes were increased by approximately 75% after prior exercise and fasting recovery.

Effects of 2 different prior endurance exercises on whole-body fat oxidation kinetics: light vs. heavy exercise

2012 ◽  
Vol 37 (5) ◽  
pp. 955-964 ◽  
Author(s):  
Xavier Chenevière ◽  
Fabio Borrani ◽  
David Droz ◽  
Boris Gojanovic ◽  
Davide Malatesta
Keyword(s):  
Body Fat ◽  
Oxidation Kinetics ◽  
Rest Period ◽  
Fat Oxidation ◽  
Cycle Ergometer ◽  
Whole Body ◽  
Incremental Test ◽  
Oxidation Rates ◽  
Maximal Fat Oxidation ◽  
Aerobic Power Output

This study aimed to compare the effects of 2 different prior endurance exercises on subsequent whole-body fat oxidation kinetics. Fifteen men performed 2 identical submaximal incremental tests (Incr2) on a cycle ergometer after (i) a ∼40-min submaximal incremental test (Incr1) followed by a 90-min continuous exercise performed at 50% of maximal aerobic power-output and a 1-h rest period (Heavy); and (ii) Incr1 followed by a 2.5-h rest period (Light). Fat oxidation was measured using indirect calorimetry and plotted as a function of exercise intensity during Incr1 and Incr2. A sinusoidal equation, including 3 independent variables (dilatation, symmetry and translation), was used to characterize the fat oxidation kinetics and to determine the intensity (Fatmax) that elicited the maximal fat oxidation (MFO) during Incr. After the Heavy and Light trials, Fatmax, MFO, and fat oxidation rates were significantly greater during Incr2 than Incr1 (p < 0.001). However, Δ (i.e., Incr2–Incr1) Fatmax, MFO, and fat oxidation rates were greater in the Heavy compared with the Light trial (p < 0.05). The fat oxidation kinetics during Incr2Heavy showed a greater dilatation and rightward asymmetry than Incr1Heavy, whereas only a greater dilatation was observed in Incr2Light (p < 0.05). This study showed that although to a lesser extent in the Light trial, both prior exercise sessions led to an increase in Fatmax, MFO, and absolute fat oxidation rates during Incr2, inducing significant changes in the shape of the fat oxidation kinetics.

scholarly journals Differences in whole-body fat oxidation kinetics between cycling and running

2010 ◽  
Vol 109 (6) ◽  
pp. 1037-1045 ◽  
Author(s):  
Xavier Chenevière ◽  
Davide Malatesta ◽  
Boris Gojanovic ◽  
Fabio Borrani
Keyword(s):  
Body Fat ◽  
Oxidation Kinetics ◽  
Fat Oxidation ◽  
Whole Body

Substrate metabolism during different exercise intensities in endurance-trained women

2000 ◽  
Vol 88 (5) ◽  
pp. 1707-1714 ◽  
Author(s):  
J. A. Romijn ◽  
E. F. Coyle ◽  
L. S. Sidossis ◽  
J. Rosenblatt ◽  
R. R. Wolfe
Keyword(s):  
Oxygen Uptake ◽  
Exercise Intensity ◽  
Maximal Oxygen Uptake ◽  
High Intensity ◽  
Fat Oxidation ◽  
High Intensity Exercise ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Oxidation Rates ◽  
Reported Data

We have studied eight endurance-trained women at rest and during exercise at 25, 65, and 85% of maximal oxygen uptake. The rate of appearance (Ra) of free fatty acids (FFA) was determined by infusion of [2H2]palmitate, and fat oxidation rates were determined by indirect calorimetry. Glucose kinetics were assessed with [6,6-2H2]glucose. Glucose Ra increased in relation to exercise intensity. In contrast, whereas FFA Ra was significantly increased to the same extent in low- and moderate-intensity exercise, during high-intensity exercise, FFA Ra was reduced compared with the other exercise values. Carbohydrate oxidation increased progressively with exercise intensity, whereas the highest rate of fat oxidation was during exercise at 65% of maximal oxygen uptake. After correction for differences in lean body mass, there were no differences between these results and previously reported data in endurance-trained men studied under the same conditions, except for slight differences in glucose metabolism during low-intensity exercise (Romijn JA, Coyle EF, Sidossis LS, Gastaldelli A, Horowitz JF, Endert E, and Wolfe RR. Am J Physiol Endocrinol Metab 265: E380–E391, 1993). We conclude that the patterns of changes in substrate kinetics during moderate- and high-intensity exercise are similar in trained men and women.

Aerobic fitness determines whole-body fat oxidation rate during exercise in the heat

2010 ◽  
Vol 35 (6) ◽  
pp. 741-748 ◽  
Author(s):  
Juan Del Coso ◽  
Nassim Hamouti ◽  
Juan Fernando Ortega ◽  
Ricardo Mora-Rodriguez
Keyword(s):  
Oxygen Uptake ◽  
Body Fat ◽  
Healthy Subjects ◽  
Fat Oxidation ◽  
Exercise Duration ◽  
Substrate Oxidation ◽  
Peak Oxygen Uptake ◽  
Total Energy Expenditure ◽  
Whole Body ◽  
Blood Samples

The purpose of this study was to determine whole-body fat oxidation in endurance-trained (TR) and untrained (UNTR) subjects exercising at different intensities in the heat. On 3 occasions, 10 TR cyclists and 10 UNTR healthy subjects (peak oxygen uptake = 60 ± 6 vs. 44 ± 3 mL·kg–1·min–1; p < 0.05) exercised at 40%, 60%, and 80% peak oxygen uptake in a hot, dry environment (36 °C; 25% relative humidity). To complete the same amount of work in all 3 trials, exercise duration varied (107 ± 4, 63 ± 1, and 45 ± 0 min for 40%, 60%, and 80% peak oxygen uptake, respectively). Substrate oxidation was calculated using indirect calorimetry. Blood samples were collected at the end of exercise to determine plasma epinephrine ([EPI]plasma) and norepinephrine ([NEPI]plasma) concentrations. The maximal rate of fat oxidation was achieved at 60% peak oxygen uptake for the TR group (0.41 ± 0.01 g·min–1) and at 40% peak oxygen uptake for the UNTR group (0.28 ± 0.01 g·min–1). TR subjects oxidized absolutely (g·min–1) and relatively (% of total energy expenditure) more fat than UNTR subjects at 60% and 80% peak oxygen uptake (p < 0.05). At these exercise intensities, TR subjects also had higher [NEPI]plasma concentrations than UNTR subjects (p < 0.05). In the heat, whole-body peak fat oxidation occurs at higher relative exercise intensities in TR than in UNTR subjects (60% vs. 40% peak oxygen uptake). Moreover, TR subjects oxidize more fat than UNTR subjects when exercising at moderate to high intensities (>60% peak oxygen uptake).

scholarly journals Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Matthew Douglas Bruss ◽  
Cyrus F Khambatta ◽  
Ishita Aggarwal ◽  
Marc K Hellerstein
Keyword(s):  
Fatty Acid ◽  
Body Fat ◽  
Calorie Restriction ◽  
Fatty Acid Synthesis ◽  
Fat Oxidation ◽  
Acid Synthesis ◽  
Whole Body ◽  
Oxidation Rates

scholarly journals Maximal power output during incremental cycling test is dependent on the curvature constant of the power–time relationship

2015 ◽  
Vol 40 (9) ◽  
pp. 895-898 ◽  
Author(s):  
Kristopher Mendes Souza ◽  
Ricardo Dantas de Lucas ◽  
Paulo Cesar do Nascimento Salvador ◽  
Luiz Guilherme Antonacci Guglielmo ◽  
Renato Aparecido Corrêa Caritá ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Power Output ◽  
Maximal Oxygen Uptake ◽  
Maximal Power ◽  
Maximal Power Output ◽  
Physically Active ◽  
Cycling Test ◽  
Time Relationship ◽  
Constant Work Rate ◽  
Male Subjects

The aim of this study was to investigate whether the maximal power output (Pmax) during an incremental test was dependent on the curvature constant (W′) of the power–time relationship. Thirty healthy male subjects (maximal oxygen uptake = 3.58 ± 0.40 L·min−1) performed a ramp incremental cycling test to determine the maximal oxygen uptake and Pmax, and 4 constant work rate tests to exhaustion to estimate 2 parameters from the modeling of the power–time relationship (i.e., critical power (CP) and W′). Afterwards, the participants were ranked according to their magnitude of W′. The median third was excluded to form a high W′ group (HIGH, n = 10), and a low W′ group (LOW, n = 10). Maximal oxygen uptake (3.84 ± 0.50 vs. 3.49 ± 0.37 L·min−1) and CP (213 ± 22 vs. 200 ± 29 W) were not significantly different between HIGH and LOW, respectively. However, Pmax was significantly greater for the HIGH (337 ± 23 W) than for the LOW (299 ± 40 W). Thus, in physically active individuals with similar aerobic parameters, W′ influences the Pmax during incremental testing.

scholarly journals Maximal oxygen uptake versus maximal power output in children

2008 ◽  
Vol 26 (13) ◽  
pp. 1397-1402 ◽  
Author(s):  
Magnus Dencker ◽  
Ola Thorsson ◽  
Magnus K. Karlsson ◽  
Christian Lindén ◽  
Per Wollmer ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Power Output ◽  
Maximal Oxygen Uptake ◽  
Maximal Power ◽  
Maximal Power Output

Determinants of maximal whole-body fat oxidation in elite cross-country skiers: Role of skeletal muscle mitochondria

2018 ◽  
Vol 28 (12) ◽  
pp. 2494-2504 ◽  
Author(s):  
Sune Dandanell ◽  
Anne-Kristine Meinild-Lundby ◽  
Andreas B. Andersen ◽  
Paul F. Lang ◽  
Laura Oberholzer ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Body Fat ◽  
Fat Oxidation ◽  
Whole Body ◽  
Muscle Mitochondria ◽  
Skeletal Muscle Mitochondria ◽  
Cross Country

scholarly journals Increasing skeletal muscle carnitine content in older individuals increases whole‐body fat oxidation during moderate‐intensity exercise

Aging Cell ◽  
2021 ◽  
Vol 20 (2) ◽  
Author(s):  
Carolyn Chee ◽  
Chris E. Shannon ◽  
Aisling Burns ◽  
Anna L. Selby ◽  
Daniel Wilkinson ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Body Fat ◽  
Fat Oxidation ◽  
Whole Body ◽  
Moderate Intensity ◽  
Older Individuals ◽  
Moderate Intensity Exercise
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