Incidence and inheritance of the 1/29 and 14/20 Robertsonian translocations in Canadian beef cattle

Genome ◽  
1987 ◽  
Vol 29 (3) ◽  
pp. 504-509 ◽  
Author(s):  
J. McWhir ◽  
R. B. Church ◽  
G. H. Coulter ◽  
C. C. Lin

Metaphase chromosomes were prepared from peripheral leukocyte cultures of 253 beef animals representing 21 breeds. A total of 10 Robertsonian translocations were identified. Nine were 1/29 fusions and one was a stable 14/20 fusion identified in several Simmentals. To our knowledge, the only other case of this translocation reported was also in the Simmental breed, suggesting that this fusion may be unique to the breed. A further 54 relatives of known 1/29 and 14/20 carriers were examined, revealing that both fusions were inherited by 50% of offspring of the heterozygous carrier. Heterozygous male 1/29 carriers left fewer calves than karyotypically normal bulls when used in natural service. Key words: Robertsonian translocation, cattle, chromosomes, fertility.

2016 ◽  
Vol 7 (1) ◽  
pp. 20
Author(s):  
Nur Rasminati
Keyword(s):  

<div class="WordSection1"><p><em>The research was conducted to know the number of the productive female beef cattle slaughtering at abattoir in DIY. All of the beef cattle which slaughtered along a month were used in this research. The result showed that the number of productive beef cattle slaughtered  up to 2 years old were 28.98%; 2 – 5 years old were 69.55%; more than 5 years old were 1.44%. The female beef cattle slaughtered were 54.58% and the male beef cattle slaughtered were 32.36%. The non productive beef cattle slaughtered were 13.04% including 5.79% male and 7.24% female. The Peranakan Ongole (PO) breed slaughtered was 60.36% (125 heads), Brahman Cross 16.42% (34 heads), Simmental 15.94% (33 heads), Brangus 2.42% (5 heads), Limousine 4.35% (9 heads) and PFH 0.48% (1 heads). The percentage of productive beef cattle slaughtering were 86.95% with female beef productive were 64.25% and the PO breed at 2 – 5 years old were the most slaughtered. It could be concluded that the productive female beef cattle slaughtering at abattoir in DIY was quite high, which may influence the breed resources of beef cattle.</em></p><p><em> </em></p><p><em>Key words : Productive beef cattle, slaughtering, abattoir, Yogyakarta</em></p></div><em><br clear="all" /> </em>


2009 ◽  
Vol 89 (3) ◽  
pp. 295-300 ◽  
Author(s):  
Kim L McLean ◽  
Sheila M Schmutz

Melanocortin 1 Receptor (MC1R) is considered to be the main gene controlling the production of eumelanin or phaeomelanin, resulting in black or red coat colour of cattle. The recessive red allele, e, codes for a nonfunctional receptor, which does not bind the agonist alpha-melanocyte stimulating hormone (α-MSH), allowing for the production of phaeomelanin, or red pigment, whereas the dominant ED allele binds α-MSH leading to the production of eumelanin. We hypothesized that black cattle would have more α-MSH bound to MC1R, which could result in more α-MSH binding to the appetite suppressing receptor, Melanocortin 4 Receptor. We genotyped 328 crossbred steers of various colours that were purchased at weaning and fed until slaughter. Black cattle of ED/ED or ED/e genotype had increased back fat and required significantly fewer days (15-25) on feed to reach a target fat level for slaughter than the red cattle. Red cattle of e/e genotype were found to have a significantly larger longissimus dorsi (l. dorsi), shipping weight and hot carcass weight. Differences were comparable whether black versus red coat colour or MC1R genotype were used as the criteria for the group of cattle. Key words: Coat colour, MC4R, MC1R, α-MSH, shipping weight


1990 ◽  
Vol 70 (3) ◽  
pp. 963-965
Author(s):  
J. C. OLTHOFF ◽  
G. H. CROW ◽  
G. W. RAHNEFELD

Lines within a breed which differ in their level of performance may require different age-of-dam adjustment factors in the same way that different breeds do. Age-of-dam adjustments calculated from a control and a yearling weight selection line indicated lower values in the selected line for calf birth weight, weaning weight and yearling weight for 2- and 4-yr-old dams. Trends for adjustment factors in each line over time were generally not significant but tended to diverge. Age-of-dam adjustment factors within a breed may need to be reevaluated at intervals as levels of performance change. Key words: Beef cattle, age of dam adjustment, selection, yearling weight


2020 ◽  
Vol 77 (23) ◽  
pp. 4765-4785
Author(s):  
Ewa Wiland ◽  
Marta Olszewska ◽  
Tomasz Woźniak ◽  
Maciej Kurpisz

Abstract In men with oligozoospermia, Robertsonian translocations (RobTs) are the most common type of autosomal aberrations. The most commonly occurring types are rob(13;14) and rob(14;21), and other types of RobTs are described as ‘rare’ cases. Based on molecular research, all RobTs can be broadly classified into Class 1 and Class 2. Class 1 translocations produce the same breakpoints within their RobT type, but Class 2 translocations are predicted to form during meiosis or mitosis through a variety of mechanisms, resulting in variation in the breakpoint locations. This review seeks to analyse the available data addressing the question of whether the molecular classification of RobTs into Classes 1 and 2 and/or the type of DD/GG/DG symmetry of the involved chromosomes is reflected in the efficiency of spermatogenesis. The lowest frequency value calculated for the rate of alternate segregants was found for rob(13;15) carriers (Class 2, symmetry DD) and the highest for rob(13;21) carriers (Class 2, DG symmetry). The aneuploidy values for the rare RobT (Class 2) and common rob(14;21) (Class 1) groups together exhibited similarities while differing from those for the common rob(13;14) (Class 1) group. Considering the division of RobT carriers into those with normozoospermia and those with oligoasthenozoospermia, it was found that the number of carriers with elevated levels of aneuploidy was unexpectedly quite similar and high (approx. 70%) in the two subgroups. The reason(s) that the same RobT does not always show a similar destructive effect on fertility was also pointed out.


2001 ◽  
Vol 81 (3) ◽  
pp. 335-343 ◽  
Author(s):  
J. A. Small ◽  
J. D. Ambrose ◽  
W. P. McCaughey ◽  
D. R. Ward ◽  
W. D. Sutherland ◽  
...  

Trials were conducted in the spring (May; n = 324) and fall (October; n = 132) with crossbred continental-type beef cows assigned on the basis of parity and postpartum interval to one of three timed-AI treatments and one of two post-AI treatments. The timed-AI treatments were: (DPG) double (14 d apart) PGF2α (Lutalyse®) and AI (day = 0) 72 h after the second PGF2α (day –3); (OVS) Ovsynch® with the second GnRH (Factrel®) at 48 h and AI at 66 h; and (BRC) the same as OVS except that the second GnRH was given at the time of AI. Half of the cows within each treatment were given GnRH on day 14. Plasma progesterone concentrations were determined for the day of the first injection and on days –3, 0, 14, and 21. Timed-AI pregnancy was diagnosed by ultrasonography at day 42 and confirmed at calving. For DPG, OVS and BRC, PGF2α responder rates were 75.9, 51.4 and 71.3%, respectively, in spring (P < 0.05) and 70.4, 70.4 and 59.1% in fall (P > 0.05), and AI pregnancy rates were 28.7, 44.9 and 44.4% in spring (P< 0.05) and 25.0, 40.9 and 43.2% in fall (P > 0.05). Post-AI GnRH had no significant effect on pregnancy or conception rates or day 21 progesterone. The use of GnRH in the PGF2α based timed-AI program improved pregnancy rates and the BRC treatment was as effective as OVS. Neither postpartum interval nor initial progesterone concentration influenced (P >0.05) the effect of GnRH on AI pregnancy rate, and GnRH had no effect (P > 0.05) on twinning rate or gender ratio. Key words: Beef cows, estrous synchronization, pregnancy, timed-AI, progesterone


1993 ◽  
Vol 73 (4) ◽  
pp. 971-975 ◽  
Author(s):  
G. W. Rahnefeld ◽  
Doug Ward ◽  
G. M. Weiss

The following were compared as measures of cow productivity: (A) calf weaning weight per mating opportunity; (B) calf weaning weight per mating opportunity with cow weight at weaning as a covariate; (C) calf weaning weight per mating opportunity per unit of cow weight at weaning; and (D) calf weaning weight per mating opportunity per cow metabolic weight (kg0.75) at weaning. Results indicate that the method described under (C) is best at reducing error followed closely by the method described under (D). The least satisfactory measure of cow productivity was (B). Key words: Beef cattle, cow efficiency, productivity


2000 ◽  
Vol 80 (1) ◽  
pp. 19-24 ◽  
Author(s):  
P. K. Charagu ◽  
D. H. Crews Jr. ◽  
R. A. Kemp ◽  
P. B. Mwansa

Pre-slaughter ultrasound and carcass measurements of ribeye area (REA) and backfat (FAT) were recorded on composite beef bulls (n = 60), heifers (n = 60) and steers (n = 60). Breed composition of the composite was: 0.44 British (Hereford, Angus and Shorthorn) 0.25 Charolais, 0.25 Simmental and 0.06 Limousin. The Aloka SSD-1100 (AL) and the Tokyo Keiki CS 3000 (TK) ultrasound machines were compared by evaluating the difference between ultrasound and carcass measurements (bias), and the standard error of prediction (SEP). AL under-predicted REA in all three sexes while TK overpredicted heifers and steers and underpredicted bulls. Both machines were similar in accuracy among bulls for REA. For FAT AL underpredicted all three sexes while TK underpredicted heifers and had very small bias for bulls and steers. SEP for FAT were similar for both machines. Both machines underpredicted REA in larger muscled cattle and overpredicted in smaller-muscled cattle. Both machines also underpredicted FAT in fatter animals and overpredicted FAT in leaner animals. Machines were similar in accuracy among cattle with larger REA but differed significantly (P < 0.05) among smaller-muscled cattle. Machines were comparable in accuracy among animals of all FAT sizes. This study demonstrates that there is an important relationship between machine and the size and depth of muscle and backfat, respectively, and consequently between machine and sex, in accuracy of ultrasound prediction. Key words: Beef cattle, ultrasound, accuracy, back fat, ribeye area


2017 ◽  
Vol 20 (1) ◽  
pp. 43-50 ◽  
Author(s):  
B Wang ◽  
B Nie ◽  
D Tang ◽  
R Li ◽  
X Liu ◽  
...  

Abstract The frequency of the Robertonian (ROB) translocation in newborn babies is approximately one in 1000. Robertsonian translocation is an unusual type of chromosome rearrangement caused by two particular chromosomes joining together. The aim of the study was to analyze the segregation of the ROB translocations in 13 male carriers, and to verify a possible inter-chromosomal effect (ICE) of the ROB translocation on chromosomes 18, X, and Y. Thirteen male patients were included in the study. Multicolor fluorescent in situ hybridization (FISH) was used to analyze chromosomes 13, 14, 15, 21, 22, 18, X and Y in sperm. Among the heterozygous ROB translocation carriers, the frequency of normal/balanced spermatozoa resulting from alternate segregation varied between 70.4 and 85.2%. The frequency of unbalanced spermatozoa resulting from adjacent segregation varied between 14.8 and 29.6%. Increased frequencies of aneuploidy for a sex chromosome were found in 10 ROB translocation carriers (P2-P8, P10-P12). Increased frequencies of aneuploidy for chromosome 18 were found in10 ROB translocation carriers (P3-P9, P11-P13). In addition, increased frequencies of diploid were found in 11 ROB translocation carriers (P2-P9, P11-P13). Among the homozygous ROB translocation carriers, the rate of balanced spermatozoa was 99.7% and the frequency of unbalanced spermatozoa was 0.3%. However, the frequencies of aneuploidy for a sex chromosome and chromosome 18 were normal. Despite the high number of normal/balanced frequencies, there remained many unbalanced spermatozoa resulting from alternate segregation. The ROB translocation carriers may be at an increased risk for ICE. Robertsonian translocation homozygosity could be seen as a potential speciation in humans with 44 chromosomes.


2000 ◽  
Vol 80 (1) ◽  
pp. 191-193
Author(s):  
J. J. Tosh ◽  
R. A. Kemp

Genetic trends for weaning weight were determined in two herds of multibreed beef cattle that originated from a common base and were subject to mutual breeding policies in separate environments. The herds diverged for the direct though not the maternal genetic component of weaning weight within the 13-yr period examined; in the final year, the difference (P < 0.001) between the herds was almost 3 kg. This could have been partly due to unequal selection differentials and generation intervals. Results suggested the extent of natural selection also differed between the two environments. Key words: Beef cattle, crossbreeding, genetic trends, selection, weaning weight


1994 ◽  
Vol 74 (4) ◽  
pp. 621-632 ◽  
Author(s):  
J. A. Newman ◽  
A. K. W. Tong ◽  
S. D. M. Jones ◽  
G. W. Rahnefeld ◽  
D. R. C. Bailey ◽  
...  

Breed-of-dam and sex-of-calf effects are reported based on observation of 2007 heifer and steer carcasses. The carcasses were derived from Limousin-sired calves born to dams representing 15 F1 and backcross genotypes reared at two locations over a period of 5 yr. The calves represented Hereford × Angus, Charolais × Shorthorn, Simmental × Shorthorn and all backcross combinations involving Charolais or Simmental with Hereford, Angus or Shorthorn. Carcass traits were analyzed on an unadjusted, a constant hot-carcass weight, and a constant rib-fat depth basis. The slaughter criteria dictated that steers were heavier at slaughter than heifers. They also exhibited higher dressing yield, greater longissimus thoracis area, and lower fat depth. Charolais and Simmental breeding was associated with less rib fat depth, greater longissimus thoracis area, a higher proportion of preferred cuts, less dissectible fat, more bone and more lean in the preferred cuts than British beef breeding. Within the European (Charolais and Simmental) and British beef (Hereford, Angus and Shorthorn) breed groups, breed effects were smaller, but for carcass composition traits they were frequently significant. When compared with Simmental, Charolais breeding tended to be associated with less marbling, less rib fat depth, less dissectible fat and more lean in the preferred cuts. Among the British beef breeds, Hereford was associated with the highest proportion of preferred cuts, Shorthorn with the lowest rib fat depth — but the highest dissectible fat — and Angus with the most marbling, the greatest longissimus thoracis area and the lowest bone content. This research has demonstrated that breed effects for carcass composition traits tend to be additive and that a significant effect may be associated with substitution of as little as one-eighth of the breed composition. Key words: Beef cattle, slaughter traits, carcass traits, breed type, crossbred dam, backcross dam


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