ENZYME HETEROZYGOSITY ASSOCIATED WITH GROWTH AT DIFFERENT DEVELOPMENTAL STAGES IN OYSTERS

1982 ◽  
Vol 24 (4) ◽  
pp. 451-458 ◽  
Author(s):  
Shiva M. Singh
Keyword(s):  
Growth Rate ◽  
Prince Edward Island ◽  
Developmental Stages ◽  
Age Groups ◽  
Age Group ◽  
Cape Breton ◽  
Random Samples ◽  
Specific Mortality ◽  
One Year ◽  
Polymorphic Enzymes

Following our earlier reports on one-year-old oyster populations of Prince Edward Island (Singh and Zouros, 1978, 1981; Zouros et al., 1980), cohorts of three-year classes were studied from Cape Breton, Nova Scotia. Random samples of about 200 individuals from each year class were analyzed for four polymorphic enzymes. A number of generalizations emerged. There was a general deficiency of heterozygotes in the three age groups and this deficiency decreased with age (reflecting reduction in heterozygote deficiency). This suggests genotype-specific mortality during ontogeny. The deficiency of heterozygotes was more pronounced in slower growing, lighter individuals than in faster growing, heavier individuals. The number of heterozygous loci per individual was positively correlated with mean growth rate. The variance in weight was lower in heterozygotes; it decreased with increase in number of heterozygous loci in a given age group. Overdominance in growth rate appears to be the most plausible explanation for these observations.

scholarly journals One Year of the COVID-19 Pandemic in Galicia: A Global View of Age-Group Statistics during Three Waves

2021 ◽  
Vol 18 (10) ◽  
pp. 5104
Author(s):  
Iván Area ◽  
Henrique Lorenzo ◽  
Pedro J. Marcos ◽  
Juan J. Nieto
Keyword(s):  
Intensive Care Unit ◽  
Hospital Admissions ◽  
Age Groups ◽  
Age Group ◽  
Nw Spain ◽  
The Past ◽  
Global View ◽  
Time Period ◽  
Key Variables ◽  
One Year

In this work we look at the past in order to analyze four key variables after one year of the COVID-19 pandemic in Galicia (NW Spain): new infected, hospital admissions, intensive care unit admissions and deceased. The analysis is presented by age group, comparing at each stage the percentage of the corresponding group with its representation in the society. The time period analyzed covers 1 March 2020 to 1 April 2021, and includes the influence of the B.1.1.7 lineage of COVID-19 which in April 2021 was behind 90% of new cases in Galicia. It is numerically shown how the pandemic affects the age groups 80+, 70+ and 60+, and therefore we give information about how the vaccination process could be scheduled and hints at why the pandemic had different effects in different territories.

scholarly journals A first-year dornase alfa treatment impact on clinical parameters of patients with cystic fibrosis: the Brazilian cystic fibrosis multicenter study

2013 ◽  
Vol 31 (4) ◽  
pp. 420-430 ◽  
Author(s):  
Tatiana Rozov ◽  
Fernando Antônio A. e Silva ◽  
Maria Angélica Santana ◽  
Fabíola Villac Adde ◽  
Rita Heloisa Mendes
Keyword(s):  
Cystic Fibrosis ◽  
Emergency Room ◽  
Age Groups ◽  
Forced Expiratory Volume ◽  
First Year ◽  
Age Group ◽  
Emergency Room Visits ◽  
Dornase Alfa ◽  
Pulmonary Exacerbations ◽  
One Year

OBJECTIVE: To describe the clinical impact of the first year treatment with dornase alfa, according to age groups, in a cohort of Brazilian Cystic Fibrosis (CF) patients. METHODS: The data on 152 eligible patients, from 16 CF reference centers, that answered the medical questionnaires and performed laboratory tests at baseline (T0), and at six (T2) and 12 (T4) months after dornase alfa initiation, were analyzed. Three age groups were assessed: six to 11, 12 to 13, and >14 years. Pulmonary tests, airway microbiology, emergency room visits, hospitalizations, emergency and routine treatments were evaluated. Student's t-test, chi-square test and analysis of variance were used when appropriated. RESULTS: Routine treatments were based on respiratory physical therapy, regular exercises, pancreatic enzymes, vitamins, bronchodilators, corticosteroids, and antibiotics. In the six months prior the study (T0 phase), hospitalizations for pulmonary exacerbations occurred in 38.0, 10.0 and 61.4% in the three age groups, respectively. After one year of intervention, there was a significant reduction in the number of emergency room visits in the six to 11 years group. There were no significant changes in forced expiratory volume in one second (VEF1), in forced vital capacity (FVC), in oxygen saturation (SpO2), and in Tiffenau index for all age groups. A significant improvement in Shwachman-Kulczychi score was observed in the older group. In the last six months of therapy, chronic or intermittent colonization by P. aeruginosa was detected in 75.0, 71.4 and 62.5% of the studied groups, respectively, while S. aureus colonization was identified in 68.6, 66.6 and 41.9% of the cases. CONCLUSIONS: The treatment with dornase alfa promoted the maintenance of pulmonary function parameters and was associated with a significant reduction of emergency room visits due to pulmonary exacerbations in the six to 11 years age group, with better clinical scores in the >14 age group, one year after the intervention.

scholarly journals Seroprevalence of Toxoplasma gondii in Dairy Cattle with Reproductive Problems in Sudan

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Abdelghafar M. Elfahal ◽  
Amira M. Elhassan ◽  
Mohammed O. Hussien ◽  
Khalid A. Enan ◽  
Azza B. Musa ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Dairy Cattle ◽  
Age Groups ◽  
Parasitic Infections ◽  
Age Group ◽  
Infection Rates ◽  
Herd Level ◽  
Individual Level ◽  
Reproductive Disease ◽  
One Year

Toxoplasmosis, caused by Toxoplasma gondii, is one of the most common parasitic infections of humans and other warm-blooded animals in most parts of the world. The disease is common among sheep and goats and it is recognized as one of the major causes of reproductive failure in these animals. Cattle, on the other hand, can be infected, but abortion or perinatal mortality has not been recorded. This survey was carried out to study the prevalence of this disease in cattle in Khartoum and Gazira States (Sudan). 181 sera samples collected from dairy cattle with reproductive problems were assayed for antibodies to T. gondii by ELISA. The prevalence rate of T. gondii antibodies in cattle at herd level was 44.8% (13/29). Herd level infection rates were 50% and 33.3% in Khartoum and Gazira States, respectively. The overall prevalence of T. gondii at individual level in both states was 13.3% (24/181). The prevalence was 12.7% (17/134), was 14.9% (7/47) in Khartoum and Gazira State, respectively. There was significantly higher (P<0.05) prevalence of T. gondii antibodies in the age group less than one year old (36.4%) than in other age groups and in males (30.8%) than in females (11.9%) while no significant relationship was discerned regarding breed, location, season, or signs of reproductive disease.

Quality of life in young men after radical prostatectomy: Results from the CaPSURE registry

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 4576-4576 ◽  
Author(s):  
J. L. Wright ◽  
D. W. Lin ◽  
J. E. Cowan ◽  
J. Duchane ◽  
P. R. Carroll ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Age Groups ◽  
Older Men ◽  
Multivariate Model ◽  
Age Group ◽  
Younger Men ◽  
One Year

4576 Background: Over the past two decades, the age at diagnosis and treatment of men with prostate cancer (CaP) has steadily declined. Previous work suggests that younger men have similar or improved pathologic and clinical outcomes compared to older men. The literature on quality of life (QOL) following local treatment for CaP has primarily focused on comparing treatment modalities rather than specific age groups. This analysis explored QOL outcomes in younger men following primary curative treatment for localized prostate cancer. Methods: This was a secondary analysis of a prospectively collected cohort from the CaPSURE (Cancer of the Prostate Strategic Urologic Endeavor) registry. Men who underwent radical prostatectomy (RP) for localized disease and completed the UCLA Prostate Cancer Index (PCI) pre- and one-year post-surgery were identified. Men were grouped based on age (< 55, 55–64, ≥ 65 years). A severe decline in PCI domains from pre- to post-RP was defined as a decrease of one standard deviation from the pre-RP score. PCI scores were compared across age groups, and a multivariate model created to analyze the predictors of severe declines in PCI domains. Results: 1,143 men were identified, with 190, 526 and 427 men in the three age groups, respectively. Younger men had significantly higher mean scores one-year after RP in the urinary function (UF), urinary bother (UB) and sexual function (SF) domains of the PCI. The proportion of men with a severe decline in UF, UB and SF was not significantly different in the age groups (range 49–54%, 32–38%, 58–51% respectively). However, a severe decline in SB was more common in the youngest age group than in the oldest (54% vs. 36%, p < 0.01). With the youngest men as the reference group in the multivariate model, the oldest age group was 40% less likely to have a severe decline of SB (OR = 0.60, 95% CI 0.41–0.90, p = 0.04) but trended toward a higher risk of severe decline in UB (OR = 1.27, 95% CI 0.85–1.89, p = 0.08). Conclusions: Age predicts disease-specific QOL changes at one-year following RP. Younger men had significantly better mean UF, UB, and SF domain scores one-year after RP than did their older counterparts. Men < 55 years old are more likely than older men to experience a severe decline of sexual bother but trend toward a lower risk of a severe urinary bother. No significant financial relationships to disclose.

scholarly journals The Comparison of Accelerated Corneal Crosslinking Treatment for Progressive Keratoconus in the Pediatric and Adult Age Groups: One-Year Results

2021 ◽  
Author(s):  
Mustafa Berhuni ◽  
Cem Ozturkmen
Keyword(s):  
Visual Acuity ◽  
Corneal Thickness ◽  
Age Groups ◽  
Age Group ◽  
Preoperative Period ◽  
Adult Group ◽  
Adult Age ◽  
Pediatric Age Group ◽  
Significant Difference ◽  
One Year

Abstract Purpose: To investigate the short-term results of accelerated crosslinking (A-CXL) treatment for progressive keratoconus in the pediatric and adult age groups. Materials and methods: The records of the 62 eyes of 40 patients who had undergone the A-CXL procedure (9 mV/cm2, 10 min) for progressive keratoconus between January 2015 and January 2019 were evaluated retrospectively. The patients were divided into 2 groups as the pediatric group (aged 17 years or less) and the adult group (aged 18 years or more) for statistical analysis. Pre- and post- 12th month A-CXL best-corrected visual acuity (BCVA), maximum keratometry (Kmax), sim K1, sim K2, corneal thickness at the thinnest point (thCT), and corneal astigmatism (CA) values of the patient groups were recorded. Results: The 29 eyes of 16 patients were included in the pediatric group and the 33 eyes of 24 patients were included in the adult group. The mean age was 13.50±3.05 years in the pediatric group and 23.58±4.37 years in the adult group. A significant improvement in BCVA and a significant decrease in thCT values were present in both groups 12 months after the surgery compared to the preoperative period. A decrease was present in the Kmax, sim K1, sim K2 and CA values in the pediatric group, but was not statistically significant. The decrease in Kmax, sim K1 and sim K2 values compared to the preoperative period was significant in the adult group, but the decrease in CA values was not significant. When the two groups were compared at the end of 12 months, only the sim K1 value was significantly lower in the adult group, and there was no significant difference between the other measurements. Conclusions: Better visual acuity improvement, a higher flattening rate, and less progression occur after 12 months with A-CXL treatment for progressive keratoconus in the adult age group compared to the pediatric age group.

Youth's personal relationships, psychological symptoms, and the use of different substances: A population-based study

2021 ◽  
pp. 145507252110507
Author(s):  
Adriana del Palacio-Gonzalez ◽  
Mads Uffe Pedersen
Keyword(s):  
Substance Use ◽  
Alcohol Use ◽  
Emerging Adults ◽  
Peer Influence ◽  
Illicit Drugs ◽  
Developmental Stages ◽  
Age Groups ◽  
Close Friend ◽  
Age Group ◽  
Externalising Symptoms

Background: Externalising symptoms and peer influence are well-established predictors of youth's substance use in general. However, there is little integrative research that compares the relative contribution of psychological and social relationship characteristics as predictors of the use of specific substances among youth in different developmental stages. Methods: A representative sample of Danish adolescents ( n  =  1,168) and emerging adults (EA; n  =  1,878) reported last-month prevalence use of cigarettes, cannabis, and other illicit drugs (OID), and four indices of alcohol use. Predictor variables included internalising and externalising symptoms, and major characteristics of the youth's relationships (e.g., parental drug use, number of close friends). Results: Having a close friend who used illicit drugs, and high externalising symptoms, predicted the risk for using all substances across both age groups. Alcohol use was more consistently related to peer-related variables than to symptoms. Smoking cigarettes, cannabis use, and OIDs use were related to peer and symptom variables. Age group moderated some associations. Parental separation was related more strongly to alcohol use among adolescents than among EA, and higher internalising symptoms were more strongly related to smoking and using OIDs among adolescents than among EA. Male EAs had higher risk for using alcohol than female EAs. Conclusion: Beyond having a close friend who used illicit drugs, and externalising problems, the use of each substance was better explained by a different group of variables. There were few but important moderations by age group. The findings highlight the need for research on risk factors for substance use that is developmentally sensitive, particularly for adolescents, and for specific substances. Thus, interventions and policies should address social, developmental, and psychological factors.

EPIDEMIC SHIGELLA GASTROENTERITIS (BACILLARY DYSENTERY) IN AN ENDEMIC AREA

PEDIATRICS ◽  
1953 ◽  
Vol 11 (2) ◽  
pp. 145-153
Author(s):  
MILTON FEIG
Keyword(s):  
Endemic Area ◽  
Bacillary Dysentery ◽  
Age Groups ◽  
Population Group ◽  
Median Number ◽  
Clinical Aspects ◽  
Age Group ◽  
Significant Difference ◽  
General Population Group ◽  
One Year

The clinical aspects of acute bacillary dysentery as observed in an outbreak among a general population group in a highly endemic area are presented; age-specific clinical variations are noted. The onset was abrupt in all cases and all age-groups. The height of the illness in 84% of 106 cases was reached in 24 hours, more rapidly than in the "classical" form (3 to 5 days). The presence of blood in the stools was noted in about 25% of all cases; in about 25% of the 0 through 5 year age-group, 50% of the 6 through 10 year group, 37½% of the 11 through 15 year age-group, and 9 to 10% in the groups 16 years of age and over. The median number of stools was 9 to 10 daily, with no significant difference among the various age-groups. Fever was present in 65% of the children 10 years of age and under (55 cases), and in 35% of the older age-groups (40 cases). Vomiting is more frequent among the younger age-groups; weakness becomes a more frequent complaint with advancing age. The median duration of illness was 5.5 days in 100 cases. There was no correlation observed between age and duration. Recurrences are more frequently observed in the youngest age-groups—36% of all cases (14) under one year of age, 28% of 39 cases between 1-2 years of age. About 9% of the 26 and over age-group (34 cases) recurred, and practically none in the intervening groups. No relationship was observed between the tendency towards recurrences in households with multiple cases as compared with single cases. All the fatalities were under one year of age. Two deaths occurred in the cases studied, yielding an age-specific death rate of 14.3% for this group. Five other deaths in cases not included in this report are noted, all under one year of age; 2 caused by "infant diarrhea" and 3 by bronchopneumonia with "chronic diarrhea" as a contributing cause. The role of acquired immunity in the modification of bacillary dysentery can be evaluated from studies of attack rates and the clinical course of the disease, through age-specific groupings. Investigators should clearly define such basic terms as duration, recurrences, etc., when reporting so that necessary comparisons and/or data summation can be made.

The Descriptive Epidemiology and Outcomes of Hospitalized Burn Patients in Southern Turkey: Age-specific Mortality Patterns

2020 ◽  
Author(s):  
Kayhan Gurbuz ◽  
Mete Demir
Keyword(s):  
Mortality Rate ◽  
Descriptive Analysis ◽  
Age Groups ◽  
Total Body Surface Area ◽  
Multivariate Regression Analysis ◽  
Inhalation Injury ◽  
Burn Patients ◽  
Age Group ◽  
Specific Mortality ◽  
Fire Flame

Abstract The current descriptive analysis was designed to document the common epidemiologic characteristics and outcomes of burn injuries, and age-specific mortality patterns covering all age groups admitted for treatment to the Burn Center of Adana City Training and Research Hospital (ACTRH). Medical records were retrospectively analyzed. The patients were stratified into two age groups as pediatric and adults, and then into ten sub-age groups. Among the 946 patients of the study population, there were 24 mortalities with a mortality rate of 2.5%. Patients within the age range of 70-79 years had the highest mortality rate of 33.3%; followed by 60-69, 80+, 18-29, 10-17, and &lt;5 sub-age groups, whose mortality rates were, 13.0%, 7.8%, 7.2%, 2.4%, 0.5%, respectively. In terms of multivariate regression analysis of factors predicting mortality among burn patients in all age groups, fire-flame related burns, age ≥18 years, total body surface area burned ≥20 percent (TBSA ≥20%), the existence of inhalation injury, deep partially/full-thickness burns were found to be significant prognostic factors of mortality. The strongest association was seen in TBSA ≥60% segment (p&lt;0.0001), which had 25.9 times more death risk. As expected, a similar trend was detected when the age groups stratified into age groups, and the strongest association was in the 60+ sub-age group (p&lt;0.0001), whose had 5.84 times more likely death; followed by 29-59, 18-29 sub-age groups, with the ORs of 2.12 (95%CI=1.25-3.61), 2.08 (95%CI=1.90-4.05), respectively. Oppose to these findings; the 0-17 sub-age group was not found to have a statistically significant effect in predicting mortality.

scholarly journals Study of histopathological patterns of endometrium in abnormal uterine bleeding

2021 ◽  
Vol 10 (4) ◽  
pp. 1401
Author(s):  
Anitha S. ◽  
Pooja G. ◽  
Sowmya D.
Keyword(s):  
Histopathological Examination ◽  
Age Groups ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Research Centre ◽  
Age Group ◽  
Endometrial Sampling ◽  
Endometrial Pattern ◽  
Post Menopausal ◽  
One Year

Background: Abnormal uterine bleeding (AUB) is the commonest presenting symptom in gynaecology out- patient department. Endometrial sampling could be effectively used as the first diagnostic step in AUB. This study was done to evaluate histopathology of endometrium for identifying the endometrial causes of AUB. And also, to observe the incidence of various endometrial pathology in different age groups presenting with abnormal uterine bleeding.Methods: A one-year prospective study conducted in the department of obstetrics and gynaecologist in A. J. institute of medical sciences and research centre which included 200 cases of clinically diagnosed AUB patients. Histopathological examination of endometrial biopsies specimens was done, followed by clinical correlation.Results: The most common age group presenting with AUB was 41-50 years (43.84%). The commonest pattern in these patients was normal cycling endometrium (42.32%). The commonest pathology irrespective of the age group was disordered proliferative pattern (26.15%). Other causes identified atrophic endometrium (11.5%), benign endometrial polyp (5.38%), endometrial hyperplasia (5.41%), carcinomas (0.79%) and chronic endometritis (1.54%).Conclusions: The knowledge of endometrial pattern in a case of AUB helps to decide a plan of management. Endometrial sampling plays a very important role in management of AUB, especially in the age group of more than 40 years; i.e., the peri and post-menopausal age groups, where incidence of malignant or pre malignant conditions was noted to be the highest.

scholarly journals Study on spectrum of heart diseases in children aged 1 month to 12 years in a rural medical college in Southern India

2019 ◽  
Vol 6 (5) ◽  
pp. 2016
Author(s):  
Selvakumar R. ◽  
Vasanthamalar C. ◽  
Sreeman N.
Keyword(s):  
Heart Disease ◽  
Heart Diseases ◽  
Pulmonary Stenosis ◽  
Age Groups ◽  
Structural Abnormality ◽  
Age Group ◽  
Rheumatic Carditis ◽  
Author Study ◽  
Specific Distribution ◽  
One Year

Background: To study the pattern of heart diseases in children aged 1 month to 12 years of age and to assess the pattern, age and gender specific distribution of congenital heart diseases and acquired heart diseases in various age groups like infants, toddler, preschool and school children to prevent morbidity and mortality. To study the various complications associated with various types of heart diseases.Methods: This is a descriptive study of one-year duration in which children with suspicion of heart disease were subjected to ECG, Chest X ray and Echocardiogram. Patients with confirmed heart disease were included and the infants less than 1 month, CCF due to anaemia or without any structural abnormality were excluded.Results: The prevalence of heart disease was 0.9% in author study. VSD is the commonest acyanotic lesion in all age group observed and TOF is the commonest cyanotic lesion. Most of the cyanotic lesions were observed in less than one year. Most of the acyanotic lesions fall within 5 to 12 years. RHD and rheumatic carditis forms the major acquired lesion followed by dilated cardiomyopathy. VSD, ASD, PDA, TOF, Pulmonary stenosis, Rheumatic carditis and MR were predominant in females whereas Aortic stenosis (Bicuspid aortic valve), AV canal defect, TGA, TAPVC were predominant in males. Among the nutritional status 64.2% of patients from acyanotic group and 100% patients from cyanotic group were malnourished. 35% of acyanotic and 100% of cyanotic group were stunted.Conclusions: Acyanotic lesion is the commonest, among which VSD is most common. TOF is the common cyanotic CHD. More than half of the patients were asymptomatic in acyanotic group and presented in the 5- 12 years age group and diagnosed on the basis of clinical suspicion on routine health visits or for some other reason.

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